Accuracy in clinical chemistry--does anybody care?

1994 ◽  
Vol 40 (6) ◽  
pp. 859-861 ◽  
Author(s):  
N W Tietz

Abstract The role of clinical chemistry in the diagnostic process has been enhanced by the evolution of better instrumentation and analytical techniques. The quality of some laboratory tests, however, has not kept pace with these advances. I present three examples--serum iron, serum lipase, and nonisotopic immunoassays--assays where some currently used methodologies are highly flawed. Causes for the less than optimal performance of some clinical laboratories are discussed.

Author(s):  
Graham Beastall ◽  
Desmond Kenny ◽  
Paivi Laitinen ◽  
Joop ten Kate

AbstractA definition has been agreed for the most senior professional (consultant) in clinical chemistry and laboratory medicine. A model job description for a consultant has been determined, which is intended to act as a toolkit to assist employing authorities and professional bodies to define the role of individual consultant posts. A total of 86 competences for a consultant have been designated and expressed in the form of simple generic proficiency standards. These competences have been allocated to six broad areas: clinical [13]; scientific [15]; technical [12]; communication [12]; management and leadership [20]; professional autonomy and accountability [14]. The competences are intended to be illustrative rather than definitive and to enable the duties of any consultant post to be defined. Assessment of competence is likely to entail consideration of qualifications, registration status, continuing professional development and performance review. The project is intended as a guide to European societies of clinical chemistry and laboratory medicine. The guide should be capable of local interpretation to encourage a greater degree of commonality in the role of the consultant whilst protecting national identity. The guide should stimulate international understanding and collaboration and contribute to an overall improvement in the quality of practice.


2019 ◽  
Vol 26 (6) ◽  
pp. 1721-1726
Author(s):  
Nikola Sabev ◽  
Denitsa Trancheva

“Clinical Laboratory” is an independent medical specialty, a dynamic clinical discipline of a scientific and applied nature. Laboratory researches, the results of which are objective indicators of the state of the organism, are of great importance in terms of modern medicine. Laboratory analyses help to achieve, within certain limits, such a result that can be used for the purpose of making the necessary medical decisions. “Laboratory Medicine” is a complex specialty, covering different directions: clinical chemistry, laboratory haematology, immunology, immunohematology, biology, drug monitoring and laboratory toxicology. A wide varietyof techniques is used for the analysis of biological fluids, the composition and properties of different types of cells, tissues, organs and systems.According to World Health Organization (WHO)data, in the past 20 years, the rate of morbidity within the population of nosologic units requiring high technologies and accuracy of diagnostic tests has increased. Modern revolution in clinical medicine complicates research methods and, as a result, increases significantly their value and cost.Laboratory units are widely considered to determine the status of each national healthcare system. Effectiveness of laboratory diagnostic process can be ensured by two key elements – high-tech equipment and professional staff. A need exists for identifying and using internal reserves with a view to the optimization of work volume and structures of laboratory and diagnostic units, being a promising and the most realisticdirection in the contemporary socio-economic situation.The mission of Clinical Laboratory departments is focused both on the provision of fast, adequate and accurate medical-diagnostic assistance, as well as on making effective use of any available material and technical resources and personnel potential. The problem being studied, its importance and the analysis of Clinical Laboratory activity are an essential component of the vision for this activity: high quality of clinical and laboratory results, timely and accurate diagnosis, adequate, timely and effective medical decisions.Main activities such as management; documentation of researches assigned and carried out; financial and economic aspects related to the valuation of laboratory analyses; tracking cost and available options for their optimization; reasonable time reduction for the production of laboratory analyses; introducing new high-performance technological equipment to improve the quality of laboratory activities and optimize the healing process have been researched and analysed in the Clinical Laboratory of “Kanev” University Multi-Profile Hospital for Active Treatment, Ruse.


