A Primer of Drug Action: A Concise Nontechnical Guide to the Actions, Uses, and Side Effects of Psychoactive Drugs, Ninth Edition

2002 ◽  
Vol 59 (11) ◽  
pp. 1130-1131
Author(s):  
Thea R. Moore
Keyword(s):  
Side Effects ◽  
Drug Action ◽  
Psychoactive Drugs ◽  
Ninth Edition

A Comparison of Two Butyrophenones with Trifluoperazine

1966 ◽  
Vol 11 (1) ◽  
pp. 26-30 ◽  
Author(s):  
G. Marjerrison ◽  
W. Hrychuk ◽  
E.I. Varsanyi
Keyword(s):  
Side Effects ◽  
Rating Scale ◽  
Drug Action ◽  
Small Study ◽  
Clinical Effects ◽  
Double Blind ◽  
Morbidity Score ◽  
Closed Ward

A small study was carried out to compare the clinical effects of the two butyrophenone compounds, triperidol and haloanisone to those of trifluoperazine, in a population of chronically hospitalized long-term schizophrenics in a closed ward setting. Twenty-seven patients were randomly assigned to one of the three compounds, and treated for a twelve-week period under double-blind conditions. Observations with a modified PRP rating scale, based on ward nurses' monthly ratings, revealed an over-all improvement after one month of treatment, but differences between the three drugs were not apparent and the over-all decrease of this PRP morbidity score was not sustained in subsequent ratings. Psychiatrist's ratings on the IMPS revealed several symptom-factor differences with treatment. Between-drug differences on these factors were apparent. They are discussed in terms of the possible differences in type of drug action which they may reflect. The incidence of parkinsonistic side effects with each drug is presented. In no case did the side effects prevent continued treatment with the compound.

Psychoactive Drugs in Outpatient Therapy

1971 ◽  
Vol 2 (2) ◽  
pp. 116-125 ◽  
Author(s):  
Louis A. Gottschalk
Keyword(s):  
Social Class ◽  
Side Effects ◽  
Clinical Evaluation ◽  
Drug Effect ◽  
Demographic Data ◽  
Placebo Response ◽  
Psychoactive Drugs ◽  
Outpatient Therapy ◽  
Patient Responses ◽  
First Time

A great many patients coming to a clinic for the first time are already using one or more drugs. The physician must be aware of this, not only for the purpose of prescription, but also in determining the validity of patient responses. He should be aware, too, of the correlation between demographic data and drug effect. If a drug is indicated, the therapist must consider, in addition to questions of potency, side effects and possible habituation, what he hopes to achieve through therapy. This paper provides a brief clinical evaluation of psychoactive drugs and their interaction with such non-drug variables as setting, expectation, placebo response, therapist attitude, and social class.

scholarly journals Avaliação da Orientação Médica sobre Efeitos Colaterais de Fármacos Psicoativos em Usuários de um Programa de Saúde da Família de uma Cidade do Sul de Minas/Evaluation of Medical Advice about Side Effects of Psychoactive Drugs among Users of a Family Heal

1970 ◽  
Vol 2 (1) ◽  
pp. 12-19
Author(s):  
Natalia Carolina Santos e Silva ◽  
Livia Viana Trevisan ◽  
Melissa de Oliveira Gorgulho ◽  
Nilo César do Vale Baracho
Keyword(s):  
Side Effects ◽  
Key Words ◽  
Medical Advice ◽  
Psychoactive Drugs

Objetivo: Avaliar a orientação médica sobre os efeitos colaterais das drogas psicotrópicas Metodologia: Foram entrevistados 136 indivíduos adultos usuários de fármacos psicoativos, entre 18 e 100 anos, escolhidos aleatoriamente, pertencentes a um bairro de uma cidade do Sul de Minas. O questionário aplicado continha perguntas sobre dados biodemográficos, tipo de atendimento médico recebido, particularidades sobre a droga prescrita e orientações recebidas do médico. Resultados: Com relação à frequência de consultas com o médico prescritor, a maioria (38,98%) se consultava com um intervalo de seis meses ou mais. Dos entrevistados, 83,82% utilizam o fármaco de forma contínua, com uma minoria (16,18%) os utilizando de forma intermitente. Ao se analisar o tempo de uso do fármaco, 73,54% o faz por mais de um ano e 97,06% não receberam orientação quanto ao tempo de uso do medicamento. Dos pacientes que já fizeram tentativas de parar o uso (53,68%), a maioria (76,71%) utilizou a redução gradual como forma de interrupção e destes, 56,16% foi sem orientação médica e 64,38% não obtiveram sucesso. A orientação quanto ao uso de álcool foi a única informação recebida por 53,31% dos pacientes, sendo que 35,55% não recebeu nenhuma informação sobre efeitos colaterais. Conclusão: Os dados obtidos demonstram que a orientação sobre a utilização dos medicamentos psicotrópicos não está sendo feita de forma satisfatória por parte dos médicos do serviço estudado. Palavras chave: Fármacos psicoativos, efeitos colaterais, orientações médicas. Key words: Psychoactive drugs, side effects, medical advice.

