scholarly journals The Isolation of Polygenic Factors Controlling Bristle Score in Drosophila Melanogaster. II. Distribution of Third Chromosome Bristle Effects within Chromosome Sections.

Genetics ◽  
1988 ◽  
Vol 118 (3) ◽  
pp. 445-459
Author(s):  
A E Shrimpton ◽  
A Robertson
Keyword(s):  
Drosophila Melanogaster ◽  
Standard Deviation ◽  
Genetic Factors ◽  
Effective Factors ◽  
Quantitative Characters ◽  
Number Of Factors ◽  
Phenotypic Standard Deviation ◽  
Degree Of Certainty ◽  
Minimum Number ◽  
The Difference

Abstract In the present study an attempt has been made to characterize the genetic ;;factors'' controlling quantitative characters, bristle numbers, in Drosophila melanogaster. A low sternopleural bristle multiple recessive marker third chromosome was used to analyze a high sternopleural third chromosome, in a high sternopleural bristle background. An attempt was made to estimate the minimum number of ;;effective factors'' involved in the difference in bristle score between the tested and marker chromosomes. Apart from sternopleural, scutellar and ocellar bristles, a new character, subprimal bristles, was also scored. The unselected characters were used to help in the factor locations, and an attempt made to detect epistasis. Concentrations of bristle effects were found, as were a few ;factors' of large effect. At least 17 sternopleural bristle factors are required to account for the difference in bristle score between the high tested third chromosome and the low tester third chromosome. There was an ascertainment problem for polygenes with effects of less than about 0.6 phenotypic standard deviation. Only an estimate of the minimum number of factors and approximate locations can be given with any degree of certainty. The results are compatible with the hypothesis (among others) that quantitative characters are under the control of a few major genes supported by numerous genes with smaller effect.

THE MINIMUM NUMBER OF GENES CONTRIBUTING TO QUANTITATIVE VARIATION BETWEEN AND WITHIN POPULATIONS

Genetics ◽  
1981 ◽  
Vol 99 (3-4) ◽  
pp. 541-553
Author(s):  
Russell Lande
Keyword(s):  
Genetic Factors ◽  
Inbred Lines ◽  
Quantitative Character ◽  
Standard Errors ◽  
Large Samples ◽  
Evolutionary Changes ◽  
Number Of Genes ◽  
Minimum Number ◽  
The Difference ◽  
Two Populations

ABSTRACT A procedure is outlined for estimating the minimum number of freely segregating genetic factors, nE,contributing to the difference in a quantitative character between two populations that have diverged by artificial or natural selection. If certain simple criteria are satisfied approximately on an appropriate scale of measurement, nEcan be estimated by comparing the phenotypic means and variances in the two parental populations and in their F1 and F2 hybrids (and backcrosses). This generalizes the method of WRIGHtTo genetically heterogeneous (or wild) parental populations, as well as inbred lines. Standard errors of the estimates are derived for large samples. The minimum number of genes involved in producing a large difference between populations in a quantitative trait is typically estimated to be about 5 or IO, with occasional values up to 20. This strongly supports the neo-Darwinian theory that large evolutionary changes usually occur by the accumulation of multiple genetic factors with relatively small effects.

Testing for Asymmetrical Gene Flow in aDrosophila melanogasterBody-Size Cline

Genetics ◽  
2003 ◽  
Vol 165 (2) ◽  
pp. 667-673 ◽  
Author(s):  
W Jason Kennington ◽  
Julia Gockel ◽  
Linda Partridge
Keyword(s):  
Drosophila Melanogaster ◽  
Gene Flow ◽  
Body Size ◽  
Genetic Parameter ◽  
Good Evidence ◽  
Microsatellite Data ◽  
Eastern Australia ◽  
The Difference ◽  
Two Populations ◽  
Private Alleles

AbstractAsymmetrical gene flow is an important, but rarely examined genetic parameter. Here, we develop a new method for detecting departures from symmetrical migration between two populations using microsatellite data that are based on the difference in the proportion of private alleles. Application of this approach to data collected from wild-caught Drosophila melanogaster along a latitudinal body-size cline in eastern Australia revealed that asymmetrical gene flow could be detected, but was uncommon, nonlocalized, and occurred in both directions. We also show that, in contrast to the findings of a previous study, there is good evidence to suggest that the cline experiences significant levels of gene flow between populations.

