Culturally Sensitive Normative Data for the Color Trails Test in the Indian Population

2019 ◽  
Vol 34 (6) ◽  
pp. 856-856
Author(s):  
K Indorewalla ◽  
M Lanca ◽  
J Osher ◽  
R Kartik ◽  
N Vaidya ◽  
...  
Keyword(s):  
Educational Attainment ◽  
Normative Data ◽  
Indian Population ◽  
Community Dwelling ◽  
Culturally Appropriate ◽  
Trail Making ◽  
Neurocognitive Measures ◽  
Healthy Community ◽  
Completion Times ◽  
Better Than

Abstract Objective The Color Trails Test (CTT) is a neuropsychological measure tapping into frontal and executive functioning, while at the same time minimizing the cultural and language barriers inherent in similar neurocognitive measures such as the Trail Making Test (TMT). This study generates culturally-appropriate normative data for the CTT in an adult Indian population. Method Six-hundred and sixty-nine cognitively healthy, community dwelling Indian individuals between ages 18 and 69 participated in the study. Eligible participants were stratified on the basis of age, gender, and educational attainment. Participant performance on the CTT and TMT were correlated to establish concurrent validity. Results Significant correlations were found between TMT-part A and CTT-part 1 (r = .61) and between TMT-part B and CTT-part 2 (r = .66). In addition to generating culturally-appropriate normative data, the current study found that age and educational attainment significantly impacted participant performance on CTT-Part 1 [F(4, 649) = 4.395, p = .002], whereas gender, along with age, and educational attainment significantly impacted performance on CTT-Part 2 [F(4,649) = 2.446, p = .045]. In general, younger participants with more educational attainment performed better on both parts of the CTT. Interestingly, older female participants with lower educational attainment performed better than their younger counterparts on CTT-Part 2, whereas no such findings were noted for male participants. Conclusions Age, gender, and educational attainment are important factors to consider when interpreting CTT completion times in the Indian population. Normative data generated from this study has important clinical implications and contributes to the growing body of culturally-appropriate normative data available for the Indian population.

Late-Night Salivary Cortisol in Healthy, Community-Dwelling Asian Indians Assessed by Second-Generation ECLIA

2020 ◽  
Vol 105 (8) ◽  
pp. e2807-e2814 ◽  
Author(s):  
Nandini Prasad ◽  
Puthiyaveettil Khadar Jabbar ◽  
Chellamma Jayakumari ◽  
Mathew John ◽  
Retheesh Kollerazhikathu Haridasan ◽  
...  
Keyword(s):  
Asian Indian ◽  
Salivary Cortisol ◽  
Indian Population ◽  
Second Generation ◽  
Community Dwelling ◽  
Late Night ◽  
Upper Limit ◽  
Late Night Salivary Cortisol ◽  
Asian Indian Population ◽  
Healthy Community

Abstract Background Late-night salivary cortisol (LNSC) is used as a screening test for Cushing syndrome (CS), but there is no community-derived normative data for the normal upper limit in the South Asian population. This study aimed to determine the upper limit of normal (97.5th percentile) for LNSC in an Asian Indian population using a commercially available second-generation electrochemiluminiscence immunoassay (ECLIA). Methods LNSC in apparently healthy community-dwelling individuals was assessed by multistage cluster sampling. Healthy individuals age 18 to 60 years from 8 urban and 8 rural clusters of Thiruvananthapuram district were studied. Thirty people from an approximate population of 1000 individuals from each cluster participated in the study. A saliva sample was collected between 11 PM and 12 midnight and analyzed using Roche COBAS-e-411 and ultrasensitive Cortisol II kits the next day. Results Cortisol values from 474 salivary samples were available for final analysis after exclusion of improperly collected samples. The 97.5th percentile of the LNSC concentrations was 0.25 μg/dL (6.89 nmol/L) (90% CI, 0.23-0.27 μg/dL; ie, 6.34-7.45 nmol/L). In postmenopausal women, median LNSC was significantly higher but the 90% CI for the upper limit of their LNSC (0.28μg/dL or 7.72 nmol/L) overlapped with that of premenopausal women. Conclusions This study establishes the normal value of LNSC estimated by second-generation ECLIA in healthy community-dwelling Asian Indian individuals for the first time. Salivary cortisol at 11 pm to 12 am is less than 0.25μg/dL (6.89 nmol/L) in the general Asian Indian population. Menopause causes a significant increase in LNSC and may lead to overdiagnosis of CS if not interpreted carefully.

scholarly journals Normative Data for the Balance Error Scoring System in Adults

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Grant L. Iverson ◽  
Michael S. Koehle
Keyword(s):  
Scoring System ◽  
Normative Data ◽  
Brain Injuries ◽  
Community Dwelling ◽  
Cross Sectional ◽  
Fitness Evaluation ◽  
Cohort Design ◽  
Balance Error Scoring System ◽  
Balance Error ◽  
Better Than

