scholarly journals Influence of the femoral artery-graft junction patient-specific geometry on blood flow structure and wall shear stress

2021 ◽  
Vol 2103 (1) ◽  
pp. 012209
Author(s):  
Y F Ivanova ◽  
L G Tikhomolova ◽  
A D Yukhnev ◽  
E M Smirnov ◽  
R V Kalmikova ◽  
...  
Keyword(s):  
Blood Flow ◽  
Shear Stress ◽  
Wall Shear Stress ◽  
Femoral Artery ◽  
Numerical Study ◽  
Common Femoral Artery ◽  
Patient Specific ◽  
Geometrical Parameters ◽  
Artery Graft ◽  
Wall Shear

Abstract The paper presents a comparative numerical study of pulsatory blood flow in five patient-specific models of femoral-popliteal artery anastomosis. Three-dimensional geometric models of a proximal junction of the common femoral artery/graft were constructed on the bases of CT angiography. The influence of junction geometry on the blood flow and wall shear stress is analyzed. The ratio of the measured CFA and graft diameters and the junction angle are considered as the major geometrical parameters. Numerically calculated velocity fields are analyzed, and stagnant zones in the anastomoses flow are identified. Time-averaged distributions of wall shear stress and oscillatory shear index obtained for five patient-specific model are compared.

Numerical CFD / FSI Study of Teflon and Dacron for Use in the Femoral Artery Graft Procedure

2019 ◽  
Author(s):  
Sukwinder Sandhu ◽  
Kevin R. Anderson
Keyword(s):  
Shear Stress ◽  
Wall Shear Stress ◽  
Femoral Artery ◽  
Hoop Stress ◽  
Fluid Structure Interaction ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Implant Materials ◽  
Artery Graft ◽  
Wall Shear

Abstract This paper presents Fluid Structure Interaction modeling of candidate implant materials used in the femoral artery graft medical procedure. Two candidate implant materials, namely Teflon and Dacron are considered and modeled using Computational Fluid Dynamics (CFD) and structural Finite Element Analysis (FEA) to obtain Fluid Structure Interaction (FSI) developed stresses within the candidate materials as a result of non-Newtonian blood flowing in a pulsatile unsteady fashion into the femoral artery implant tube. The pertinent findings for a pulsatile velocity maximum magnitude of 0.3 m/s and period of oscillation of 2.75 sec are as follows. For the biological tissue the wall shear stress is found to be 2.15 × 104 Pa, the hoop stress is found to be 1.6 × 104 Pa. For the Teflon implant material, the wall shear stress is found to be 1.177 × 104 Pa, the hoop stress is found to be 2.2 × 104 Pa. For the Dacron implant material the wall shear stress is found to by 3.9 × 104 Pa, the hoop stress is found to be 2.17 × 104 Pa. Based upon the analysis herein the PTFE material would be recommended.

Computational Fluid Dynamics of a Vascular Access Case for Hemodialysis

2000 ◽  
Vol 123 (3) ◽  
pp. 284-292 ◽  
Author(s):  
Bogdan Ene-Iordache ◽  
Lidia Mosconi ◽  
Giuseppe Remuzzi ◽  
Andrea Remuzzi
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Blood Flow ◽  
Shear Stress ◽  
Wall Shear Stress ◽  
Radial Artery ◽  
Stress Gradient ◽  
Vascular Lesions ◽  
Patient Specific ◽  
Wall Shear

Vascular accesses (VA) for hemodialysis are usually created by native arteriovenous fistulas (AVF) or synthetic grafts. Maintaining patency of VA continues to be a major problem for patients with end-stage renal disease, since in these vessels thrombosis and intimal hyperplasia often occur. These lesions are frequently associated with disturbed flow that develops near bifurcations or sharp curvatures. We explored the possibility of investigating blood flow dynamics in a patient-specific model of end-to-end native AVF using computational fluid dynamics (CFD). Using digital subtraction angiographies of an AVF, we generated a three-dimensional meshwork for numerical analysis of blood flow. As input condition, a time-dependent blood waveform in the radial artery was derived from centerline velocity obtained during echo-color-Doppler ultrasound examination. The finite element solution was calculated using a fluid-dynamic software package. In the straight, afferent side of the radial artery wall shear stress ranged between 20 and 36 dynes/cm2, while on the inner surface of the bending zone it increased up to 350 dynes/cm2. On the venous side, proximal to the anastomosis, wall shear stress was oscillating between negative and positive values (from −12 dynes/cm2 to 112 dynes/cm2), while distal from the anastomosis, the wall shear stress returned within the physiologic range, ranging from 8 to 22 dynes/cm2. Areas of the vessel wall with very high shear stress gradient were identified on the bending zone of the radial artery and on the venous side, after the arteriovenous shunt. Secondary blood flows were also observed in these regions. CFD gave a detailed description of blood flow field and showed that this approach can be used for patient-specific analysis of blood vessels, to understand better the role of local hemodynamic conditions in the development of vascular lesions.