HYPOCHROMIC MICROCYTIC ANEMIA OF INFANCY: IRON DEPLETION AS A FACTOR

PEDIATRICS ◽  
1956 ◽  
Vol 18 (6) ◽  
pp. 959-978
Author(s):  
Hugh W. Josephs
Keyword(s):  
Iron Deficiency ◽  
Severe Infection ◽  
Microcytic Anemia ◽  
Severe Anemia ◽  
Iron Depletion ◽  
Hypochromic Microcytic Anemia ◽  
Premature Babies ◽  
Number Of Factors ◽  
The Difference ◽  
Insight Into

In this work the author has attempted to gain insight into the significance of iron depletion by the use of 4 simple calculations, justification for which is found in recent articles. These are: (a) iron with which the infant is born; (b) iron retained from the food; (c) iron being used by the tissues and therefore unavailable for hemoglobin, and (d) iron combined with the total mass of hemoglobin. With these 4 figures it is possible to estimate the iron still potentially available for use (the "reserves" or "stones"). When the difference between a + b and c + d has reached about zero, depletion is considered to exist. The following characteristics of depletion may be emphasized: Depletion is the result of gain in weight and maximum possible usage of iron. It is therefore a normal result of growth and need not be associated with anemia. As soon as depletion has occurred, the organism is thereafter dependent on current absorption of iron. This is ordinarily sufficient, even with a diet of milk alone, to maintain an adequate concentration of hemoglobin after about 8 to 10 months of age. Severe anemia due to depletion alone is practically confined to premature babies whose relative gain in weight is rapid. Severe anemia in other than premature babies is the result of a number of factors by which iron becomes unavailable or is actually diverted from hemoglobin to storage. Response to iron medication is considerably better in infants with depletion than in those in whom some factor is present that interferes with iron utilization, and which is not connected by the mere giving of iron. The dependence on current absorption, whether the result of depletion or non-availability, introduces a certain precariousness which is apparently characteristic of this time of life. The organism gets along from day to day if nothing happens, but may not be able to meet an emergency, whether this appears as a rapid gain in weight, or a necessity to repair damage done by severe infection. If we consider iron deficiency as the cause of anemia, we can think of deficiency as due to a number of factors of which depletion is only one. The development and characteristics of depletion have been considered in this paper; other factors in iron deficiency will be considered in subsequent papers.

scholarly journals Intrinsic linking and knotting in tournaments

2019 ◽  
Vol 28 (12) ◽  
pp. 1950076
Author(s):  
Thomas Fleming ◽  
Joel Foisy
Keyword(s):  
Directed Graph ◽  
Upper Bound ◽  
Directed Edge ◽  
Undirected Graphs ◽  
Oriented Cycle ◽  
Minimum Number ◽  
The Difference

A directed graph [Formula: see text] is intrinsically linked if every embedding of that graph contains a nonsplit link [Formula: see text], where each component of [Formula: see text] is a consistently oriented cycle in [Formula: see text]. A tournament is a directed graph where each pair of vertices is connected by exactly one directed edge. We consider intrinsic linking and knotting in tournaments, and study the minimum number of vertices required for a tournament to have various intrinsic linking or knotting properties. We produce the following bounds: intrinsically linked ([Formula: see text]), intrinsically knotted ([Formula: see text]), intrinsically 3-linked ([Formula: see text]), intrinsically 4-linked ([Formula: see text]), intrinsically 5-linked ([Formula: see text]), intrinsically [Formula: see text]-linked ([Formula: see text]), intrinsically linked with knotted components ([Formula: see text]), and the disjoint linking property ([Formula: see text]). We also introduce the consistency gap, which measures the difference in the order of a graph required for intrinsic [Formula: see text]-linking in tournaments versus undirected graphs. We conjecture the consistency gap to be nondecreasing in [Formula: see text], and provide an upper bound at each [Formula: see text].

scholarly journals “Childhood Obesity its Factors, Complications and Impact on Overall Health in Children”

2021 ◽  
pp. 1-5
Author(s):  
Asma Saghir Khan
Keyword(s):  
Physical Activity ◽  
Childhood Obesity ◽  
Health Care Professionals ◽  
Genetic Factors ◽  
Overweight And Obesity ◽  
Family Influences ◽  
Childhood Overweight And Obesity ◽  
Number Of Factors ◽  
Obesity And Overweight

Childhood, overweight and obesity are increasingly significant problems, and ones that are likely to endure and to have long term adverse influences on the health of individuals and populations unless action is taken to reverse the trend. A number of factors have been suggested as contributing to the development of childhood obesity. These include genetic factors, decreasing levels of physical activity, increased time spent in sedentary behavior and changes in diet. In addition, lifestyle factors, including family influences, changes in society and media advertising, have been associated with the increasing incidence of obesity and overweight in childhood. To address the problem, health care professionals should incorporate appropriate screening in their child practice. Comprehensive assessment of children who are, or who are at risk of becoming, obese is also necessary

scholarly journals Synthesis of Plans to Increase the Results of Ordinary National Education Test by All-Round Tutoring Process for Primary School Grade 6

