scholarly journals Echocardiographic characteristics of cardiac myxoma

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
P Koritnik ◽  
N Pavsic ◽  
M Bervar ◽  
K Prokselj
Keyword(s):  
Left Atrium ◽  
Tumor Size ◽  
Cardiac Tumor ◽  
Imaging Modality ◽  
Cardiac Computed Tomography ◽  
Cardiac Myxoma ◽  
Clinical Manifestations ◽  
Cardiac Tumors ◽  
Number Of Patients ◽  
Cardiac Masses

Abstract Background Accurate imaging differentiation of various cardiac masses is pivotal due to differences in clinical management and treatment. The most common primary cardiac tumor is cardiac myxoma (CM), which is typically located in the left atrium attached to the interatrial septum. Although benign, serious clinical manifestations may occur and surgical treatment of CM is warranted in most cases. Echocardiography is the most common imaging modality, with a reported sensitivity of 90–96%, however accurate diagnosis can be challenging due to the heterogeneous morphological presentation of CM. Purpose The aim of this study was to determine the utility of echocardiography in CM diagnosis. Methods We retrospectively analyzed the echocardiographic and pathohistological findings of all consecutive patients admitted to our cardiology department for possible CM between 2005 and 2020. Results During the 15-year period, 73 patients were admitted for diagnostic evaluation of a possible CM. Subsequently, 54 patients (74%) were diagnosed with CM or another non-myxomal (NM) cardiac tumor, while in others cardiac masses of other etiologies (thrombus, infective endocarditis, etc.) were diagnosed (Figure 1). All but one patient with CM or NM cardiac tumor were treated surgically at our institution and pathohistological specimens were obtained from the resected tumor. There was a significant female preponderance (n=34, 63%) and the mean age at the time of surgery was 64±14 years. Based on the preoperative echocardiographic findings, 45 (85%) tumors were diagnosed as CM and 8 as NM cardiac tumors (Figure 1). Evaluation of pathohistological specimens revealed CM in 39 of 53 (74%) operated patients. Patohistiologically, a NM cardiac tumor was diagnosed in 7 patients who were preoperatively classified as CM. The sensitivity and specificity of preoperative echocardiography for the detection of CM were 97% and 50%, respectively (Figure 1). The echocardiographic characteristics of pathohistologically confirmed CM were compared to cases of NM cardiac tumors. The comparison between the two groups revealed statistically significant differences in localization and tumor size. All NM cardiac tumors were located in an atypical position and 72% of CM were found in a typical position within the left atrium (p<0.001). NM cardiac tumors were also significantly smaller than CM (25.1±12.6 mm vs. 37.5±18.5 mm, p=0.029). Conclusion Our single-center study confirms the excellent sensitivity of echocardiography for CM diagnosis. The specificity of echocardiography was modest, thus caution is warranted due to a wide differential diagnosis of CM. The diagnosis of CM seems to be less likely with atypical tumor location and small tumor size. Other non-invasive imaging modalities such as cardiac computed tomography or magnetic resonance imaging should be considered in such cases. FUNDunding Acknowledgement Type of funding sources: None. Figure 1. Flow chart showing the number of patients diagnosed with CM on preoperative echocardiography.

scholarly journals Thymic pathology and cardiac myxomas: Coincidence or a closer relationship?

2018 ◽  
Vol 88 (1) ◽  
Author(s):  
Sotirios D. Moraitis ◽  
Apostolos C. Agrafiotis ◽  
Dimitrios Pappas ◽  
Chrysovalantis Pothitakis ◽  
Maria Stergianni ◽  
...  
Keyword(s):  
Left Atrium ◽  
Cardiac Myxoma ◽  
Anterior Mediastinum ◽  
Thymus Gland ◽  
Thymic Hyperplasia ◽  
Cardiac Tumors ◽  
Cardiac Myxomas ◽  
Thymic Tumors

Myxomas are the most common benign cardiac tumors and are located more frequently in the left atrium. In the literature there are cases describing the coexistence of thymic tumors and cardiac myxomas. In the case reported herein, during the resection of a cardiac myxoma, an enlarged thymus gland was encountered and resected. The histological exam revealed a thymic hyperplasia. The aim of this case study is to assess the need of conducting further studies in order to identify a common histological pathway between thymic lesions and cardiac myxomas. The diagnosis of a cardiac myxoma could justify a further workup of the anterior mediastinum in order not to overlook a lesion of thymic origin.

