scholarly journals P6198Association of heart failure and contrast-induced acute kidney injury on short- and long-term mortality in patients with STEMI undergoing primary PCI

2018 ◽  
Vol 39 (suppl_1) ◽  
Author(s):  
V Zobenica ◽  
D Milasinovic ◽  
Z Mehmedbegovic ◽  
S Zaharijev ◽  
D Jelic ◽  
...  
F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 986 ◽  
Author(s):  
Jennifer A. Schaub ◽  
Chirag R. Parikh

Acute kidney injury is strongly associated with increased mortality and other adverse outcomes. Medical researchers have intensively investigated novel biomarkers to predict short- and long-term outcomes of acute kidney injury in many patient care settings, such as cardiac surgery, intensive care units, heart failure, and transplant. Future research should focus on leveraging this relationship to improve enrollment for clinical trials of acute kidney injury.


2021 ◽  
Vol 50 (6) ◽  
pp. 729-739
Author(s):  
Gianluca Villa ◽  
Faeq Husain-Syed ◽  
Thomas Saitta ◽  
Dario Degl’Innocenti ◽  
Francesco Barbani ◽  
...  

Hemodynamic instability associated with acute renal replacement therapy (aRRT, HIRRT) and/or with acute kidney injury (AKI) is frequently observed in the intensive care unit; it affects patients’ renal recovery, and negatively impacts short- and long-term mortality. A thorough understanding of mechanisms underlying HIRRT and AKI-related hemodynamic instability may allow the physician in adopting adequate strategies to prevent their occurrence and reduce their negative consequences. The aim of this review is to summarize the main alterations occurring in patients with AKI and/or requiring aRRT of those homeostatic mechanisms which regulate hemodynamics and oxygen delivery. In particular, a pathophysiological approach has been used to describe the maladaptive interactions between cardiac output and systemic vascular resistance occurring in these patients and leading to hemodynamic instability. Finally, the potential positive effects of aRRT on these pathophysiological mechanisms and on restoring hemodynamic stability have been described.


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