scholarly journals PHYSICAL FUNCTION AND LONGITUDINAL CHANGES IN COGNITIVE FUNCTION

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S815-S815
Author(s):  
Jinjiao Wang ◽  
Jinjiao Wang ◽  
Dexia Kong ◽  
XinQi Dong
Keyword(s):  
Cognitive Function ◽  
Physical Function ◽  
Mini Mental State Examination ◽  
Digit Span ◽  
Chinese Adults ◽  
Older Chinese ◽  
Older Chinese Adults ◽  
The Relationship ◽  
State Examination

Abstract Among 2,038 older Chinese adults in the U.S., we examined the relationship between physical function (Short Performance Physical Battery [SPPB], [instrumental] activities of daily living [ADL/IADL] limitations) at baseline (2011-2013) and changes in cognitive function in the two-year follow-up (2013-2015). Cognitive function was measured by the East Boston Memory Test (EBMT), the Digit Span Backwards assessment (DSB), the Symbol Digit Modalities Test (SDMT), and the Mini-Mental State Examination (MMSE). During the two-year follow-up, 41.8%-50.88% of the participants decreased in cognitive function and 32.88%-44.8% increased. In linear regression that adjusted for baseline cognitive function, education, age, and other covariates, baseline SPPB and ADL/IADL limitations were significantly associated with changes in cognitive function in the two-year follow-up (SPPB: βEBMT=0.0149, p<0.05; βDSB=0.0253, p>0.05; βSDMT=0.2742, p<0.01; βMMSE=0.1070, p<0.001; ADL/IADL limitations: βEBMT= -0.0401, p<0.0001; βDSB= -0.0410, p<0.05; βSDMT= -0.3027, p<0.01; βMMSE= -0.2566, p<0.0001). This suggests that better physical function predicts positive changes in cognitive function.

Living Environment, Built Environment and Cognitive Function among Older Chinese Adults: Results from a Cross-Sectional Study

2021 ◽  
pp. 1-10
Author(s):  
H. Fangfang ◽  
H. Xiao ◽  
Z. Shuai ◽  
W. Qiong ◽  
Z. Jingya ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Function ◽  
Built Environment ◽  
Living Environment ◽  
Chinese Adults ◽  
Cross Sectional ◽  
Older Chinese ◽  
Older Chinese Adults ◽  
The Relationship

Background: Many studies have addressed the relationship between environmental factors and cognitive function; however, evidence from China is very rare. Objectives: To discuss the relationship between the living and built environment and cognitive function among older Chinese adults. Design: The Anhui Healthy Longevity Survey (AHLS) was used to investigate the ability to control major non-communicable diseases through behavioural techniques among adults aged 60 or older dwelling in Anhui Province. A multistage sampling strategy was used to obtain a representative sample. Cross-sectional data were collected for the analyses. Setting: The included participants were recruited from four selected cities in Anhui Province, China. Participants: The participants were adults aged 60 or older and resided in the selected urban or rural communities. Measurements: The Mini Mental State Examination was used to measure the cognitive status of the participants. Mild cognitive impairment (MCI) was defined as illiteracy with MMSE scores lower than 18, MMSE scores lower than 21 among those educated for 0–6 years, or MMSE scores lower than 25 among those with 6 or more years of education. The living environment was assessed by asking the participants about their daily living conditions. The distances between the participants’ dwellings and the nearest facilities and the proportions of green/blue spaces within 800 m buffers were calculated based on the textural address to indicate the built environment. Results: The male participants who lived in a non-dusty environment had higher MMSE scores (β=0.828, 95% CI: 0.240, 1.416, p=0.006) and lower risks of mild cognitive impairment (MCI) (OR=0.651, 95% CI: 0.488, 0.868, p=0.003), and the male participants with no access to recreation spaces had lower MMSE scores (β=-1.107, 95% CI: -1.531, -0.684, p<0.001) and higher risks of MCI (OR=1.403, 95% CI: 1.134, 1.737, p=0.002). The female participants who lived far from a supermarket had significantly lower MMSE scores (Q3:β=-0.750, 95% CI: -1.266, -0.233, p adjusted=0.036; Q4: β=-1.184, 95% CI: -1.745, -0.624, p adjusted<0.001) than those who lived near a supermarket (Q1). Conclusions: The living environment and built environment might have sex-specific associations with cognitive function among older adults.

scholarly journals Exposure to household air pollution and cognitive function in older Chinese adults

2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
T. Tseng ◽  
E. Carter ◽  
L. Yan ◽  
Q. Chan ◽  
L. Zhao ◽  
...  
Keyword(s):  
Air Pollution ◽  
Cognitive Function ◽  
Household Air Pollution ◽  
Chinese Adults ◽  
Older Chinese ◽  
Older Chinese Adults

scholarly journals High density lipoprotein and its apolipoprotein-defined subspecies and risk of dementia

