When do general practitioners request urine specimens for microbiology analysis? The applicability of antibiotic resistance surveillance based on routinely collected data

Aim: The objectives of the study were measuring knowledge, attitude, and practice scores among general practitioners on antibiotic resistance; exploring associations between antibiotics prescribing practice score among general practitioners and their knowledge and attitude scores after adjusting for other factors; and identifying barriers for rational antibiotics prescription by general practitioners. Methods: A cross-sectional study design was used. A self-administered survey was conducted among general practitioners employed in private and public polyclinics in Yerevan, Armenia. All general practitioners, working in Yerevan polyclinics and fluent in the Armenian language, were eligible for the study. The study was conducted in primary healthcare facilities of Yerevan, Armenia. All polyclinics (n=18) serving 30,000 or more populations were included in the study. All general practitioners available in selected polyclinics at the time of the survey were invited to take part in the survey, to target 20 general practitioners from each polyclinic. Results: Overall, 291 general practitioners participated in the study. Knowledge, attitude, and practice mean percent scores were 58.3%, 67.5%, and 63.0%, respectively. In the adjusted analysis, the practice percent score was significantly associated with the attitude percent score, though the relationship between the practice and knowledge scores was insignificant. The main barriers reported by general practitioners: lack of rapid diagnostic tests, high costs of laboratory tests, high costs of some antibiotics, and lack of guidelines. Conclusion: Identified low knowledge, attitude, and practice mean percent scores suggest a need for improvements in these areas. Availability of rapid and inexpensive diagnostic tests, enforcement of prescriptions could potentially prevent the development of antibiotic resistance. Keywords: drug resistance, general practitioners, polyclinics, prescribing

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ANTIBACTERIAL SURVEILLANCE: AN APPROACH TO MITIGATING MULTI-DRUG RESISTANCE MENACE AMONG CLINICAL UROPATHOGENS IN EKITI STATE, NIGERIA

Bacterial Empire ◽

10.36547/be.2020.3.2.10-13 ◽

2020 ◽

Vol 3 (2) ◽

pp. 10

Author(s):

Seye Julius Oladeji ◽

Gbenga Victor Kayejo

Keyword(s):

Antibiotic Resistance ◽

Tertiary Care ◽

Multi Drug Resistance ◽

Care Hospital ◽

Gram Negative ◽

Microbiological Methods ◽

Resistance Patterns ◽

Etiological Agents ◽

Tract Infections ◽

Urine Specimens

Urinary tract infections (UTIs) are among the most common human infections with the distribution of etiological agents and antibiotic resistance patterns varying from region to region and from time to time. The aims of this study were to ascertain the prevalence and antibiotic resistance profiles of common Gram-negative uropathogens among patients attending a Tertiary Care Hospital in Ekiti State, Nigeria. One hundred and fifty clean-catch midstream urine specimens were obtained and cultured within 2 hours of collection for the detection of Gram-negative uropathogens. The isolated organisms were identified by standard microbiological methods. Of the total 150 urine specimens analyzed, 82 (54.67%) specimens were positive for Gram-negative uropathogen with significant bacteriuria of which 34 (41.46%) were males and 48 (58.54%) were females. Klebsiella spp. 38 (46.34%) and Escherichia coli 32 (39.02%) were the most frequently isolated Gram-negative uropathogens, followed by Proteus mirabilis 10 (12.20%) while the least occurring uropathogen was observed to be Pseudomonas aeruginosa 2 (2.44%). All the isolated uropathogens were observed to be highly resistant to the commonly prescribed antibiotics. Emerging resistance to carbapenems was also observed. Nevertheless, carbapenems showed highest susceptibility compared to other tested antibiotics. Conclusively, high levels of resistance of uropathogens to antibiotics exist in our setting. This therefore calls for continuous antibiotic surveillance and improved antibiotic stewardship.

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General practitioners’ knowledge, attitudes and practices on antibiotic prescribing for acute respiratory infections in children in Lubumbashi, Democratic Republic of Congo

Journal of Pulmonology and Respiratory Research ◽

10.29328/journal.jprr.1001015 ◽

2020 ◽

Vol 4 (1) ◽

pp. 011-017

Author(s):

Wembonyama Kasongo Aubin Ndjadi ◽

Mukuku Olivier ◽

Kanteng Gray A-Wakamb ◽

Shongo Mick Ya-Pongombo ◽

Mutombo André Kabamba ◽

...

