scholarly journals Anthropometry and C-reactive Protein and Clinical Outcomes in Children with Cancer in Intensive Care Unit (P12-023-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Wanelia Afonso ◽  
Wilza Peres ◽  
Nivaldo Pinho ◽  
Renata Martucci ◽  
Carolina Soares ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Clinical Outcomes ◽  
Body Mass ◽  
Nutritional Assessment ◽  
Treatment Center ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Funding Sources

Abstract Objectives To evaluate the influence of nutritional status on admission, according to the anthropometric indicator (Body Mass Index- BMI), serum C-reactive protein (CRP) and albumin on length of hospital stay (LHS) and time of mechanical ventilation (MV) in the Pediatric Intensive Care Unit (PICU) in a Oncological Treatment Center. Methods It is a longitudinal retrospective study with all children admitted to the PICU in 2013. The comparison of medians related to LHS and VM was assessed using the nonparametric Mann-Whitney and Kruskal Wallis test. The Kaplan-Meier curve evaluated the influence of body mass index (BMI), CRP and albumin on LHS and VM. The significance value was P < 0.05. Results A total of 54 patients were selected, median age of 8.02 (2.35–12.79) years. Solid tumors were the most common (92.6%; n = 50), and the most frequent causes of hospitalization in the PICU were respiratory failure (26.4%; n = 14) and sepsis (24.5%; n = 13). The median LHS was 11 (6–18) days and MV median was 11 (6–16.86) days. The frequency of BMI above and below the adequate level was 23.5% (n = 12) and 29.4% (n = 15), respectively. Conclusions BMI and CRP used for nutritional assessment were not associated with clinical outcomes LHS and MV in PICU. Funding Sources No funding sources.

scholarly journals A espessura do músculo adutor do polegar não está associada a Proteína C Reativa em pacientes com câncer hospitalizados

2021 ◽  
Vol 4 (35) ◽  
pp. 340-344
Author(s):  
Nathália da Cunha Ferré ◽  
Rebeca Palhares Barbosa ◽  
Thaís Cristina Borges ◽  
Gustavo Duarte Pimentel
Keyword(s):  
Body Mass Index ◽  
Logistic Regression ◽  
Body Mass ◽  
Nutritional Assessment ◽  
Muscle Thickness ◽  
Adductor Pollicis ◽  
C Reactive Protein ◽  
Cross Sectional ◽  
Adductor Pollicis Muscle ◽  
Reactive Protein

Objective: To evaluate the association between blood of C-reactive protein concentrations and an indicator of muscle mass in hospitalized cancer patients. Methods: A cross-sectional study carried out with 110 patients of both sexes, aged ≥18 years, with solid and/or liquid cancer undergoing clinical and/or surgical treatment. Clinical and socioeconomic data were obtained from medical records. The adductor pollicis muscle thickness was obtained using skinfold caliper. Patients were divided into two groups: altered adductor pollicis muscle thickness (<13.4 mm) and normal adductor pollicis muscle thickness (≥13.4 mm). Logistic regression was performed to verify the association between adductor pollicis muscle thickness and C-reactive protein. Results: It was observed that 90% (n = 100) of the patients were classified with reduced adductor pollicis muscle thickness, higher prevalence of the solid tumor, low usual weight, current weight, and body mass index. The logistic regression analysis showed no association between the adductor pollicis muscle thickness and C-reactive protein concentrations, in any of models used: model without adjustment (OR: 1.01; 95% CI [0.94-1.09], p = 0.65); adjusted for sex and age (OR: 1.01; 95% CI [0.94-1.09], p = 0.61); and adjusted model for sex, age and body mass index (BMI) (OR: 1.04; 95% CI [0.96-1.13], p = 0.29). Conclusion: Although adductor pollicis muscle thickness is validated method for nutritional assessment, we did not find an association with the inflammation marker (C-reactive protein).

Body Mass Index, but Not Physical Activity, Is Associated with C-Reactive Protein

2003 ◽  
Vol 35 (7) ◽  
pp. 1160-1166 ◽  
Author(s):  
ERIC S. RAWSON ◽  
PATTY S. FREEDSON ◽  
STAVROULA K. OSGANIAN ◽  
CHARLES E. MATTHEWS ◽  
GEORGE REED ◽  
...  
Keyword(s):  
Physical Activity ◽  
Body Mass Index ◽  
Body Mass ◽  
C Reactive Protein ◽  
Reactive Protein

Serum C reactive protein levels and genetic variation in the CRP gene are not associated with the prevalence, incidence or progression of osteoarthritis independent of body mass index

2010 ◽  
Vol 69 (11) ◽  
pp. 1976-1982 ◽  
Author(s):  
Hanneke J M Kerkhof ◽  
Sita M A Bierma-Zeinstra ◽  
Martha C Castano-Betancourt ◽  
Moniek P de Maat ◽  
Albert Hofman ◽  
...  
Keyword(s):  
Systematic Review ◽  
Body Mass Index ◽  
Genetic Variation ◽  
Body Mass ◽  
Analysis Of Covariance ◽  
C Reactive Protein ◽  
Knee Oa ◽  
Reactive Protein ◽  
Serum Crp ◽  
The Relationship

