scholarly journals The Wake Forest IASDR: A Resource for Studying the Effects of Caloric Restriction on Health Outcomes in Older Adults

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 79-79
Author(s):  
Denise Houston ◽  
Jamie Justice ◽  
Anne Newman
Keyword(s):  
Caloric Restriction ◽  
Physical Performance ◽  
Older Americans ◽  
Pooled Data ◽  
The Past ◽  
Aging Studies ◽  
Secondary Analyses ◽  
Using Data ◽  
Baseline Bmi ◽  
Scientific Questions

Abstract Over the past 25+ years, a focus of the Wake Forest Claude D. Pepper Older Americans Independence Center (OAIC) has been to study the consequences of and treatments for geriatric obesity. The Wake Forest OAIC has provided support for 18 clinical trials of caloric restriction (CR), with and without various exercise regimens, in 2,545 adults (71% women, 21% African American) with a mean±SD age of 67.5±5.9 years and BMI ≥27 kg/m2. A priority of the Wake Forest OAIC is to collate and store common data (e.g., demographics, physical performance, cognitive function), biospecimens (blood, muscle, adipose), and images (DXA, CT) from these trials in the Integrated Aging Studies Databank and Repository (IASDR; https://www.peppercenter.org/public/dspIASDR.cfm). This IASDR serves as a resource for the scientific community to foster new scientific questions and analyses. This symposium will provide an overview of CR trials and participants included in the IASDR and how the IASDR supports secondary analyses of CR by highlighting several secondary analyses using data and/or samples from the IASDR. Justice and colleagues examined the effect of CR on a geroscience-guided biomarker index using blood samples from the biorepository. Weaver and colleagues examined the effect of different exercise regimens on CT-derived muscle and bone measures during CR. Miller and colleagues pooled data from 11 trials to determine if CR-induced appendicular lean mass loss is associated with changes in physical performance. Finally, Hsieh and colleagues pooled data from eight trials to examine whether the effect of CR on gait speed differed by baseline BMI and inflammation.

In Debt and Approaching Retirement: Claim Social Security or Work Longer?

2018 ◽  
Vol 108 ◽  
pp. 401-406 ◽  
Author(s):  
Barbara A. Butrica ◽  
Nadia S. Karamcheva
Keyword(s):  
Older Adults ◽  
Social Security ◽  
Labor Force ◽  
Social Security Benefit ◽  
Older Americans ◽  
The Past ◽  
Using Data ◽  
Social Security Benefits ◽  
To Receive ◽  
Retirement Study

Over the past couple of decades, older Americans have become considerably more leveraged. This paper considers whether household debt affects the timing of retirement and Social Security benefit claiming. Using data from the Health and Retirement Study, we find that older adults with debt are more likely to work and less likely to receive Social Security benefits than those who are debt-free. Indebted adults are also more likely to delay fully retiring from the labor force and claiming their benefits. Among the sources of debt, mortgages have a stronger impact on older adults' behavior than do other sources of debt.

scholarly journals Physical Function in U.S. Older Adults Compared With Other Populations: A Multinational Study

2018 ◽  
Vol 31 (7) ◽  
pp. 1067-1084 ◽  
Author(s):  
Dana A. Glei ◽  
Noreen Goldman ◽  
Carol D. Ryff ◽  
Maxine Weinstein
Keyword(s):  
Physical Performance ◽  
Performance Test ◽  
Handgrip Strength ◽  
The United States ◽  
Older Americans ◽  
National Surveys ◽  
Pooled Data ◽  
Local Mean ◽  
Nationally Representative ◽  
Function Peak

Objective: We compare physical performance from three U.S. national surveys and nationally representative surveys in England, Taiwan, and Costa Rica. Method: For each performance test, we use local mean smoothing to plot the age profiles by sex and survey wave and then fit a linear regression model to the pooled data, separately by sex, to test for significant differences across surveys controlling for age and height. Results: Age profiles of performance vary across U.S. surveys, but levels of lung function (peak expiratory flow) and handgrip strength in the United States are as high as they are in the other three countries. Americans also perform as well on the chair stand test as the English and Costa Ricans, if not better, but exhibit slower gait speed than the English at most ages. Discussion: With the exception of walking speed, we find little evidence that older Americans have worse physical performance than their peers.