1992 ◽  
Vol 14 (1) ◽  
pp. 9-15 ◽  
Author(s):  
K. Ozawa ◽  
P. Schnipeslky ◽  
H. L. Pardue ◽  
J. Place ◽  
A. Truchaud

This paper provides an in-depth description of the current applications of robotics in clinical laboratories. The trends and impact of the use of robotics in clinical chemistry in the forseeable future are also discussed.


1995 ◽  
Vol 41 (9) ◽  
pp. 1306-1312 ◽  
Author(s):  
R Schaffer ◽  
G N Bowers ◽  
R S Melville

Abstract The issuance of cholesterol as a Standard Reference Material (SRM) in 1967 started the National Institute of Standards and Technology (NIST; then named the National Bureau of Standards) on a major effort to help clinical laboratories establish and improve the quality of measurements they make. NIST now issues three kinds of SRMs for that purpose: analyte samples of certified purity as primary standards, serum samples having certified analyte concentrations as accuracy controls, and materials certified for calibrating instruments. In working with clinical laboratory scientists to establish Reference Methods (RMs) for measuring the analytes, NIST developed Definitive Methods (DMs) to use for evaluating RM accuracy and then used the DMs for assigning analyte values to its SRMs. The development of SRMs and DMs is discussed.


2019 ◽  
Vol 15 (2) ◽  
pp. 79-82
Author(s):  
Abhik Banerjee ◽  
Gopa Haldar Das ◽  
Rajarshi Sil

Mild cognitive impairment is an intermediate stage between the expected cognitive decline of normal ageing and the more serious decline of dementia. Dementia is typically diagnosed when acquired cognitive impairment has become severe enough to compromise social and/or occupational functioning. The elderly are at much greater risk for cognitive impairment. Unfortunately, most cases of cognitive impairment without apparent dementia go undetected and thereby untreated in primary care. Clinical diagnosis supported by appropriate use of diagnostic tests and biomarker is essential to improve the quality of life in these patients. In this article, we discussed the role of clinical laboratories in the diagnosis of cognitive impairment and dementia in the geriatric population.


AL MURABBI ◽  
2019 ◽  
Vol 4 (2) ◽  
pp. 177-200
Author(s):  
Ali Muhsin

The effort to improve Al-Qur'an reading and writing becomes the main factor is the improvement of the quality of human resources that is teacher. Teachers have characteristics as mentors who are able to show the dynamic interaction between teachers and learners. The purpose of the study to know how the role of teachers in an effort to improve the quality of literature Al-Qur`an in TPQ Miftahul Ulum Nglele Sumobito Jombang. This type of descriptive qualitative research with interview method, observation and documentation. Analytical techniques using data reduction (data reduction), data display (data presentation), data conclusing drawing / verification. In reading the Qur'an the learner is not a thing that goes without a process, but requires a concrete teacher's efforts. The result of the teacher's role in the effort to improve the literacy of the Qur'an is very satisfactory as evidenced by the santri can read Al-Qur an well and correctly.


Author(s):  
Atef Mejri ◽  
Badreddine Aloui ◽  
Khaoula Arfaoui

Due to the anatomical proximity of the last ileal loop and the bladder, Crohn’s disease can affect the urinary tract by the formation of an Enterovesical Fistula (EVF). Although rare, it represents a complication with a potential impact on the patient’s quality of life and it is often difficult to manage. In addition to the Computed Tomographic (CT) findings, several other examinations can contribute to the diagnosis of EVF, which calls for adequate management based on disconnection of the digestive tract from the bladder and maintenance of medical treatment. Despite therapeutic advances in the context of Crohn’s disease, the EVF remains a surgical indication. The present case reported is of a successfully managed EVF which was revealed by fecaluria aiming to emphasise the clinical aspects and various diagnostic tools with a special mention of the key role of medical imaging in the diagnostic process and the surgical management.


2020 ◽  
pp. 43-49
Author(s):  
Valery Karavaev ◽  
Marina Filosofova

the article observes the issues of improving the quality of medical care provided in medical organizations, the role of experts in this issue and other reserve opportunities for optimizing the Russian health care and improving the treatment and diagnostic process.


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