scholarly journals P1502IS AGE JUST A NUMBER? - HEMODIALYSIS IN OCTOGENARIAN PATIENTS IN A PORTUGUESE CENTRAL HOSPITAL

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Daniela Alferes ◽  
Marinha Silva ◽  
Joana Couto ◽  
Ana Ventura ◽  
Clemente Sousa ◽  
...  

Abstract Background and Aims The option of a non-dialytic or conservative approach to elderly patients with End-Stage Renal Disease (ESRD) as an alternative to dialysis has a great interest in clinical practice. Among elderly patients with ESRD, the octogenarian ones raise the most difficult decisions with respect to indication and dialysis therapy management, furthermore the evidence about the clinical outcomes is lacking in this group of patient. The main objectives of this study were the analysis the comorbidities and clinical condition of pre-ESRD octogenarians who initiated dialysis and the estimation of the effect of such treatment on this patient group’s comorbid status. Method The authors performed a retrospective and statistical analysis on patients with aged ≥ 80 years who initiated hemodialysis treatment in a Portuguese Central Hospital between 2007 and 2017. A total of 88 patients were included in the study. Results The mean age of the group was 84±2.8 years; 61.4% were men. Nearly all the patients (97.7%) had one or more comorbid conditions of which the most common were hypertension (86.4%), heart disease (58%) and diabetes (43.2%). In 60.2% of the patients the functional activity was normal (Karnofsky score ≥80). Hemodialysis was initiated in an emergency situation in 58% of the patients and the majority (59.1%) had an arteriovenous fistula as vascular access. In the 2 years previous to dialysis therapy, most patients (54.5%) had at least one hospitalization (min=1; max=4). During the two years of follow-up, the number of hospital admissions decreased (p=0.034) and only 39.8% of the patients required hospital admission (min=1; max=3) (table 1), with shorter average hospital stay (p=0.013) (table 2). The main causes of hospitalization in the pre-dialysis period were renal related-diseases, in contrast the admissions were due to non-access related infections and vascular access complications after dialysis had initiated. Most patients died (67%) at the end of follow-up mainly due to non-vascular access infections or sepsis (32.2%). The significant causes of death found by Cox regression were chronic kidney disease secondary to systemic disease, Karnofsky score and hospital stay in the 2-year-dialysis period (table 3). Conclusion Advanced age in itself should not be used as an excluding factor of dialysis treatment. Comorbidity and performance status are the factors that should exert the greatest influence on such decision. In this sample, the majority of patients had few comorbidities, a good functional activity and they initiated dialysis by an autologous vascular access which may have contributed to the good outcomeS. This study found a decrease in the number of hospitalizations in the dialysis period which can be explained by regular clinical monitoring in every dialysis treatment, preventing or even treating intercurrent illnesses and avoiding hospital admissions.

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Vinant Bhargava ◽  
Priti Meena ◽  
Ambrish Satwik ◽  
Apurv Srivastava ◽  
A K Bhalla ◽  
...  

Abstract Background and Aims With the increase in the line expectancy of chronic kidney disease in the older population (>60 years), the numbers requiring haemodialysis is progressively rising. The elderly population may be different from the younger in terms of non-suitable vessels for access creation, non-maturation, and vascular calcifications, and this may alter the outcomes of use of arteriovenous fistula (AVF). This study was conducted to analyse the outcomes of AVF in elderly patients (>60 years). Method Retrospective study was conducted in the Department of Nephrology at Sir Ganga Ram Hospital, New Delhi. Patients of more than 60 years of age in whom AVF was created from 1st January 2012 to 31st December 2016 were included in the study. Follow-up data of 3.5 years was analysed. The primary endpoint was to assess primary and secondary patency rates. Results A total of 300 patients were included in the study. The mean age was 63.8 years. Radiocephalic AVF (RCAVF) was the most common site of [69.8% (n = 210)], followed by brachiocephalic (BCAVF) in 25.2% (n = 75) and basilic vein transposition (BVT) in 5% (n = 15). At 12 months, overall survival of the AVF was 66.8%. At 42 months, the primary patency rate of RCAVF, BCAVF, and BVT was 50.6%, 52.6%, and 50.4% respectively. The commonest cause of access failure was thrombosis (20.4%) followed by non-maturation (9%). Vascular access abandonment was found least in BCAVF. Conclusion AVF remains the preferred vascular access for haemodialysis in the elderly population. Brachiocephalic AVF has higher primary and secondary patency rates. Thrombosis and failure of maturation are major concerns in the elderly AVF.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Maurice A. Lembeck ◽  
Lau C. Thygesen ◽  
Birgitte Dreyer Sørensen ◽  
Lisbeth Lumby Rasmussen ◽  
Ellen A. Holm

