scholarly journals Nipah virus infection among abattoir workers in Malaysia, 1998–1999

2001 ◽  
Vol 30 (5) ◽  
pp. 1017-1020 ◽  
Author(s):  
Mazrura Sahani ◽  
Umesh D Parashar ◽  
Roslinah Ali ◽  
Premalatha Das ◽  
MS Lye ◽  
...  
Keyword(s):  
Virus Infection ◽  
Nipah Virus ◽  
Abattoir Workers

Outbreak of Nipah-virus infection among abattoir workers in Singapore

The Lancet ◽  
1999 ◽  
Vol 354 (9186) ◽  
pp. 1253-1256 ◽  
Author(s):  
Nicholas I Paton ◽  
Yee Sin Leo ◽  
Sherif R Zaki ◽  
Alexander P Auchus ◽  
Kim En Lee ◽  
...  
Keyword(s):  
Virus Infection ◽  
Nipah Virus ◽  
Abattoir Workers

scholarly journals Risk Factors for Nipah Virus Infection among Abattoir Workers in Singapore

2000 ◽  
Vol 181 (5) ◽  
pp. 1760-1763 ◽  
Author(s):  
Madeleine H. L. Chew ◽  
Paul M. Arguin ◽  
David K. Shay ◽  
Kee‐Tai Goh ◽  
Pierre E. Rollin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Virus Infection ◽  
Nipah Virus ◽  
Abattoir Workers

Histopathologic and Immunohistochemical Characterization of Nipah Virus Infection in the Guinea Pig

2008 ◽  
Vol 45 (4) ◽  
pp. 576-585 ◽  
Author(s):  
F. J. Torres-Velez ◽  
W.-J. Shieh ◽  
P. E. Rollin ◽  
T. Morken ◽  
C. Brown ◽  
...  
Keyword(s):  
Virus Infection ◽  
Guinea Pig ◽  
Nipah Virus

scholarly journals Chloroquine Administration Does Not Prevent Nipah Virus Infection and Disease in Ferrets

2009 ◽  
Vol 83 (22) ◽  
pp. 11979-11982 ◽  
Author(s):  
Jackie Pallister ◽  
Deborah Middleton ◽  
Gary Crameri ◽  
Manabu Yamada ◽  
Reuben Klein ◽  
...  
Keyword(s):  
Virus Infection ◽  
Nipah Virus ◽  
Disease Outbreaks ◽  
Mortality Rates ◽  
Hendra Virus ◽  
Malaria Therapy ◽  
Sporadic Disease

ABSTRACT Hendra virus and Nipah virus, two zoonotic paramyxoviruses in the genus Henipavirus, have recently emerged and continue to cause sporadic disease outbreaks in humans and animals. Mortality rates of up to 75% have been reported in humans, but there are presently no clinically licensed therapeutics for treating henipavirus-induced disease. A recent report indicated that chloroquine, used in malaria therapy for over 70 years, prevented infection with Nipah virus in vitro. Chloroquine was assessed using a ferret model of lethal Nipah virus infection and found to be ineffective against Nipah virus infection in vivo.

scholarly journals A survey of Nipah virus infection among various risk groups in Singapore

2002 ◽  
Vol 128 (1) ◽  
pp. 93-98 ◽  
Author(s):  
K. P. CHAN ◽  
P. E. ROLLIN ◽  
T. G. KSIAZEK ◽  
Y. S. LEO ◽  
K. T. GOH ◽  
...  
Keyword(s):  
Neutralizing Antibodies ◽  
Healthcare Workers ◽  
Past History ◽  
Nipah Virus ◽  
Risk Groups ◽  
Asymptomatic Infection ◽  
Infected People ◽  
The People ◽  
History Of ◽  
Abattoir Workers

Following the Nipah virus (NV) outbreak in March 1999 in Singapore, a serological survey was undertaken to screen individuals potentially exposed to NV. Blood samples were tested for NV IgM, IgG and neutralizing antibodies. Twenty-two (1·5%) of 1469 people tested had antibodies suggesting NV infection. Although 12 of the 22 infected people (54·6%) were symptomatic, the remaining 10 (45·4%) were clinically well and had no past history of compatible pulmonary or neurological disease. Clinical and serological findings suggested three people had been infected with NV before the outbreak was recognized. All those who were infected were male abattoir workers. None of the people who had contact with horses, and no healthcare workers exposed to infected patients and their specimens had detectable antibodies. This study provides evidence that NV causes asymptomatic infection. All of the antibody positive individuals had direct contact with pigs and there was no evidence of human to human transmission.

scholarly journals A Mathematical Model for Nipah Virus Infection

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Assefa Denekew Zewdie ◽  
Sunita Gakkhar
Keyword(s):  
Virus Infection ◽  
Reproduction Number ◽  
Initial Conditions ◽  
Nipah Virus ◽  
Virus Transmission ◽  
Globally Asymptotically Stable ◽  
Dead Bodies ◽  
Manifold Theory ◽  
The Impact ◽  
The Given

It has been reported that unprotected contact with the dead bodies of infected individuals is a plausible way of Nipah virus transmission. An SIRD model is proposed in this paper to investigate the impact of unprotected contact with dead bodies of infected individuals before burial or cremation and their disposal rate on the dynamics of Nipah virus infection. The model is analyzed, and the reproduction number is computed. It is established that the disease-free state is globally asymptotically stable when the reproduction number is less than unity and unstable if it is greater than unity. By using the central manifold theory, we observe that the endemic equilibrium is locally stable near to unity. It is concluded that minimizing unsafe contact with the infected dead body and/or burial or cremation as fast as possible contributes positively. Further, the numerical simulations for the given choice of data and initial conditions illustrate that the endemic state is stable and the disease persists in the community when the reproduction number is greater than one.

scholarly journals Nipah virus infection: current scenario

2013 ◽  
Vol 24 (3) ◽  
pp. 398-408 ◽  
Author(s):  
D. D. Kulkarni ◽  
C. Tosh ◽  
G. Venkatesh ◽  
D. Senthil Kumar
Keyword(s):  
Virus Infection ◽  
Nipah Virus ◽  
Current Scenario
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