Giant Right Atrial Myxoma: The Importance of Transesophageal Echocardiography during Diagnosis, Evaluation, and Resection

2016 ◽  
Vol 4 (2) ◽  
pp. 74-78
Author(s):  
Elizabeth Ungerman ◽  
Wendy Haft
Keyword(s):  
Transesophageal Echocardiography ◽  
Left Atrium ◽  
Transthoracic Echocardiography ◽  
Atrial Myxoma ◽  
Right Atrial ◽  
Cardiac Tumors ◽  
Transient Ischemic Attacks ◽  
Outflow Obstruction ◽  
Right Atrial Myxoma ◽  
Cardiac Masses

ABSTRACT Most cardiac tumors are benign myxomas, and are most commonly found in the left atrium. Such tumors are identified either during symptomatic workup or found incidentally. We present a case in which a patient with recurrent transient ischemic attacks and syncope was found to have a giant right atrial myxoma with subsequent right atrial outflow obstruction. The mass was initially diagnosed on transthoracic echocardiography and its full scope was detailed utilizing transesophageal echocardiography (TEE). With swift intervention, the mass was successfully removed with the help of TEE guidance and the patient made a full recovery. The importance of TEE both preoperatively and intraoperatively during resection of giant cardiac masses is highlighted. How to cite this article Ungerman E, Haft W. Giant Right Atrial Myxoma: The Importance of Transesophageal Echocardiography during Diagnosis, Evaluation, and Resection. J Perioper Echocardiogr 2016;4(2):74-78.

scholarly journals Left Atrial Myxoma with Tricuspid Regurgitation: Pathophysiology, Diagnostic Approach, and Management

2015 ◽  
pp. 28-3
Author(s):  
Prima Almazini ◽  
Bambang Budi Siswanto ◽  
Nani Hersunarti ◽  
Rarsari Soerarso ◽  
Amiliana M Soesanto
Keyword(s):  
Cardiac Myxoma ◽  
Clinical Manifestations ◽  
Definitive Treatment ◽  
Surgical Removal ◽  
Cardiac Tumors ◽  
Gold Standard Method ◽  
Left Atrial Myxoma ◽  
Associated Conditions ◽  
Cardiac Myxomas ◽  
Primary Cardiac Tumors

Cardiac myxomas are the most common primary cardiac tumors. Myxoma are more common in women. Clinical manifestations can mimic many cardiac and noncardiac conditions. Transthoracic echocardiography (TTE) is the gold standard method in the diagnosis of cardiac myxoma. The management of cardiac myxoma are medical therapy for the treatment of associated conditions and surgical removal as the definitive treatment.

scholarly journals Intracardiac Masses I-Mass Study Single Center Experience Within 12 Years

2021 ◽  
Author(s):  
Zehra Bugra ◽  
Samim Emet ◽  
Berrin Umman ◽  
Pelin Karaca Ozer ◽  
Murat Sezer ◽  
...  
Keyword(s):  
Autoimmune Diseases ◽  
Malignant Tumors ◽  
Thrombus Formation ◽  
Imaging Modality ◽  
Benign Tumors ◽  
Cardiac Tumors ◽  
Cross Sectional ◽  
Lung Cancers ◽  
Intracardiac Masses ◽  
Cardiac Masses