Increase associated risk of gynaecological cancer due to long-term exposure to high concentration of atmospheric SO2 industrial pollutant

2021 ◽  
pp. 1420326X2110036
Author(s):  
Qian Xu ◽  
Chan Lu ◽  
Rachael Gakii Murithi ◽  
Lanqin Cao
Keyword(s):  
Time Windows ◽  
Air Pollutant ◽  
Gynaecological Cancer ◽  
High Concentration ◽  
The Past ◽  
Short And Long Term ◽  
Using Data ◽  
Air Quality Monitoring Stations ◽  
Control Study

A cohort case–control study was conducted in XiangYa Hospital, Changsha, China, which involved 305 patients and 399 healthy women, from June 2010 to December 2018, to evaluate the association between Chinese women’s short- and long-term exposure to industrial air pollutant, SO2 and gynaecological cancer (GC). We obtained personal and family information from the XiangYa Hospital electronic computer medical records. Using data obtained from the air quality monitoring stations in Changsha, we estimated each woman’s exposure to the industrial air pollutant, sulphur dioxide (SO2), for different time windows, including the past 1, 5, 10 and 15 years before diagnosis of the disease. A multiple logistic regression model was used to assess the association between GC and SO2 exposure. GC was significantly associated with long-term SO2 exposure, with adjusted odds ratio (95% confidence interval) = 1.56 (1.10–2.21) and 1.81 (1.07–3.06) for a per interquartile range increase in the past 10 and 15 years, respectively. Sensitivity analysis showed that different groups reacted in different ways to long-term SO2 exposure. We concluded that long-term exposure to high concentration of industrial pollutant, SO2 is associated with the development of GC. This finding has implications for the prevention and reduction of GC.

Sexual harassment and psychological complaints: student- and class-level associations

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
S Brolin Låftman ◽  
Y Bjereld ◽  
B Modin ◽  
P Löfstedt
Keyword(s):  
School Climate ◽  
Sexual Harassment ◽  
Linear Regression Analysis ◽  
Well Being ◽  
Negative Effects ◽  
School Class ◽  
School Aged Children ◽  
The Past ◽  
Class Level ◽  
Using Data

Abstract Background Students who are subjected to sexual harassment at school report lower psychological well-being than those who are not exposed. Yet, it is possible that the occurrence of sexual harassment in the school class is stressful also for those who are not directly targeted, with potential negative effects on well-being for all students. The aim was to examine whether sexual harassment at the student- and at the class-level was associated with students' psychological complaints. Methods Data from the Swedish Health Behaviour in School-aged Children (HBSC) of 2017/18 was used, with information from students aged 11, 13 and 15 years (n = 3,720 distributed across 209 classes). Psychological complaints were constructed as a summative index of four items capturing how often the student had felt low, felt irritable or bad tempered, felt nervous, or had difficulties to fall asleep, during the past six months (Cronbach's alpha=0.78). Sexual harassment at the student-level was measured by one item concerning bullying at school: “Other students have exposed me to sexual jokes”. Students who reported that this had happened at least “2 or 3 times a month” were classified as exposed to sexual harassment at school. Sexual harassment at the class-level was defined as the school class proportion of students exposed to sexual harassment, reported in per cent. Two-level linear regression analysis was applied. Results Students who had been exposed to sexual harassment had higher levels of psychological complaints (b = 2.74, p < 0.001). The proportion of students in the school class who had been exposed to sexual harassment was also associated with higher levels of psychological complaints, even when adjusting for sexual harassment at the student-level, gender and grade (b = 0.03, p = 0.015). Conclusions Sexual harassment is harmful for those who are exposed, but may also affect other students negatively. Thus, a school climate free from sexual harassment will profit all students. Key messages Using data collected among students aged 11, 13 and 15 years, this study showed that sexual harassment at the student- and class-level was associated with higher levels of psychological complaints. Sexual harassment is harmful for those who are exposed, but may also affect other students negatively. Thus, a school climate free from sexual harassment will profit all students.