Background. The balance error scoring system (BESS) is a brief, easily administered test of static balance. The purpose of this study is to develop normative data for this test.Study Design. Cross-sectional, descriptive, and cohort design.Methods. The sample was drawn from a population of clients taking part in a comprehensive preventive health screen at a multidisciplinary healthcare center. Community-dwelling adults aged 20–69 (N=1,236) were administered the BESS within the context of a fitness evaluation. They did not have significant medical, neurological, or lower extremity problems that might have an adverse effect on balance.Results. There was a significant positive correlation between BESS scores and age (r=.34). BESS performance was similar for participants between the ages of 20 and 49 and significantly declined between ages 50 and 69. Men performed slightly better than women on the BESS. Women who were overweight performed significantly more poorly on the test compared to women who were not overweight (P<.0001; Cohen'sd=.62). The BESS normative data are stratified by age and sex.Conclusions. These normative data provide a frame of reference for interpreting BESS performance in adults who sustain traumatic brain injuries and adults with diverse neurological or vestibular problems.

scholarly journals Regression-Based Normative Data for Independent and Cognitively Active Spanish Older Adults: Digit Span, Letters and Numbers, Trail Making Test and Symbol Digit Modalities Test

2021 ◽  
Vol 18 (19) ◽  
pp. 9958
Author(s):  
Clara Iñesta ◽  
Javier Oltra-Cucarella ◽  
Beatriz Bonete-López ◽  
Eva Calderón-Rubio ◽  
Esther Sitges-Maciá
Keyword(s):  
Older Adults ◽  
General Population ◽  
Neuropsychological Assessment ◽  
Normative Data ◽  
Digit Span ◽  
Base Rate ◽  
Community Dwelling ◽  
Trail Making Test ◽  
Active Population ◽  
Trail Making

In this work, we developed normative data for the neuropsychological assessment of independent and cognitively active Spanish older adults over 55 years of age. Method: Regression-based normative data were calculated from a sample of 103 non-depressed independent community-dwelling adults aged 55 or older (67% women). Raw data for Digit Span (DS), Letters and Numbers (LN), the Trail Making Test (TMT), and the Symbol Digit Modalities Test (SDMT) were regressed on age, sex, and education. The model predicting TMT-B scores also included TMT-A scores. Z-scores for the discrepancy between observed and predicted scores were used to identify low scores. The base rate of low scores for SABIEX normative data was compared to the base rate of low scores using published normative data obtained from the general population. Results: The effects of age, sex, and education varied across neuropsychological measures. Although the proportion of low scores was similar between normative datasets, there was no agreement in the identification of cognitively impaired individuals. Conclusions: Normative data obtained from the general population might not be sensitive to identify low scores in cognitively active older adults, incorrectly classifying them as cognitively normal compared to the less-active population. We provide a friendly calculator for use in neuropsychological assessment in cognitively active Spanish people aged 55 or older.

scholarly journals The de Morton Mobility Index: Normative Data for a Clinically Useful Mobility Instrument

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
E. M. Macri ◽  
J. A. Lewis ◽  
K. M. Khan ◽  
M. C. Ashe ◽  
N. A. de Morton
Keyword(s):  
Assisted Living ◽  
Independent Living ◽  
Normative Data ◽  
Health Assessment ◽  
Reference Population ◽  
Community Dwelling ◽  
Mobility Spectrum ◽  
Cross Sectional ◽  
Retirement Village ◽  
Healthy Community

Determining mobility status is an important component of any health assessment for older adults. In order for a mobility measure to be relevant and meaningful, normative data are required for comparison to a healthy reference population. The DEMMI is the first mobility instrument to measure mobility across the spectrum from bed bound to functional levels of independent mobility. In this cross-sectional observational study, normative data were obtained for the DEMMI from a population of 183 healthy, community-dwelling adults age 60+ who resided in Vancouver, Canada and Melbourne, Australia. Older age categories had significantly lower DEMMI mobility mean scores (P<0.05), as did individuals who walked with a mobility aid or lived in semi-independent living (assisted living or retirement village), whereas DEMMI scores did not differ by sex (P=0.49) or reported falls history (P=0.21). Normative data for the DEMMI mobility instrument provides vital reference scores to facilitate its use across the mobility spectrum in clinical, research, and policymaking settings.

