scholarly journals Comparison of Method Group Precision in Proficiency Testing of Clinical Chemistry Tests Before and After Two Major Changes: Reorganization of Proficiency Testing and Implementation of the Differential Benefit for the Quality of Laboratory Tests

2019 ◽  
Vol 39 (3) ◽  
pp. 336
Author(s):  
Haeil Park ◽  
Jongbo Cho
Keyword(s):  
Proficiency Testing ◽  
Laboratory Tests ◽  
Clinical Chemistry ◽  
Before And After ◽  
Clinical Chemistry Tests ◽  
Method Group

Accuracy in clinical chemistry--does anybody care?

1994 ◽  
Vol 40 (6) ◽  
pp. 859-861 ◽  
Author(s):  
N W Tietz
Keyword(s):  
Laboratory Tests ◽  
Serum Iron ◽  
Clinical Chemistry ◽  
Analytical Techniques ◽  
Optimal Performance ◽  
Diagnostic Process ◽  
Serum Lipase ◽  
Clinical Laboratories

Abstract The role of clinical chemistry in the diagnostic process has been enhanced by the evolution of better instrumentation and analytical techniques. The quality of some laboratory tests, however, has not kept pace with these advances. I present three examples--serum iron, serum lipase, and nonisotopic immunoassays--assays where some currently used methodologies are highly flawed. Causes for the less than optimal performance of some clinical laboratories are discussed.

scholarly journals Avaliação da adesão e qualidade de vida de portadores de HIV sob seguimento farmacoterapêutico / Evaluation of adhesion and quality of life of HIV carriers under pharmacoterapeutical follow up

2017 ◽  
Vol 7 (2) ◽  
pp. 3-9 ◽  
Author(s):  
Larissa Rocha Arruda de Souza ◽  
Ananda Pullini Matarazo ◽  
Matheus Pereira de Araújo ◽  
Oriana Sabatina D'Alessandro Romano ◽  
Ricardo Radighieri Rascado ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Viral Load ◽  
Pharmaceutical Care ◽  
Laboratory Tests ◽  
Educational Interventions ◽  
Form Analysis ◽  
Significant Difference ◽  
Before And After

Introdução: O seguimento farmacoterapêutico (STF) de pacientes com HIV tem grande importância, pois contribui para adesão ao tratamento. Objetivos: Avaliar adesão e qualidade de vida em pacientes em uso de terapia antirretroviral através de questionários padronizados, durante a assistência intensiva da equipe farmacêutica. Métodos: Foram acompanhados 15 pacientes HIV positivos que frequentam o Centro de Testagem e Aconselhamento. Cada paciente recebeu o seguimento por sete meses: 1º Encontro: aplicação dos questionários de adesão e qualidade de vida; aplicação do formulário de atenção farmacêutica; análise dos exames laboratoriais (carga viral e contagem de linfócitos T Cd4). 2º Encontro: apresentação do plano de metas e proposta de diário para o registro de tomada da medicação. 3º Encontro: acompanhamento do plano de metas; verificação de problemas relacionados aos medicamentos (PRM); intervenções educativas. 4º Encontro: acompanhamento do plano de metas; verificação de PRM; intervenções educativas sobre a medicação. 5º Encontro: aplicação dos questionários de adesão e qualidade de vida; análise dos exames laboratoriais. Resultados: A média de idade foi de 42,5 ± 8,8 anos. Em relação à contagem de linfócitos T-CD4 antes e após o STF, houve aumento estatisticamente significativo (p=0,0048) deste parâmetro. A carga viral de 13 dos 15 pacientes se tornou indetectável ou reduziu. Não houve diferença estatisticamente significativa na adesão e qualidade de vida quando comparados o antes e o depois do seguimento. Conclusão: A atenção farmacêutica mostrou-se importante para os pacientes com HIV, pois os mesmos apresentaram melhora significativa em seus parâmetros clínicos.Palavras-chave: Atenção farmacêutica; Seguimento farmacoterapêutico; HIVABSTRACTIntroduction: Pharmacotherapeutic follow-up study of HIV infected patients is of great importance as it contributes to treatment adherence. Aims: To evaluate adherence and quality of life in patients using antiretroviral therapy through standardized questionnaires, during the intensive care of the pharmaceutical team. Methods: Fifteen HIV positive patients attending the Testing and Counseling Center were followed. Each patient was followed-up for seven months: 1st Meeting: application of adherence questionnaires and quality of life; application of the pharmaceutical care form; analysis of laboratory tests (viral load and CD4 T lymphocyte counts). 2nd Meeting: presentation of the goals' plan and proposal of a diary for the registration of medication taking; 3rd Meeting: follow-up of the goals' plan; checking of problems related to medicines (PRM); educational interventions on medication. 4th Meeting: follow-up of the targets plan; PRM checking; educational interventions on medication. 5th Meeting: application of adhesion questionnaires and quality of life; analysis of laboratory tests. Results: The mean age was 42.5 ± 8.8 years. Regarding the T-CD4 lymphocyte count before and after pharmacotherapeutic follow-up, there was an increase in this statistically significant parameter (p=0.0048). The viral load of 13 of the 15 patients became undetectable or reduced. There was no statistically significant difference in adherence and quality of life when compared to before and after follow-up. Conclusion: Pharmaceutical Care has proved to be an important practice for HIV patients, for they have shown a significant improvement in their clinical parameters.Keywords: Pharmaceutical care; Pharmacotherapeutic follow-up; HIV