Estimation of Construction Waste Generation and Management in Taiwan

2011 ◽  
Vol 243-249 ◽  
pp. 6292-6295 ◽  
Author(s):  
Rong Yau Huang ◽  
Li Hsu Yeh ◽  
Hao Hsien Chen ◽  
Jyh Dong Lin ◽  
Ping Fu Chen ◽  
...  
Keyword(s):  
Decision Tree ◽  
Cross Correlation ◽  
Expert Interviews ◽  
Waste Generation ◽  
Valid Conclusion ◽  
Construction Waste ◽  
Composition Ratio ◽  
The Past ◽  
Highly Correlated ◽  
Using Data

This study examines construction waste generation and management in Taiwan. We verify the factors probable affecting the output of construction wastes by using data for the output of declared construction wastes produced from demolition projects in Taiwan in the last year, expert interviews, and research achievements in the past, and find “ on-site separation” is the factor with effects on the output of construction wastes via cross-correlation by algorithms such as K-Means and Decision Tree C5.0. It can be seen that the output (0.092(t/M3) with on-site separation or 0.329(t/M3) without on-site separation is highly correlated with the composition ratio of construction wastes and referred to as a valid conclusion.

Cannabis Growers in the United States: Findings From a National Household Survey 2010−2014

2021 ◽  
pp. 002204262110004
Author(s):  
Alejandro Azofeifa ◽  
Rosalie L. Pacula ◽  
Margaret E. Mattson
Keyword(s):  
Logistic Regression Model ◽  
Geographical Location ◽  
Household Survey ◽  
The United States ◽  
Multivariable Logistic Regression Model ◽  
Chi Square ◽  
Prevention Education ◽  
The Past ◽  
National Household Survey ◽  
Using Data

Given the rapidly changing U.S. cannabis legislation landscape, the aim of this article is to describe individuals who self-reported growing cannabis in the past year by selected characteristics and geographical location. Using data from 2010 to 2014 National Survey on Drug Use and Health, we conducted bivariate chi-square tests and ran a multivariable logistic regression model to examine the indicators associated with growing cannabis. Approximately, 484,000 individuals aged 12+ self-reported growing cannabis in the past year (1.6% of marijuana users). Predictors of growing cannabis included being male and self-reported reporting using cannabis for a greater number of days. Data showed differences in the proportion of cannabis growers by the state of residence. Obtaining a baseline estimate of cannabis growing practices prior to recreational cannabis markets emerging (2014) is important because such practices may undermine efforts to discourage diversion to youth. Tracking these acquisition patterns will better inform content for public health messaging and prevention education, particularly those targeting youth.

scholarly journals The Economic Impact of Inflammatory Bowel Disease in Canada

2004 ◽  
Vol 18 (4) ◽  
pp. 255-257
Author(s):  
Robert Hilsden
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Labour Force ◽  
Incidence Rates ◽  
Age Group ◽  
Group Level ◽  
The Past ◽  
Inflammatory Bowel ◽  
Using Data ◽  
Very High

Longobardi and colleagues examined the effect of inflammatory bowel disease (IBD) on employment, using data from 10,891 respondents aged 20 to 64 years from the 1998 cycle of the Canadian National Population Health Survey (NPHS) (1). This sample included 187 (1.7%) subjects who self-reported IBD or a similar bowel disorder. A significantly greater proportion of IBD than non-IBD respondents reported that they were not in the labour force (28.9% versus 18.5%). Even after adjusting for other factors (age group, level of pain, etc), subjects with IBD had a 2.9% higher nonparticipation rate (21.4%). For example, among people not hospitalized within the past year and with no limitation of activities due to pain, IBD subjects were 1.2 times more likely to be unemployed than those without IBD. Subjects who reported high levels of pain had a very high probability of being out of the labour force. Based on Canadian annual compensation data for all employed persons in Canada, and age- and sex-specific prevalence, and incidence rates for IBD, the authors estimated that there are 119,980 IBD patients between the ages of 20 and 64 years in Canada and that this group includes 3479 people who are not in the labour force. This translates into lost wages of $104.2 million, or $868 per IBD patient

scholarly journals Orthostatic Blood Pressure Recovery Measured Using a Sphygmomanometer Is Not Associated with Physical Performance or Number of Falls in Geriatric Outpatients

