scholarly journals Insular and Hippocampal Connectivity Is Associated With Perceived Financial Exploitation in Older Adults

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 515-515
Author(s):  
Gali Weissberger ◽  
Laura Mosqueda ◽  
Annie Nguyen ◽  
Jenna Axelrod ◽  
Patricia Boyle ◽  
...  
Keyword(s):  
Older Adults ◽  
Temporal Lobe ◽  
Parietal Lobe ◽  
Occipital Cortex ◽  
Frontal Pole ◽  
Financial Exploitation ◽  
Economic Decision Making ◽  
The Right ◽  
Cognitively Intact ◽  
Left Insula

Abstract Little is known about the neural correlates of financial exploitation (FE) in older adults. Cognitively-intact older adults who self-reported a history of FE (N=19; M age=69.84, SD=13.06) and demographically-matched non-FE older adults (N=16; M age=65.13, SD=8.48) underwent resting-state fMRI. Predefined regions of interest were prescribed using the Harvard-Oxford atlas for their involvement in tasks of economic decision making: insula, hippocampus, and the medial prefrontal cortex (mPFC). Analyses adjusted for age, education, sex, and MoCA scores; groups did not differ on these factors. Clusters were FDR-corrected with a threshold of p<0.05 (voxel threshold p<0.005), two-tailed. Compared to the non-FE group, the FE group exhibited greater functional connectivity (FC) between the right insula and left temporal lobe regions (t(29)= -4.81), and between the left insula and right temporal lobe regions (t(29)= -5.78). The FE group showed less FC between the left insula and two clusters in the right lateral occipital cortex (t(29)= 5.18) and left cerebellum (t(29)= 4.68). Additionally, FE was associated with greater FC between the right hippocampus and five clusters spanning the right temporal lobe, parietal lobe, and frontal pole (ts(29)= -4.11 to -4.51), and less FC between the right hippocampus and three clusters spanning the bilateral caudate and the left intracalcarine cortex (ts(29)= 4.76-6.03). Groups did not differ in FC patterns with the mPFC. Results suggest that FE is associated with whole-brain FC differences involving the insula and hippocampus among cognitively-intact older adults.

Post-Stimulation Effect of Electroacupuncture at Yintang (EX-HN3) and GV20 on cerebral functional regions in healthy volunteers: A resting functional MRI study

2012 ◽  
Vol 30 (4) ◽  
pp. 307-315 ◽  
Author(s):  
Yu Zheng ◽  
Shanshan Qu ◽  
Na Wang ◽  
Limin Liu ◽  
Guanzhong Zhang ◽  
...  
Keyword(s):  
Frontal Lobe ◽  
Temporal Lobe ◽  
Parietal Lobe ◽  
Occipital Lobe ◽  
Cingulate Gyrus ◽  
Left Frontal Lobe ◽  
Posterior Cingulate Gyrus ◽  
Functional Regions ◽  
Limbic Lobe ◽  
The Right

Objective The aim of the present work was to observe the activation/deactivation of cerebral functional regions after electroacupuncture (EA) at Yintang (EX-HN3) and GV20 by functional MRI (fMRI). Design A total of 12 healthy volunteers were stimulated by EA at Yintang and GV20 for 30 min. Resting-state fMRI scans were performed before EA, and at 5 and 15 min after needle removal. Statistical parametric mapping was used to preprocess initial data, and regional homogeneity (ReHo) and amplitude of low-frequency fluctuation (ALFF) were analysed. Results ReHo at 5 min post stimulation showed increases in the left temporal lobe and cerebellum and decreases in the left parietal lobe, occipital lobe and right precuneus. At 15 min post stimulation, ReHo showed increases in the left fusiform gyrus; lingual gyrus; middle temporal gyrus; postcentral gyrus; limbic lobe; cingulate gyrus; paracentral lobule; cerebellum, posterior lobe, declive; right cuneus and cerebellum, anterior lobe, culmen. It also showed decreases in the left frontal lobe, parietal lobe, right temporal lobe, frontal lobe, parietal lobe and right cingulate gyrus. ALFF at 5 min post stimulation showed increases in the right temporal lobe, but decreases in the right limbic lobe and posterior cingulate gyrus. At 15 min post stimulation ALFF showed increases in the left frontal lobe, parietal lobe, occipital lobe, right temporal lobe, parietal lobe, occipital lobe and cerebellum, but decreases in the left frontal lobe, anterior cingulate gyrus, right frontal lobe and posterior cingulate gyrus. Conclusions After EA stimulation at Yintang and GV20, which are associated with psychiatric disorder treatments, changes were localised in the frontal lobe, cingulate gyrus and cerebellum. Changes were higher in number and intensity at 15 min than at 5 min after needle removal, demonstrating lasting and strong after-effects of EA on cerebral functional regions.