Effectiveness Of Domestic Preparation Kromoviz In Treatment Of Allergic Conjunctivites

2020 ◽  
Vol 03 (06) ◽  
pp. 59-65
Author(s):  
Nuraliev Nekkadam Abdullaevich ◽  
◽  
Safarov Jakhongir Oripovich ◽  
Khasanov Mukhriddin Khayotovich ◽  
◽  
...  
Keyword(s):  
Side Effects ◽  
Economic Efficiency ◽  
Allergic Conjunctivitis ◽  
Clinical Effect ◽  
Clinical Manifestations ◽  
Maximum Level ◽  
Drug Action ◽  
Control Group ◽  
Therapeutic Result ◽  
Basic Treatment

Purpose: to study the efficacy and tolerability of the domestic drug cromoviz in the treatment of allergic conjunctivitis. The state of the organ of vision in 60 patients (120 eyes) with allergic conjunctivitis was studied. Depending on the therapy, the patients were divided into two groups of homogeneous clinical manifestations. At the same time, the patients of the main group (30 patients) were instilled with the drug Cromoviz (Uzbekistan), 2 drops 4 times a day for 4 weeks. Patients of the control group (30 patients) were instilled with Aycrol according to the same scheme. The obtained research results showed that the use of the domestic drug cromoviz against the background of basic treatment is expressed in a decrease in subjective complaints of patients and a significant clinical effect in 95.9% of cases. The revealed economic efficiency of the drug action indicates the achievement of the maximum level of therapeutic result at an acceptable price for the patient and therapeutic-prophylactic institution. Cases of side effects and intolerance to the domestic drug cromoviz were not identified in our studies.

Drugs Treatment for Deaf People

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
C. Moreno Menguiano
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Side Effects ◽  
Pharmacological Treatment ◽  
Daily Life ◽  
Psychoactive Drugs ◽  
Deaf People ◽  
Deaf Persons ◽  
The Way

The resources for deaf persons’ mental health and the studies in the field of the psychopharmacology are nowadays inadequate to meet the specific needs of this population. The indications or the way of using the medication do not differ between deaf and hearing persons, but it is not well-known among professionals that during the psychopharmacologic treatment of deaf patients it is possible to observe the presence of intense and unexpected side effects of the medication, so that it does turn out to be indispensable to give special attention to the prescription of psychoactive drugs in deaf persons. This ignorance is partly due to the fact that the research in this area is deficient. The above mentioned side effects are more prevailing and intense in deaf persons than in hearings and often interfere with basic aspects of a person's daily life as it is his system of communication, the language of signs that becomes affected, for example, due to alterations in the vision or the movement, which means in practice (at the same time) a decrease in the quality of life. Therefore, our aim is to emphasize that the indications for pharmacological treatment in deaf persons are the same than in hearings and at the same time to emphasize the importance of knowing the specific needs.

scholarly journals Educating Psychiatric Patients about their Treatment: Do Fact Sheets Work?

1996 ◽  
Vol 89 (12) ◽  
pp. 690-693 ◽  
Author(s):  
Mark Evans ◽  
Rob Macpherson ◽  
Emma Thompson ◽  
Isam Babiker
Keyword(s):  
Health Care ◽  
Side Effects ◽  
Patient Education ◽  
Health Care Professional ◽  
Psychiatric Patients ◽  
Drug Action ◽  
Fact Sheet ◽  
Subsequent Discussion ◽  
Control Knowledge ◽  
And Control

Psychiatric patients are sometimes given fact sheets about their treatment but the benefits of these are uncertain. We tested three strategies in three cohorts of psychiatric inpatients—fact sheets alone, fact sheets and subsequent discussion, and control. Knowledge of medication was assessed by questionnaire. For various reasons, only 33 of the 77 patients were included in the study or analysis. Of the patients who had been given fact sheets, 87% independently read them and reported finding them helpful whilst all asked for more information. Receiving a fact sheet alone had no significant effect, whereas having discussed it with a health care professional was associated with a significant increase in knowledge about medication. Patients receiving fact sheets selectively learned more about side-effects than about drug action or precautions. This strategy for patient education could be used by ward nurses and deserves further evaluation.

scholarly journals Psychopharmacology: From serendipitous discoveries to rationale design, but what next?

2018 ◽  
Vol 2 ◽  
pp. 239821281881262
Author(s):  
Emma Robinson
Keyword(s):  
Side Effects ◽  
Drug Development ◽  
20Th Century ◽  
Second Generation ◽  
Therapeutic Targets ◽  
Pharmaceutical Companies ◽  
Psychoactive Drugs ◽  
Subsequent Research ◽  
Clinical Observations

Psychopharmacology really developed as a discipline from the mid-20th century with the discovery of a number of new classes of psychoactive drugs which could modify behaviour. These drugs were discovered as a consequence of clinical observations of patients, often being treated for other conditions. These serendipitous discoveries were the start of an era of drug development which has led to the antidepressants, antipsychotics, anxiolytics and mood stabilisers used today. Subsequent research focused on understanding why these drugs were effective, and used this information to develop a second generation of drugs that were more selective for their therapeutic targets, and therefore had reduced side effects and improved safety and tolerability. After a period of decline in new discoveries and withdrawal of the majority of the major pharmaceutical companies from active development programmes in psychiatry, new avenues are emerging fuelling renewed interest in this area.

Hazards Implicit in Prescribing Psychoactive Drugs: Mystification in drug use and models of drug action are reviewed

Science ◽  
1970 ◽  
Vol 169 (3944) ◽  
pp. 438-441 ◽  
Author(s):  
H. L. Lennard ◽  
L. J. Epstein ◽  
D. C. Ransom ◽  
A. Bernstein
Keyword(s):  
Drug Use ◽  
Drug Action ◽  
Psychoactive Drugs
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