Abstract Objective : The aim of this cross-sectional, retrospective, descriptive study was to review and classify cardiac masses systematically and to determine their frequencies.Methods : The medical records of 64,862 consecutive patients were investigated within 12 years. Every patient with a cardiac mass imaged by transthoracic echocardiography (TTE) and confirmed with an advanced imaging modality such as transesophageal echocardiography (TEE), computed tomography (CT) and / or cardiac magnetic resonance imaging (CMR) was included. Acute coronary syndromes triggering thrombus formation, vegetations, intracardiac device and catheter related thrombi were excluded.Results : Data demonstrated 127 (0.195 %) intracardiac masses consisting of 33 (0.050 %) primary benign, 3 (0.004 %) primary malignant, 20 (0.030 %) secondary tumors, 3 (0.004 %) hydatid cysts and 68 (0.104 %) thrombi respectively. The majority of primary cardiac tumors were benign (91.67 %), predominantly myxomas (78.79 %), and the less malignant (8.33 %). Secondary cardiac tumors were common than the primary malignant tumors (20:3), with male dominancy (55 %), lymphoma and lung cancers were the most frequent. Intracardiac thrombi was the majority of the cardiac masses, thrombi accompanying malignancies were in the first range (n=17, 25%), followed by autoimmune diseases (n=13, 19.12 %) and ischemic heart disease with low ejection fraction (n=12, 17.65 %).Conclusion: This retrospective analysis identified 127 patients with cardiac masses. The majority of benign tumors were myxoma, the most common tumors that metastasized to the heart were lymphoma and lung cancers, and the thrombi associated with malignancies and autoimmune diseases were the most frequent.

Giant Left Atrial Myxoma Misdiagnosed As Schizophrenia: A Case Report

2020 ◽  
Author(s):  
Hongfei Xu ◽  
Wei Si ◽  
Yiran Zhang ◽  
Yiming Ni ◽  
Weidong Li
Keyword(s):  
Left Atrium ◽  
Left Atrial ◽  
Tumor Resection ◽  
Cardiac Myxoma ◽  
Health Department ◽  
Cardiac Tumors ◽  
Left Atrial Myxoma ◽  
Giant Tumor ◽  
Atrial Enlargement ◽  
Mental Health Department

Abstract Background: Primary cardiac tumors are rare. Myxoma is the most common cardiac tumor and presents in the left atrium. Improvements tend to occur with early diagnosis, and with the help of high-resolution imaging technology, such as transesophageal echocardiography (TEE). Patients typically present with tightness of the chest, fatigue and lassitude. There are also cases of misdiagnosis and missed diagnosis. Case presentation: A 59-year-old Chinese woman complained of tightness in her chest, fatigue and lassitude for eight years. She had been misdiagnosed with schizophrenia by the local rural hospital. Computed tomography (CT) confirmed a giant mass in the left atrium, and transthoracic echocardiography (TTE) revealed left atrial enlargement with an occupying lesion. For this patient, we performed tumor resection surgery with a cardiopulmonary bypass. The giant tumor was partially detached during the operation, and the thrombus was removed successfully. After the operation, the mental health department of our hospital thought that the patient's diagnosis of schizophrenia was misdiagnosed. The patient recovered well and appeared rejuvenated after the operation. A two-year follow-up found no adverse events since the operation. Conclusions: When making a diagnosis for a patient who presented with tightness of the chest, we need to administer a cardiac physical examination and echocardiography. The physician diagnosing schizophrenia needs to first rule out any organic diseases. A careful and complete resection of the cardiac myxoma is a vital operation, due to the risk of thromboembolism.

Left Atrial Myxoma and Antiphospholipid Syndrome—A Case Report

2021 ◽  
Author(s):  
Mijo Meter ◽  
Diana Meter ◽  
Toni Ceprnja ◽  
Dijana Perkovic
Keyword(s):  
Case Report ◽  
Antiphospholipid Syndrome ◽  
Lupus Erythematosus ◽  
Left Atrial ◽  
Imaging Modality ◽  
Cardiac Myxoma ◽  
Atrial Myxoma ◽  
Cardiac Tumors ◽  
Left Atrial Myxoma ◽  
Initial Imaging