Neuropsychological Profiles of Adults Who Report “Sudden Remembering” of Early Childhood Memories: Implications for Claims of Sex Abuse and Alien Visitation/Abduction Experiences

1992 ◽  
Vol 75 (1) ◽  
pp. 259-266 ◽  
Author(s):  
M. A. Persinger
Keyword(s):  
Early Childhood ◽  
Temporal Lobe ◽  
Parietal Lobe ◽  
New Age ◽  
Childhood Memories ◽  
Sex Abuse ◽  
Alien Abduction ◽  
Neuropsychological Assessments ◽  
The Right ◽  
New Age Religion

Six adults, who had recently experienced sudden recall of preschool memories of sex abuse or alien abduction/visitation, were given complete neuropsychological assessments. All experiences “emerged” when hypnosis was utilized within a context of sex abuse or New Age religion and were followed by reduction in anxiety. As a group, these subjects displayed significant ( T > 70) elevations of childhood imaginings, complex partial epileptic-like signs, and suggestibility. Neuropsychological data indicated right frontotemporal anomalies and reduced access to the right parietal lobe. MMPI profiles were normal. The results support the hypothesis that enhanced imagery due to temporal lobe lability within specific contexts can facilitate the creation of memories; they are strengthened further if there is also reduction in anxiety.

Cerebral Blood Flow and Volume in Symptom-Free Migraineurs: a SPECT Study

1990 ◽  
Vol 29 (05) ◽  
pp. 210-214 ◽  
Author(s):  
G. L. Turco ◽  
G. Castellano ◽  
W. Liboni ◽  
V. Podio ◽  
G. Chianale ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Gamma Camera ◽  
Parietal Lobe ◽  
Diagnostic Yield ◽  
Occipital Lobe ◽  
Occipital Cortex ◽  
Nuclear Data ◽  
The Right ◽  
Ct And Mri

Both CBF and CBV were evaluated by gamma-camera SPECT in 14 patients with classic migraine, all studied while symptom-free. Nuclear data were correlated with CT and MRI. A decreased regional CBF was observed in 13 of the 14 patients. The decreased perfusion was localized in the frontal lobe in 6 patients, the temporal lobe in one, the parietal lobe in 11 and the occipital lobe in 5 patients. The parieto-occipital cortex was involved more often than the frontal cortex; the association of hypoperfusion with parieto-occipital cortex was quite high. The right parieto-occipital regions were affected more often than the left ones. Regional CBV was increased in 8 patients. There was good topographical concordance between decreased CBF and increased CBV, but the increase of CBV was in general more evident at the periphery of the hypoperfusion. It is of interest that the only patient with a normal CBF study had a pathological CBV study. Apparently, CBF derangements are very common in symptom-free patients with classic migraine, a CBF decrease being often accompanied by a CBV increase. In these patients both CT and MRI have a lower diagnostic yield than SPECT.

scholarly journals Right Superior Temporal Gyrus Altered Functional Activity in Patients With Definite Vestibular Migraine

2022 ◽  
Author(s):  
Xu Yang ◽  
Zhe-Yuan Li ◽  
Li-Hong Si ◽  
Bo Shen ◽  
Xia Ling
Keyword(s):  
Frontal Lobe ◽  
Temporal Lobe ◽  
Functional Activity ◽  
Cluster Size ◽  
Parietal Lobe ◽  
Brain Activity ◽  
Superior Temporal Gyrus ◽  
Vestibular Migraine ◽  
Middle Temporal Gyrus ◽  
The Right