2021 ◽  
Vol 14 (2) ◽  
pp. 63
Author(s):  
Nuttakan Pakprod ◽  
Kanokrat Jirasatjanukul ◽  
Damrong Tumthong ◽  
Prapa Amklad ◽  
Wipa Lekchom
Keyword(s):  
Standard Deviation ◽  
Primary School ◽  
Target Group ◽  
Educational Testing ◽  
School Grade ◽  
National Education ◽  
Standard Deviations ◽  
The Difference ◽  
High Level ◽  
Basic Level

The objective of this research is to study the results of activities to increase the scores of Ordinary National Education Test. Cluster; teachers of Phetchaburi Rajabhat University comparing the results of Ordinary National Education Test in 2017-2018 and studying the satisfaction of the activities. The target group is 49 schools in Phetchaburi and Prachuap Khiri Khan Provinces, data were analyzed using mean and standard deviation. The study found that the difference of the scores of the Ordinary National Education Test was higher in 32 schools and there is a difference in scores of Ordinary National Education Test tests lower by 2 schools, representing 94.12, with the satisfaction of the participation in the activity of increasing the basic educational testing at the basic level is at a high level with an average of 4.22, standard deviations 0.73, which the participants are satisfied with the process. The process of organizing activities was at the highest with an average of 4.28, standard deviations 0.76 and continues organizing activities to increase the scores of Ordinary National Education Test.

scholarly journals On L h , k -Labeling Index of Inverse Graphs Associated with Finite Cyclic Groups

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
K. Mageshwaran ◽  
G. Kalaimurugan ◽  
Bussakorn Hammachukiattikul ◽  
Vediyappan Govindan ◽  
Ismail Naci Cangul
Keyword(s):  
Cyclic Group ◽  
Upper Bound ◽  
Labeling Index ◽  
Positive Difference ◽  
Cyclic Groups ◽  
Finite Cyclic Group ◽  
Minimum Number ◽  
The Difference ◽  
Radio Labeling

An L h , k -labeling of a graph G = V , E is a function f : V ⟶ 0 , ∞ such that the positive difference between labels of the neighbouring vertices is at least h and the positive difference between the vertices separated by a distance 2 is at least k . The difference between the highest and lowest assigned values is the index of an L h , k -labeling. The minimum number for which the graph admits an L h , k -labeling is called the required possible index of L h , k -labeling of G , and it is denoted by λ k h G . In this paper, we obtain an upper bound for the index of the L h , k -labeling for an inverse graph associated with a finite cyclic group, and we also establish the fact that the upper bound is sharp. Finally, we investigate a relation between L h , k -labeling with radio labeling of an inverse graph associated with a finite cyclic group.

scholarly journals Association between family history and the onset age of essential hypertension in Han population in Shanghai China

2019 ◽  
Author(s):  
li anle ◽  
Qian Peng ◽  
Yue Qin Shao ◽  
Yi Ying Zhang ◽  
Fang Xiang
Keyword(s):  
Essential Hypertension ◽  
Family History ◽  
Genetic Factors ◽  
Nuclear Family ◽  
Age Of Onset ◽  
Control Group ◽  
Case Group ◽  
Onset Age ◽  
Han Population ◽  
The Difference

Abstract Importance Genetic factors are important influencing factors of essential hypertension, and family history (FH) is an important marker of genetic factors. Objective To explore the association between family history and the onset age of essential hypertension in Han population in Shanghai China. Methods According to l:l matched pairs design，342 precursor of hypertension and 342 controls were selected and investigate their nuclear family members in the case-control study. The diagnostic information of hypertension in all relatives of these two groups was investigated. The method of genetic epidemiology research was used to explore the effect of family history. Results The average prevalence of hypertension was 23.32%. The prevalence of hypertension of first-degree relatives was 33.99%; the prevalence of second- degree relatives was 17.60%; the prevalence of third-degree relatives was 13.51%. All prevalence of hypertension of case group relatives were significantly higher than that of control group relatives. The average onset age in population with positive FH is 48.74±11.16 years old, and the average onset age in population with negative FH is 54.38±9.87 years old. The difference about two FH groups showed statistically significant (t=4.589, P<0.001). The average onset age of offspring with father, mother, grandpa, grandma, maternal grandpa or maternal grandma positive was respectively 48.42± 11.16, 49.16±11.12, 39.55±11.95, 39.88±11.90, 43.67±9.77 or 43.64±10.21 years old; and the average onset age of children with father, mother, grandpa, grandma, maternal grandpa or maternal grandma negative was respectively 51.90± 10.81, 51.17±11.04, 51.07±10.59, 51.08±10.60, 50.50±11.09 or 50.57±11.06 years old. The difference about two groups showed statistically significant. Conclusion Family history has a positive effect on the occurrence of hypertension, and lead to earlier age of onset of offspring. The effects are different among parent and grandparent in Han in Shanghai China.

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