scholarly journals Cardiac CT in asymptomatic diabetes mellitus: role of non-invasive atherosclerosis imaging in high-risk asymptomatic individuals

2015 ◽  
Vol 16 (10) ◽  
pp. 1060-1061
Author(s):  
Filippo Cademartiri ◽  
Erica Maffei ◽  
Stefano Nistri ◽  
Jonathon Leipsic
2018 ◽  
Vol 6 (1) ◽  
pp. e000489 ◽  
Author(s):  
Nabil Sulaiman ◽  
Ibrahim Mahmoud ◽  
Amal Hussein ◽  
Salah Elbadawi ◽  
Salah Abusnana ◽  
...  

ObjectiveThe objective of this study was to develop a simple non-invasive risk score, specific to the United Arab Emirates (UAE) citizens, to identify individuals at increased risk of having undiagnosed type 2 diabetes mellitus.Research design and methodsA retrospective analysis of the UAE National Diabetes and Lifestyle data was conducted. The data included demographic and anthropometric measurements, and fasting blood glucose. Univariate analyses were used to identify the risk factors for diabetes. The risk score was developed for UAE citizens using a stepwise forward regression model.ResultsA total of 872 UAE citizens were studied. The overall prevalence of diabetes in the UAE adult citizens in the Northern Emirates was 25.1%. The significant risk factors identified for diabetes were age (≥35 years), a family history of diabetes mellitus, hypertension, body mass index ≥30.0 and waist-to-hip ratio ≥0.90 for males and ≥0.85 for females. The performance of the model was moderate in terms of sensitivity (75.4%, 95% CI 68.3 to 81.7) and specificity (70%, 95% CI 65.8 to 73.9). The area under the receiver-operator characteristic curve was 0.82 (95% CI 0.78 to 0.86).ConclusionsA simple, non-invasive risk score model was developed to help to identify those at high risk of having diabetes among UAE citizens. This score could contribute to the efficient and less expensive earlier detection of diabetes in this high-risk population.


Author(s):  
Anvesha Kumar ◽  
Purshottam Bantaklal Jaju

Background: Continuous fetal heart monitoring in all pregnant women in labour has gained prominence in obstetric practice in the recent years. The aim of this study was to emphasize on the role of admission cardiotocography (CTG) in labour as a predictor of foetal outcome in high risk pregnancies.Methods: This was a prospective observational study done on 340 high risk patients admitted in labour with a period of gestation of ≥37 weeks. An admission CTG which consists of a 20-minute recording of FHR and uterine contractions was taken and the foetal outcome was correlated with it. The non-parametric Chi-square test was used for statistical calculations and a p valve of <0.05 was considered to designate statistical significance.Results: The admission CTG was reactive in 69.4% of all patients, equivocal in 22.2% and pathological in 8.4% of the 340 recruited patients. A total of 37.5% of the patients were post-dated followed by 20.6% of pregnancy incuded hypertensive patients. The neonatal outcomes in terms of fetal distress, meconium stained liquor, NICU admission were considerably higher in pathological test. The specificity of the test was 53.3%, and the negative predictive was    86.49%.Conclusions: Admission CTG is a simple, useful screening test and serves as a non-invasive tool in forecasting the adverse foetal outcomes in high risk pregnancies.


Hypertension ◽  
2015 ◽  
Vol 66 (suppl_1) ◽  
Author(s):  
Jay Cohn ◽  
Sue Duval ◽  
Natalia Florea ◽  
Lynn Hoke ◽  
Daniel Duprez

Hypertension is a cardiovascular (CV) disease with high risk for CV morbid events (ME) that benefits from anti-hypertensive therapy. Resting blood pressure (BP) >140/90 mmHg serves as the diagnostic criterion for hypertension, and management has been aimed at BP reduction. Progression of CV disease in the absence of elevated blood pressure identifies individuals who might benefit from CV-protective therapy but are not currently being recognized as in need of treatment. In 2017 asymptomatic individuals evaluated for early functional and structural CV abnormalities, 1534 not taking anti-hypertensive drugs were available to determine the relationship between office blood pressure and the severity of CV abnormalities, as defined by a 10-test non-invasive disease score (DS) of 0-20. Previous studies have documented the high predictive value of DS for future CVME. The population was 53% male, average age 50±11 years, BP 122/77mmHg, LDL cholesterol 129±38 mg/dL, HDL 52±17mg/dL, triglycerides 109 mg/dL. DS was adjusted by eliminating the score for BP, but 9-test DS was still directly related to BP: 2.3 in those (n=550) <120/80 mmHg (Group I), 3.2 in those 120-129/80-85 mmHg (n=600) (Group II), 4.1 in those 130-139/85-89 mmHg (n=236) (Group III), and 5.7 in those 140+/90+mmHg (n=148) (Group IV). Nonetheless, DS of >6 indicative of high risk was present in 10% of Group I, 20% of Group II and 30% of Group III. BP was largely overlapping in individuals with no CV disease (DS 0-2), early disease (DS 3-5) and advanced disease (DS 6+). Therefore, reliance on resting BP leaves many at-risk individuals undiagnosed and untreated for early CV disease likely to progress. The hypertensive state exists in the absence of elevated BP and should be recognized and treated to prevent CVME.