Abstract The study aimed to investigate resting-state functional brain activity alterations in patients with definite vestibular migraine (dVM). Seventeen patients with dVM, 8 patients with migraine, 17 health controls (HCs) were recruited. The amplitude of low frequency fluctuation (ALFF), fractional ALFF (fALFF) and regional homogeneity (ReHo) were calculated to observe the changes in spontaneous brain activity. Then brain regions with altered fALFF were selected for seed-based functional connectivity analysis. Compared with HCs, VM patients showed significantly increased ALFF values in the right temporal lobe (Cluster size = 91 voxels, P=0.002, FWE corrected), and significantly increased ReHo values in the right superior temporal gyrus (STG), middle temporal gyrus (MTG) and inferior temporal gyrus (ITG) (Cluster size = 136 voxels, P=0.013, FWE corrected). Compared with patients with migraine, patients with VM showed significantly increased fALFF values in the right parietal lobe (Cluster size = 43 voxels, P=0.011, FWE corrected) and right frontal lobe (Cluster size =36 voxels, P=0.026, FWE corrected), significantly increased ReHo values in the right thalamus (Cluster size = 92 voxels, P=0.043, FWE corrected). Our findings documented that patients with VM showed enhanced spontaneous functional activity in the right temporal lobe (STG, MTG, and ITG) compared with HCs, and increased spontaneous activity in the right parietal lobe-frontal lobe-thalamus compared with patients with migraine. Patients with VM and migraine both had altered brain function, but the regions involved are different.

scholarly journals Frailty and Perceived Financial Exploitation: Findings from the Finance, Cognition, and Health in Elders Study

2020 ◽  
Vol 6 ◽  
pp. 233372142097107
Author(s):  
Jenna Axelrod ◽  
Laura Mosqueda ◽  
Gali H. Weissberger ◽  
Annie L. Nguyen ◽  
Patricia A. Boyle ◽  
...  
Keyword(s):  
Older Adults ◽  
Old Age ◽  
Intervention Programs ◽  
Physical Frailty ◽  
Financial Exploitation ◽  
Post Hoc ◽  
Cognitively Intact

Objective: Many older adults who are cognitively intact experience financial exploitation (FE), and the reasons for this are poorly understood. Methods: Data were gathered from 37 older adults ( M age = 69.51, M education = 15.89, 62% female) from the Finance, Cognition, and Health in Elders Study (FINCHES). Twenty-four older adults who self-reported FE were demographically-matched according to age, education, race, and MoCA performance to thirteen older adults who denied experiencing FE. Participants completed the Tilburg Frailty Inventory. Results: FE participants reported greater total frailty ( t = 2.06, p = .04) when compared to non-FE participants. Post-hoc analyses revealed that FE participants endorsed greater physical frailty ( U = 89, p = .03), specifically poorer sensory functioning (hearing and vision). Discussion: Findings suggest frailty is associated with FE in old age and may represent a target for intervention programs for the financial wellbeing of older adults.

scholarly journals Individual differences in theta-band oscillations in a spatial memory network revealed by EEG predict rapid place learning

2020 ◽  
Author(s):  
Markus Bauer ◽  
Matthew G. Buckley ◽  
Tobias Bast
Keyword(s):  
Individual Differences ◽  
Spatial Memory ◽  
Temporal Lobe ◽  
Occipital Cortex ◽  
Place Learning ◽  
Theta Oscillations ◽  
Theta Band ◽  
Eeg Recordings ◽  
The Right ◽  
Encoding And Retrieval

