Self-Rated Health and Depressive Symptoms in Patients With End-Stage Renal Disease and Their Spouses: A Longitudinal Dyadic Analysis of Late-Life Marriages

Abstract Background Research suggests that patients with end stage renal disease undergoing hemodialysis have a higher rate of depression and dietary non adherence leading to hospitalization and mortality. The purpose of this review was to synthesize the quantitative evidence on the relationship between depressive symptoms and dietary non adherence among end stage renal disease (ESRD) patients receiving hemodialysis. Methods A systematic review was undertaken. Three electronic databases were searched including PubMed, CINHAL and Web of Science. Only quantitative studies published between 2001 and 2016 were included in the review. Result A total of 141 publications were reviewed during the search process and 28 articles that fulfilled the inclusion criteria were included in the review. Eleven studies (39.3%) reported on the prevalence of depressive symptoms or depression and its effect on patient outcomes. Ten studies (35.7%) focused on dietary adherence/non adherence in patients with ESRD and the remaining seven (25%) articles were descriptive studies on the relationship between depressive symptoms and dietary non adherence in patients with ESRD receiving hemodialysis. The prevalence of depressive symptoms and dietary non adherence ranged as 6–83.49% and from 41.1–98.3% respectively. Decreased quality of life & increased morbidity and mortality were positively associated with depressive symptoms. Other factors including urea, hemoglobin, creatinine and serum albumin had also association with depressive symptoms. Regarding dietary non adherence, age, social support, educational status, behavioral control and positive attitudes are important factors in ESRD patients receiving hemodialysis. Having depressive symptoms is more likely to increase dietary non adherence. Conclusion Depressive symptoms and dietary non adherence were highly prevalent in patients with end stage renal disease receiving hemodialysis therapy. Nearly all of the articles that examined the relationship between depressive symptoms and dietary non adherence found a significant association. Future research using experimental or longitudinal design and gold standard measures with established cut-points is needed to further explain the relationship.

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Nonpharmacological Interventions for Depressive Symptoms in End-Stage Renal Disease: A Systematic Review

Western Journal of Nursing Research ◽

10.1177/0193945919857540 ◽

2019 ◽

Vol 42 (6) ◽

pp. 462-473

Author(s):

Xin Wen ◽

Yu Wang ◽

Qiuge Zhao ◽

Hongrui Zhang ◽

Huage Shi ◽

...

Keyword(s):

Depressive Symptoms ◽

Renal Disease ◽

End Stage Renal Disease ◽

Large Scale ◽

Psychological Intervention ◽

Cochrane Library ◽

Stage Renal Disease ◽

End Stage ◽

The Cochrane Library

Depressive symptoms are common in patients with end-stage renal disease, which can affect treatment and prognosis. We aimed to evaluate the effects of nonpharmacological interventions for depressive symptoms in end-stage renal disease. Eligible studies were identified using PubMed, Web of Science, the Cochrane Library, Embase, and PsycNET (up to March 2019). We identified 24 studies including 1,376 patients. We found that psychological intervention (−0.60, 95% confidence interval [CI] = [–0.87, –0.33]), exercise (−1.13, 95% CI = [–1.56, –0.69]), and manual acupressure (−0.26, 95% CI = [–0.50, 0.03]) were associated with a significant effect on depressive symptoms. However, few studies reported adverse events, and conclusions about safety should be drawn cautiously. While the available data show that nonpharmacological interventions are potential strategies to alleviate depressive symptoms of patients with end-stage renal disease, recommendation of the most efficacious interventions for this population will require future randomized controlled trials with large-scale, long-term intervention.

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Depression in Late-Life patients with End-Stage Renal Disease under Online-Haemodiafiltration is Associated with Low Social Support, Muscular Mass and Creatinine Serum Levels

Journal of Clinical Nephrology and Renal Care ◽

10.23937/2572-3286.1510007 ◽

2016 ◽

Vol 2 (1) ◽

Cited By ~ 2

Author(s):

Leonilde Amado

Keyword(s):

Social Support ◽

Renal Disease ◽

End Stage Renal Disease ◽

Late Life ◽

Serum Levels ◽

Stage Renal Disease ◽

End Stage

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Quality of life and depressive symptoms in patients with major depression and end-stage renal disease: A matched-pair study

Journal of Psychosomatic Research ◽

10.1016/j.jpsychores.2006.04.011 ◽

2006 ◽

Vol 61 (5) ◽

pp. 731-734 ◽

Cited By ~ 16

Author(s):

Marcelo T. Berlim ◽

Betina S. Mattevi ◽

Anne Paola G. Duarte ◽

Fernando S. Thomé ◽

Elvino J.G. Barros ◽

...

