scholarly journals Current Status of Granulocyte (Neutrophil) Transfusion Therapy for Infectious Diseases

2001 ◽  
Vol 183 (2) ◽  
pp. 321-328 ◽  
Author(s):  
Kai Hübel ◽  
David C. Dale ◽  
Andreas Engert ◽  
W. Conrad Liles
Keyword(s):  
Infectious Diseases ◽  
Current Status ◽  
Transfusion Therapy

scholarly journals Natural killer cells as a therapeutic tool for infectious diseases - current status and future perspectives

Oncotarget ◽  
2018 ◽  
Vol 9 (29) ◽  
pp. 20891-20907 ◽  
Author(s):  
Stanislaw Schmidt ◽  
Lars Tramsen ◽  
Bushra Rais ◽  
Evelyn Ullrich ◽  
Thomas Lehrnbecher
Keyword(s):  
Natural Killer Cells ◽  
Infectious Diseases ◽  
Natural Killer ◽  
Current Status ◽  
Future Perspectives ◽  
Therapeutic Tool ◽  
Killer Cells

scholarly journals Overview of Plant-Derived Vaccine Antigens: Dengue Virus

2011 ◽  
Vol 14 (3) ◽  
pp. 400 ◽  
Author(s):  
Ravindra B Malabadi ◽  
Advaita Ganguly ◽  
Jaime A Teixeira da Silva ◽  
Archana Parashar ◽  
Mavanur R Suresh ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Dengue Virus ◽  
Neutralizing Antibodies ◽  
Vaccine Development ◽  
Low Cost ◽  
Current Status ◽  
Human Immune Deficiency Virus ◽  
Dengue Vaccine ◽  
New Methods ◽  
Vaccine Antigens

ABSTRACT - This review highlights the advantages and current status of plant-derived vaccine development with special reference to the dengue virus. There are numerous problems involved in dengue vaccine development, and there is no vaccine against all four dengue serotypes. Dengue vaccine development using traditional approaches has not been satisfactory in terms of inducing neutralizing antibodies. Recently, these issues were addressed by showing a very good response to inducing neutralizing antibodies by plant-derived dengue vaccine antigens. This indicates the feasibility of using plant-derived vaccine antigens as a low-cost method to combat dengue and other infectious diseases. The application of new methods and strategies such as dendritic cell targeting in cancer therapy, severe acute respiratory syndrome, tuberculosis, human immune deficiency virus, and malaria might play an important role. These new methods are more efficient than traditional protocols. It is expected that in the near future, plant-derived vaccine antigens or antibodies will play an important role in the control of human infectious diseases. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.

scholarly journals Emerging Natural Focal Infectious Diseases in Russia: A Medical–Geographical Study

2020 ◽  
Vol 17 (21) ◽  
pp. 8005
Author(s):  
Svetlana Malkhazova ◽  
Polina Pestina ◽  
Anna Prasolova ◽  
Dmitry Orlov
Keyword(s):  
Infectious Diseases ◽  
Disease Incidence ◽  
Spotted Fever ◽  
Hemorrhagic Fever ◽  
Ixodid Tick ◽  
European Russia ◽  
Current Status ◽  
North Caucasus ◽  
West Nile Fever ◽  
The North

In Russia, as in other countries, the problem of emerging natural focal infectious diseases (EIDs) became more acute toward the end of the 20th century. However, the situation in Russia is unknown to foreign readers, while the prevention and control of these diseases require international collaboration. The aim of the study is to provide a medical–geographical assessment of the distribution of the main natural focal EIDs in Russia, as well as to present the approaches used in the country to create aggregate maps of risk assessment. To consider its current status, we determined the most important natural focal EIDs for Russia (tick-borne encephalitis, ixodid tick-borne borrelioses, hemorrhagic fever with renal syndrome, Crimean–Congo hemorrhagic fever, West Nile fever, Astrakhan spotted fever, leptospiroses, and tularemia) and analyzed the patterns of their epidemic manifestation. As a result, a working classification of such infections and a series of maps showing the current situation of EID morbidity in Russia were created. To design an aggregated risk map, we developed an original mapping methodology and recalculated the model disease incidence by taking data from administrative units and adjusting them for natural geographical boundaries (biomes) for European Russia, and then evaluated the risk of infection for separate model diseases and for a set of them. The highest risk rates are confined to the northwest regions of European Russia, the Cis-Urals and the Volga region, which are naturally related to forest biomes, as well as to the southern steppe regions of the interfluves between the Volga and the Don, and the foothills of the North Caucasus.