AbstractSpatial memory has been closely related to the medial temporal lobe (MTL), and theta-oscillations are thought to play a key role. However, it remains difficult to investigate medio-temporal lobe (MTL) activation related to spatial memory with non-invasive electrophysiological methods in humans.Here, we combined the virtual delayed-matching-to-place (DMP) task, reverse-translated from the watermaze DMP task in rats, with high-density electroencephalography (EEG) recordings. Healthy young volunteers performed this computerised task in a virtual circular arena, which contained a hidden target whose location moved to a new place every four trials, allowing the assessment of rapid memory formation.Using behavioural measures as predictor variables for source reconstructed frequency specific EEG power, we found that inter-individual differences in ‘search preference’ during ‘probe trials’, a measure of 1-trial place learning known from rodent studies to be particularly hippocampus dependent, correlated predominantly with distinct theta-band oscillations (approx. 7 Hz), particularly in the right temporal lobe, the right striatum and inferior occipital cortex or cerebellum. Notably, this pattern was found with very high consistency during both encoding and retrieval/expression, but not in control analyses and could not be explained by motor confounds. Alpha-activity in sensorimotor and parietal cortex contralateral to the hand used for navigation also correlated with search preference, which likely reflected movement-related factors associated with task performance.Relating inter-individual differences in ongoing brain activity to behaviour in a continuous rapid place learning task that is suitable for a variety of populations, we could demonstrate that memory related theta-band activity in temporal lobe can be measured with EEG recordings, revealing a presumed network of MTL, striatum and cerebellum and/or inferior occipital cortex that may interact through theta oscillations. This approach holds great potential for further studies investigating the interactions within this network during encoding and retrieval, as well as neuromodulatory impacts and age-related changes.

scholarly journals Brain activity in the right-frontal pole and lateral occipital cortex predicts successful post-operatory outcome after surgery for anterior glenoumeral instability

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Davide Zanchi ◽  
Gregory Cunningham ◽  
Alexandre Lädermann ◽  
Mehmet Ozturk ◽  
Pierre Hoffmeyer ◽  
...  
Keyword(s):  
Brain Activity ◽  
Occipital Cortex ◽  
Frontal Pole ◽  
The Right ◽  
Lateral Occipital Cortex

What face familiarity feelings say about the lateralization of specific entities within the core system

2019 ◽  
Vol 42 ◽  
Author(s):  
Guido Gainotti
Keyword(s):  
Temporal Lobe ◽  
Memory System ◽  
Core System ◽  
The Core ◽  
Memory Traces ◽  
Specific Memory ◽  
Target Article ◽  
Temporal Structures ◽  
The Right

Abstract The target article carefully describes the memory system, centered on the temporal lobe that builds specific memory traces. It does not, however, mention the laterality effects that exist within this system. This commentary briefly surveys evidence showing that clear asymmetries exist within the temporal lobe structures subserving the core system and that the right temporal structures mainly underpin face familiarity feelings.

Neural Underpinnings of Numerical and Spatial Cognition: An fMRI Meta-Analysis of Brain Regions Associated with Symbolic Number, Arithmetic, and Mental Rotation

2019 ◽  
Author(s):  
Zachary Hawes ◽  
H Moriah Sokolowski ◽  
Chuka Bosah Ononye ◽  
Daniel Ansari
Keyword(s):  
Mental Rotation ◽  
Parietal Lobe ◽  
Meta Analysis ◽  
Likelihood Estimation ◽  
Brain Regions ◽  
Angular Gyrus ◽  
Number Representation ◽  
Neural Underpinnings ◽  
The Right ◽  
Symbolic Number

Where and under what conditions do spatial and numerical skills converge and diverge in the brain? To address this question, we conducted a meta-analysis of brain regions associated with basic symbolic number processing, arithmetic, and mental rotation. We used Activation Likelihood Estimation (ALE) to construct quantitative meta-analytic maps synthesizing results from 86 neuroimaging papers (~ 30 studies/cognitive process). All three cognitive processes were found to activate bilateral parietal regions in and around the intraparietal sulcus (IPS); a finding consistent with shared processing accounts. Numerical and arithmetic processing were associated with overlap in the left angular gyrus, whereas mental rotation and arithmetic both showed activity in the middle frontal gyri. These patterns suggest regions of cortex potentially more specialized for symbolic number representation and domain-general mental manipulation, respectively. Additionally, arithmetic was associated with unique activity throughout the fronto-parietal network and mental rotation was associated with unique activity in the right superior parietal lobe. Overall, these results provide new insights into the intersection of numerical and spatial thought in the human brain.

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