scholarly journals ASSOCIATION BETWEEN THE NIH TOOLBOX COGNITION BATTERY AND GAIT IN OLDER ADULTS

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S931-S931
Author(s):  
Kate Hamel ◽  
Sarah Barber ◽  
Carl Ketcham ◽  
Kristy Lui
Keyword(s):  
Older Adults ◽  
Sex Education ◽  
Stride Length ◽  
Dimensional Change ◽  
Community Dwelling ◽  
Trail Making Test ◽  
Card Sort ◽  
Cognitive Predictors ◽  
Trail Making ◽  
Temporal Measures

Abstract The relationship between older adults’ gait and cognition has been well-studied, however there is little consensus regarding a best set of measures to assess cognition. One option that has not been previously examined is the NIH Toolbox Cognition Battery (NIHT-CB), which was developed to be used across the lifespan and across research disciplines. This study examined the relationships between the seven subtests of the NIHT-CB, Trail-Making Tests A and B, and temporospatial measures of gait. One hundred sixty-seven healthy, community-dwelling older adults (115 females, 73.4 ± 4.5 years) completed these cognitive measures and also walked at their self-selected pace back-and-forth five times along a temporospatial-measuring walkway. The mean and coefficient of variation were calculated for each gait variable (stride length, width, time and velocity; stance/swing time and % of stride). After controlling for potential confounders (height, weight, age, sex, education, self-efficacy, health, exercise and falls history), executive function measures were typically the most significant cognitive predictors. More specifically, the Dimensional Change Card Sort task was the best predictor of temporal measures and stride velocity (all ps < 0.001) and the Trail-Making Test Part B was the best predictor for variability measures (five of eight p-values < 0.001). Interestingly, stride length and also stance and swing % of stride were strongly related to a measure of language - Picture Vocabulary (all ps < 0.006). The NIHT-CB appears to be a useful tool for studies of gait in older adults, particularly when used in conjunction with Trail-Making Test B.

scholarly journals 103 Physical Performance among Community-Dwelling Older People in Senawang

2019 ◽  
Vol 48 (Supplement_4) ◽  
pp. iv18-iv27
Author(s):  
Amirah Fatin Ibrahim ◽  
Gaik Kin Teoh ◽  
Mei Chan Chong ◽  
Maw Pin Tan ◽  
Siti Mariam Muda ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Older Adults ◽  
Systolic Blood Pressure ◽  
Community Dwelling ◽  
Trail Making Test ◽  
Left Hand ◽  
Hand Grip ◽  
Trail Making ◽  
The Mean ◽  
Community Dwelling Older Adults

Abstract Introduction Older adults may remove themselves voluntarily from social activities due to health concerns and physical limitations that leads to loneliness. Additionally, loneliness is associated with poorer health among older adults. Therefore, this study aims to improve health status among community-dwelling older adults in the sub-urban area through this social participation project by creating awareness on empowering the older adults in managing their health and social life. Methods This is a community-based participatory research (CBPR) applying both quantitative and qualitative approaches. Quantitative data was obtained with a standardized data collection document and obtained during a series of health screening programs. The data was analyzed using descriptive statistics. Key results 87 older adults participated in two health screening events. The mean age was 66 ± 6.5 (SD) years, median BMI was 26.5 (IQR=6.4), mean systolic blood pressure was 141 ± 14.6 (SD) mmHg, median diastolic blood pressure was 78 (IQR=10) mmHg, median timed up and go was 10 (IQR=3) seconds, median trail-making test A was 45.8 (IQR=24.4) seconds, median trail-making test B was 115.8 (IQR=99.3) seconds. The mean hand grip strength for male was 30.76 ± 5.1 (SD) kg for right hand and 31.87 ± 24.5 (SD) kg for left hand. The mean hand grip strength for female was 18.40 ± 5.1 (SD) kg for right hand and 17.14 ± 5.0 (SD) kg for left hand. Discussion The results may represent a portion of community-dwelling older adults who are actively engage in community activities such as religious classes, weddings or events. Therefore, the results showed normal values for all physical and mental tests. However, 61% of the participants were overweight or obese and had higher mean systolic blood pressure suggesting the need for more education and awareness on health management.

scholarly journals Regression-Based Normative Data for Independent and Cognitively Active Spanish Older Adults: Digit Span, Letters and Numbers, Trail Making Test and Symbol Digit Modalities Test