ObjectiveTo study the relationship between serum C reactive protein (CRP) levels, genetic variation in the CRP gene and the prevalence, incidence and progression of radiographic osteoarthritis (ROA) in the Rotterdam Study-I (RS-I). A systematic review of studies assessing the relationship between osteoarthritis (OA) and CRP levels was also performed.MethodsThe association between CRP levels and genetic variation in the CRP gene and ROA was examined in 861 patients with hand OA, 718 with knee OA, 349 with hip OA and 2806 controls in the RS-I using one-way analysis of covariance and logistic regression, respectively. PubMed was searched for articles published between January 1992 and August 2009 assessing the relationship between CRP levels and OA.ResultsIn RS-I the prevalence of knee OA, but not hip OA or hand OA, was associated with 14% higher serum CRP levels compared with controls (p=0.001). This association disappeared after adjustment for age and especially body mass index (BMI) (p=0.33). Genetic variation of the CRP gene was not consistently associated with the prevalence, incidence or progression of OA within RS-I. The systematic review included 18 studies (including RS-I) on serum CRP levels and the prevalence, incidence or progression of OA. Consistently higher crude CRP levels were found in cases of prevalent knee OA compared with controls. No association was observed between serum CRP levels and the prevalence of knee OA following adjustment for BMI (n=3 studies, meta-analysis p value=0.61).ConclusionThere is no evidence of association between serum CRP levels or genetic variation in the CRP gene with the prevalence, incidence or progression of OA independent of BMI.

C-reactive Protein, Body Mass Index, and Diabetic Retinopathy

2010 ◽  
Vol 51 (9) ◽  
pp. 4458 ◽  
Author(s):  
Laurence Shen Lim ◽  
E. Shyong Tai ◽  
Paul Mitchell ◽  
Jie Jin Wang ◽  
Wan Ting Tay ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Diabetic Retinopathy ◽  
Body Mass ◽  
Protein Body ◽  
C Reactive Protein ◽  
Reactive Protein

scholarly journals The Metabolic Phenotype of Prader-Willi Syndrome (PWS) in Childhood: Heightened Insulin Sensitivity Relative to Body Mass Index

2011 ◽  
Vol 96 (1) ◽  
pp. E225-E232 ◽  
Author(s):  
Andrea M. Haqq ◽  
Michael J. Muehlbauer ◽  
Christopher B. Newgard ◽  
Steven Grambow ◽  
Michael Freemark
Keyword(s):  
Body Mass Index ◽  
Insulin Sensitivity ◽  
Body Mass ◽  
Density Lipoprotein ◽  
High Sensitivity ◽  
Metabolic Phenotype ◽  
Prader Willi Syndrome ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Total Adiponectin

Context: Insulin sensitivity is higher in patients with Prader-Willi syndrome (PWS) than in body mass index-matched obese controls (OCs). Factors contributing to the heightened insulin sensitivity of PWS remain obscure. We compared the fasting levels of various hormones, cytokines, lipids, and liver function tests in 14 PWS patients and 14 OCs with those in 14 age- and gender-matched lean children (LC). We hypothesized that metabolic profiles of children with PWS are comparable with those of LC, but different from those of OCs. Results: Leptin levels were comparable in PWS patients and OCs, suggesting comparable degrees of adiposity. Glucose levels were comparable among groups. However, fasting insulin concentrations and homeostasis model assessment insulin resistance index were lower in PWS patients than in OCs (P &lt; 0.05) and similar to LC. Moreover, high-density lipoprotein levels were lower and triglycerides higher in OCs (P &lt; 0.05) but not PWS patients. Total adiponectin, high-molecular-weight (HMW) adiponectin and the HMW to total adiponectin ratio were higher in PWS patients (P &lt; 0.05) than in OCs and similar to LC. High-sensitivity C-reactive protein and IL-6 levels were higher in OCs than in PWS patients or LC (P &lt; 0.05). Nevertheless, PAI-1 levels were elevated in both OC and PWS patients. There were no group differences in glucagon-like peptide-1, macrophage chemoattractant protein-1, TNFα, IL-2, IL-8, IL-10, IL-12p40, IL-18, resistin, total or low-density lipoprotein cholesterol, aspartate aminotransferase, or alanine aminotransferase. Conclusions: The heightened insulin sensitivity of PWS patients relative to OCs is associated with higher levels of adiponectin and lower levels of high-sensitivity C-reactive protein and IL-6. Future studies will determine whether PWS children are protected from obesity comorbidities such as type 2 diabetes, hyperlipidemia, and nonalcoholic fatty liver disease.

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