Rheumatoid Arthritis Patient Presenting for a Total Knee Replacement

2018 ◽  
pp. 237-239
Author(s):  
Perin Kothari ◽  
Sree Kolli
Keyword(s):  
Rheumatoid Arthritis ◽  
Cervical Spine ◽  
Rheumatoid Arthritis Patient ◽  
Connective Tissue ◽  
Preoperative Assessment ◽  
Connective Tissue Disorder ◽  
Multiple Organ ◽  
Organ Systems ◽  
Intraoperative Management ◽  
Total Knee

Rheumatoid arthritis (RA) is a progressive connective tissue disorder. Patients with RA have several concerns relevant to the anesthesiologist. RA can affect multiple organ systems beyond simply the joints. A thorough history and physical is needed to evaluate for cardiac, respiratory, and neurologic abnormalities. Furthermore, cervical spine involvement is very common for patients with RA. Special consideration is needed for airway management of these patients. In addition, radiographic imaging may be helpful in evaluating the extent of the disease. Regional and neuraxial anesthesia may be alternatives to general anesthesia in patients with RA when possible. This chapter discusses preoperative assessment and intraoperative management of patients with RA.

scholarly journals A Case Report of Marfan Syndrome with Literature Review

2015 ◽  
Vol 4 (4) ◽  
pp. 269
Author(s):  
Hemanth Kumar Kalla ◽  
Swarna Kumari ◽  
CH Rama rao ◽  
MKR Parthasarathy ◽  
S Surya prakash Reddy ◽  
...  
Keyword(s):  
Case Report ◽  
Connective Tissue ◽  
Marfan Syndrome ◽  
Clinical Signs ◽  
Connective Tissue Disorder ◽  
Multiple Organ ◽  
Review Of The Literature ◽  
Organ Systems ◽  
Loin Pain ◽  
Routine Physical Examination

Marfan syndrome(MFS) is a connective tissue disorder that affects multiple organ systems. Cardiovascular, ocular, and skeletal abnormalities are cardinal features of the syndrome. Its incidence is among the highest of any heritable disorder.Most patients who have Marfan syndrome are usually diagnosed incidentally when they present for a routine physical examination for various reasons. The purpose of this paper is to provide a review of the literature, as well as describe a 22-year-old male with MFS and right hydroureteronephrosis diagnosed incidentally when he attended our hospital for complaints of fever and right loin pain. This case report emphasizes importance of “Revised Ghent criteria” for the diagnosis of MFS and highlights various clinical signs of MFS<strong>.</strong>

A Case Report of Marfan Syndrome with Literature Review

2015 ◽  
Vol 4 (4) ◽  
pp. 269
Author(s):  
Hemanth Kumar Kalla ◽  
Swarna Kumari ◽  
CH Rama rao ◽  
MKR Parthasarathy ◽  
S Surya prakash Reddy ◽  
...  
Keyword(s):  
Case Report ◽  
Connective Tissue ◽  
Marfan Syndrome ◽  
Clinical Signs ◽  
Connective Tissue Disorder ◽  
Multiple Organ ◽  
Review Of The Literature ◽  
Organ Systems ◽  
Loin Pain ◽  
Routine Physical Examination

Marfan syndrome(MFS) is a connective tissue disorder that affects multiple organ systems. Cardiovascular, ocular, and skeletal abnormalities are cardinal features of the syndrome. Its incidence is among the highest of any heritable disorder.Most patients who have Marfan syndrome are usually diagnosed incidentally when they present for a routine physical examination for various reasons. The purpose of this paper is to provide a review of the literature, as well as describe a 22-year-old male with MFS and right hydroureteronephrosis diagnosed incidentally when he attended our hospital for complaints of fever and right loin pain. This case report emphasizes importance of “Revised Ghent criteria” for the diagnosis of MFS and highlights various clinical signs of MFS<strong>.</strong>

MARFAN SYNDROME AND PREGNANCY: CLINICAL IMPLICATIONS AND MANAGEMENT

2010 ◽  
Vol 21 (3) ◽  
pp. 225-241
Author(s):  
ARIADNA C GRIGORIU ◽  
JACK COLMAN ◽  
CANDICE K SILVERSIDES ◽  
RACHEL WALD ◽  
SAMUEL C SIU ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Marfan Syndrome ◽  
Autosomal Dominant ◽  
De Novo ◽  
Connective Tissue Disorder ◽  
Multiple Organ ◽  
Clinical Implications ◽  
Organ Systems

Marfan syndrome (MFS) is an autosomal dominant connective tissue disorder that affects multiple organ systems, primarily the cardiovascular, ocular and skeletal. It is the most common inherited condition affecting the heart and the aorta, occurring in 1:5000–1:9800 people. There is no ethnic or gender predisposition; 20 to 35% of cases arise fromde novomutations.

scholarly journals Atypical presentation of rheumatoid arthritis: a case of massive bilateral pleural effusions in a patient with Caplan syndrome

2019 ◽  
Vol 12 (10) ◽  
pp. e231899
Author(s):  
Yinglun Wu ◽  
Philip C Dittmar
Keyword(s):  
Rheumatoid Arthritis ◽  
Atrial Fibrillation ◽  
Pleural Effusion ◽  
Connective Tissue ◽  
Minimal Change Disease ◽  
Connective Tissue Disorder ◽  
Minimal Change ◽  
Atypical Presentation ◽  
Pleural Effusions ◽  
Recent Treatment

Rheumatoid arthritis (RA) is a common connective tissue disorder affecting the synovial joints. In patients with RA, involvement of the lungs occurs in 30%–40% of cases while pleural effusions occur in only 3%–5%. However, the majority of RA-associated pleural effusions are small, unilateral and asymptomatic. We present a case of massive bilateral pleural effusions in a patient with established rheumatoid pneumoconiosis (Caplan syndrome). Interestingly, the pleural effusion occurred following recent treatment for minimal change disease and atrial fibrillation.