2019 ◽  
Vol 61 (3) ◽  
pp. 445-454 ◽  
Author(s):  
Manja Koch ◽  
Steven T. DeKosky ◽  
Matthew Goodman ◽  
Jiehuan Sun ◽  
Jeremy D. Furtado ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Mini Mental State Examination ◽  
Sandwich Elisa ◽  
Plasma Concentrations ◽  
Density Lipoprotein ◽  
Dementia Risk ◽  
Metabolic Properties ◽  
State Examination ◽  
Baseline Difference

Whether HDL is associated with dementia risk is unclear. In addition to apoA1, other apolipoproteins are found in HDL, creating subspecies of HDL that may have distinct metabolic properties. We measured apoA1, apoC3, and apoJ levels in plasma and apoA1 levels in HDL that contains or lacks apoE, apoJ, or apoC3 using a modified sandwich ELISA in a case-cohort study nested within the Ginkgo Evaluation of Memory Study. We included 995 randomly selected participants and 521 participants who developed dementia during a mean of 5.1 years of follow-up. The level of total apoA1 was not significantly related to dementia risk, regardless of the coexistence of apoC3, apoJ, or apoE. Higher levels of total plasma apoC3 were associated with better cognitive function at baseline (difference in Modified Mini-Mental State Examination scores tertile 3 vs. tertile 1: 0.60; 95% CI: 0.23, 0.98) and a lower dementia risk (adjusted hazard ratio tertile 3 vs. tertile 1: 0.73; 95% CI: 0.55, 0.96). Plasma concentrations of apoA1 in HDL and its apolipoprotein-defined subspecies were not associated with cognitive function at baseline or with the risk of dementia during follow-up. Similar studies in other populations are required to better understand the association between apoC3 and Alzheimer’s disease pathology.

scholarly journals PERCEIVED STRESS, SOCIAL SUPPORT, AND DRY MOUTH AMONG U.S. OLDER CHINESE ADULTS

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S31-S31
Author(s):  
Weiyu Mao ◽  
Weiyu Mao ◽  
Yiwei Chen ◽  
Bei Wu ◽  
Shaoqing Ge ◽  
...  
Keyword(s):  
Social Support ◽  
Oral Health ◽  
Perceived Stress ◽  
Dry Mouth ◽  
Chinese Adults ◽  
Friend Support ◽  
Older Chinese ◽  
Older Chinese Adults ◽  
The Relationship

Abstract Dry mouth is a common condition among older adults that negatively influences oral health, general health, and quality of life. The role of psychosocial factors in oral health conditions and diseases remains largely unknown. We examined the relationship between perceived stress and dry mouth among US older Chinese adults and further investigated the moderating role of social support from different sources in the relationship. Data came from baseline of the Population Study of Chinese Elderly in Chicago between 2011 and 2013 (N = 3,157). Stepwise logistic regression models with interaction terms were used. More perceived stress was significantly associated with a higher likelihood of reporting dry mouth. Friend support was protective against dry mouth. The effect of perceived stress on dry mouth varied by levels of family and friend support. To prevent or reduce dry mouth, interventions need to consider perceived stress and social support in this growing population.

scholarly journals The relationship between olfaction and cognitive function in the elderly

2020 ◽  
Vol 70 (1) ◽  
Author(s):  
Sae Uchida ◽  
Chiho Shimada ◽  
Naoko Sakuma ◽  
Fusako Kagitani ◽  
Akiko Kan ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Mini Mental State Examination ◽  
The Elderly ◽  
Cognitive Measures ◽  
Attentional Function ◽  
Trail Making ◽  
Identification Threshold ◽  
Olfactory Impairment ◽  
The Relationship ◽  
State Examination

Abstract This study investigated the relationship between olfaction and cognitive function in 12 elderly people (age: 80.9 ± 1.6) living in the community. Olfactory function was assessed by the identification threshold for rose odor. Four cognitive measures consisting general cognitive ability assessed by Mini-Mental State Examination (MMSE), its sub-domains, and attentional ability assessed by drawing a line to connect the numbers consecutively (trail-making test part A; TMT-A), were assessed. Subjects with a higher olfactory threshold (≥ 5) declined more in the performance speed of TMT-A (73% ± 7%, p = 0.05) compared with those subjects with a lower threshold (≤ 4) (averaged value was set at 100%). Other cognitive statuses assessed by MMSE tended to decline in subjects with higher thresholds. Because attentional function relates to the basal forebrain cholinergic system, our results suggest that olfactory impairment links to the decline in cognitive function, particularly of attention-relating cholinergic function.

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