scholarly journals Accessing the relevance of tests for estimating the physiological quality of wheat grains

2020 ◽  
Vol 66 (No. 9) ◽  
pp. 477-482
Author(s):  
Larissa Correia ◽  
Lucas Pereira ◽  
Thaisa Matera ◽  
Renata Pereira ◽  
Andreia Suzukawa ◽  
...  
Keyword(s):  
Electrical Conductivity ◽  
Seedling Growth ◽  
Laboratory Tests ◽  
Wheat Grains ◽  
Chemical Treatments ◽  
Data Variability ◽  
Before And After ◽  
Methyl Thiophanate ◽  
Physiological Quality

The objective of this work was to investigate, before and after chemical treatment, the interrelationships of the physiological quality tests in wheat grains. Following the chemical treatments with (i) carboxin thiram; (ii) carboxin thiram + thiamethoxam; (iii) carboxin thiram + thiamethoxam + bio-stimulant; (iv) pyraclostrobin + methyl thiophanate + fipronil, and (v) pyraclostrobin + methyl thiophanate + fipronil + bio-stimulant, subsequently the grains were assessed for their physiological potential. The physiological potential of the grains could be differentiated based on the electrical conductivity, seedling growth, and emergence in sand tests. In conclusion, the use of the active ingredients changed the correlation between laboratory tests with crop emergence in the sand as well as altered the relevance of the tests for sorting the treated grains into different physiological potential. But, the seedling growth tests and the electrical conductivity were, together, the parameters most relevant for explaining the data variability.  

Diagnostic performances of clinical laboratory tests using Triton X-100 to reduce the biohazard associated with routine testing of Ebola virus-infected patients

2015 ◽  
Vol 53 (12) ◽  
Author(s):  
Massimo Tempestilli ◽  
Luigia Pucci ◽  
Stefania Notari ◽  
Antonino Di Caro ◽  
Concetta Castilletti ◽  
...  
Keyword(s):  
Laboratory Tests ◽  
Ebola Virus ◽  
Clinical Laboratory ◽  
Clinical Symptoms ◽  
Virus Disease ◽  
Clinical Chemistry ◽  
Chemical Agent ◽  
Enveloped Virus ◽  
Before And After ◽  
Triton X

AbstractEbola virus, an enveloped virus, is the cause of the largest and most complex Ebola virus disease (EVD) outbreak in West Africa. Blood or body fluids of an infected person may represent a biohazard to laboratory workers. Laboratory tests of virus containing specimens should be conducted in referral centres at biosafety level 4, but based on the severity of clinical symptoms, basic laboratories might be required to execute urgent tests for patients suspected of EVD. The aim of this work was to compare the analytical performances of laboratory tests when Triton X-100, a chemical agent able to inactivate other enveloped viruses, was added to specimens.Results of clinical chemistry, coagulation and haematology parameters on samples before and after the addition of 0.1% (final concentration) of Triton X-100 and 1 h of incubation at room temperature were compared.Overall, results showed very good agreement by all statistical analyses. Triton X-100 at 0.1% did not significantly affect the results for the majority of the analytes tested.Triton X-100 at 0.1% can be used to reduce the biohazard in performing laboratory tests on samples from patients with EVD without affecting clinical decisions.

