Antibacterial and Antioxidant Activity of Biosynthesized Silver Nanoparticles Produced by Aegle marmelos Fruit Peel Extract

2019 ◽  
Vol 9 (3) ◽  
pp. 329-344 ◽  
Author(s):  
Mamta Kushwah ◽  
Seema Bhadauria ◽  
K. P. Singh ◽  
M.S. Gaur
2015 ◽  
Vol 5 (2) ◽  
pp. 159-164 ◽  
Author(s):  
Shiv Shankar ◽  
Lily Jaiswal ◽  
Rangabhatla Sai Laxmi Aparna ◽  
Rangabhatla GunneswaraS V Prasad ◽  
Govindappa Prem Kumar ◽  
...  

2019 ◽  
Vol 30 (4) ◽  
pp. 247
Author(s):  
Liana Liana ◽  
Rizal Rizal ◽  
Wahyu Widowati ◽  
Fioni Fioni ◽  
Khainir Akbar ◽  
...  

Aging is a natural process in human life and is triggered by the presence of free radicals (ROS). The use of antioxidants from natural ingredients is one of the breakthroughs to overcome aging and counteract the harmful effects caused by the free radicals. This study aimed to determine and compare the antioxidant activity of H2O2 scavenging and hyaluronidase inhibition of red dragon fruit peel extract (DFPE) and kaempferol-3-o-rutinoside (KOR) compounds. Dragon fruit peel extract (DFPE) is obtained through extraction by maceration method using 70% ethanol solvent. The design of this study included antioxidant and anti-aging activity assay of EKBN and KOR at the series concentration of 15.63; 31.25; 62.50; 125; 250; 500 µg/mL through H2O2 scavenging, as well as the DFPE and KOR hyaluronidase inhibition assay at the series concentration of 5.21; 10.42; 20.83; 41.7; 83.33; 166.67 µg/mL. EKBN shows that the average activity of H2O2 scavenging is lower than KOR. In addition, the IC50 values of KOR for H2O2 scavenging is lower (351.46±2.30ug/mL) than DFPE (409.64±23.17ug/mL). While, KOR also has higher values of inhibitory activity than of the DFPE. However, the IC50 value of KOR for hyaluronidase inhibition activity was 84.07±10.46µg/mL, equivalent to the IC50 value of DFPE (85.32±10.24µg/mL). The presence of antioxidant and anti-aging activity in the EKBN is probably caused by betalain and the KOR compound itself contained in red dragon fruit. The results of the paired-samples T-test on antioxidant activity and anti-aging of DFPE and KOR showed non-significant difference. Thus, DFPE has an equivalent antioxidant and anti-aging through H2O2 scavenging and hyaluronidase activity as possessed by the KOR compound.


2013 ◽  
Vol 7 (3) ◽  
pp. 237-244 ◽  
Author(s):  
Subramanyam Dasari ◽  
K. A. Suresh ◽  
Mani Rajesh ◽  
C. Samba Siva Reddy ◽  
C. S. Hemalatha ◽  
...  

Author(s):  
Sumathi Ethiraj ◽  
Vandana Sridar

Objective: The main objective of this study was to analyze the phytochemical constituents, total phenol, total flavonoid, alkaloid content, in vitro antioxidant activity and high-performance liquid chromatography (HPLC) analysis of anonaine compound from the fruit peel extract of Annona reticulata L.Methods: Preliminary phytochemical analysis for alkaloids, cardiac glycosides, flavonoids, glycosides, phenols, saponins, steroids, tannins, and terpenoids was studied. Quantitative phytochemical analysis for total phenolics, total flavonoids and alkaloids was determined according to standard protocols. In vitro antioxidant potential was evaluated by assessing 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity by following standard procedure. HPLC analysis was carried out to identify a major metabolite, namely, anonaine compound from fruit peel extract of A. reticulata L.Results: Phytochemical screening of various extracts such as aqueous, ethanol, chloroform, acetone, and petroleum ether of fruit peel extracts revealed the presence of tannins, saponins, phenols, flavonoids, cardiac glycosides, coumarins, terpenoids, alkaloids, and steroids. Total phenol, flavonoid and alkaloid contents were quantitatively estimated which recorded maximum in Ooty accession (17.75±0.13 mg gallic acid equivalents/g, 13.97±0.21 mg quercetin equivalents/g, and alkaloid content of 6.92±0.14 mg/g), respectively. Among three accessions with five different solvents used, maximum antioxidant activity was found in aqueous peel extract (90.76±1.3%) from Ooty accession followed by others. The results of HPLC analysis in the fruit peel extract of A. reticulata proved the presence of the active principle, namely anonaine compound.Conclusion: Therefore, this study suggests the possibility of using fruit peel extracts of A. reticulata as a potent source of natural antioxidant and thus could prevent many free radical mediated diseases. The validated HPLC method can be used for routine quality control analysis.


Author(s):  
YENNI PUSPITA TANJUNG ◽  
ANDI IKA JULIANTI ◽  
IRNI ISNAYANTI ◽  
AGUSTIN R.

Objective: The aim of this study was to obtain a peel off gel facial mask preparation from Arabica coffee fruit peel extract that meets the requirements and to determine the antioxidant activity of Arabica coffee fruit peel extract and peel off gel facial mask preparation from coffee fruit peel extract Methods: In this study, three formulations of peel off gel facial mask were made with 3 variations in the concentration of coffee fruit peel extract, namely F1 (1%), F2 (2%), and F3 (3%). Furthermore, the preparation was evaluated for 28 d of storage at room temperature (25-30 °C) and cold temperature (8 °C) which included organoleptic, pH, spreading ability, homogeneity, viscosity, dry time, and antioxidant activity. Results: The results of the evaluation showed that F1, F2, and F3 met the requirements which included organoleptic, pH, spreading ability, homogeneity, viscosity, and dry time. The antioxidant activity of the coffee fruit peel extract was very strong (IC50 17.36 µg/ml). The antioxidant activity in the peel off gel facial mask sample of formula F1 (IC50 75.63 µg/ml) and formula F2 (IC50 50.71 µg/ml) was strong, and for formula F3 was very strong (IC50 21.44 µg/ml). Conclusion: All formulas met the evaluation requirements, arabica coffee fruit peel extract and peel of gel facial mask preparation (F3) have very strong antioxidant activity.


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