Retrogated compressed sensing cine in one minute
Abstract Funding Acknowledgements Type of funding sources: None. PURPOSE Real-time compressed sensing cine (CSrt) provides reliable quantifications for both ventricles but impairs image quality . This aim of this study was to assess the accuracy of left (LV) and right ventricular (RV) volumes, ejection fraction and mass quantifications based on a retrogated segmented compressed sensing-fashioned accelerated 2D cine sequence (CSrg). Image quality was also evaluated. METHOD AND MATERIALS Thirty patients were enrolled. Each patient underwent the reference retrogated segmented steady-state free precession cine sequence (SSFPref), the first generation real-time CSrt cine and the segmented retrogated prototype CSrg sequence providing the same numbers and positions of slices. Functional parameters quantification was performed on SSFPref and CSrg images sets. Image quality was assessed for the three sequences by using edge sharpness which is an estimate of the edge spread function. RESULTS Mean scan times were SSFPref = 512 ± 15 s, CSrt = 24 ± 5 s and CSrg = 58 ± 15 s. CSrg provided LV and RV functional parameters (end-systolic, end-diastolic, ejection fraction and LV mass) which were not significantly different from the one assessed with SSFPref (p > 0.05). Edge sharpness was significantly better with CSrg (0.083 ± 0.013 pixel-1) than with CSrt (0.070 ± 0.011 pixel-1; p = 0.0004) and not different from the reference techniques (0.075 ± 0.016 pixel-1; p = 0.0516). Inter and intrarater variabilities demonstrated intraclass correlation coefficients over 0.96. CONCLUSION CSrg cine provides in one minute an accurate quantification of LV and RV functional parameters without compromising the sharpness of myocardial boarders which was impaired by the first-generation real-time compressed sensing sequence. Abstract Figure. Image quality and volumes assessment