Gerontology ◽  
2021 ◽  
pp. 1-5
Author(s):  
Arjen Mol ◽  
Marieke Esmé Charlotte Blom ◽  
Danique Johanna van den Bosch ◽  
Richard Jack Anton Van Wezel ◽  
Carel G.M. Meskers ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Physical Performance ◽  
Clinical Relevance ◽  
Regression Analyses ◽  
Timed Up And Go ◽  
Entire Cohort ◽  
The Past ◽  
Orthostatic Blood Pressure ◽  
Standing Up ◽  
Age And Sex

<b><i>Background:</i></b> Orthostatic hypotension (OH) and impaired OH recovery derived from beat-to-beat blood pressure (BP) measurements are associated with detrimental clinical outcome, but the clinical relevance of OH recovery assessed using the widely available sphygmomanometer is still unclear. <b><i>Method:</i></b> 635 geriatric outpatients underwent comprehensive geriatric assessment, including orthostatic BP measurements using a sphygmomanometer, during supine rest and 1 and 3 min after standing up and assessment of physical performance (i.e., the timed up and go test and the Short Physical Performance Battery) and the number of falls in the past year. The association between BP recovery, defined as BP at 3 min minus BP at 1 min after standing up, with physical performance and falls was assessed using regression analyses, adjusting for age and sex, both in the entire cohort and after stratifying for the presence of OH at 1 min after standing up. <b><i>Results:</i></b> BP recovery was not associated with physical performance or number of falls, neither in the entire cohort, nor in subpopulations with or without OH. <b><i>Conclusion:</i></b> The clinical relevance of BP recovery between 1 and 3 min after standing up could not be demonstrated. The results suggest that sphygmomanometer measurements have an inadequate time resolution to record the clinically relevant dynamics of orthostatic BP recovery.

African Studies Keyword: Malaria

2021 ◽  
Vol 64 (4) ◽  
pp. 959-985
Author(s):  
Melissa Graboyes ◽  
Zainab Alidina
Keyword(s):  
African Continent ◽  
Historical Knowledge ◽  
Truth Telling ◽  
The Past ◽  
Moral Problems ◽  
History Of ◽  
Global Eradication ◽  
Biomedical Interventions ◽  
Scientific Questions

AbstractFrom nearly any perspective and metric, the effects of malaria on the African continent have been persistent and deep. By focusing on the malady of malaria and the last century of biomedical interventions, Graboyes and Alidina raise critical historical, ethical, and scientific questions related to truth telling, African autonomy, and the obligations of foreign researchers. They provide a condensed history of malaria activities on the continent over the past 120 years, highlighting the overall history of failures to eliminate or control the disease. A case study of the risks of rebound malaria illustrates the practical and moral problems that abound when historical knowledge is ignored. In light of current calls for renewed global eradication efforts, Graboyes and Alidina provide evidence for why historical knowledge must be better integrated into global health epistemic realms.

Programming in Restrictive Housing: Considerations for Improving Outcome Evaluations

2018 ◽  
Vol 45 (8) ◽  
pp. 1174-1191 ◽  
Author(s):  
H. Daniel Butler ◽  
Starr Solomon ◽  
Ryan Spohn
Keyword(s):  
Treatment Effect ◽  
Successful Implementation ◽  
Inmate Misconduct ◽  
The Past ◽  
What Works ◽  
Different Types ◽  
Time Served ◽  
Using Data ◽  
Outcome Evaluations ◽  
Behavioral Programming

A number of studies have identified “what works” in regard to the successful implementation of correctional programming over the past several decades. Few studies, however, have examined the complexities associated with programming in restrictive housing. Using data from a Midwestern department of corrections, we examined whether the provision of programming in restrictive housing achieved desired outcomes (e.g., reductions in inmate misconduct). The findings revealed the amount of time served in restrictive housing and confinement in different types of restrictive housing may influence estimations of a treatment effect. As a growing number of states seek to reform the use of restrictive housing, the proper implementation of cognitive-behavioral programming may increase institutional security and safety.

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