2. First responders: the innate immune response
2017 ◽
pp. 17-29
Keyword(s):
How does the immune system know when to respond? ‘First responders: the innate immune response’ considers this fundamental question that is central to understanding both normal (e.g. to infections) and abnormal (e.g. in auto-immune diseases) responses; and designing vaccines and new therapies in cancer and infectious diseases. It looks at how ‘danger’ is sensed by the immune system through pathogen-associated molecular patterns and damage-associated molecular patterns. Having been alerted, it is important that rapid action is taken to limit the spread of a pathogen. A number of responses can be initiated immediately, forming a critical part of our innate immunity, which are followed by the acute phase response.
Keyword(s):
2018 ◽
pp. 175-187
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Keyword(s):
2006 ◽
Vol 13
(2)
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pp. 219-226
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