scholarly journals Multidisciplinary program based in physiotherapy and nutrition in coronary artery disease patients: randomized controlled trial

2021 ◽  
Vol 20 (Supplement_1) ◽  
Author(s):  
E Munoz Gomez ◽  
N Sempere-Rubio ◽  
J Blesa ◽  
P Iglesias ◽  
L Mico ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Heart Rate ◽  
Dietary Intervention ◽  
Eating Habits ◽  
Controlled Trial ◽  
Peak Heart Rate ◽  
Randomized Controlled ◽  
Multidisciplinary Program ◽  
Artery Disease ◽  
Dietary Education

Abstract Funding Acknowledgements Type of funding sources: None. Introduction. The interventions on eating habits and exercise in physiotherapy programs are usually recommended in coronary artery disease (CAD), since they are beneficial to improve physical and nutritional status of patient. Despite this, scarce studies are focused on combined protocols based on high intensity interval training (HIIT) and dietary education in CAD patients with percutaneous coronary intervention (PCI). Purpose The main goal of this study was to compare the effectiveness of a multidisciplinary program based in HIIT, with a program based in dietary education and HIIT (DEHIIT), on eating habits in CAD patients with PCI. Methods. A prospective, randomized controlled trial with blinded outcome assessment was developed. The study was developed at a University research laboratory. 44 participants diagnosed with CAD, aged between 40 and 72 years, were randomly allocated to two treatment groups: HIIT group (HIITG, n = 22) and dietary intervention and HIIT group (DEHIITG, n = 22). The assessment consisted of applying a Food Frequency Questionnaires (FFQ) at baseline and post-intervention. DEHIITG performed a 3-month dietary intervention program combined with 24 HIIT sessions at 85-95% of peak heart rate, whilst HIITG performed a 3-month HIIT sessions at 85-95% of peak heart rate. This study did not receive any funding. No conflict of interest is declared. Results. At the end of the program, when comparing between groups, statistically significant changes were noted. DEHIITG consumed more olive oil (p = 0.021), chicken or turkey (p = 0.039), stir-fried with vegetables (p = 0.033), vegetables (p = 0.003), fish and seafood (p = 0.039), and quantity of commercial juices (p = 0.042), sweets and snacks (p = 0.033). HIITG showed more improvements than DEHIITG in soups and creams consumption (p = 0.042). No adverse events were reported. Conclusions. A dietary intervention with HIIT protocol yields better benefits than only HIIT on eating habits in CAD patients with PCI. Thus, our combined program could be considered a suitable treatment option among these patients.

scholarly journals Effectiveness of a physiotherapy and nutrition program in patients with coronary artery disease: randomized controlled trial

2021 ◽  
Vol 20 (Supplement_1) ◽  
Author(s):  
E Munoz Gomez ◽  
N Sempere-Rubio ◽  
J Blesa ◽  
P Iglesias ◽  
L Mico ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Heart Rate ◽  
Coronary Artery ◽  
Mediterranean Diet ◽  
Dietary Intervention ◽  
Peak Heart Rate ◽  
Group Randomized Trial ◽  
The Mediterranean ◽  
Artery Disease ◽  
Dietary Education

Abstract Funding Acknowledgements Type of funding sources: None. Introduction. Dietary and exercise interventions are effective strategies for improving physical and nutritional status of patients with coronary artery disease (CAD). However, few studies have applied a combined exercise protocol based on high intensity interval training (HIIT) and dietary education in patients with CAD with percutaneous coronary intervention (PCI). Purpose This study researches the effectiveness of a multidisciplinary program based in HIIT with dietary education (DEHIIT) in comparison with only HIIT, on adherence to Mediterranean diet in CAD patients with PCI. Methods. A prospective, assessor-blinded, parallel group, randomized trial was developed. The study was developed at a University research lab. Forty-four adults diagnosed with CAD (between 40 and 72 years), were randomized to receive either combined dietary intervention and HIIT (DEHIIT, n = 22) or only HIIT (HIIT, n = 22). The adherence to the Mediterranean diet was assessed with a 14-item tool of adherence to the Mediterranean diet (MEDAS-14) at baseline and after the intervention. DEHIIT performed a 3-month dietary intervention program combined with 24 HIIT sessions at 85-95% of peak heart rate, whilst HIIT performed a 3-month HIIT sessions at 85-95% of peak heart rate. This study did not receive any funding. No conflict of interest is declared. Results. After three months, regarding to MEDAS-14, DEHIIT increased the fish/seafood consumption significantly (p = 0.001) and decreased the fruit consumption (p = 0.032) and dry fruits (p = 0.006). And, when comparing between groups, DEHIIT obtained significantly more MEDAS-14 score (p = 0.01) and more adherence to dieta mediterránea (p = 0.001). No adverse events were reported. Conclusions. A combined protocol including dietary intervention and HIIT can bring benefits for CAD patients with PCI on adherence to Mediterranean diet in comparison to only HIIT. Consequently, our combined program could be used as a treatment option in the therapeutic approach for these patients.

