scholarly journals Maternal and Neonatal Outcomes of Pregnant Women With Coronavirus Disease 2019 (COVID-19) Pneumonia: A Case-Control Study

2020 ◽  
Vol 71 (16) ◽  
pp. 2035-2041 ◽  
Author(s):  
Na Li ◽  
Lefei Han ◽  
Min Peng ◽  
Yuxia Lv ◽  
Yin Ouyang ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Cesarean Delivery ◽  
Respiratory Symptoms ◽  
Case Control Study ◽  
Case Control ◽  
Neonatal Outcomes ◽  
Control Group ◽  
Neonatal Complications ◽  
Maternal And Neonatal Outcomes ◽  
Control Study

Abstract Background The ongoing pandemic of coronavirus disease 2019 (COVID-19) has caused serious concerns about its potential adverse effects on pregnancy. There are limited data on maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia. Methods We conducted a case-control study to compare clinical characteristics and maternal and neonatal outcomes of pregnant women with and without COVID-19 pneumonia. Results During the period 24 January–29 February 2020, there were 16 pregnant women with confirmed COVID-19 pneumonia and 18 suspected cases who were admitted to labor in the third trimester. Two had vaginal delivery and the rest were cesarean delivery. Few patients presented respiratory symptoms (fever and cough) on admission, but most had typical chest computed tomographic images of COVID-19 pneumonia. Compared to the controls, patients with COVID-19 pneumonia had lower counts of white blood cells (WBCs), neutrophils, C-reactive protein (CRP), and alanine aminotransferase on admission. Increased levels of WBCs, neutrophils, eosinophils, and CRP were found in postpartum blood tests of pneumonia patients. Three (18.8%) of the mothers with confirmed COVID-19 pneumonia and 3 (16.7%) with suspected COVID-19 pneumonia had preterm delivery due to maternal complications, which were significantly higher than in the control group. None experienced respiratory failure during their hospital stay. COVID-19 infection was not found in the newborns, and none developed severe neonatal complications. Conclusions Severe maternal and neonatal complications were not observed in pregnant women with COVID-19 pneumonia who had vaginal or cesarean delivery. Mild respiratory symptoms of pregnant women with COVID-19 pneumonia highlight the need of effective screening on admission.

scholarly journals Maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia: a case-control study

2020 ◽  
Author(s):  
Na Li ◽  
Lefei Han ◽  
Min Peng ◽  
Yuxia Lv ◽  
Yin Ouyang ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Vaginal Delivery ◽  
Respiratory Symptoms ◽  
Case Control Study ◽  
Case Control ◽  
Neonatal Outcomes ◽  
Control Group ◽  
Neonatal Complications ◽  
Maternal And Neonatal Outcomes ◽  
Control Study

AbstractBackgroundThe ongoing epidemics of coronavirus disease 2019 (COVID-19) have caused serious concerns about its potential adverse effects on pregnancy. There are limited data on maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia.MethodsWe conducted a case-control study to compare clinical characteristics, maternal and neonatal outcomes of pregnant women with and without COVID-19 pneumonia.ResultsDuring January 24 to February 29, 2020, there were sixteen pregnant women with confirmed COVID-19 pneumonia and eighteen suspected cases who were admitted to labor in the third trimester. Two had vaginal delivery and the rest took cesarean section. Few patients presented respiratory symptoms (fever and cough) on admission, but most had typical chest CT images of COVID-19 pneumonia. Compared to the controls, COVID-19 pneumonia patients had lower counts of white blood cells (WBC), neutrophils, C-reactive protein (CRP), and alanine aminotransferase (ALT) on admission. Increased levels of WBC, neutrophils, eosinophils, and CRP were found in postpartum blood tests of pneumonia patients. There were three (18.8%) and two (10.5%) of the mothers with confirmed or suspected COVID-19 pneumonia had preterm delivery due to maternal complications, which were significantly higher than the control group. None experienced respiratory failure during hospital stay. COVID-19 infection was not found in the newborns and none developed severe neonatal complications.ConclusionSevere maternal and neonatal complications were not observed in pregnant women with COVID-19 pneumonia who had vaginal delivery or caesarean section. Mild respiratory symptoms of pregnant women with COVID-19 pneumonia highlight the need of effective screening on admission.