AbstractCardiac myxoma (CM) is the most frequent type of primary cardiac neoplasm and is responsible for 58 to 80% of primary cardiac tumors. The antiphospholipid syndrome (APS) occurs most commonly in the systemic lupus erythematosus but it can be also found in other conditions. The coexistence of CM and APS is rarely described in the literature. We report an unusual case of the left atrial myxoma and concomitant APS in a female patient who presented with right-sided hemiplegia. Although rare, we must think about the CM in patients with a newly diagnosed APS and left atrial mass. Nevertheless, we must make a distinction from other possible cardiac structures, especially atrial thrombus. Transthoracic echocardiography is the most frequently used initial imaging modality to detect CM. The aim of this case report was to emphasize that additional imaging modalities and multidisciplinary approach are mandatory in making a proper diagnosis and to choose a further treatment strategy.

scholarly journals Mediastinal Tuberculoma Mimicking Malignant Cardiac Tumor: A Case Report

2020 ◽  
Author(s):  
Fengjuan Yao
Keyword(s):  
Pulmonary Artery ◽  
Transthoracic Echocardiography ◽  
Cardiac Tumor ◽  
Multimodality Imaging ◽  
Clinical Manifestations ◽  
Left Pulmonary Artery ◽  
Tissue Mass ◽  
Antituberculosis Treatment ◽  
Contrast Enhanced ◽  
Cardiac Masses

Background: The clinical manifestations of cardiac masses are diverse and lack specificity. Here we report a cardiacmass detected by transthoracic echocardiography. Multimodality imaging and pathological findings after the operationconfirmed the mass as mediastinal tuberculoma.Case presentation: A 45-year-old male patient was admitted to our hospital reporting chest tightness, weight loss, and dyspnea for 3 months after exercise. Transthoracic echocardiography showed that there were a large number of pericardial effusions and the soft tissue mass measuring 7.7 cm × 4.5 cm in the upper mediastinum, which oppressed the right pulmonary artery and accelerated the blood flow of the left pulmonary artery. Contrast-enhanced ultrasonography showed degenerative inhomogeneous high enhancement of and an unclear boundary in the mass. Contrast-enhanced chest CT revealed punctate and patchy calcification in and uneven enhancement of the mass and the lymph nodes around the aortic arch. The mass was diagnosed as a malignant mediastinal tumor. Pathological analysis of the mass revealed chronic granulomatous tuberculosis. The symptoms abated significantly after antituberculosis treatment. The patientremained asymptomatic during follow-up.Conclusion: This report presents a rare case of mediastinal tuberculoma mimicking a malignant cardiac tumor. Multimodalityimaging should be incorporated for differentiation of cardiac masses.

scholarly journals Sudden death syndrome caused by cardiac tumor

2020 ◽  
Vol 54 (1) ◽  
pp. 44-49 ◽  
Author(s):  
Dušica Petrović-Rodić ◽  
Marko Spasić ◽  
Biljana Popovska-Jovičić ◽  
Danijela Milošev ◽  
Slobodanka Mitrović
Keyword(s):  
Cardiac Tumor ◽  
Clinical Case ◽  
Staining Method ◽  
Cardiac Myxoma ◽  
Sudden Death Syndrome ◽  
Biological Behavior ◽  
Cardiac Tumors ◽  
Vital Organ ◽  
Potentially Malignant ◽  
The One

Cardiac tumors are not a common pathology. However, due to their occurrence in the vital organ, they bare an extremely important clinical significance. According to biological behavior, they are divided into 2 groups, primary (benign and malignant), which are less frequent and secondary (metastatic), which are more common. Among all primary benign cardiac tumors, myxoma is the one that occurs most often. A great number of studies indicate that it originates from multipotent mesenchymal cells of the septum of the left atrium. It is due to its localization that some authors consider it potentially malignant. This paper presents a case of cardiac myxoma which is echocardiographically diagnosed in a 34-year-old woman who died suddenly, several days before the scheduled surgery. The diagnosis of the disease was confirmed after the autopsy, by a routine haematoxylin-eosin (H&E) staining method and an additional immunohistochemistry method (IHC). By presenting a rare clinical case, we emphasize the fact that every diagnosed cardiac tumor requires immediate cardiac surgery without delay.

scholarly journals The Question of Relapse of a Cardiac Myxoma: an Unusual Case from Practice

