Global burden of diabetes and depression

Author(s):  
Julio Licinio ◽  
Andreas L. Birkenfeld ◽  
Stefan R. Bornstein

Diabetes and depression are two of the major global health concerns in the twenty-first century. One way of measuring the global impact of these illnesses are the disability-adjusted life-years or DALYs. The calculation takes into account the average life expectancy of a specific country, the years lost by premature death, and the years lived with disability/disease. Furthermore, ongoing research has shown that interactions exist between depression and diabetes. Diabetes and other chronic diseases can lead to depression, while depression can increase the risk for developing diabetes or worsen the course of diabetes. In this book, the current understanding of the interactions between depression and diabetes will be discussed, highlighting various pathways in which these morbidities are linked. In addition, the authors give outlooks on how diabetes and depression might be treated in the future.

Author(s):  
João Costa ◽  
Joana Alarcão ◽  
Francisco Araujo ◽  
Raquel Ascenção ◽  
Daniel Caldeira ◽  
...  

Abstract Aims This article sought to estimate the burden of disease attributable to atherosclerosis in mainland Portugal in 2016. Methods and results The burden of atherosclerosis was measured in disability-adjusted life years following the latest 2010 Global Burden of Disease (GBD) methodology. Disability-adjusted life years were estimated as the sum of years of life lost (YLL) with years lived with disability (YLD). The following clinical manifestations of atherosclerosis were included: ischaemic heart disease (IHD) (including acute myocardial infarction, stable angina, and ischaemic heart failure), ischaemic cerebrovascular disease (ICVD), and peripheral arterial disease (PAD). Years of life lost were estimated based on all-cause mortality data for the Portuguese population and mortality due to IHD, ICVD, and PAD for the year 2016 sourced from national statistics. Standard life expectancy was sourced from the GBD study. Years lived with disability corresponded to the product of the number of prevalent cases by an average disability weight for all possible combinations of disease. Prevalence data for the different clinical manifestations of atherosclerosis were sourced from epidemiological studies. Disability weights were sourced from the published literature. In 2016, 15 123 deaths were attributable to atherosclerosis, which corresponded to 14.3% of overall mortality in mainland Portugal. Disability-adjusted life years totalled 260 943, 75% due to premature death (196 438 YLL) and 25% due to disability (64 505 YLD). Conclusion Atherosclerosis entails a high disease burden to society. A large part of this burden would be avoidable if evidence-based effective and cost-effective interventions targeting known risk factors, from prevention to treatment, were implemented.


Cardiovascular diseases (CVDs) are a major cause of premature death worldwide and a cause of loss of disability-adjusted life years. For most types of CVD early diagnosis and intervention are independent drivers of patient outcome. Clinicians must be properly trained and centres appropriately equipped in order to deal with these critically ill cardiac patients. This new updated edition of the textbook continues to comprehensively approach all the different issues relating to intensive and acute cardiovascular care and addresses all those involved in intensive and acute cardiac care, not only cardiologists but also critical care specialists, emergency physicians and healthcare professionals. The chapters cover the various acute cardiovascular diseases that need high quality intensive treatment as well as organisational issues, cooperation among professionals, and interaction with other specialities in medicine.


Author(s):  
Fateme Parandin ◽  
Fatemeh Heydarpour ◽  
Mehdi Mohebali ◽  
Ahmad Ali Hanafi-Bojd ◽  
Ali Akbari Sari ◽  
...  

Background: Human hydatidosis as a public concern has increased in a number of countries that have reduced control programs for the disease due to lack of resources or policies. We aimed to estimate Disability-Adjusted Life Years (DALYs) for human hydatidosis in Iran in 2018. Methods: Data were collected from the Center of Communicable Diseases Control, Ministry of Health &Medical Education, Tehran, Iran in 2018. To calculate DALYs, years of life lost due to premature death (YLL) with years of life with disability (YLD) were calculated according to the formula as DALY = YLL + YLD. The standard life expectancy lost method (SEYLL) was used to calculate the years lost due to premature death. Results: DALYs for human hydatidosis was calculated as 1210.12 years (YLD equals to 177.12 and YLL equals to 1033) in Iran for the year 2018. It was estimated to be 700.2 years for men and 509.8 years for women.  DALYs in men were significantly different from women (P= 0.001) so DALYs were more in men than women were. YLD was calculated at 78.228 years in men and 98.892 years in women and in both men and women at 177.12 years. YLD was significantly different in women compared to men (P=0.001), so YLD in women was more than in men. Conclusion: We reached considerable indices for hydatidosis in our study. Therefore, disease prevention and control programs in Iran seem necessary by the policy makers.