scholarly journals Obstetric, maternal, and neonatal outcomes in COVID-19 compared to healthy pregnant women in Iran: a retrospective, case-control study

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Seyed-Abdolvahab Taghavi ◽  
Solmaz Heidari ◽  
Shayesteh Jahanfar ◽  
Shakiba Amirjani ◽  
Amireh Aji-ramkani ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Incidence Rate ◽  
Preterm Labor ◽  
Case Control Study ◽  
Case Control ◽  
Neonatal Outcomes ◽  
Obstetric Outcomes ◽  
Premature Delivery ◽  
Maternal And Neonatal Outcomes ◽  
Control Study

Abstract Background The purpose of the present study was to evaluate obstetric, maternal, and neonatal outcomes in COVID-19 compared to healthy pregnant women in Iran. Results A case-control study was conducted on 55 COVID-19 as the case and 55 matched control pregnant women in Hormozgan, Iran. Patients were considered to be cases if they had a positive COVID-19 test plus a positive chest X-ray result. Our measures were COVID-19 symptoms, including laboratory evaluations, clinical symptoms, and maternal and neonatal outcomes. The most prevalent symptoms related to COVID-19 were fever (69.09%) and cough (58.18%). Less common symptoms included fatigue, diarrhea, shortness of breath, sore throat, and myalgia. Hydroxychloroquine/chloroquine (58.18%) and antibiotic therapy (45.45%) were the most prevalent management in COVID-19 patients. Based on our findings, maternal and obstetric outcomes—neonatal in case groups—such as mode of delivery, premature rupture of membrane, postpartum hemorrhage, perineal resection rate, neonates’ birth weight, Apgar score, and neonatal asphyxia rate were similar to pregnant women without COVID-19. We observed a higher incidence rate of premature delivery in COVID-19 cases (25 vs. 10%) (p < 0.05). In the present study, we found that women with COVID-19 had a more than twofold increased odds of preterm labor. History of preterm delivery was also associated with high twofold odds of preterm labor. Conclusion We observed a higher incidence rate of premature delivery in COVID-19 cases. Women with COVID-19 had a more than twofold increased odds of preterm labor. Considering prematurity has high morbidity and is regarded as the primary cause of mortality in children under 5 years old, more case-control studies are needed to ascertain the results.

scholarly journals Association between Birth Plan Use and Maternal and Neonatal Outcomes in Southern Spain: A Case-Control Study

2021 ◽  
Vol 18 (2) ◽  
pp. 456
Author(s):  
Pedro Hidalgo-Lopezosa ◽  
Ana María Cubero-Luna ◽  
Andrea Jiménez-Ruz ◽  
María Hidalgo-Maestre ◽  
María Aurora Rodríguez-Borrego ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Case Control Study ◽  
Neonatal Resuscitation ◽  
Case Control ◽  
Neonatal Outcomes ◽  
Southern Spain ◽  
Retrospective Case ◽  
Apgar Scores ◽  
Primiparous Women ◽  
Control Study

Background: Birth plans are used for pregnant women to express their wishes and expectations about childbirth. The aim of this study was to compare obstetric and neonatal outcomes between women with and without birth plans. Methods: A multicentre, retrospective case–control study at tertiary hospitals in southern Spain between 2009 and 2013 was conducted. A total of 457 pregnant women were included, 178 with and 279 without birth plans. Women with low-risk gestation, at full-term and having been in labour were included. Sociodemographic, obstetric and neonatal variables were analysed and comparisons were established. Results: Women with birth plans were older, more educated and more commonly primiparous. Caesarean sections were less common in primiparous women with birth plans (18% vs. 29%, p = 0.027); however, no significant differences were found in instrumented births, 3rd–4th-degree tears or episiotomy rates. Newborns of primiparous women with birth plans obtained better results on 1 min Apgar scores, umbilical cord pH and advanced neonatal resuscitation. No significant differences were found on 5 min Apgar scores or other variables for multiparous women. Conclusions: Birth plans were related to less intervention, a more natural process of birth and better outcomes for mothers and newborns. Birth plans can improve the welfare of the mother and newborn, leading to birth in a more natural way.

