scholarly journals Hearing Loss and Frailty Among Older Adults: The ARIC Neurocognitive Study

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 811-811
Author(s):  
Nicholas Reed ◽  
Emmanuel Garcia-Morales ◽  
Priya Palta ◽  
Frank Lin ◽  
Josef Coresh ◽  
...  
Keyword(s):  
Older Adults ◽  
Hearing Loss ◽  
Pure Tone ◽  
Walking Speed ◽  
Pure Tone Audiometry ◽  
Future Research ◽  
Atherosclerosis Risk In Communities ◽  
Atherosclerosis Risk ◽  
Aric Study ◽  
The Impact

Abstract Hearing Loss (HL) is common among older adults and is associated with factors (e.g., walking speed and social isolation) that may mediate an association with frailty. In the Atherosclerosis Risk in Communities (ARIC) study, frailty was defined as a composite variable (unintentional weight loss, energy expenditure, walking speed, low energy, and grip strength) while HL was measured using pure-tone audiometry. Among, 3179 participants in 2015-2017, 251 (7.9%) were frail. In a model adjusted for demographic and clinical risk factors, mild HL (n=1263; Odds Ratio[OR]=1.42; 95%Confidence Interval[CI]=1.01-2.01) and moderate HL (n=854; OR=1.67; 95%CI=1.09-2.55) were associated with higher odds of frailty relative to those without HL (n=1063). Among participants who completed an ARIC visit 2-years later, the odds of developing frailty tended to be higher among those with mild (OR=1.46; 95%CI=0.91-2.33) and moderate HL (OR=1.43; 95%CI=0.77-2.67). Future research should focus on mechanisms underlying association and determine the impact of treatment of HL. Part of a symposium sponsored by Sensory Health Interest Group.

1398-P: Mortality Implications of Comorbid Health Status in Older Adults with Diabetes: The Atherosclerosis Risk in Communities (ARIC) Study

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1398-P
Author(s):  
MARY R. ROONEY ◽  
OLIVE TANG ◽  
B. GWEN WINDHAM ◽  
JUSTIN B. ECHOUFFO TCHEUGUI ◽  
PAMELA LUTSEY ◽  
...  
Keyword(s):  
Older Adults ◽  
Health Status ◽  
Atherosclerosis Risk In Communities ◽  
Atherosclerosis Risk ◽  
Aric Study

scholarly journals Hemodynamic Correlates of Blood Pressure in Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study

2016 ◽  
Vol 18 (12) ◽  
pp. 1222-1227 ◽  
Author(s):  
Hirofumi Tanaka ◽  
Gerardo Heiss ◽  
Elizabeth L. McCabe ◽  
Michelle L. Meyer ◽  
Amil M. Shah ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Older Adults ◽  
Atherosclerosis Risk In Communities ◽  
Atherosclerosis Risk ◽  
Aric Study

scholarly journals Hearing Screening for Residents in Long-Term Care Homes Who Live with Dementia: A Scoping Review

2021 ◽  
pp. 1-24
Author(s):  
Fiona Höbler ◽  
Katherine S. McGilton ◽  
Walter Wittich ◽  
Kate Dupuis ◽  
Marilyn Reed ◽  
...  
Keyword(s):  
Older Adults ◽  
Hearing Loss ◽  
Nursing Staff ◽  
Scoping Review ◽  
Pure Tone ◽  
Long Term Care ◽  
Pure Tone Audiometry ◽  
Care Homes ◽  
Term Care

Background: Hearing loss is highly prevalent in older adults, particularly among those living with dementia and residing in long-term care homes (LTCHs). Sensory declines can have deleterious effects on functioning and contribute to frailty, but the hearing needs of residents are often unrecognized or unaddressed. Objective: To identify valid and reliable screening measures that are effective for the identification of hearing loss and are suitable for use by nursing staff providing care to residents with dementia in LTCHs. Methods: Electronic databases (Embase, Medline, PsycINFO, CENTRAL, and CINAHL) were searched using comprehensive search strategies, and a stepwise approach based on Arksey & O’Malley’s scoping review and appraisal process was followed. Results: There were 193 scientific papers included in the review. Pure-tone audiometry was the most frequently reported measure to test hearing in older adults living with dementia. However, measures including self- or other-reports and questionnaires, review of medical records, otoscopy, and the whisper test were found to be most suitable for use by nurses working with older adults living with dementia in LTCHs. Conclusion: Although frequently used, the suitability of pure-tone audiometry for use by nursing staff in LTCHs is limited, as standardized audiometry presents challenges for many residents, and specific training is needed to successfully adapt test administration procedures and interpret results. The whisper test was considered to be more suitable for use by staff in LTCH; however, it yields a limited characterization of hearing loss. There remains an urgent need to develop new approaches to screen hearing in LTCHs.

