scholarly journals Redefining the National Healthcare Safety Network’s Definition of Catheter-Associated Urinary Tract Infections: The Hazard of Including Candida Species

2014 ◽  
Vol 35 (11) ◽  
pp. 1433-1434
Author(s):  
Darcy Wooten ◽  
Jenifer Ramsey ◽  
Loren G. Miller
Author(s):  
Mohammad Salehi ◽  
Abdolmajid Ghasemian ◽  
Seyyed Khalil Shokouhi Mostafavi ◽  
Farshad Nojoomi ◽  
Danial Ashiani ◽  
...  

2021 ◽  
Vol 7 (4) ◽  
pp. 328-335
Author(s):  
IA Lawal ◽  
OA Osinupebi ◽  
OV Adeosun

Background: The presence of Candida species in the urine is termed candiduria, and it is a common form of urinary tract infection (UTI). Many other species of Candida organism apart from Candida albicans are known with increasing the occurrence of resistance to available antifungal agents. Objectives: To determine the prevalence and sensitivity pattern of Candida isolates obtained from urine samples of diagnosed urinary tract infections. Methods: Midstream urine of patients attending the Lagos University Teaching Hospital, Ikeja Lagos, were collected and inoculated on Sabouraud Dextrose Agar (SDA). Microbiological processing was done with Gram reaction, germ tube test, CHROME agar TM and sugar fermentation test using API 32C system. Antifungal susceptibility tests were done using the agar disc diffusion method. Results: Candida species were obtained from 36 (12.9%) of 280 patients with UTI. Candida albicans (CA) had the highest frequency (12; 33.3%) compared to 24 (66.7%) for Non-albicans Candida (NAC). The speciation of Candida using Chrome Agar showed some misidentification from the API32C identification, but there was a significant correlation between API32C and Chrome Agar methods (r = 0. 9793). Half of the C. albicans species were sensitive to fluconazole while C. hellenica was only sensitive to Nystatin. The C. parapsilopsis had the highest susceptibility pattern, with 86% and 71% for fluconazole and ketoconazole, respectively. Generally, ketoconazole had the highest effectiveness on Candida species. Conclusion: This study demonstrated the role of Candida species in UTIs and their high susceptibility to ketoconazole.


2015 ◽  
Vol 36 (10) ◽  
pp. 1236-1238 ◽  
Author(s):  
Surbhi Leekha ◽  
Michael Anne Preas ◽  
Joan Hebden

Presented in part: 20th Annual Meeting of the Society for Healthcare Epidemiology of America; Dallas, Texas; April 1–4, 2011.Infect Control Hosp Epidemiol 2015;36(10):1236–1238


Author(s):  
A. Arasi Samyuktha ◽  
V. Illamani ◽  
Chitralekha Saikumar

Community-acquired urinary tract infections (UTIs) are fastidious growing infections caused by Candida fungal overgrowth that frequently occur in immunosuppressed hospital patients. Although many factors account for the increases in these fungal infections, the leading causes include the rise in medical device usage, immunosuppressant drugs, and interventional procedures. The emergence of drug resistant in Candidal species, which is largely attributed to use of prolonged and inappropriate empirical therapy, has further complicated patient management. The regularity of urinary tract infections (UTIs) due to Candida species is growing and these infections are most common clinical outcome, particularly in hospitalized patients. The microbiological invasions in any tissue of the urinary tract extend from the renal cortex to the urethral meatus. Candida UTI or candiduria is a common finding in hospitalized patients. To find out the ratio of Candida albicans to non- albicans Candida species to correlate the risk factors to the Candida species associated and to analyze the speciation of Candida isolates using the Chrom agar is a differential culture media, with sugar assimilation test. Constant surveillance of candiduria is important as C. tropicalis is more invasive, can lead to fatal candidemia. Identification of Candida up to species level is essential, as it can give an idea to the clinicians about appropriate antifungal therapy. Our study showed a predominance of non-albicans Candida spp. of about 86%. C. tropicalis (62%) was the most common isolate obtained followed by C. albicans (14%), C. glabrata (10%), C. krusei (9%) and C. parapsilosis (5%). Indwelling urinary catheter was an important associated risk factor for non-albicans candiduria.


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