scholarly journals Feline transfusion practice in South Africa : current status and practical solutions : continuing education

1999 ◽  
Vol 70 (3) ◽  
Author(s):  
T. Dippenaar
Keyword(s):  
South Africa ◽  
Transfusion Practice ◽  
Blood Type ◽  
Current Status ◽  
Hydration Status ◽  
Blood Collection ◽  
Transfusion Rate ◽  
Transfusion Therapy ◽  
Naturally Occurring ◽  
Disease Free

Blood transfusion therapy is often under-utilised in feline practice in South Africa. However, it is a technique that can be safely and effectively introduced in practice. Cats have naturally occurring allo-antibodies against the blood type that they lack, which makes blood typing, or alternatively cross-matching, essential before transfusions. Feline blood donors must be carefully selected, be disease free and should be sedated before blood collection. The preferred anticoagulant for feline blood collection is citrate-phosphatedextrose-adenine. Blood can either be administered intravenously or into the medullary cavity, with the transfusion rate depending on the cat's hydration status and cardiac function. Transfusion reactions can be immediate or delayed and they are classified as immunological or non-immunological. Indications, methods and techniques to do feline blood transfusions in a safe and economical way are highlighted.

scholarly journals Review of infectious diseases in refugees and asylum seekers—current status and going forward

2017 ◽  
Vol 38 (1) ◽  
Author(s):  
Andreas Halgreen Eiset ◽  
Christian Wejse
Keyword(s):  
Infectious Diseases ◽  
Asylum Seekers ◽  
Current Status ◽  
Refugees And Asylum Seekers

Pediatric infectious diseases in India: The current status and the way forward

2012 ◽  
Vol 4 (3) ◽  
pp. 99-100
Author(s):  
Vijay Yewale
Keyword(s):  
Infectious Diseases ◽  
Current Status ◽  
The Way

scholarly journals Granulocyte transfusions: current status

Blood ◽  
1980 ◽  
Vol 55 (1) ◽  
pp. 2-8 ◽  
Author(s):  
DJ Higby ◽  
D Burnett
Keyword(s):  
Bone Marrow ◽  
Acute Leukemia ◽  
Clinical Medicine ◽  
Bone Marrow Failure ◽  
Current Status ◽  
Granulocyte Transfusion ◽  
Transfusion Therapy ◽  
Neutropenic Patients ◽  
Ongoing Evaluation ◽  
Made In

Abstract Since granulocyte transfusions first became widely used in clinical medicine, there have been advances in the treatment of acute leukemia and improvement in prevention and management of infection in neutropenic patients. Improved understanding now exists concerning prognosis of infections in such patients, and advances have been made in procurement of granulocytes. Granulocyte transfusions should be given for specific indications, and used adjunctively to other established antiinfective therapy. Once initiated, transfusions should be given in adequate doses at daily intervals (at least) with ongoing evaluation and periodic reassessment of the whole antiinfective program. Serious complications of granulocyte transfusion therapy are relatively rare, but the physician should be prepared to manage them intelligently. Research continues in discerning exactly how granulocyte transfusion work, in preservation of granulocytes, and in delineation of immunologic phenomena affecting the efficiacy of such therapy. Granulocyte transfusions will continue to be important in the management of acute leukemia, and other reversible bone marrow failure states, and in marrow transplantation and autotransplantation.

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