Maternal and neonatal outcomes of abnormal placentation: a case–control study

2020 ◽  
pp. 1-7 ◽  
Author(s):  
Roksana Moeini ◽  
Hossein Dalili ◽  
Zeinab Kavyani ◽  
Mamak Shariat ◽  
Hasti Charousaei ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Neonatal Outcomes ◽  
Abnormal Placentation ◽  
Maternal And Neonatal Outcomes ◽  
Control Study

Pregnancy outcomes in adolescents: a case-control study in the West of Iran

2021 ◽  
Vol 17 ◽  
Author(s):  
Salman Khazaei ◽  
Saeid Bashirian ◽  
Akram Bathaei ◽  
Mohadese Sadri ◽  
Fateme Shirani ◽  
...  
Keyword(s):  
Prenatal Care ◽  
Pregnant Women ◽  
Adolescent Pregnancy ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Adult Women ◽  
The West ◽  
Adolescent Women ◽  
Control Study

Background: Adolescent pregnancy, pregnancy in women aged between 13-19 years, is considered a major health problem. Objective: This study was performed to determine the maternal, perinatal, and neonatal outcomes of adolescent pregnancies. Materials and Methods: The present hospital-based case-control study was performed on pregnant women who were referred to Fatemieh Hospital in Hamadan City for delivery. The case group was pregnant women whose gestational age was less than 19 years (adolescent pregnancy) and the control group included pregnant women whose gestational age was at 19-35 years (adult women pregnancy). Data were analyzed using Stata software version 14. The significant level was considered less than 0.05. Results: The unwanted pregnancy was significantly higher in adolescent women (45% vs. 28.5%, P=0.002). 18% of adolescent women had the experience of spouse violence compared to 4.25% in the control group (P<0.001). Accessing prenatal care and supplements were significantly higher in adult women (P<0.05). The adult mothers had significantly higher cesarean section delivery compared adolescent group (54.91% vs. 33%, P<0.001). Also, there was a significant association between postpartum hemorrhages and the study group (22% in cases compared to 13.75% in the control group, P=0.04). The Apgar score 1 minute was significantly higher in adult mothers (8.05±2.08 vs. 7.39±2.05, P<0.001). Conclusion: In conclusion, adolescent mothers in the west of Iran had a higher risk of inadequate prenatal care, low Apgar score and postpartum hemorrhage. Therefore, society should focus on public health policies that can improve the adequacy of prenatal care among adolescents.

scholarly journals Urinary Tract Infections and Preeclampsia among Pregnant Women Attending Two Hospitals in Mwanza City, Tanzania: A 1:2 Matched Case-Control Study

2019 ◽  
Vol 2019 ◽  
pp. 1-8
Author(s):  
Joshua Kaduma ◽  
Jeremiah Seni ◽  
Clotilda Chuma ◽  
Richard Kirita ◽  
Fridolin Mujuni ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Pregnant Women ◽  
Case Control Study ◽  
Case Control ◽  
Neonatal Outcomes ◽  
Significant Bacteriuria ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

Urinary tract infection (UTI) and preeclampsia are common among pregnant women and are associated with adverse maternal-fetal and neonatal outcomes. Despite this, limited information exists on the association between UTIs and preeclampsia in Tanzania to guide specific management and thereby averting the adverse outcomes. A 1:2 matched case-control study (by age and gravidity) involving 131 pregnant women with preeclampsia (cases) and 262 without preeclampsia (controls) was conducted. Sociodemographic and clinical information was collected using a questionnaire. Midstream urine samples were collected during admission for culture and antimicrobial susceptibility testing (AST). Out of 393 pregnant women enrolled, 110 (28.0%), 95% CI: 23.8%-32.7%, had significant bacteriuria [cases: 50.4% (66/131) and control: 16.8% (44/262)]. Pregnant women with preeclampsia had 7.7 odds of having significant bacteriuria than those without preeclampsia [OR=7.7, 95% CI (4.11-14.49); p-value <0.001]. Escherichia coli, 50 (45.5%), and Klebsiella spp., 25 (23.6%), predominated, and resistance to gentamicin, ceftriaxone, and piperacillin-tazobactam ranged from 9.0% to 29.0% in these dominant species. Extended spectrum beta lactamases (ESBL) production in Escherichia coli and Klebsiella spp. was 18.0% (9/50) and 15.4% (4/26), respectively. Routine urine culture and AST among pregnant women with preeclampsia should be introduced in the antenatal clinics to ensure prompt management. Delineation of maternal-fetal and neonatal outcomes among pregnant women with preeclampsia and UTIs would be of interest in future studies.

