Preparation for renal replacement therapy

Author(s):  
Muh Geot Wong ◽  
Bruce A. Cooper ◽  
Carol A. Pollock

Although the primary aim of management in chronic kidney disease (CKD) is to prevent progression to stage 5 CKD, for many patients renal replacement therapy (RRT) is inevitable. Planning for the initiation of dialysis is aimed at ensuring that it takes place in a supported environment in which adverse events will be minimized, that the modality chosen is appropriate for the individual circumstances, and the patient has full knowledge of what RRT entails. Beginning dialysis inevitably involves medical, psychological, family, and social issues, and preparation for RRT is optimally managed by a team with appropriate expertise in these areas. Multidisciplinary education programmes that inform patients and their families about their disease and the treatment options are likely to result in patients starting dialysis in a planned and elective manner.

2019 ◽  
Vol 9 (2) ◽  
pp. 125-134
Author(s):  
Leszek Gromadziński ◽  
Beata Januszko-Giergielewicz ◽  
Kamila Czarnacka ◽  
Piotr Pruszczyk

Background: The risk of cardiovascular (CV) complications is much greater in patients with chronic kidney disease (CKD). The aim of this study was to assess predictors of mortality, renal failure progression, and the need for dialysis in patients with CKD. Methods: The study group consisted of 70 patients with stage 3–5 CKD, followed up on average for 33.4 ± 15.6 months. Laboratory tests and echocardiography were performed on all patients. Composite endpoints were defined as (1) all-cause mortality and (2) mortality or renal replacement therapy (RRT), defined as the initiation of dialysis therapy. Results: During the observation period, 13 patients died and 11 began dialysis therapy. NT-proBNP was found to be a significant predictor in receiver operating characteristic curve analysis for all study endpoints. The optimal cutoff value for NT-proBNP as a predictor of mortality was 569.8 pg/mL, with a sensitivity of 53.8% and a specificity of 89.1%. For mortality or RRT, the cutoff value for NT-proBNP was 384.9 pg/mL, with a sensitivity and specificity of 70.8 and 72.7%, respectively. In a multivariate regression analysis, NT-proBNP was an independent predictor of mortality with an OR = 7.5 (95% CI: 1.05–53.87; p = 0.044) and of mortality or RRT with an OR = 4.7 (95% CI: 1.01–22.66; p = 0.048). Conclusions: NT-proBNP is an independent predictor of mortality in patients with CKD and can also be useful for CV risk stratification in this patient population.


Nefrología ◽  
2021 ◽  
Author(s):  
Luis Alberto Dorantes-Carrillo ◽  
Martha Medina-Escobedo ◽  
Yaseth Aridai Cobá-Canto ◽  
Alberto Alvarez-Baeza ◽  
Nina Méndez Domínguez

PLoS ONE ◽  
2020 ◽  
Vol 15 (6) ◽  
pp. e0233976 ◽  
Author(s):  
Erik Dovgan ◽  
Anton Gradišek ◽  
Mitja Luštrek ◽  
Mohy Uddin ◽  
Aldilas Achmad Nursetyo ◽  
...  

2013 ◽  
Vol 1 (2) ◽  
pp. 72-74 ◽  
Author(s):  
Joerg Latus ◽  
Elisabeth Höring ◽  
Matthias Voehringer ◽  
Dieter Ratge ◽  
M. Dominik Alscher ◽  
...  

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii390-iii391
Author(s):  
Yavuz Yenicierioglu ◽  
Hakan Akdam ◽  
Belda Dursin ◽  
Alper Alp ◽  
Funda Saglam Iyiler ◽  
...  

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