EXAMINING THE TEMPORAL ASSOCIATIONS BETWEEN SUBJECTIVE MEMORY IMPAIRMENT AND DEPRESSIVE SYMPTOMS IN OLDER ADULTS

Background: Subjective memory impairment (SMI) is associated with negative health outcomes including mild cognitive impairment and Alzheimer’s disease. However, ethnic differences in SMI and disparities in risk factors associated with SMI among minority populations are understudied. The study examined the ethnic differences in SMI, whether SMI was associated with depressive symptoms, sleep, and physical activity (PA), and whether the associations vary across racial/ethnic groups. Methods: Participants included 243 African and Asian Americans (including Chinese, Vietnamese, and Korean Americans) aged 50 or older. Demographic information, SMI, depressive symptoms, daily sleeping hours, and PA levels were assessed. Results: Vietnamese Americans reported the highest SMI score. Depressive symptoms, sleeping hours, and PA levels were significantly associated with SMI. Depressive symptoms were the only significant factor across all ethnic groups. Significant interaction effects were found between ethnicity and health behaviors in predicting SMI. In particular, Vietnamese American participants with greater depressive symptoms and physical inactivity were significantly more likely to experience SMI compared to other ethnic groups Conclusions: Our findings demonstrate ethnic differences in SMI and its association with depressive symptoms, sleep, and PA, which highlight the importance of considering the unique cultural and historical backgrounds across different racial/ethnic groups when examining cognitive functioning in elderly.

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TRAJECTORIES OF SUBJECTIVE MEMORY IMPAIRMENT AND OBJECTIVE COGNITIVE DECLINE IN U.S. OLDER ADULTS

Innovation in Aging ◽

10.1093/geroni/igz038.743 ◽

2019 ◽

Vol 3 (Supplement_1) ◽

pp. S205-S205

Author(s):

Hanzhang Xu ◽

Matthew E Dupre ◽

Bei Wu

Keyword(s):

Older Adults ◽

Cognitive Decline ◽

Memory Impairment ◽

Subjective Memory ◽

Subjective Memory Impairment ◽

Logistic Regressions ◽

Dual Trajectories ◽

Nationally Representative ◽

Low Educated ◽

Retirement Study

Abstract We examined the dual trajectories of subjective memory impairment (SMI) and objective cognitive decline and their associated factors in U.S. older adults. We used data from the Health and Retirement Study which includes a nationally representative sample of 19,408 Americans age 65 and older from 1998 to 2016. Trajectories of SMI and objective cognitive decline were simultaneously characterized using a group-based trajectory model and multinomial logistic regressions were used to assess factors associated with the dual-trajectory typologies. Four dual-trajectories were identified: “minimal SMI and stable-low cognitive decline” (33.1% of respondents); “minimal SMI with accelerated cognitive decline” (28.2%); “significant SMI with moderate cognitive decline” (21.0%); and “moderate SMI with steady cognitive decline” (17.6%). Being male, minority, low educated, living alone, and having comorbidities were associated with trajectories featuring greater SMI or more rapid deterioration in cognition. The results suggest complex co-occurring changes in subjective memory and objective cognition in older adults.

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Less depressive symptoms are associated with smaller hippocampus in subjective memory impairment

Archives of Gerontology and Geriatrics ◽

10.1016/j.archger.2013.01.005 ◽

2013 ◽

Vol 57 (1) ◽

pp. 110-115 ◽

Cited By ~ 15

Author(s):

Min-Jeong Kim ◽

Sang Won Seo ◽

Geon Ha Kim ◽

Sung Tae Kim ◽

Jong-Min Lee ◽

...

Keyword(s):

Depressive Symptoms ◽

Memory Impairment ◽

Subjective Memory ◽

Subjective Memory Impairment

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Couple processes of family economic hardship, depressive symptoms, and later-life subjective memory impairment: moderating role of relationship quality

Aging & Mental Health ◽

10.1080/13607863.2020.1758917 ◽

2020 ◽

pp. 1-10

Author(s):

Kandauda A. S. Wickrama ◽

Catherine Walker O’Neal

Keyword(s):

Depressive Symptoms ◽

Relationship Quality ◽

Memory Impairment ◽

Later Life ◽

Economic Hardship ◽

Subjective Memory ◽

Subjective Memory Impairment ◽

Moderating Role

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Subjective memory impairment in older adults: aetiology, salience and help seeking

International Journal of Geriatric Psychiatry ◽

10.1002/gps.2760 ◽

2011 ◽

Vol 27 (6) ◽

pp. 612-620 ◽

Cited By ~ 30

Author(s):

Aysha Begum ◽

Craig Morgan ◽

Chih-Chiang Chiu ◽

Andre Tylee ◽

Robert Stewart

Keyword(s):

Older Adults ◽

Help Seeking ◽

Memory Impairment ◽

Subjective Memory ◽

Subjective Memory Impairment

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Age of major depression onset, depressive symptoms, and risk for subsequent dementia: results of the German Study on Ageing, Cognition, and Dementia in Primary Care Patients (AgeCoDe)

Psychological Medicine ◽

10.1017/s0033291712002449 ◽

2012 ◽

Vol 43 (8) ◽

pp. 1597-1610 ◽

Cited By ~ 44

Author(s):

K. Heser ◽

F. Tebarth ◽

B. Wiese ◽

M. Eisele ◽

H. Bickel ◽

...

Keyword(s):

Depressive Symptoms ◽

Sex Education ◽

Memory Impairment ◽

Late Onset ◽

Subjective Memory ◽

Subjective Memory Impairment ◽

Dementia Risk ◽

Incident Dementia ◽

History Of ◽

The Impact

BackgroundWhether late-onset depression is a risk factor for or a prodrome of dementia remains unclear. We investigated the impact of depressive symptoms and early- v. late-onset depression on subsequent dementia in a cohort of elderly general-practitioner patients (n = 2663, mean age = 81.2 years).MethodRisk for subsequent dementia was estimated over three follow-ups (each 18 months apart) depending on history of depression, particularly age of depression onset, and current depressive symptoms using proportional hazard models. We also examined the additive prediction of incident dementia by depression beyond cognitive impairment.ResultsAn increase of dementia risk for higher age cut-offs of late-onset depression was found. In analyses controlling for age, sex, education, and apolipoprotein E4 genotype, we found that very late-onset depression (aged ⩾70 years) and current depressive symptoms separately predicted all-cause dementia. Combined very late-onset depression with current depressive symptoms was specifically predictive for later Alzheimer's disease (AD; adjusted hazard ratio 5.48, 95% confidence interval 2.41–12.46, p < 0.001). This association was still significant after controlling for cognitive measures, but further analyses suggested that it was mediated by subjective memory impairment with worries.ConclusionsDepression might be a prodrome of AD but not of dementia of other aetiology as very late-onset depression in combination with current depressive symptoms, possibly emerging as a consequence of subjectively perceived worrisome cognitive deterioration, was most predictive. As depression parameters and subjective memory impairment predicted AD independently of objective cognition, clinicians should take this into account.

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