Patterns of Inheritance in Neurogenetic Disease
Keyword(s):
The human genome consists of approximately 22,000 genes that are encoded within the nuclear DNA and embedded in the chromosome. Mitochondria are the only cytoplasmic organelles that have their own DNA. Nuclear gene disorders and mitochondrial inheritance are discussed in this chapter. Nuclear gene disorders follow the patterns of inheritance originally described by Gregor Mendel. They often are referred to as single-gene disorders because 1 or more alleles of only 1 locus are the major determinants of phenotype.
2007 ◽
Vol 2007
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pp. 183-184
Synaptic Plasticity as a Therapeutic Target in the Treatment of Autism-related Single-gene Disorders
2013 ◽
Vol 19
(36)
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pp. 6480-6490
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Keyword(s):
Keyword(s):
2006 ◽
Vol 8
(10)
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pp. 1-26
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Keyword(s):
Keyword(s):