scholarly journals Assessing hearing loss in older adults with a single question and person characteristics; Comparison with pure tone audiometry in the Rotterdam Study

PLoS ONE ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. e0228349 ◽  
Author(s):  
Berthe C. Oosterloo ◽  
Nienke C. Homans ◽  
Rob J. Baatenburg de Jong ◽  
M. Arfan Ikram ◽  
A. Paul Nagtegaal ◽  
...  
Keyword(s):  
Older Adults ◽  
Hearing Loss ◽  
Pure Tone ◽  
Pure Tone Audiometry ◽  
Rotterdam Study ◽  
Person Characteristics ◽  
Single Question

scholarly journals Associations of Cardiac, Kidney, and Diabetes Biomarkers With Peripheral Neuropathy among Older Adults in the Atherosclerosis Risk in Communities (ARIC) Study

2020 ◽  
Vol 66 (5) ◽  
pp. 686-696 ◽  
Author(s):  
Caitlin W Hicks ◽  
Dan Wang ◽  
Natalie R Daya ◽  
B Gwen Windham ◽  
Christie M Ballantyne ◽  
...  
Keyword(s):  
Older Adults ◽  
Peripheral Neuropathy ◽  
Glycated Albumin ◽  
Creatinine Ratio ◽  
Atherosclerosis Risk In Communities ◽  
Hb A1c ◽  
Urine Albumin ◽  
Diabetes Status ◽  
Atherosclerosis Risk ◽  
Aric Study

Abstract Background The aim of this study was to assess the association of high-sensitivity cardiac troponin (hs-cTnT) and other cardiac, kidney, hyperglycemia, and inflammatory biomarkers with peripheral neuropathy (PN) in a community-based population. Methods We conducted a cross-sectional analysis of 3056 black and white participants in the Atherosclerosis Risk in Communities (ARIC) study who underwent standardized monofilament PN testing and had measures of cardiac function (hs-cTnT, N-terminal pro–B-type natriuretic peptide [NT-proBNP], and growth differentiation factor 15 [GDF15]), kidney function (serum creatinine, cystatin C, β-2 microglobulin, urine albumin-to-creatinine ratio), hyperglycemia (fasting glucose, hemoglobin A1c [Hb A1c], fructosamine, glycated albumin, 1,5-anhydroglucitol), and inflammation (C-reactive protein) assessed at visit 6 (2016–2017; age 71–94 years). We used logistic regression to assess the associations of these biomarkers (modeled in diabetes-specific tertiles) with PN in older adults with and without diabetes after adjusting for traditional risk factors. Results In total, 33.5% of participants had PN (37.3% with diabetes and 31.9% without diabetes). There was an independent association of hs-cTnT with PN regardless of diabetes status (diabetes T3 vs. T1: odds ratio [OR], 2.15 [95% CI, 1.44–3.22]; no diabetes: OR, 2.31 [95%CI, 1.76–3.03]; P = 0.72 for interaction). Among participants without diabetes, there were also significant associations of NT-proBNP (OR, 1.40 [95% CI, 1.08–1.81]) and urine albumin-to-creatinine ratio (OR, 1.55 [95% CI, 1.22–1.97]) with PN. Associations of hyperglycemia biomarkers including Hb A1c (OR, 1.76 [95% CI, 1.22–2.54]), fructosamine (OR, 1.71 [95% CI, 1.19–2.46]), and glycated albumin (OR, 1.45 [95% CI, 1.03–2.03]) with PN were significant only among participants with diabetes. Conclusions Overall, hs-cTnT appears to be a global marker of end organ damage, including PN. Laboratory biomarkers may be able to help us identify those individuals with PN.

scholarly journals Hearing Loss, Hearing Aid Use and Depressive Symptoms in Older Adults – Findings from the Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)