Viruses ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 184
Author(s):  
John P Harris ◽  
Miren Iturriza-Gomara ◽  
Sarah J O’Brien

Disability adjusted life years (DALYs) have been used since the 1990s. It is a composite measure of years of life lost with years lived with disability. Essentially, one DALY is the equivalent of a year of healthy life lost if a person had not experienced disease. Norovirus is the most common cause of gastrointestinal diseases worldwide. Norovirus activity varies from one season to the next for reasons not fully explained. Infection with norovirus is generally not severe, and is normally characterized as mild and self-limiting with no long-term sequelae. In this study, we model a range of estimates of DALYs for community cases of norovirus in England and Wales. We estimated a range of DALYs for norovirus to account for mixing of the severity of disease and the range of length of illness experienced by infected people. Our estimates were between 1159 and 4283 DALYs per year, or 0.3–1.2 years of healthy life lost per thousand cases of norovirus. These estimates provide evidence that norovirus leads to a considerable level of ill health in England and Wales. This information will be helpful should candidate norovirus vaccines become available in the future.


2020 ◽  
Author(s):  
Win Ei Ei Thaw ◽  
Wantanee Phanprasit ◽  
Kwanjai Amnatsatsue ◽  
Ariya Bunnagamchairat ◽  
Kanitta Bundhamcharoen

ABSTRACTBackgroundRoad traffic injury (RTI) is growing public health problem in Myanmar. In addition, every count in road crush is followed by remarkable burdens in the community. In this study, burden of disease (BOD) approach is used to quantify this hidden problem in the studied area.Aim/Objective/PurposeTo assess the burden of traffic injuries in Nay Pyi Taw Union Territory, MyanmarMethodsThis cross-sectional study analyzed 16,338 traffic injury victims in injury registry, from 2012 to 2016. The burden was estimated by disability-adjusted life years (DALYs). The analysis was disaggregated by sex, age and type of road users, as well as expressed the rate by per 100,000 population.Results/OutcomesIt was 60,962 DALYs in total for the studied period, with the rate of 1050.85 per 100,000 population. Although premature death in road crash was only 6.2% in the study, it attributed 87.8% of total burden. Total DALYs contributed by male were three-times higher than female. Nearly half of burden came from the young and productive population of 15-29 years. The highest DALYs rate was seen in the 20-24 years in male and 30-34 years in female. The highest RTI burden was due to motorized two-wheelers, with 69.4% of total DALYs.ConclusionThis study initiates usefulness of local data from injury registry to calculate the burden of injury. The findings highlight a huge burden of traffic injuries in the community, focusing on the hidden contribution of fatal cases and the vulnerability of young adult, male and motorcyclists in traffic accidents.


Author(s):  
Eric Bonnefoy-Cudraz ◽  
Susanna Price ◽  
Marco Tubaro ◽  
Pascal Vranckx ◽  
Christiaan Vrints

Cardiovascular diseases (CVDs) are a major cause of premature death worldwide and an important cause of loss of disability-adjusted life years. For most types of CVD early diagnosis (within minutes) and intervention are independent drivers of patient outcome. Clinicians must be properly trained and centres appropriately equipped in order to deal with these critically ill cardiac patients.


2015 ◽  
Vol 49 (0) ◽  
Author(s):  
Luísa Sorio Flor ◽  
Monica Rodrigues Campos ◽  
Andreia Ferreira de Oliveira ◽  
Joyce Mendes de Andrade Schramm

OBJECTIVE To estimate the burden of type 2 diabetes mellitus and its percentage attributable to overweight and obesity in Brazil.METHODS The burden of diabetes mellitus was described in terms of disability-adjusted life years, which is the sum of two components: years of life lost and years lived with disability. To calculate the fraction of diabetes mellitus attributable to overweight, obesity, and excess weight, we used the prevalence of these risk factors according to sex and age groups (> 20 years) obtained from the 2008 Pesquisa Dimensões Sociais das Desigualdades (Social Dimensions of Inequality Survey) and the relative risks derived from the international literature.RESULTS Diabetes mellitus accounted for 5.4% of Brazilian disability-adjusted life years in 2008, with the largest fraction attributed to the morbidity component (years lived with disability). Women exhibited higher values for disability-adjusted life years. In Brazil, 49.2%, 58.3%, and 70.6% of diabetes mellitus in women was attributable to overweight, obesity, and excess weight, respectively. Among men, these percentages were 40.5%, 45.4%, and 60.3%, respectively. Differences were observed with respect to Brazilian regions and age groups.CONCLUSIONS A large fraction of diabetes mellitus was attributable to preventable individual risk factors and, in about six years, the contribution of these factors significant increased, particularly among men. Policies aimed at promoting healthy lifestyle habits, such as a balanced diet and physical activity, can have a significant impact on reducing the burden of diabetes mellitus in Brazil.


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