scholarly journals Mode of Delivery in Drug-Dependent Pregnant Women: A Case Control Study

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Ana Raquel Neves ◽  
Fabiane Neves ◽  
Isabel Santos Silva ◽  
Maria do Céu Almeida ◽  
Pitorra Monteiro
Keyword(s):  
Pregnant Women ◽  
Vaginal Delivery ◽  
Case Control Study ◽  
Mode Of Delivery ◽  
Case Control ◽  
Control Group ◽  
Maternal Characteristics ◽  
Drug Dependent ◽  
Route Of Delivery ◽  
Control Study

Objective. To determine the contribution of drug use during pregnancy to the route of delivery.Methods. A case-control study was conducted at a hospital in Coimbra, Portugal, between 2001 and 2014. Drug-dependent pregnant women (n=236) were compared with a control group of low risk women (n=228) in terms of maternal characteristics, obstetric history, pregnancy complications, and labor details. Factors that influenced the mode of delivery were determined. Statistical analysis was performed with SPSS v. 23.0 (IBM Corp.).pvalues < 0.05 were considered statistically significant.Results. Drug-dependent women presented a lower rate of cesarean delivery (18.2 versus 28.9%,p=0.006). After adjusting for the factors that were significantly related to the mode of delivery, drug dependency influenced the rate of cesarean section (β=0.567; 95% CI = 0.328–0.980). Within the drug-dependent group, the mode of delivery was significantly related to previous cesarean or vaginal delivery (p=0.008andp<0.001, resp.) and fetal presentation (p<0.001), but not with the type of drug, route of administration, or substitution maintenance therapy.Conclusions. The drug-dependent group presented a significantly higher rate of vaginal delivery. However, this was not associated with the behavioral factors analyzed. We hypothesize that other social and psychological factors might explain this difference.

scholarly journals Safety and Efficacy of Ferric Carboxymaltose in Anemic Pregnant Women: A Retrospective Case Control Study

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Anouk Pels ◽  
Wessel Ganzevoort
Keyword(s):  
Pregnant Women ◽  
Pregnancy Outcomes ◽  
Case Control Study ◽  
Case Control ◽  
Ferric Carboxymaltose ◽  
Control Group ◽  
Efficient Treatment ◽  
Safety And Efficacy ◽  
Anemia During Pregnancy ◽  
Control Study

Background. Anemia during pregnancy is commonly caused by iron deficiency and can have severe consequences for both the mother and the developing fetus. The aim of this retrospective study was to assess the safety and efficacy of intravenous ferric carboxymaltose (FCM) in pregnant women.Methods. All women treated with FCM for anemia during pregnancy between 2010 and 2012 at our institution were included. A matched control group was selected, including women who either were nonanemic or had anemia but were not considered for intravenous iron. Main outcome measures were maternal safety and pregnancy outcomes.Results. The study included 128 patients (FCM: 64; control: 64). Median FCM dose was 1000 mg and median gestational age at the time of first treatment was 34 weeks and 6 days. Median Hb increased from 8.4 g/dL (interquartile range 7.7; 8.9 g/dL) at the first FCM administration to 10.7 g/dL (9.8; 11.5 g/dL;n=46with available Hb at delivery) at the time of delivery, achieving levels similar to those in the control group (10.8 g/dL [9.8; 11.8 g/dL;n=48]). No treatment-related adverse events were reported and no statistically significant differences in pregnancy outcomes were observed between groups.Conclusions. Within the limitations of this case control study, FCM was a safe and efficient treatment of anemia during pregnancy.

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