Proteus syndrome with huge tonsillar mass causing dysphagia: a rare case

2006 ◽  
Vol 120 (5) ◽  
pp. 408-410 ◽  
Author(s):  
J K Sahni ◽  
S Kumar ◽  
V Wadhwa ◽  
G Kathuria
Keyword(s):  
Connective Tissue ◽  
Rare Case ◽  
Vascular Malformations ◽  
Multiple Organ ◽  
Proteus Syndrome ◽  
Orthopaedic Surgeons ◽  
Organ Systems

Proteus syndrome is a rare and highly variable hamartomatous syndrome that can affect multiple organ systems. It is characterized by hyperplasia of connective tissue, vascular malformations, epidermal naevi and hyperostosis. Most of the cases present to plastic and orthopaedic surgeons. Otolaryngologic presentations are minimal. We report such a rare case, which presented with a huge unilateral tonsillar mass causing dysphagia.

scholarly journals Clinical Utility of Preoperative Assessment in Ovarian Cancer Cytoreduction

Diagnostics ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 568
Author(s):  
Pratistha Koirala ◽  
Ashley S Moon ◽  
Linus Chuang
Keyword(s):  
Ovarian Cancer ◽  
Clinical Utility ◽  
Gynecologic Cancer ◽  
Preoperative Assessment ◽  
Late Presentation ◽  
Multiple Organ ◽  
Optimal Management ◽  
Novel Therapies ◽  
Organ Systems ◽  
Disseminated Disease

Ovarian cancer is the deadliest gynecologic cancer, in part due to late presentation. Many women have vague early symptoms and present with disseminated disease. Cytoreductive surgery can be extensive, involving multiple organ systems. Novel therapies and recent clinical trials have provided evidence that, compared to primary cytoreduction, neoadjuvant chemotherapy has equivalent survival outcomes with less morbidity. There is increasing need for validated tools and mechanisms for clinicians to determine the optimal management of ovarian cancer patients.

scholarly journals Surgical Treatment of the Cervical Spine in the Rheumatoid Arthritis Patient.

1995 ◽  
Vol 44 (2) ◽  
pp. 794-797
Author(s):  
Haruhisa Yanagida ◽  
Tatsuoki Mashima ◽  
Masakazu Kondoh ◽  
Norio Shinohara ◽  
Koichiro Yokoyama ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Cervical Spine ◽  
Rheumatoid Arthritis Patient ◽  
Surgical Treatment

scholarly journals Genotypic Categorization of Loeys-Dietz Syndrome Based on 24 Novel Families and Literature Data

Genes ◽  
2019 ◽  
Vol 10 (10) ◽  
pp. 764 ◽  
Author(s):  
Camerota ◽  
Ritelli ◽  
Wischmeijer ◽  
Majore ◽  
Cinquina ◽  
...  
Keyword(s):  
Cervical Spine ◽  
Connective Tissue ◽  
Spontaneous Pneumothorax ◽  
Age Of Onset ◽  
Phenotypic Variability ◽  
Connective Tissue Disorder ◽  
Cervical Spine Instability ◽  
Cutaneous Manifestations ◽  
Life Threatening ◽  
Arterial Aneurysms

Loeys-Dietz syndrome (LDS) is a connective tissue disorder first described in 2005 featuring aortic/arterial aneurysms, dissections, and tortuosity associated with craniofacial, osteoarticular, musculoskeletal, and cutaneous manifestations. Heterozygous mutations in 6 genes (TGFBR1/2, TGFB2/3, SMAD2/3), encoding components of the TGF-β pathway, cause LDS. Such genetic heterogeneity mirrors broad phenotypic variability with significant differences, especially in terms of the age of onset, penetrance, and severity of life-threatening vascular manifestations and multiorgan involvement, indicating the need to obtain genotype-to-phenotype correlations for personalized management and counseling. Herein, we report on a cohort of 34 LDS patients from 24 families all receiving a molecular diagnosis. Fifteen variants were novel, affecting the TGFBR1 (6), TGFBR2 (6), SMAD3 (2), and TGFB2 (1) genes. Clinical features were scored for each distinct gene and matched with literature data to strengthen genotype-phenotype correlations such as more severe vascular manifestations in TGFBR1/2-related LDS. Additional features included spontaneous pneumothorax in SMAD3-related LDS and cervical spine instability in TGFB2-related LDS. Our study broadens the clinical and molecular spectrum of LDS and indicates that a phenotypic continuum emerges as more patients are described, although genotype-phenotype correlations may still contribute to clinical management.

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