Keyword(s):

Antibiotic Resistance ◽

General Practitioners ◽

Democratic Republic ◽

Democratic Republic Of Congo ◽

Antibiotic Prescribing ◽

Motivation To Change ◽

Cross Sectional Survey ◽

Republic Of Congo ◽

Attitudes And Practices ◽

Knowledge Attitudes And Practices

Objective: To assess the knowledge, attitudes and practices declared among general practitioners (GPs) concerning the use of antibiotics for the treatment of ARI in children under 5 years in Lubumbashi. Methods: A cross-sectional survey was conducted to assess the level of knowledge, attitude and practices concerning antibiotic prescribing among 67 GPs working in the pediatric setting in various health structures in Lubumbashi city, in the Democratic Republic of Congo. Data were collected from April 1st to June 30th, 2020. Results: GPs had limited knowledge about antibiotic prescriptions (mean of 46% correct answers to 8 questions). Although they are generally concerned about antibiotic resistance (mean ± SD = 0.50 ± 0.68), and are unwilling to submit to pressure to prescribe antibiotics to meet patient demands and expectations (mean ± SD = –1.78 ± 0.31) and the requirements to prescribe antibiotics for fear of losing patients (mean ± SD = –1.67 ± 0.47), there was a lack of motivation to change prescribing practices (mean ± SD = −0.37 ± 0.94) and strong agreement that they themselves should take responsibility for tackling antibiotic resistance (mean ± SD = 1.24 ± 0.74). Multiple linear regression results showed that higher knowledge scores were associated with less avoidance of responsibility when prescribing antibiotics (β = 0.919; p = 0.000). Conclusion: To curb the over-prescription of antibiotics, it is not enough to improve knowledge in itself. The lack of motivation of physicians to change must be addressed through a systematic approach. These data show the need for interventions that support the rational prescribing of antibiotics.

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S42.3: Prevalence and determinants of antibiotic resistance of faecal Enterococci among unselected patients attending general practitioners in Southern Germany

Biometrical Journal ◽

10.1002/bimj.200490147 ◽

2004 ◽

Vol 46 (S1) ◽

pp. 92-92

Author(s):

Susanne Lietzau ◽

Elke Raum ◽

Marina Hoewner ◽

Heike von Baum ◽

Rheinhard Marre ◽

...

Keyword(s):

Antibiotic Resistance ◽

General Practitioners ◽

Southern Germany

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Prevalence and determinants of antibiotic resistance in faecalEscherichia coli among unselected patients attending general practitioners in Southwest Germany

Pharmacoepidemiology and Drug Safety ◽

10.1002/pds.861 ◽

2004 ◽

Vol 13 (5) ◽

pp. 303-308 ◽

Cited By ~ 6

Author(s):

Til Stürmer ◽

Andrea Erb ◽

Reinhard Marre ◽

Hermann Brenner

Keyword(s):

Antibiotic Resistance ◽

General Practitioners ◽

Southwest Germany

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Effect of antibiotic therapy on the antibiotic resistance of faecal Escherichia coli in patients attending general practitioners

Journal of Antimicrobial Chemotherapy ◽

10.1093/jac/34.2.239 ◽

1994 ◽

Vol 34 (2) ◽

pp. 239-246 ◽

Cited By ~ 12

Author(s):

N. London ◽

R. Nijsten ◽

P. Mertens ◽

A. v. d. Bogaard ◽

E. Stobberingh

Keyword(s):

Escherichia Coli ◽

Antibiotic Resistance ◽

Antibiotic Therapy ◽

General Practitioners

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Knowledge, attitude and practice towards antibiotic resistance among general practitioners in Armenia

European Journal of Public Health ◽

10.1093/eurpub/ckab165.461 ◽

2021 ◽

Vol 31 (Supplement_3) ◽

Author(s):

D Muradyan ◽

A Demirchyan ◽

V Petrosyan

Keyword(s):

Antibiotic Resistance ◽

General Practitioners ◽

Diagnostic Tests ◽

Public Health Issue ◽

Prescribing Practices ◽

Cross Sectional ◽

Attitude And Practice ◽

Prescribing Practice ◽

Knowledge And Attitude ◽

Knowledge Attitude And Practice

Abstract Background Antibiotic resistance is an important public health issue. This study sought to measure general practitioners' (GPs) knowledge, attitude, and practice on antibiotic resistance; explore the adjusted associations between their antibiotics prescribing practice score and knowledge and attitude scores, and identify barriers for rational prescription of antibiotics by GPs. Methods A cross-sectional self-administered survey was conducted among GPs. Multivariable linear regression was applied to analyze the data. Results Overall, 291 GPs participated in the study. Knowledge, attitude, and practice mean percent scores were 58.3%, 67.5%, and 63.0%, respectively. In the adjusted analysis, the practice percent score was significantly associated with the attitude percent score (β = 0.58; 95% CI: 0.41, 0.75; p < 0.001), though the relation between the practice and knowledge scores was insignificant. The main barriers reported by GPs: lack of rapid diagnostic tests, high costs of laboratory tests, high costs of some antibiotics, and lack of guidelines. Conclusions Identified low knowledge, attitude, and practice mean percent scores suggest a need for improvements in these areas. Availability of rapid and inexpensive diagnostic tests, enforcement of prescriptions could potentially prevent the development of antibiotic resistance. Key messages Availability of rapid and inexpensive diagnostic tests, enforcement of prescriptions, and regulation of antibiotics’ prices could help to improve antibiotics prescribing practices of GPs. Low knowledge, attitude and practice levels regarding antibiotic resistance among GPs in polyclinics suggests a need for improvement in these areas.

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