scholarly journals Assessment of Coverage and Quality of Selected Clinical Chemistry Tests among Medical Laboratories of Health Facilities in Jimma Zone, South West Ethiopia

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Aklilu Getachew ◽  
Waqtola Cheneke ◽  
Yaregal Asres ◽  
Shiferaw Bekele ◽  
Estifanos Kebede
Keyword(s):  
Reference Range ◽  
Clinical Chemistry ◽  
Health Facilities ◽  
Medical Laboratories ◽  
South West ◽  
Jimma Zone ◽  
Allowable Error ◽  
Clinical Chemistry Tests ◽  
South West Ethiopia

Background. Medical laboratories play essential roles in measurement of analyte in clinical sample for the diagnosis and monitoring of diseases. Thus, data generated from the laboratory have to be reliable for which strict quality assurance is maintained. Objective. To assess the coverage and quality of selected clinical chemistry tests among medical laboratories of health facilities in, Jimma Zone, South West Ethiopia. Methods. A cross-sectional study was conducted at Jimma Zone on health facilities from August 15 to September 15, 2014. Eighty-six health facility laboratories were included in the study. We classified laboratories into laboratories with clinical chemistry service and those without clinical chemistry service clusters and those with clinical chemistry laboratory were again clustered according to their level. Data were collected by direct observation, interview, and proficiency testing (PT). The collected data were analyzed and compared with CLIA PT goal for TEa by considering total allowable error ± 20%, ±10%, ±15%, and ±20 for each analyte, ALT, glucose, creatinine, and total bilirubin, respectively. Result. From total of 86 health facilities with laboratories, 23.3% (n=20) had clinical chemistry service, of which 77.2% results were reported outside of the allowable error limit. Conclusion. According to this study the availability of clinical chemistry test service was very minimal and facilities giving the service do not fulfill the minimum standard for quality; thus clients were either getting wrong clinical decision or misdiagnosed. Therefore, the external and internal quality assessment programs should be reviewed very well. Those laboratories whose report was outside of the allowable error should have to report results with the appropriate reference range so that physicians consider that. Establishment of local clinical chemistry reference range can also minimize the problem.

Plasma enzyme activities in primary hypothyroidism.

1984 ◽  
Vol 30 (2) ◽  
pp. 323-325 ◽  
Author(s):  
G H White ◽  
R N Walmsley
Keyword(s):  
Enzyme Activities ◽  
Medical Staff ◽  
Laboratory Tests ◽  
Clinical Chemistry ◽  
Primary Hypothyroidism ◽  
Diagnostic Problem ◽  
Plasma Enzyme ◽  
Professional Assistance ◽  
Clinical Chemistry Tests

Abstract Results of clinical chemistry tests are often initially interpreted by relatively inexperienced junior medical staff, and therefore a major role of clinical chemists is to ensure that their laboratory tests are utilized and interpreted appropriately. The cases described below demonstrate the interaction of a diagnostic problem and clinical inexperience in an area where clinical chemists can, and should be, of professional assistance.

Kepuasan Masyarakat Terhadap Pelayanan Kelurahan Setelah Pemekaran Di Tangerang Selatan

Liquidity ◽  
2018 ◽  
Vol 2 (2) ◽  
pp. 151-159
Author(s):  
Pitri Yandri
Keyword(s):  
Public Perception ◽  
Service Personnel ◽  
Urban Services ◽  
Hospitality Workers ◽  
Care Workers ◽  
Before And After ◽  
Cartesian Diagram ◽  
Better Than

The purpose of this study is (1) to analyze public perception on urban services before and after the expansion of the region, (2) analyze the level of people's satisfaction with urban services, and (3) analyze the determinants of the variables that determine what level of people's satisfaction urban services. This study concluded that first, after the expansion, the quality of urban services in South Tangerang City is better than before. Secondly, however, public satisfaction with the services only reached 48.53% (poor scale). Third, by using a Cartesian Diagram, the second priority that must be addressed are: (1) clarity of service personnel, (2) the discipline of service personnel, (3) responsibility for care workers; (4) the speed of service, (5) the ability of officers services, (6) obtain justice services, and (7) the courtesy and hospitality workers.

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