2021 ◽  
pp. 35-41
Author(s):  
R. M. Vitovskiy ◽  
V. V. Isaіenko ◽  
O. A. Pishchurin ◽  
I. G. Jakovenko ◽  
V. F. Onishchenko
Keyword(s):  
Left Atrium ◽  
Unusual Case ◽  
Thoracoscopic Surgery ◽  
Cardiac Myxoma ◽  
Carney Complex ◽  
Left Ventricular ◽  
Surgical Removal ◽  
Cardiac Tumors ◽  
Careful Study ◽  
Heart Tumors

Various studies demonstrate that recurrence of cardiac myxoma (CM) occurs in 2.1–5.3% of cases. In cases of treatment of familial myxoma, the need for reoperations can reach 20–25%. It should be taken into account that among all benign cardiac tumors, CM is detected in up to 80% of cases, and the need for its surgical removal is beyond doubt. The aim. To present a case that is of particular interest due to an unusual multiple myxomas lesion of the heart of multi-chamber localization. Material and methods. This article presents an unusual case of detecting multiple myxomas of multi-cameral heart lesions 6 years after removal of myxoma of the left atrium of typical localization. The distinguishing feature of the course of the disease lies in the fact that in this case, a careful study of the life history did not reveal the characteristic signs of familial myxomas and Carney complex which is most often characteristic of multi-chamber lesions of the heart by a tumor process. At the same time, during the surgical removal of the myxoma of the left ventricle, the myxomas of the left and right atrium were revealed, which began to grow. A technical feature of the removal of the left ventricular myxoma of the apical localization was the use of video cameras and instruments for thoracoscopic surgery, which greatly facilitated revi-sion and removal of the hard-to-reach neoplasm. Our experience in surgical treatment of CM equals to 868 operations. Wherein, repeated operations performed in 12 patients were due to recurrence or appearance of a tumor in place other than the primary localization. Conclusions. CM recurrence is one of infrequent complications in the postoperative period, which, however, requires some vigilance and annual Echo monitoring. In the vast majority of cases, CM was represented by the so-called sporadic myxomas, which are more often localized in the left atrium, and rarely recur. If CM is suspected, it is necessary to exclude the possibility of “myxoma syndrome”, which has the frequency of 0.8%, according to our data. The use of the instruments for thoracoscopic surgery can greatly facilitate the removal of hard-to-reach heart tumors localization.

scholarly journals Rare Cardiac Myxoma with A Hard Texture: A Case Report

2020 ◽  
Author(s):  
Hongfei Xu ◽  
Yanjia Gu ◽  
Liang Ma ◽  
Yiming Ni ◽  
Weidong Li
Keyword(s):  
Elective Surgery ◽  
Cardiac Myxoma ◽  
Clinical Manifestations ◽  
Surgical Excision ◽  
Cardiac Tumors ◽  
Rare Type ◽  
Primary Tumors ◽  
Case Presentation ◽  
Preoperative Examination

Abstract Background: Primary tumors of the heart are uncommon but not rare. Myxoma comprises 50% of all benign cardiac tumors in adults and 15% of such tumors in children. Cardiac myxoma is usually soft in texture and has a friable or villous surface, which tends to be associated with embolic events. It is also rare for myxoma to be full of calcium and metastatic bone deposits.Case presentation: We herein present a 58-year-old female patient with cardiac space-occupying lesion within the left atrium, and the lesion is lubricous and hard. Her only symptoms were hypertension, dizziness, and chest stuffiness. After surgical resection, we confirmed that the lesion was atrial myxoma by histopathology examination. The patient recovered uneventfully and was discharged. A 2-year follow-up exam showed no evidence of tumor recurrence.Conclusions: Cardiac myxoma is rare and has various clinical manifestations. It is usually friable and has an irregular surface, making embolic manifestations one of the most common complications. Consequently, immediate surgical excision is suggested upon diagnosis. In our case, the patient had a rare type of cardiac myxoma, which had a hard texture and lubricous surface. In our opinion, this case has a low risk of embolism. We prefer elective surgery rather than emergency surgery to perfect the preoperative examination for this kind of patient.

Sign in / Sign up

Export Citation Format

Share Document