Game dynamic model of social distancing while cost of infection varies with epidemic burden

2018 ◽  
Vol 84 (1) ◽  
pp. 23-43 ◽  
Author(s):  
Samit Bhattacharyya ◽  
Timothy Reluga
Author(s):  
Miguel Casares ◽  
Hashmat Khan

The continued spread of COVID-19 suggests a significant possibility of reimposing the lockdowns and stricter social distancing similar to the early phase of pandemic control. We present a dynamic model to quantify the impact of isolation for the contagion curves. The model is calibrated to the COVID-19 outbreak in Spain to study the effects of the isolation enforcement following the declaration of the state of alarm (14 March 2020). The simulations indicate that both the timing and the intensity of the isolation enforcement are crucial for the COVID-19 spread. For example, a 4-day earlier intervention for social distancing would have reduced the number of COVID-19 infected people by 67%. The model also informs us that the isolation enforcement does not delay the peak day of the epidemic but slows down its end. When relaxing social distancing, a reduction of the contagion probability (with the generalization of preventive actions, such as face mask wearing and hands sanitizing) is needed to overcome the effect of a rise in the number of interpersonal encounters. We report a threshold level for the contagion pace to avoid a second COVID-19 outbreak in Spain.


2012 ◽  
Vol 295 ◽  
pp. 194-203 ◽  
Author(s):  
Eunha Shim ◽  
John J. Grefenstette ◽  
Steven M. Albert ◽  
Brigid E. Cakouros ◽  
Donald S. Burke
Keyword(s):  

2012 ◽  
Vol 74 (7) ◽  
pp. 1469-1484 ◽  
Author(s):  
Yuanyuan Huang ◽  
Zhijun Wu
Keyword(s):  

2021 ◽  
Vol 8 ◽  
Author(s):  
Sachit Butail ◽  
Maurizio Porfiri

In an emergency evacuation, people almost always come in close proximity as they quickly leave a built environment under a potential threat. With COVID19, this situation presents yet another challenge: that of getting unintentionally exposed to an infected individual. To assess the epidemiological consequences of an emergency evacuation, we expanded a popular pedestrian dynamic model to enable social distancing during a normal exit and analyze the effect of possible transmission through respiratory droplets and aerosol. Computer simulations point to a troubling outcome, whereby the benefits of a quick exit could be outweighed by the risk of infection.


2008 ◽  
Vol 45 ◽  
pp. 147-160 ◽  
Author(s):  
Jörg Schaber ◽  
Edda Klipp

Volume is a highly regulated property of cells, because it critically affects intracellular concentration. In the present chapter, we focus on the short-term volume regulation in yeast as a consequence of a shift in extracellular osmotic conditions. We review a basic thermodynamic framework to model volume and solute flows. In addition, we try to select a model for turgor, which is an important hydrodynamic property, especially in walled cells. Finally, we demonstrate the validity of the presented approach by fitting the dynamic model to a time course of volume change upon osmotic shock in yeast.


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