2019 ◽  
Author(s):  
Aishwarya Shukla ◽  
Nicholas Reed ◽  
Nicole M Armstrong ◽  
Frank R Lin ◽  
Jennifer A Deal ◽  
...  
Keyword(s):  
Older Adults ◽  
Hearing Loss ◽  
Depressive Symptoms ◽  
Hearing Aid ◽  
Depression Scale ◽  
Normal Hearing ◽  
Community Dwelling ◽  
Atherosclerosis Risk In Communities ◽  
Hearing Aid Use ◽  
Atherosclerosis Risk

Abstract OBJECTIVES Investigate the cross-sectional association between hearing loss (HL), hearing aid use, and depressive symptoms in community-dwelling older adults. METHOD The analytic sample consisted of 3188 participants (age range 71-94 years) in the Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS). Multivariable logistic regression was used to evaluate the association of audiometric hearing status and self-reported hearing aid use with depressive symptoms (11-item Center for Epidemiologic Studies Depression Scale). RESULTS 4.6% of participants had depressive symptoms. 40% had mild HL and 27% had moderate or greater HL. In multivariable-adjusted models, mild HL was associated with 1.90 times higher odds (95% Confidence Interval, [CI] 1.20-3.01) and moderate or greater HL with 2.42 times higher odds (95% CI 1.44-4.07) of depressive symptoms compared to normal hearing. Each 10dB increase in HL was associated with 1.30 higher odds of depressive symptoms (95% CI 1.14-1.49). Hearing aid use was not associated with depressive symptoms among those with mild (Odds Ratio [OR] 0.94, 95% CI 0.35-2.54) or moderate or greater (OR 1.12, 95% CI 0.60-2.11) HL. DISCUSSION Older adults with HL have higher odds of depressive symptoms compared to adults with normal hearing. Future studies are needed to assess whether hearing care is protective against depressive symptoms in older adults.

Abstract P004: Impact of Atrial Fibrillation on Healthcare Utilization in the Community: The Atherosclerosis Risk in Communities (ARIC) Study

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Lindsay G Smith ◽  
Pamela L Lutsey ◽  
Laura R Loehr ◽  
Anna Kucharska-Newton ◽  
Lin Y Chen ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Healthcare Utilization ◽  
Fee For Service ◽  
Atherosclerosis Risk In Communities ◽  
Cardiovascular Comorbidities ◽  
Increased Risk ◽  
Atherosclerosis Risk ◽  
Adjusted Rate ◽  
Aric Study ◽  
The Impact

Background: Atrial fibrillation (AF) is associated with increased risk of hospitalization. However, little is known about the impact of AF on non-inpatient healthcare utilization or about sex or race differences in AF-related utilization. We examined rates of inpatient and outpatient utilization by AF status in the Atherosclerosis Risk in Communities (ARIC) study. Methods and Results: ARIC cohort participants with incident AF enrolled in fee-for-service Medicare, Parts A and B, for at least 12 continuous months between 1991 and 2009 were matched on age, sex, race and center to up to three participants without AF. Healthcare utilization was ascertained from inpatient and outpatient Medicare claims and classified based on primary ICD-9 code. The analysis included 944 AF and 2,761 non-AF participants. The average number of days hospitalized per year was 13.1 (95% confidence interval [CI]: 11.5-15.0) and 2.8 (95% CI: 2.5-3.1) for those with and without AF, respectively. The corresponding number of outpatient claims per year was 53.2 (95% CI: 50.4-56.1) and 23.0 (95% CI: 22.2-23.8) for those with and without AF, respectively (Table). Most utilization in AF patients was attributable to non-AF conditions, particularly other-cardiovascular disease (CVD)-related reasons; the adjusted rate ratio for days hospitalized per year for other-CVD-related reasons was 4.76 (95% CI: 3.51 - 6.44) for those with compared to those without AF. There was suggestive evidence that sex modified the association between AF and inpatient utilization, with AF related to greater utilization in women than men. The association between AF and healthcare utilization was similar in whites and blacks. Conclusions: This study highlights the considerably greater healthcare utilization (inpatient and outpatient) among those with AF; the differential in utilization due to other-CVD-related reasons was substantial. In addition to recommended heart rate or rhythm treatment, accompanying cardiovascular comorbidities should be evaluated and managed.

