scholarly journals FREEZING POINTS OF ANTI-COAGULANT SALT SOLUTIONS

1935 ◽  
Vol 18 (4) ◽  
pp. 485-490 ◽  
Author(s):  
David I. Hitchcock ◽  
Ruth B. Dougan

By a method involving equilibration of ice and solution, and analysis of the solution, freezing point depressions of solutions of sodium citrate, oxalate, and fluoride have been determined over the range Δ = 0.45 to 0.65°C. Determinations with sodium chloride solutions have confirmed the accuracy of the method. In each case the freezing point depression is given, within 0.002°C., as a linear function of the concentration. By the use of these linear equations it is possible to prepare a solution of any of these four salts isotonic with a given biological fluid of known freezing point, provided the latter falls within the range studied.

1991 ◽  
Vol 45 ◽  
pp. 172-176 ◽  
Author(s):  
Jaakko Ilmari Partanen ◽  
Matti Jarmo Lindström ◽  
R. G. Hazell ◽  
Fredrik Lindgren ◽  
Michael Sjöström ◽  
...  

1989 ◽  
Vol 46 (12) ◽  
pp. 2104-2107 ◽  
Author(s):  
James A. Raymond

Pacific herring, Clupea harengus pallasi, were collected at three locations in Alaska and Japan in winter and spring to determine their degree of freezing resistance. Herring collected from waters whose temperatures ranged between 4.7 and −1.4 °C showed serum freezing points between −1.22 and −1.40°C. All freezing points were below those expected from measurements of serum osmolality, indicating that a noncolligative antifreeze was present that added between 0.28 and 0.61° to the freezing point depression. In addition, osmotically active substances other than sodium chloride contributed to the freezing point depression. in some of the samples.


1989 ◽  
Vol 54 (10) ◽  
pp. 2644-2647 ◽  
Author(s):  
Petr Schneider ◽  
Jiří Rathouský

In porous materials filled with water or water solutions of inorganic salts, water freezes at lower temperatures than under normal conditions; the reason is the decrease of water vapor tension above the convex meniscus of liquid in pores. The freezing point depression is not very significant in pores with radii from 0.05 μm to 10 μm (about 0.01-2.5 K). Only in smaller pores, especially when filled with inorganic salt solutions, this depression is important.


Parasitology ◽  
1966 ◽  
Vol 56 (1) ◽  
pp. 101-104 ◽  
Author(s):  
Madan M. Goil

The percentage change in weight, at 38·2 °C, in different concentrations of sodium chloride at different intervals, of a trematode, Gastrothylax crumenifer, from the reticulum of buffaloes has been recorded.A state of approximate isotonicity is reached between 0·4 and 0·5% sodium chloride.The osmotic pressure has also been expressed in terms of freezing-point depression.


1959 ◽  
Vol 39 (3) ◽  
pp. 384-394 ◽  
Author(s):  
D. H. Heinrichs

Two laboratory experiments were conducted to evaluate the reliability of amount of germination in solutions of varying osmotic pressure, as a means of separating alfalfa varieties into winter-hardiness classes. In one test 23 varieties or strains were studied, and in the other 36. It was found that significant differences exist between certain alfalfa varieties in their ability to germinate in sucrose or sodium chloride solutions of 3, 6, and 9 atmospheres. There is a general tendency for non-hardy varieties to germinate more rapidly and more completely than hardy ones but there are many exceptions to this trend. Germination in solutions of 6 atmospheres osmotic pressure at 5 days gave the best separation of varieties on the basis of their ability to germinate. Germination was generally better in solutions of sucrose at 6 atmospheres osmotic pressure than in solutions of sodium chloride of the same osmotic pressure but several varieties germinated equally well in either solution. The results indicate that germinating alfalfa in sugar or salt solutions is not a reliable method for differentiating alfalfa varieties into winter hardiness classes.


Author(s):  
Y. Hanawa ◽  
Y. Sasaki ◽  
S. Uchida ◽  
T. Funayoshi ◽  
M. Otsuji ◽  
...  

Abstract In this study, we investigated the freezing point depression of liquids in nanostructures using a new thermomechanical method. First, we experimentally determined the freezing points of water, cyclohexane, and a certain organic material (Chem.A) in nanoscale structures using DSC measurements. Thereafter, we formulated a new equation by improving the Gibbs–Thomson equation, which is the conventional formula for representing the freezing point depression of a liquid in nanostructures. We introduced a new term in this new equation to represent the increase in the kinetic energy of the liquid molecule as a result of collision between the liquid molecules and nanostructure walls. Subsequently, we evaluated the solid–liquid interface free energy of sublimation materials by fitting the theoretical freezing point derived from the new equation to experimental data. In this study, we succeeded in reproducing the experimental data of freezing point depression using the proposed equation. In particular, the freezing points of cyclohexane and Chem.A in the nanostructure were better fitted by this new equation at 10 nm or more compared with the conventional equation. Our results show that the interaction between the wall of the nanostructure and liquid molecules affects freezing point depression.


1987 ◽  
Vol 21 (12) ◽  
pp. 985-989 ◽  
Author(s):  
Daniel C. Robinson ◽  
Thomas L. Cookson ◽  
Joseph A. Grisafe

A guideline for the preparation of peripherally administered antibiotics in fluid-restricted patients was developed. A maximum osmolality of 560 mOsmol/kg was selected since this corresponds to the theoretical osmolality of dextrose 5% in NaCl 0.9%, a solution commonly administered peripherally without significant incidence of phlebitis. Percentage concentrations corresponding to 560 mOsmol/kg of 26 intravenous antibiotics were calculated using sodium chloride equivalents. The antibiotics were reconstituted using sterile water, dextrose 5%, and NaCl 0.9% to provide an osmolality of 560 mOsmol/kg. The resulting solutions were measured for osmolality using a freezing-point depression osmometer. A total of 78 solutions were prepared and measured in triplicate. Of the 78 measured osmolalities, 67 (86 percent) were within 20 percent of the desired 560 mOsmol/kg. Only two osmolalities were more than 10 percent above the projected value. The percentage concentrations of 26 antibiotics in three solutions corresponding to 560 mOsmol/kg are presented. A method is also provided for tailoring concentrations to achieve desired osmolalities other than 560 mOsmol/kg.


1925 ◽  
Vol 41 (6) ◽  
pp. 707-718 ◽  
Author(s):  
Russell L. Haden ◽  
Thomas G. Orr

Chemical changes are reported occurring in the blood of animals with obstruction of the jejunum, in which distilled water or sodium chloride solutions were introduced directly into the lumen of the intestine below the point of obstruction. Distilled water given daily from the beginning of the obstruction, had no influence on the development or course of the toxemia. 1 and 2 per cent salt solutions prevented a toxemia in uncomplicated cases. One animal so treated lived 30 days. Distilled water, given after the onset of toxemia, did not alter the progress or outcome of the toxemia. 10 per cent sodium chloride solution, administered after the onset of toxemia, controlled it in most cases for a long period. Hydrochloric acid had no effect on the course of the toxemia.


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