scholarly journals Novel Coronavirus Disease 2019 (COVID-19) Pneumonia Progression Course in 17 Discharged Patients: Comparison of Clinical and Thin-Section Computed Tomography Features During Recovery

2020 ◽  
Vol 71 (15) ◽  
pp. 723-731 ◽  
Author(s):  
Xiaoyu Han ◽  
Yukun Cao ◽  
Nanchuan Jiang ◽  
Yan Chen ◽  
Osamah Alwalid ◽  
...  

Abstract Background Our objective was to retrospectively analyze the evolution of clinical features and thin-section computed tomography (CT) imaging of novel coronavirus disease 2019 (COVID-19) pneumonia in 17 discharged patients. Methods Serial thin-section CT scans of 17 discharged patients with COVID-19 were obtained during recovery. Longitudinal changes of clinical parameters and a CT pattern were documented in all patients during the 4 weeks after admission. A CT score was used to evaluate the extent of the disease. Results There were marked improvements of fever, lymphocyte counts, C-reactive proteins, and erythrocyte sedimentation rates within the first 2 weeks after admission. However, the mean CT score rapidly increased from the first to the third week, with a top score of 8.2 obtained in the second week. During the first week, the main CT pattern was ground-glass opacities (GGO; 76.5%). The frequency of GGO (52.9%) decreased in the second week. Consolidation and mixed patterns (47.0%) were noted in the second week. Thereafter, consolidations generally dissipated into GGO, and the frequency of GGO increased in the third week (76.5%) and fourth week (71.4%). Opacities were mainly located in the peripheral (76.5%) and subpleural (47.1%) zones of the lungs; they presented as focal (35.3%) or multifocal (29.4%) in the first week and became more diffuse in the second (47.1%) and third weeks (58.8%), then showed a reduced extent in fourth week (50%). Conclusions The progression course of the CT pattern was later than the progression of the clinical parameters within the first 2 weeks after admission; however, there were synchronized improvements in both the clinical and radiologic features in the fourth week.

2021 ◽  
Vol 8 (4) ◽  
pp. 594
Author(s):  
Vikram Aglave ◽  
Shashank Nagendra ◽  
Pawan T. Ojha ◽  
Kamlesh A. Jagiasi ◽  
Sumit Kharat ◽  
...  

Takayasu arteritis is an uncommon inflammatory disease of vessels that preferentially affects the aorta and its major branches. It can be a potential cause of stroke in young adults. Current study included 7 patients aged between 18 to 48 years. Each patient had varying presentations of stroke with Takayasu’s arteritis along with other neurological symptoms. Four of the 7 patients presented with ischemic strokes, one with hemorrhagic stroke, one with TIAs and one with syncopal attacks. All the patients had elevated erythrocyte sedimentation rates. Five of the seven patients were treated with steroids and methotrexate. Two were treated with azathioprine and steroids. Antiplatelets were given for those patients who had strokes and TIAs. Our cases demonstrate that Takayasu arteritis can present with varying presentations including stroke. Thus, it is important to consider Takayasu’s arteritis as an unusual etiology of stroke especially in young adults.


1959 ◽  
Vol 196 (3) ◽  
pp. 473-477 ◽  
Author(s):  
Roy L. Swank

The effect of large butter-fat meals on the blood of rabbits and dogs has been studied. Marked distortion of the red blood cells with adhesiveness and aggregation was observed. This was accompanied by slowing of the circulation and by changes in the surface tension of the plasma. In addition changes in the platelet counts, white blood counts, hematocrit and erythrocyte sedimentation rates were observed. Changes were also noted in the buffy coat, in the clotting time and in the nature of the clot.


1976 ◽  
Vol 10 (1) ◽  
pp. 39-46 ◽  
Author(s):  
G. W. Tribe ◽  
A. E. Welburn

2 batches of baboon infected with tuberculosis were subjected to serial tests with human and bovine tuberculin, while erythrocyte sedimentation rates were estimated concurrently. In the very early stages most but not all reacted to human tuberculin while fewer responded to bovine material. After further development of the disease, tuberculin tests remained positive while sedimentation rates were raised by 10-30 mm per hour. By the time early spread had occurred response to tuberculin was absent but sedimentation rates tended to increase. Advanced cases were always tuberculin negative but sedimentation rates were in excess of 50 mm per hour. Such animals were always in good physical condition and represented an insidious danger to other animals and staff in contact with them. Clinical examination failed to reveal cases of tuberculosis except in the terminal stages and no cases were diagnosed by radiography. 2 animals died from apparent anaphylaxis following inoculation of both types of tuberculin. Results showed that use of one or other of these tests alone would not have made possible the elimination of infection.


1973 ◽  
Vol 51 (9) ◽  
pp. 685-690 ◽  
Author(s):  
R. N. O'Brien ◽  
M. B. Hocking ◽  
P. McOrmond ◽  
K. R. Thornton

The rates of erythrocyte settling have been investigated in round and square cross-section tubes, vertically; and at nine different angles; and with the square tubes flat and on edge, to a minimum of 15° from the horizontal. Apparent settling rates increased as the angle from the horizontal decreased. Real settling rates (vertical settling rates) increased sharply on decreasing the angle from the horizontal, to a maximum at about 60°, and then decreased less abruptly for the shallower angles. The cross-sectional shape of the tube did not significantly affect the settling rates of erythrocytes. Settling in inclined tubes proceeds fast enough to permit clinical erythrocyte settling rate (E.S.R.) tests to be carried out in 10 min in place of the usual 60 min. If the standard E.S.R. test rack deviates as little as 5° from the vertical it can cause the observed settling rates to double relative to readings obtained on a vertical rack.


Sign in / Sign up

Export Citation Format

Share Document