2009 ◽  
Vol 203 (2) ◽  
pp. 442-448 ◽  
Author(s):  
Juan J. Rivera ◽  
Khurram Nasir ◽  
Eue-Keun Choi ◽  
Yeonyee E. Yoon ◽  
Eun-Ju Chun ◽  
...  

Author(s):  
Jayanthi Hari Kishan ◽  
Vollala Shravan Kumar

Introduction: Coronavirus Disease 2019 (COVID 19) pneumonia is a rapidly spreading disease and which causes morbidity and mortality of many patients. Diabetes mellitus is co-morbidity which is considered as the risk factor for COVID 19. Well-controlled diabetes is associated with better outcomes than poorly controlled diabetes. Measurement of glycated haemoglobin (HbA1c) is the standard method for assessing long term glycaemic control. Regardless of the level of hyperglycaemia, improvement in glycaemic control will lower the risk of diabetic complications. Aim: This study was conducted to identify the role of glycaemic control (HbA1c) in predicting the severity of illness in patients with COVID 19 pneumonia. Materials and Methods: This was a retrospective observational study of (51 diabetic and 51 were non diabetic) patients at Kamineni Academy of Medical Sciences, Hyderabad, India. The patients diagnosed with COVID 19 pneumonia, which includes both diabetics and non diabetics from June 2020 to September 2020. Patients age, sex, baseline HbA1c levels, and oxygen requirement during the hospital stay were analysed using Statistical Package for the Social Sciences (SPSS) software version 22.0. The Chi-Square test was used to analyse qualitative data and p-value significant at level <0.05. Results: In the study among diabetics (n=51), 20 (39.2%) were on room air, 24 (47.1%) required intermittent oxygen support, 3 (5.9%) high flow oxygen, and 4 (7.8%) non invasive ventilator support. Among non diabetics (n=51), 28 (54.9%) were on room air, 18 (35.3%) on intermittent oxygen, 2 (3.9%) high flow oxygen, and 3 (5.9%) Non Invasive Ventilator (NIV) support. It was observed that patients with HbA1c measurements with poor glycaemic control required more oxygen support during treatment in diabetics (p-value:0.469) Conclusion: In the present study, patients with poor glycaemic control required insignificantly, more oxygen support than patients with good glycaemic control.


2012 ◽  
Vol 11 (4) ◽  
pp. 90
Author(s):  
G. Gluck ◽  
M.M. Chirita ◽  
R. Stoica ◽  
D. Daia ◽  
I. Sinescu

2021 ◽  
Vol 9 (10) ◽  
pp. 2415-2422
Author(s):  
Rashmi Kathait ◽  
Ajai Kumar Pandey

Objective: The present review was carried out with the objectives of identifying the role of Yogāsana (yogic practices) and Prānāyam (breathing practices) as a modality to prevent and treat diabetes. Data Source: The fea- sible beneficial effects of Yogāsana (yogic practices) and Prānāyam (breathing practices) on diabetes were as- sessed, which is based on relevant classical texts along with textbooks of contemporary medical sciences. Be- sides, recent research articles related to clinical studies conducted in various institutions as available on the inter- net and published in authentic databases (Pub-Med, Google Scholar, Web of Science etc.) were also referred through the ancestry approach. Review Methods: The possible correlation has been made between collected in- formation and has been presented systematically. The quality of the studies was assessed by the author and logi- cally presented in this context. Result and Discussion: Yoga offers a non-invasive way to manage various clini- cal conditions up to some extent. It can be prescribed with other systems of medicines as an adjuvant for health promotion. Recent evidence suggests that Yoga and controlled lifestyle measures reduce blood sugar load in peo- ple with diabetes. Keywords: Yoga, Yogāsana, Prānāyam, Diabetes mellitus, Insulin resistance, lifestyle disease.


2019 ◽  
Vol 13 (5) ◽  
pp. 261-266 ◽  
Author(s):  
Fay Y. Lin ◽  
Todd C. Villines ◽  
Jagat Narula ◽  
Leslee J. Shaw

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