Blood Flow Manipulation in the Aorta With Coarctation and Arch Narrowing for Pediatric Subjects

2020 ◽  
Vol 88 (2) ◽  
Author(s):  
Yuxi Jia ◽  
Kumaradevan Punithakumar ◽  
Michelle Noga ◽  
Arman Hemmati
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Shear Stress ◽  
Wall Shear Stress ◽  
Aortic Arch ◽  
Flow Direction ◽  
Upper Body ◽  
Patient Specific ◽  
Shear Stresses ◽  
Wall Shear

Abstract The characteristics of blood flow in an abnormal pediatric aorta with an aortic coarctation and aortic arch narrowing are examined using direct numerical simulations and patient-specific boundary conditions. The blood flow simulations of a normal pediatric aorta are used for comparison to identify unique flow features resulting from the aorta geometrical anomalies. Despite flow similarities compared to the flow in normal aortic arch, the flow velocity decreases with an increase in pressure, wall shear stress, and vorticity around both anomalies. The presence of wall shear stresses in the trailing indentation region and aorta coarctation opposing the primary flow direction suggests that there exist recirculation zones in the aorta. The discrepancy in relative flowrates through the top and bottom of the aorta outlets, and the pressure drop across the coarctation, implies a high blood pressure in the upper body and a low blood pressure in the lower body. We propose using flow manipulators prior to the aortic arch and coarctation to lower the wall shear stress, while making the recirculation regions both smaller and weaker. The flow manipulators form a guide to divert and correct blood flow in critical regions of the aorta with anomalies.

scholarly journals Numerical Study of Non-Newtonian Blood Behavior in the Abdominal Aortic Bifurcation of a Patient-Specific at Rest

2017 ◽  
Vol 10 (1) ◽  
pp. 279-285 ◽  
Author(s):  
Carlos Oliveira ◽  
Armando A. Soares ◽  
André Simões ◽  
Sílvia Gonzaga ◽  
Abel Rouboa
Keyword(s):  
Shear Stress ◽  
Wall Shear Stress ◽  
Cardiovascular Health ◽  
Numerical Study ◽  
Shear Thinning ◽  
Patient Specific ◽  
Aortic Bifurcation ◽  
Low Velocity ◽  
Abdominal Aortic ◽  
Wall Shear

Background:The interaction of blood flow with walls of blood vessels is central for the development and maintenance of cardiovascular health. The analysis of wall shear stress is, therefore, fundamental in hemodynamic studies.Objective:The aim of this work is to study numerically the influence of the shear thinning blood properties on the hemodynamics in the abdominal aortic bifurcation for a patient-specific at rest.Methods:Were tested two models for the blood dynamic viscosity, one Newtonian and other non-Newtonian, with dependence on hematocrit and total protein minus albumin.Results and Conclusion:The results show the shear thinning behavior influence on the velocity distribution and wall shear stress. Furthermore, wall shear stress values are globally lower for non-Newtonian blood model at high velocity values than those for the Newtonian blood model. However, for low velocity values this behavior is inverted.

ESTIMATION OF WALL SHEAR STRESS OF COMPLIANT THORACIC AORTA WITH ANEURYSM

2020 ◽  
Vol 20 (03) ◽  
pp. 2050013
Author(s):  
AHMED BAKHIT ALANAZI ◽  
MOHAMED YACIN SIKKANDAR ◽  
MOHAMED IBRAHIM WALY
Keyword(s):  
Blood Flow ◽  
Shear Stress ◽  
Wall Shear Stress ◽  
Flow Pattern ◽  
Thoracic Aorta ◽  
Mass Flow ◽  
Tangential Force ◽  
Patient Specific ◽  
Hemodynamic Pattern ◽  
Wall Shear

In this paper, a numerical estimation of wall shear stress (WSS) in a compliant Thoracic Aorta (TA) with aneurysm is modeled and the hemodynamic pattern is studied using Computational Fluid Dynamics (CFD). Thoracic Aortic Aneurysm (TAA) is an excessively localized enlargement of TA caused by weakness in the arterial wall and it can rupture the inner wall intima and continue on to the outer wall adventitia. WSS is a tangential force exerted by blood flow on the vessel wall, and its estimation is clinically very important because any change in WSS is considered as a vital cue in the onset of aneurysm. In this work, a three-dimensional (3D) model of a TAA reconstructed from computed tomography (CT) images comprising of 600 slices with 1-mm resolution from neck to hip is considered and patient-specific simulations have been carried out in compliant TA under rest and exercise conditions. The findings show that the change in wall geometry was marginal due to variation in pressure forces inside and is not the primary source for expansion of an aneurysm. It was inferred that expansion was rather due to thinning of the wall, owing to damage caused to the inner lining of the tissues, at regions of high WSS. It was found that the geometry extraction is important as any change in length causes a corresponding variation in mass flow through it. Although mass conservation is maintained irrespective of the length, it does affect the rate of flow due to shifting in the pressure boundary conditions with the length as it varies the pressure inside the system. Modeling of the geometry is very important as the change in mass flow will affect the outlet velocity and strength of vortices. Surprisingly, the split-up of flow is consistent but the geometric change in the model has no effect on WSS values and flow pattern. The results of this study provide important information such as blood flow pattern and pressure drops in the compliant TA on WSS estimations with TAA diseases.