Keyword(s):

Quality Of Life ◽

Depressive Symptoms ◽

Major Depression ◽

Renal Disease ◽

End Stage Renal Disease ◽

Matched Pair ◽

Stage Renal Disease ◽

End Stage

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Comparison of pre- and post-hemodialysis PHQ-9 depression scores in patients with end-stage renal disease: A cross-sectional study

The International Journal of Psychiatry in Medicine ◽

10.1177/0091217420973489 ◽

2020 ◽

pp. 009121742097348

Author(s):

Izzat AlAwwa ◽

Sarah Ibrahim ◽

Ahmad Obeid ◽

Nadeen Alfraihat ◽

Reham Al-Hindi ◽

...

Keyword(s):

Depressive Symptoms ◽

Renal Disease ◽

End Stage Renal Disease ◽

Maintenance Hemodialysis ◽

Cross Sectional ◽

Symptoms Of Depression ◽

Significant Difference ◽

Before And After ◽

Stage Renal Disease ◽

End Stage

Objectives An overlap between the somatic symptoms of depression and those of uremia seen in end-stage renal disease (ESRD) patients may affect the diagnosis of depression. This study aims to evaluate the effect of hemodialysis on the diagnosis of depression among patients on maintenance hemodialysis as dialysis diminishes the uremic symptoms, and to compare depression scores before and after dialysis. Methods This was a cross-sectional analytic study conducted from November 2018 through April 2019, in three tertiary hospitals. Consenting participants aged 18 years or older, who had received hemodialysis for at least three months were included. The Patient Health Questionnaire (PHQ-9) tool was used to collect patients’ data and to identify symptoms of depression Pre- and post-hemodialysis. Depression scores were compared using the paired sample Wilcoxon rank test or the McNemar test, where appropriate. Results Overall, 163 participants were enrolled in the study. The average age of the participants was 56.5 years old, whereas 44.8% were females. The prevalence of depressive symptoms before hemodialysis was 48.5%, with prevalence of mild, moderate and moderately severe of 34.4%, 11.7% and 2.5%, respectively. On the other hand, the prevalence of depressive symptoms after hemodialysis was 46.6% with 36.8%, 9.2% and 0.6% of the participants reporting mild, moderate and moderately severe symptoms, respectively. We found no significant difference in depression scores before and after dialysis (p-values > 0.05). Conclusion Our study supports the fact that the prevalence of depression is high among patients with ESRD on maintenance hemodialysis. We didn’t find a significant difference in depression scores among hemodialysis patients before and after dialysis, with negligible effect of uremic symptoms on the diagnosis of depression. We suggest adopting routine screening of depression among this high-risk group of patients.

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Depressive symptomatology and treatment in patients with end-stage renal disease

Psychological Medicine ◽

10.1017/s0033291700013076 ◽

1987 ◽

Vol 17 (1) ◽

pp. 185-190 ◽

Cited By ~ 25

Author(s):

Barry A. Hong ◽

Marc D. Smith ◽

Alan M. Robson ◽

Richard D. Wetzel

Keyword(s):

Depressive Symptoms ◽

Major Depression ◽

Renal Disease ◽

Depressed Patient ◽

End Stage Renal Disease ◽

Depressive Symptomatology ◽

Adult Population ◽

Structured Interview ◽

Stage Renal Disease ◽

End Stage

SynopsisA sample of 60 patients selected at random from an adult population of 419 patients with end-stage renal disease was assessed for major depression. Diagnoses were based on a structured interview using DSM-III criteria. Eighteen patients (30%) met criteria for a major depression on a lifetime basis. In addition, depressive symptoms and treatment for each depressed patient are reported.

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