Abstract P024: Associations Between Carotid-femoral And Estimated Pulse Wave Velocity In Older Adults: The Atherosclerosis Risk In Communities (ARIC) Study

Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Patricia Pagan Lassalle ◽  
Michelle L Meyer ◽  
Kevin S Heffernan ◽  
Adam W Kiefer ◽  
Lauren C Bates ◽  
...  
Keyword(s):  
Older Adults ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Wave ◽  
Atherosclerosis Risk In Communities ◽  
Black And White ◽  
Simple Alternative ◽  
Atherosclerosis Risk ◽  
Screening Device ◽  
Aric Study

Background: Carotid to femoral pulse wave velocity (cfPWV), the gold-standard measure of aortic stiffness, is associated with the incidence of cardiovascular disease (CVD) events. Most cfPWV measurements depend on technical proficiency, which limit broader implementation in clinical settings. Recently, an estimated pulse wave velocity (ePWV) measure derived from age and mean arterial pressure (MAP) has been shown to be associated with the risk of CVD events and all-cause mortality and may be a simple alternative to cfPWV. However, ePWV is poorly predictive in non-White individuals, possibly because it was originally developed from European Cohorts. Consequently, our purpose was to: estimate the strength of association between cfPWV and ePWV, and determine whether agreement is consistent across race. Hypothesis: cfPWV and ePWV are in good agreement and association would be consistent across race. Methods: We included Black and White older adults (n= 4,478; 75.2 [5.0] years) from visit 5 (2011-13) of the community-based Atherosclerosis Risk in Communities Study (ARIC). cfPWV was measured using an automated cardiovascular screening device. ePWV was calculated as presented in Fig 1. Association between cfPWV and ePWV was determined using Pearson’s correlation coefficient (r) and Bland-Altman plots. Results: As reported in Fig 1, there was a weak (r=0.35) correlation between cfPWV and ePWV for the total population, with similar correlations when stratified by Blacks (r=0.31) and Whites (r=0.36). Bland-Altman plots indicated significant systematic differences between cfPWV and ePWV (-0.17 m/s, 95% confidence interval: -0.25 to -0.09 m/s, P <.001), which was consistent by race. Conclusion: In older adults, there was weak correlation between cfPWV and ePWV and systematic differences in agreement. Our results do not support ePWV as a surrogate measure of cfPWV in a sample of older White and Black adults.

scholarly journals Sphingolipids and physical function in the Atherosclerosis Risk in Communities (ARIC) study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Danni Li ◽  
Aniqa B. Alam ◽  
Fang Yu ◽  
Anna Kucharska-Newton ◽  
B. Gwen Windham ◽  
...  
Keyword(s):  
Physical Function ◽  
Walking Speed ◽  
Plasma Concentrations ◽  
P Value ◽  
Cross Sectional ◽  
Atherosclerosis Risk In Communities ◽  
Atherosclerosis Risk ◽  
The Stability ◽  
Aric Study ◽  
Long Chain

AbstractLong-chain sphingomyelins (SMs) may play an important role in the stability of myelin sheath underlying physical function. The objective of this study was to examine the cross-sectional and longitudinal associations of long-chain SMs [SM (41:1), SM (41:2), SM (43:1)] and ceramides [Cer (41:1) and Cer (43:1)] with physical function in the Atherosclerosis Risk in Communities (ARIC) study. Plasma concentrations of SM (41:1), SM (41:2), SM (43:1), Cer (41:1) and Cer (43:1) were measured in 389 ARIC participants in 2011–13. Physical function was assessed by grip strength, Short Physical Performance Battery (SPPB), 4-m walking speed at both 2011–13 and 2016–17, and the modified Rosow-Breslau questionnaire in 2016–2017. Multivariable linear and logistic regression analyses were performed, controlling for demographic and clinical confounders. In cross-sectional analyses, plasma concentrations of SM 41:1 were positively associated with SPPB score (β-coefficients [95% confidence internal]: 0.33 [0.02, 0.63] per 1 standard deviation [SD] increase in log-transformed concentration, p value 0.04), 4-m walking speed (0.042 m/s [0.01, 0.07], p value 0.003), and negatively with self-reported disability (odds ratio = 0.73 [0.65, 0.82], p value < 0.0001). Plasma concentrations of the five metabolites examined were not significantly associated with longitudinal changes in physical function or incidence of poor mobility. In older adults, plasma concentrations of long-chain SM 41:1 were cross-sectionally positively associated with physical function.

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