scholarly journals Asymmetric distribution of pathogenic low wall shear stress of the bilateral subclavian arteries: two case reports

2021 ◽  
Vol 49 (9) ◽  
pp. 030006052110425
Author(s):  
Huai Wu Yuan ◽  
Jin Xun Yao ◽  
Si Yu Huang ◽  
Min Yong Cui ◽  
Ren Jie Ji ◽  
...  
Keyword(s):  
Blood Flow ◽  
Shear Stress ◽  
Wall Shear Stress ◽  
Patient Specific ◽  
Asymmetric Distribution ◽  
Flow Volume ◽  
Risk Area ◽  
Blood Flow Volume ◽  
Wall Shear ◽  
The Right

The effects of increasing blood flow on the pathogenic wall shear stress (pWSS) of subclavian arteries (SAs) are currently unclear. Patient-specific models of the SA were constructed based on computed tomographic images from two patients. Using the Ansys Fluent 19.0 transient laminar flow solver, the finite volume method was chosen to solve the Navier–Stokes equation governing fluid behavior. The time-averaged wall shear stress, ratio of risk area, cumulative ratio of risk area ([Formula: see text]), ratio of risk time, and ratio contour of risk time were calculated to describe the temporal and spatial distributions of pWSS. Virtually all pWSS occurred during the diastolic phase. The [Formula: see text]was 2.3 and 1.29 times higher on the left than on the right in Patients 1 (P1) and 2 (P2), respectively. Increasing the blood flow volume of the left SA by 20%, 40%, and 60% led to a 9.27%, 15.10%, and 20.99% decrease in[Formula: see text] for P1 and a 5.74%, 11.55%, and 17.14% decrease in [Formula: see text] for P2, respectively, compared with baseline values. In conclusion, the left SA showed greater diastolic pWSS than the right SA, and increasing the blood flow volume reduced the pWSS in the left SA.

Influence of Hemodialysis Catheter Insertion on Hemodynamics in the Central Veins

2020 ◽  
Vol 142 (9) ◽  
Author(s):  
Min-Hyuk Park ◽  
Yue Qiu ◽  
Haoyao Cao ◽  
Ding Yuan ◽  
Da Li ◽  
...  
Keyword(s):  
Blood Flow ◽  
Shear Stress ◽  
Wall Shear Stress ◽  
Thrombus Formation ◽  
Patient Specific ◽  
Flow Disturbance ◽  
Computed Tomography Images ◽  
Relative Residence Time ◽  
Wall Shear ◽  
The Impact

Abstract Central venous catheter (CVC) related thrombosis is a major cause of CVC dysfunction in patients under hemodialysis. The aim of our study was to investigate the impact of CVC insertion on hemodynamics in the central veins and to examine the changes in hemodynamic environments that may be related to thrombus formation due to the implantation of CVC. Patient-specific models of the central veins with and without CVC were reconstructed based on computed tomography images. Flow patterns in the veins were numerically simulated to obtain hemodynamic parameters such as time-averaged wall shear stress (TAWSS), oscillating shear index (OSI), relative residence time (RRT), and normalized transverse wall shear stress (transWSS) under pulsatile flow. The non-Newtonian effects of blood flow were also analyzed using the Casson model. The insertion of CVC caused significant changes in the hemodynamic environment in the central veins. A greater disturbance and increase of velocity were observed in the central veins after the insertion of CVC. As a result, TAWSS and transWSS were markedly increased, but most parts of OSI and RRT decreased. Newtonian assumption of blood flow would overestimate the increase in TAWSS after CVC insertion. High wall shear stress (WSS) and flow disturbance, especially the multidirectionality of the flow, induced by the CVC may be a key factor in initiating thrombosis after CVC insertion. Accordingly, approaches to decrease the flow disturbance during CVC insertion may help restrain the occurrence of thrombosis. More case studies with pre-operative and postoperative modeling and clinical follow-up need to be performed to verify these findings. Non-Newtonian blood flow assumption is recommended in computational fluid dynamics (CFD) simulations of veins with CVCs.

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