Is This a Healthy Scientific Controversy or the “Savior” Syndrome at Play? COVID-19 and the Hydroxychloroquine Example

2021 ◽  
Vol 27 (3) ◽  
pp. 279-280
Author(s):  
Ivo G. Boneca
1989 ◽  
Vol 22 (3) ◽  
pp. 299-320 ◽  
Author(s):  
Robert Olby

The increasing attention which has been given to social history of science and to the sociological analysis of scientific activity has resulted in a renewed interest in scientific controversies. Furthermore, the rejection of the presentist view of history, according to which those contestants who took what we can identify, with the benefit of modern knowledge, as the ‘right’ stand in a controversy, were right and their opponents were ‘wrong’, left the subject of scientific controversies with many questions. What determines their emergence, course and resolution? When Froggatt and Nevin wrote on the Bio-metric-Mendelian controversy in 1971 they called their article ‘descriptive rather than interpretative’, so they avoided the very questions we would like to ask. Provine, in the same year, concentrated on the strong personalities of the contestants, their clashes, and the scientific arguments in play. But in 1975 Mackenzie and Barnes argued that the controversy could not be accounted for unless recourse was had to sociological factors. Their view has become widely known and figured prominently in 1982 in Steven Shapin's recital of the empirical achievements of the application of the sociological approach. I have returned to this subject because I do not yet feel altogether convinced by Mackenzie and Barnes' analysis. Even if their analysis of the controversy between Pearson and Bateson be accepted, it is not so obvious how effectively it can be used to explain the controversy between Weldon and Bateson, and I am not confident that it is adequate for an understanding of the evolution of their differing views of the mechanism of evolution.


1826 ◽  
Vol 10 (2) ◽  
pp. 314-329 ◽  
Author(s):  
James Hall

The public attention, animated by scientific controversy, has of late years been much directed to Geological subjects; and the certainty of many important facts, has in consequence been ascertained beyond dispute, which were formerly unknown, or at least involved in such obscurity, that no person could have ventured to assert them, without being charged with extravagance. But though, no doubt, many branches of this science still remain to be investigated, such inquiries may now be said to have acquired a considerable degree of consistency and interest, from the substantial basis upon which they have been found to rest.


2003 ◽  
Vol 9 (3) ◽  
pp. 194-205 ◽  
Author(s):  
Lundy Braun ◽  
Anna Greene ◽  
Marc Manseau ◽  
Raman Singhal ◽  
Sophie Kisling ◽  
...  

2021 ◽  
Vol 13 (4) ◽  
pp. 126-146
Author(s):  
E.A. Zikeeva ◽  
V.V. Selivanov ◽  
V.U. Kapustina ◽  
I.V. Strizhova

The use of modern didactic programs in mathematics in virtual reality (VR) requires approbation, proof of efficiency and environmental friendliness. VR properties: the ability to animate (perform actions with objects), interactivity and immersion in the information space are especially important for the training of future engineers, mathematicians and programmers. However, such programs today are still a poorly understood innovation, causing scientific controversy. The purpose of the presented study is to substantiate the effectiveness of didactic VR programs in teaching university students in technical areas, through determining the level of knowledge gained, the impact on the formation of educational motivation and the level of creativity among students in the study of higher mathematics. The methodological basis of the research was made up of the main provisions of the psychology of virtual reality, virtual ontology (V.A. Barabanshchikov, V.V. Selivanov). The assessment of changes in educational motivation was carried out using the methodology of A.A. Rean and V.A. Yakunin (modified by N.Ts. Badmaeva). Diagnostics of the level of creativity was carried out using the Johnson questionnaire, adapted by E.E. Tunic. As a result, it was shown that the students involved in the work with VR programs, at the level of reliable statistical significance, increase the indicators for the parameters of educational motivation, activity and creativity.


Hypertension ◽  
2012 ◽  
Vol 60 (suppl_1) ◽  
Author(s):  
Yan Hu ◽  
Minghong Li ◽  
R. Ariel Gomez ◽  
Maria Luisa S Sequeira Lopez

During early embryonic life, the heart starts to beat before an effective circulation is established, and the kidney starts to form its vasculature before it connects to the general circulation. We and others have shown a close lineage relationship between endothelial cells (ECs) and hematopoietic cells. In fact, during embryonic development erythroblasts bud from the endothelium of developing vessels, a process we termed hemovasculogenesis. Those studies suggested the possibility that embryonic organs may have hemogenic potential. To test this hypothesis, we performed lineage studies and colony forming unit (CFC) assays to trace the fate of hematopoietic stem cells (HSCs), erythroid cells, and ECs in heart and kidney from embryonic mice. Using ER-GFPcre mice that express both GFP and cre under control of the erythropoietin receptor locus in the erythroid cells, we identified hematopoietic progenitors (Hb+Nanog+) within nascent vessels in the early embryonic kidney and heart. Using EC-SCL-Cre-ERT transgenic mice that specifically express tamoxifen inducible Cre in EC progenitors, we found both circulating and non-circulating cells from the EC lineage in the early embryonic heart and kidney. CFC assays using HSC-SCL-Cre-ERT; mTmG mice (which express GFP in the cells from the HSC lineage upon tamoxifen induction) showed that both the embryonic kidney and heart possess HSCs. Further, transplantation studies of pre-vascular embryonic kidneys from EC-SCL-Cre-ERT;R26R mice under the kidney capsule of WT adult mice showed blood cells derived from the embryonic kidney suggesting that the embryonic kidney also possesses HSCs that originate in situ. These studies indicate that the embryonic kidney and heart function as hematopoietic organs during early embryogenesis. In addition to solve an important scientific controversy in our understanding of lineage/fate relationships in the developing embryo, these findings are relevant for tissue repair/regeneration and may help explain why under pathological circumstances, hematopoiesis occurs in extramedullary organs.


Author(s):  
Frances Moore Lappé

Not all scientific controversies are fought in the laboratory: Today much of our planet is the testing ground in a scientific controversy touching virtually every human being on Earth. It centers on the path we choose to feed ourselves, a choice that will create ripples ranging from the extent of hunger and the severity of climate change to how many species remain at century’s end. And that path will be shaped by what social philosopher Erich Fromm (1973) called a “frame of orientation”—the core assumptions, often beneath conscious awareness, through which we each view our world. For human beings, these frames function as filters, determining what we see and what we do not see. Today, two quite different ways of seeing the global food challenge are emerging as scientists, farmers, and engaged citizens struggle to answer the question: How will we feed ourselves? Here I contrast the frames, the first and dominant one—promoted in most US agricultural universities and by farm-related corporations—I call “productivist” because the frame defines the challenge of conquering today’s hunger and meeting growing demand largely as that of producing more food. Limiting the human population is also seen as critical. The second lens is my own and that of a growing number of food and farming experts worldwide. It is sometimes described as “ecological” or “sustainable.” But such terms might mislead by suggesting a worldview focusing principally, or exclusively, on the environment. So I prefer to call the lens “relational,” suggesting a way of seeing that embraces both the ecological and social dimensions of the food system. Its focus is not primarily on the quantities produced but the qualities of relationships within both human and nonhuman aspects of food systems, as it asks whether these relationships enhance life. I first present the productivist frame and then the relational. Worldwide, our “food system is working for the majority of people,” notes the UK think-tank Foresight (2011, p. 36). Yields of major food crops have grown markedly.


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