Penjadwalan Mesin dengan Metode Integer Linear Programming pada PT. XYZ

2019 ◽  
Vol 2 (2) ◽  
Author(s):  
Fransiskus Lauson Matondang ◽  
Rosnani Ginting
Keyword(s):  
Integer Programming ◽  
Time Delays ◽  
Parallel Machines ◽  
Research Concept ◽  
Total Settlement ◽  
Approach Method ◽  
Additional Costs ◽  
Maximum Completion Time ◽  
Completion Times ◽  
Better Than

PT XYZ sering mengalami keterlambatan waktu karena dalam setiap keterlambatan yang dilakukan selalu ada penalty yang diberikan kepada perusahaan dan hal ini mengakibatkan tambahan biaya , oleh karena itu hal ini harus dihindari dengan membuat penjadwalan yang efisien, dalam hal ini dilakukanlah perbaikan dengan meminimisasi waktu penyelesaian maksimum Cmax pada mesin paralel yang berpola aliran flowshop (dan tidak boleh dilakukan interupsi yang dilakukan pada pekerjaan yang sedang diproses, untuk melakukan pekerjaan lainnya, satu lintasan hanya memproduksi satu produk dan hanya satu produk juga yang dikerjakan secara langsung. Waktu penyelesaian yang berbeda dari setiap mesin dengan pengerjaannya juga adalah masalah yang dihadapi untuk menjadikan mesin mesin ini sesuai menjadi satu penjadwalan yang terintegrasi dengan metode integer programming yang membuat penjadwalan dengan konsep riset operasi dengan metode pendekatan 0-1 utuk menjadi lebih efisien lagi , dihasilkan minimisasi keterlambatan total penyelesaian order dengan 42,28 menit lebih baik dari sebelumnya.   PT XYZ often experiences time delays because in every delay made there is always a penalty given to the company and this results in additional costs, therefore this must be avoided by making efficient scheduling, in this case repairs are carried out by minimizing the maximum completion time of Cmax on parallel machines that are patterned with flowshop flow (and no interruptions should be carried out on the work being processed, to do other work, one track only produces one product and only one product is directly worked. Different completion times of each machine with the workmanship is also the problem faced to make this machine suitable to be one scheduling integrated with integer programming methods that makes scheduling with the operational research concept with the 0-1 approach method to be more efficient, resulting in minimization of the delay in the total settlement of orders with 42.28 minutes was better than before.

Factors Associated with Lower Cognitive Performance Scores Among Older Japanese Men in Hawaii and Japan

2021 ◽  
pp. 1-10
Author(s):  
Naoko Miyagawa ◽  
Takayoshi Ohkubo ◽  
Akira Fujiyoshi ◽  
Akihiko Shiino ◽  
Randi Chen ◽  
...  
Keyword(s):  
Educational Attainment ◽  
Cognitive Abilities ◽  
Subclinical Atherosclerosis ◽  
Lifestyle Factors ◽  
Community Dwelling ◽  
Multivariable Logistic Regression Analysis ◽  
Cross Sectional ◽  
Japanese Men ◽  
History Of ◽  
Cardiometabolic Factors

Background: Few studies have compared factors related to cognitive function among people with similar genetic backgrounds but different lifestyles. Objective: We aimed to identify factors related to lower cognitive scores among older Japanese men in two genetically similar cohorts exposed to different lifestyle factors. Methods: This cross-sectional study of community-dwelling Japanese men aged 71–81 years included 2,628 men enrolled in the Kuakini Honolulu-Asia Aging Study based in Hawaii and 349 men in the Shiga Epidemiological Study of Subclinical Atherosclerosis based in Japan. We compared participant performance through Cognitive Abilities Screening Instrument (CASI) assessment in Hawaii (1991–1993) and Japan (2009–2014). Factors related to low cognitive scores (history of cardiovascular disease, cardiometabolic factors, and lifestyle factors) were identified with questionnaires and measurements. Multivariable logistic regression analysis was used to calculate the adjusted odds ratios (ORs) of a low (<  82) CASI score based on different factors. Results: CASI scores were lower in Hawaii than in Japan [21.2%(n = 556) versus 12.3%(n = 43), p <  0.001], though this was not significant when adjusted for age and educational attainment (Hawaii 20.3%versus Japan 17.9%, p = 0.328). History of stroke (OR = 1.65, 95%confidence interval = 1.19–2.29) was positively associated with low cognitive scores in Hawaii. Body mass index ≥25 kg/m2 tended to be associated with low cognitive scores in Japan; there was a significant interaction between the cohorts. Conclusion: Cognitive scores differences between cohorts were mostly explained by differences in educational attainment. Conversely, cardiovascular diseases and cardiometabolic factors differentially impacted cognitive scores among genetically similar older men exposed to different lifestyle factors.