2021 ◽  
Vol 18 (19) ◽  
pp. 9958
Author(s):  
Clara Iñesta ◽  
Javier Oltra-Cucarella ◽  
Beatriz Bonete-López ◽  
Eva Calderón-Rubio ◽  
Esther Sitges-Maciá
Keyword(s):  
Older Adults ◽  
General Population ◽  
Neuropsychological Assessment ◽  
Normative Data ◽  
Digit Span ◽  
Base Rate ◽  
Community Dwelling ◽  
Trail Making Test ◽  
Active Population ◽  
Trail Making

In this work, we developed normative data for the neuropsychological assessment of independent and cognitively active Spanish older adults over 55 years of age. Method: Regression-based normative data were calculated from a sample of 103 non-depressed independent community-dwelling adults aged 55 or older (67% women). Raw data for Digit Span (DS), Letters and Numbers (LN), the Trail Making Test (TMT), and the Symbol Digit Modalities Test (SDMT) were regressed on age, sex, and education. The model predicting TMT-B scores also included TMT-A scores. Z-scores for the discrepancy between observed and predicted scores were used to identify low scores. The base rate of low scores for SABIEX normative data was compared to the base rate of low scores using published normative data obtained from the general population. Results: The effects of age, sex, and education varied across neuropsychological measures. Although the proportion of low scores was similar between normative datasets, there was no agreement in the identification of cognitively impaired individuals. Conclusions: Normative data obtained from the general population might not be sensitive to identify low scores in cognitively active older adults, incorrectly classifying them as cognitively normal compared to the less-active population. We provide a friendly calculator for use in neuropsychological assessment in cognitively active Spanish people aged 55 or older.

A-11 Investigating Gene–Gene Interactions by Cognitive Domain in Healthy Older Adults

2021 ◽  
Vol 36 (6) ◽  
pp. 1051-1051
Author(s):  
Kendra L Pizzonia ◽  
Andrew M Bryant ◽  
Leatha A Clark ◽  
Brian C Clark ◽  
Julie A Suhr
Keyword(s):  
Executive Functioning ◽  
Cognitive Functioning ◽  
Verbal Fluency ◽  
Community Dwelling ◽  
Gene Interactions ◽  
Trail Making Test ◽  
Semantic Fluency ◽  
Immediate Memory ◽  
Trail Making ◽  
Main Effects

Abstract Objective ApoE is a well-known gene carrying risk for Alzheimer’s disease and is associated with memory performance while the COMT gene is associated with executive functioning but is understudied. The present study investigated these gene interactions across cognitive domains. Method A larger study on gait and aging recruited 89 healthy community-dwelling adults over the age of 60. The primary analyses included 82 participants (67% female, mean age = 74.61, SD = 6.71). The analyses on executive functioning included 72 participants (65% female, mean age = 73.02, SD = 4.99) who completed all measures of interest. ApoE status was defined as presence/absence of Ɛ4. The rs4680 gene on the COMT allele was classified into Val/Met, Val/Val, and Met/Met genotypes. Biological sex was included as a binary term (i.e., male/female). Index variables and age corrected standard scores on the Repeatable Battery for the Assessment of Neuropsychological Status, verbal fluency, and Trail Making Test were included. Results Gene–gene interactions were found for overall cognitive functioning, immediate memory, and semantic fluency. There were main effects of sex for overall cognitive functioning, immediate memory, delayed memory, and semantic fluency. There were main effects for COMT for delayed memory and a main effect for both COMT and ApoE for visuospatial functioning, coding, and verbal fluency (all p’s < 0.05). There were no ApoE x COMT x Sex interactions and Trail Making Test B was not related to either gene or sex. Conclusion(s) Our findings suggest that both COMT and ApoE (and their interaction) influence cognition. Future research should investigate gene–gene interactions in larger samples with more comprehensive cognitive batteries.

scholarly journals Effects of dance on cognitive function in older adults: a systematic review and meta-analysis

2020 ◽  
Author(s):  
Patricia Hewston ◽  
Courtney Clare Kennedy ◽  
Sayem Borhan ◽  
Dafna Merom ◽  
Pasqualina Santaguida ◽  
...  
Keyword(s):  
Older Adults ◽  
Executive Function ◽  
Cognitive Function ◽  
Learning And Memory ◽  
Optimal Dose ◽  
Future Research ◽  
Trail Making Test ◽  
Global Cognitive Function ◽  
Trail Making ◽  
Complex Attention