Water exercise in coronary artery disease patients, effects on heart rate variability, and body composition: A randomized controlled trial

2018 ◽  
Vol 23 (3) ◽  
pp. e1713 ◽  
Author(s):  
Elie Fiogbé ◽  
Rafaela Ferreira ◽  
Márcio Antônio Gonçalves Sindorf ◽  
Silvia Aparecida Tavares ◽  
Keiti Passoni de Souza ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Heart Rate ◽  
Randomized Controlled Trial ◽  
Heart Rate Variability ◽  
Body Composition ◽  
Coronary Artery ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Water Exercise ◽  
Artery Disease

scholarly journals The impact of vildagliptin on the daily glucose profile and coronary plaque stability in impaired glucose tolerance patients with coronary artery disease: VOGUE—A multicenter randomized controlled trial

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hiroyuki Yamamoto ◽  
Akihide Konishi ◽  
Toshiro Shinke ◽  
Hiromasa Otake ◽  
Masaru Kuroda ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Controlled Trial ◽  
Control Group ◽  
Randomized Controlled ◽  
Fibrous Cap ◽  
Multicenter Randomized Controlled Trial ◽  
The Mean ◽  
Artery Disease ◽  
Fibrous Cap Thickness ◽  
The Impact

Abstract Background The impact of reduction in glycemic excursion on coronary plaques remains unknown. This study aimed to elucidate whether a dipeptidyl peptidase 4 inhibitor could reduce the glycemic excursion and stabilize the coronary plaques compared with conventional management in coronary artery disease (CAD) patients with impaired glucose tolerance (IGT). Methods This was a multicenter, randomized controlled trial including CAD patients with IGT under lipid-lowering therapy receiving either vildagliptin (50 mg once a day) or no medication (control group) regarding glycemic treatment. The primary endpoint was changes in the minimum fibrous cap thickness and lipid arc in non-significant native coronary plaques detected by optical coherence tomography at 6 months after intervention. Glycemic variability expressed as the mean amplitude of glycemic excursion (MAGE) measured with a continuous glucose monitoring system was evaluated before and 6 months after intervention. Results A total of 20 participants with 47 lesions were allocated to either the vildagliptin group (10 participants, 22 lesions) or the control group (10 participants, 25 lesions). The adjusted difference of mean changes between the groups was − 18.8 mg/dl (95% confidence interval, − 30.8 to − 6.8) (p = 0.0064) for the MAGE (vildagliptin, − 20.1 ± 18.0 mg/dl vs. control, 2.6 ± 12.7 mg/dl), − 22.8° (− 40.6° to − 5.1°) (p = 0.0012) for the mean lipid arc (vildagliptin, − 9.0° ± 25.5° vs. control, 15.8° ± 16.8°), and 42.7 μm (15.3 to 70.1 μm) (p = 0.0022) for the minimum fibrous cap thickness (vildagliptin, 35.7 ± 50.8 μm vs. control, − 15.1 ± 25.2 μm). Conclusions Vildagliptin could reduce the MAGE at 6 months and may be associated with the decreased lipid arc and increased minimum FCT of the coronary plaques in CAD patients with IGT as compared with the control group. These findings may represent its potential stabilization effect on coronary plaques, which are characteristic in this patient subset. Trial registration Registered in the UMIN clinical trial registry (UMIN000008620), Name of the registry: VOGUE trial, Date of registration: Aug 6, 2012, URL: https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000010058

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