Alcohol Drinking and Brain Morphometry in Apparently Healthy Community-Dwelling Japanese Men

Alcohol ◽  
2020 ◽  
Author(s):  
Ali Haidar Syaifullah ◽  
Akihiko Shiino ◽  
Akira Fujiyoshi ◽  
Aya Kadota ◽  
Keiko Kondo ◽  
...  
Keyword(s):  
Alcohol Drinking ◽  
Community Dwelling ◽  
Japanese Men ◽  
Brain Morphometry ◽  
Healthy Community ◽  
Apparently Healthy

Normative Data for Raven's Coloured Progressive Matrices Scale in Yemen

2008 ◽  
Vol 103 (1) ◽  
pp. 170-172
Author(s):  
Omar Khaleefa ◽  
Richard Lynn
Keyword(s):  
Sex Difference ◽  
Normative Data ◽  
Older Children ◽  
Standardization Sample ◽  
Better Than

Results are reported for a standardization sample of 986 6- to 11-yr.-olds for the Coloured Progressive Matrices in Yemen. Younger children performed better than older children relative to British norms, and there was no significant sex difference in means or variability. In relation to a British IQ of 100 ( SD=15), the sample obtained an average IQ of approximately 81.

A-11 Investigating Gene–Gene Interactions by Cognitive Domain in Healthy Older Adults

2021 ◽  
Vol 36 (6) ◽  
pp. 1051-1051
Author(s):  
Kendra L Pizzonia ◽  
Andrew M Bryant ◽  
Leatha A Clark ◽  
Brian C Clark ◽  
Julie A Suhr
Keyword(s):  
Executive Functioning ◽  
Cognitive Functioning ◽  
Verbal Fluency ◽  
Community Dwelling ◽  
Gene Interactions ◽  
Trail Making Test ◽  
Semantic Fluency ◽  
Immediate Memory ◽  
Trail Making ◽  
Main Effects

Abstract Objective ApoE is a well-known gene carrying risk for Alzheimer’s disease and is associated with memory performance while the COMT gene is associated with executive functioning but is understudied. The present study investigated these gene interactions across cognitive domains. Method A larger study on gait and aging recruited 89 healthy community-dwelling adults over the age of 60. The primary analyses included 82 participants (67% female, mean age = 74.61, SD = 6.71). The analyses on executive functioning included 72 participants (65% female, mean age = 73.02, SD = 4.99) who completed all measures of interest. ApoE status was defined as presence/absence of Ɛ4. The rs4680 gene on the COMT allele was classified into Val/Met, Val/Val, and Met/Met genotypes. Biological sex was included as a binary term (i.e., male/female). Index variables and age corrected standard scores on the Repeatable Battery for the Assessment of Neuropsychological Status, verbal fluency, and Trail Making Test were included. Results Gene–gene interactions were found for overall cognitive functioning, immediate memory, and semantic fluency. There were main effects of sex for overall cognitive functioning, immediate memory, delayed memory, and semantic fluency. There were main effects for COMT for delayed memory and a main effect for both COMT and ApoE for visuospatial functioning, coding, and verbal fluency (all p’s &lt; 0.05). There were no ApoE x COMT x Sex interactions and Trail Making Test B was not related to either gene or sex. Conclusion(s) Our findings suggest that both COMT and ApoE (and their interaction) influence cognition. Future research should investigate gene–gene interactions in larger samples with more comprehensive cognitive batteries.

A Decade of Decline in Serious Cognitive Problems Among Older Americans: A Population-Based Study of 5.4 Million Respondents

2021 ◽  
pp. 1-11
Author(s):  
Esme Fuller-Thomson ◽  
Katherine Marie Ahlin
Keyword(s):  
Educational Attainment ◽  
Generational Differences ◽  
Temporal Trends ◽  
Secondary Analysis ◽  
Population Based ◽  
Community Dwelling ◽  
Older Americans ◽  
Age Cohort ◽  
Nationally Representative ◽  
Cognitive Problems

Background: Numerous studies suggest the prevalence of dementia has decreased over the past several decades in Western countries. Less is known about whether these trends differ by gender or age cohort, and if generational differences in educational attainment explain these trajectories. Objective: 1) To detect temporal trends in the age-sex-race adjusted prevalence of serious cognitive problems among Americans aged 65+; 2) To establish if these temporal trends differ by gender and age cohort; 3) To examine if these temporal trends are attenuated by generational differences in educational attainment. Methods: Secondary analysis of 10 years of annual nationally representative data from the American Community Survey with 5.4 million community-dwelling and institutionalized older adults aged 65+. The question on serious cognitive problems was, “Because of a physical, mental, or emotional condition, does this person have serious difficulty concentrating, remembering, or making decisions?” Results: The prevalence of serious cognitive problems in the US population aged 65 and older declined from 12.2%to 10.0%between 2008 and 2017. Had the prevalence remained at the 2008 levels, there would have been an additional 1.13 million older Americans with serious cognitive problems in 2017. The decline in memory problems across the decade was higher for women (23%) than for men (13%). Adjusting for education substantially attenuated the decline. Conclusion: Between 2008 and 2017, the prevalence of serious cognitive impairment among older Americans declined significantly, although these declines were partially attributable to generational differences in educational attainment.

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