Abstract Background dance is a mind–body activity that stimulates neuroplasticity. We explored the effect of dance on cognitive function in older adults. Methods we searched MEDLINE, EMBASE, CENTRAL and PsycInfo databases from inception to August 2020 (PROSPERO:CRD42017057138). Inclusion criteria were (i) randomised controlled trials (ii) older adults (aged ≥ 55 years), (iii) intervention—dance and (iv) outcome—cognitive function. Cognitive domains were classified with the Diagnostic and Statistical Manual of Mental Disorders-5 Neurocognitive Framework. Meta-analyses were performed in RevMan5.3 and certainty of evidence with GradePro. Results we reviewed 3,997 records and included 11 studies (N = 1,412 participants). Seven studies included only healthy older adults and four included those with mild cognitive impairment (MCI). Dance interventions varied in frequency (1–3×/week), time (35–60 minutes), duration (3–12 months) and type. We found a mean difference (MD) = 1.58 (95% confidence interval [CI) = 0.21–2.95) on the Mini Mental State Examination for global cognitive function (moderate-certainty evidence), and the Wechsler Memory Test for learning and memory had an MD = 3.02 (95% CI = 1.38–4.65; low-certainty evidence). On the Trail Making Test-A for complex attention, MD = 3.07 (95% CI = −0.81 to 6.95; high-certainty evidence) and on the Trail Making Test-B for executive function, MD = −4.12 (95% CI = −21.28 to 13.03; moderate-certainty evidence). Subgroup analyses did not suggest consistently greater effects in older adults with MCI. Evidence is uncertain for language, and no studies evaluated social cognition or perceptual–motor function. Conclusions dance probably improves global cognitive function and executive function. However, there is little difference in complex attention, and evidence also suggests little effect on learning and memory. Future research is needed to determine the optimal dose and if dance results in greater cognitive benefits than other types of physical activity and exercise.

Predictors of satisfaction with life among older adults

2017 ◽  
Vol 41 (S1) ◽  
pp. S177-S178
Author(s):  
S. Von Humboldt ◽  
I. Leal
Keyword(s):  
Older Adults ◽  
Sex Education ◽  
Adult Children ◽  
Sense Of Coherence ◽  
Structural Equation ◽  
Structural Model ◽  
Satisfaction With Life ◽  
Community Dwelling ◽  
Equation Modeling ◽  
Health Related

IntroductionIncreasing longevity brings challenges for older adults’ satisfaction with life (SWL).AimsThis study aims at exploring a structural model of predictors of SWL in a cross-national sample of older adults.MethodsA community-dwelling sample of 1234 older adults was assessed regarding SWL, sense of coherence (SOC) and socio-demographic, lifestyle and health-related characteristics. Structural equation modeling was used to investigate a structural model of the self-reported SWL, comprising SOC, socio-demographic characteristics (age, sex, education, marital and professional status, household, adult children, income, living setting and religion), lifestyle and health-related characteristics (physical activity, recent disease and medication).ResultsSignificant predictors are SOC (β = .733; P < .001), religion (β = .725; P < .001), income (β = .551; P < .001), adult children (β = .546; P < .001), education (β = –.403; P < .001), living setting (β = –.292; P < .001) and medication (β = –.197; P < .001). The variables accounted for 24.8% of the variability of SWL. Moreover, differences between the four nationality groups (F(3, 671) = 3.671, P = .066) were not found concerning SWL.ConclusionsSense of coherence is the strongest predictor of self-reported SWL. Other predictors are religion, income, adult children, education, living setting and medication. The four nationalities did not present significant differences, concerning SWL. This study highlights the factors that influence older adults’ SWL, namely, SOC, religion and income, as promoters of aging well, within a salutogenic model of health for older populations.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Language dominance and inhibition abilities in bilingual older adults

2013 ◽  
Vol 18 (1) ◽  
pp. 79-89 ◽  
Author(s):  
MIRA GORAL ◽  
LUCA CAMPANELLI ◽  
AVRON SPIRO
Keyword(s):  
Older Adults ◽  
Working Memory ◽  
Language Use ◽  
Simon Task ◽  
Trail Making Test ◽  
Single Test ◽  
Cognitive Domains ◽  
Bilingual Advantage ◽  
Age Related ◽  
Trail Making

This study aimed to examine the so-called bilingual advantage in older adults’ performance in three cognitive domains and to identify whether language use and bilingual type (dominant vs. balanced) predicted performance. The participants were 106 Spanish–English bilinguals ranging in age from 50 years to 84 years. Three cognitive domains were examined (each by a single test): inhibition (the Simon task), alternating attention (the Trail Making test), and working memory (Month Ordering). The data revealed that age was negatively correlated to performance in each domain. Bilingual type – balanced vs. dominant – predicted performance and interacted with age only on the inhibition measure (the Simon task). Balanced bilinguals showed age-related inhibition decline (i.e., greater Simon effect with increasing age); in contrast, dominant bilinguals showed little or no age-related change. The findings suggest that bilingualism may offer cognitive advantage in older age only for a subset of bilinguals.

Clinimetric validity of the Trail Making Test Czech version in Parkinson’s disease and normative data for older adults

2017 ◽  
Vol 31 (sup1) ◽  
pp. 42-60 ◽  
Author(s):  
Ondrej Bezdicek ◽  
Hana Stepankova ◽  
Bradley N. Axelrod ◽  
Tomas Nikolai ◽  
Zdenek Sulc ◽  
...  
Keyword(s):  
Older Adults ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Normative Data ◽  
Trail Making Test ◽  
Trail Making

Transfer Effects of Fall Training on Balance Performance and Spatiotemporal Gait Parameters in Healthy Community-Dwelling Older Adults: A Pilot Study

2014 ◽  
Vol 22 (3) ◽  
pp. 324-333 ◽  
Author(s):  
Lars Donath ◽  
Oliver Faude ◽  
Stephanie A. Bridenbaugh ◽  
Ralf Roth ◽  
Martin Soltermann ◽  
...  
Keyword(s):  
Older Adults ◽  
Dual Task ◽  
Stride Length ◽  
Fear Of Falling ◽  
Community Dwelling ◽  
Stride Time ◽  
Balance Performance ◽  
Transfer Effects ◽  
Gait Parameters ◽  
Community Dwelling Older Adults

This study examined transfer effects of fall training on fear of falling (Falls Efficacy Scale—International [FES–I]), balance performance, and spatiotemporal gait characteristics in older adults. Eighteen community-dwelling older adults (ages 65–85) were randomly assigned to an intervention or control group. The intervention group completed 12 training sessions (60 min, 6 weeks). During pre- and posttesting, we measured FES–I, balance performance (double limb, closed eyes; single limb, open eyes; double limb, open eyes with motor-interfered task), and gait parameters (e.g., velocity; cadence; stride time, stride width, and stride length; variability of stride time and stride length) under single- and motor-interfered tasks. Dual tasks were applied to appraise improvements of cognitive processing during balance and gait. FES–I (p = .33) and postural sway did not significantly change (0.36 < p < .79). Trends toward significant interaction effects were found for step width during normal walking and stride length variability during the motor dual task (p = .05, ηp2 = .22). Fall training did not sufficiently improve fear of falling, balance, or gait performance under single- or dual-task conditions in healthy older adults.

scholarly journals Trail Making contributes to subjective judgment of visual efficiency in older adults

2015 ◽  
Author(s):  
Annalisa Setti ◽  
James Loughman ◽  
George M Savva ◽  
RoseAnne Kenny
Keyword(s):  
Visual Acuity ◽  
Visual Processing ◽  
Community Dwelling ◽  
Functional Health ◽  
Choice Response ◽  
Trail Making Test ◽  
Determinant Factors ◽  
Ocular Pathology ◽  
Self Reports ◽  
Trail Making

Introduction: The determinant factors that influence self-reported quality of vision have yet to be fully elucidated. This study evaluated a range of contextual information, established psychophysical tests, and in particular, a series of cognitive tests as potentially novel determinant factors. Materials & Methods: Community dwelling adults (aged 50+) recruited to Wave 1 of The Irish Longitudinal Study on Ageing, excluding those registered blind, participated in this study (N=5021). Self-reports of vision were analysed in relation to visual acuity and contrast sensitivity, ocular pathology, visual (Choice Response Time task; Trail Making Test) and global cognition. Contextual factors such as having visited an optometrist and wearing glasses were also considered. Ordinal logistic regression was used to determine univariate and multivariate associations. Results and Discussion: Poor Trail Making Test performance (Odds ratio, OR= 1.36), visual acuity (OR =1.72) and ocular pathology (OR=2.25) were determinant factors for poor versus excellent vision in self-reports. Education, wealth, age, depressive symptoms and general cognitive fitness also contributed to determining self-reported vision. Conclusions: Trail Making Test contribution to self-reports may capture higher level visual processing and should be considered when using self-reports to assess vision and its role in cognitive and functional health.

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