Abstract Background Unplanned hospital admissions are costly and prevention of these has been a focus for research for decades. With this study we aimed to determine whether discharge planning including a single follow-up home visit reduces readmission rate. The intervention is not representing a new method but contributes to the evidence concerning intensity of the intervention in this patient group. Methods This study was a centrally randomized single-center controlled trial comparing intervention to usual care with investigator-blinded outcome assessment. Patients above the age of 65 were discharged from a single Danish hospital during 2013–2014 serving a rural and low socioeconomic area. For intervention patients study and department nurses reviewed discharge planning the day before discharge. On the day of discharge, study nurses accompanied the patient to their home, where they met with the municipal nurse. Together with the patient they reviewed cognitive skills, medicine, nutrition, mobility, functional status, and future appointments in the health care sector and intervened if appropriate. Readmission at any hospital in Denmark within 8, 30, and 180 days after discharge is reported. Secondary outcomes were time to first readmission, number of readmissions, length of stay, and readmission with Ambulatory Care Sensitive Conditions, visits to general practitioners, municipal services, and mortality. Results One thousand forty-nine patients aged > 65 years discharged from medical, geriatric, emergency, surgical or orthopedic departments met inclusion criteria characteristic of frailty, e.g. low functional status, need of more personal help and multiple medications. Among 945 eligible patients, 544 were randomized. Seven patients died before discharge. 56% in the intervention group and 54% in the control group were readmitted (p = 0.71) and 23% from the intervention group and 22% from the control group died within 180 days. There were no significant differences between intervention and control groups concerning other secondary outcomes. Conclusions There was no effect of a single follow-up home visit on readmission in a group of frail elderly patients discharged from hospital. Trial registration https://clinicaltrials.gov (identifier NCT02318680), retrospectively registered December 11, 2014.


2021 ◽  
Vol 7 (1) ◽  
pp. e13-e13
Author(s):  
Santiago Silva ◽  
Cristina Milano ◽  
Gonzalo García ◽  
Anabel Abib ◽  
Carlos Díaz ◽  
...  

Introduction: Frailty (F) refers to the cumulative organic damage caused by aging, as a consequence of a diminished physiological reserve. Frailty’s prevalence is 73% in dialysis. Objectives: Our aim was to identify the prevalence of F in patients starting hemodialysis (HD) or hemodiafiltration online (HDF) treatment. To asses change in frailty during a six-month period of dialysis Patients and Methods: This prospective cohort study evaluated 67 incident patient starting-HD or HDF at one year, with a follow-up period of at least six months. The frailty was assessed by the Fried frailty method. According to this test, we divided the population in two groups: Pre-frail (0-2) and frail (3-5). Results: Mean age was 64 years, 64% were male and 92% were treated with HD. A total of 35.8% of the patients were admitted to dialysis with a prosthetic or native fistula. The prevalence of F at the beginning of dialysis was 65.7%. The mean value of Charlson index (CHI) was 5.2 ± 2. There was a significant correlation between CHI and frailty test (P<0.0001). Basal F score (n=67) improved after 6 month (n=52): 3 (2-4) versus1 (1-2) (P<0.0001). Hematocrit (28 versus 32% P=0.05) and calcium levels (8.6 and 8.9 mg/dL, P<0.002) also increased after sixth-month. Global mortality was 7.5%. In the multivariate analysis CHI (P<0.001) and albumin (P=0.003) were frailty predictors. Conclusion: The prevalence of F in patients who start dialysis therapy is high. There was an improvement in F score after six-month of dialysis treatment. Patients with higher F score had higher mortality with higher CHI


2013 ◽  
Vol 40 (5) ◽  
pp. 374-379 ◽  
Author(s):  
Devajit Chowlek Shyam ◽  
Amy Grace Rapsang

OBJECTIVE: to evaluate a one year experience with inguinal hernia repair, in patients of > 50years, with respect to the type of inguinal hernia, type of surgery, postoperative complications and recurrence. METHODS: a prospective descriptive study of patients (n=57) > 50 years operated for inguinal hernia during a one year period. Tension-free meshplasty and herniorrhaphy, using 3"x6" polypropylene mesh and 2-0 polypropylene suture, were performed in elective and emergency surgery respectively. Follow-up visits were scheduled at six weeks, three and six months postoperatively. RESULTS: the most representative age group was 61-70 years, and all patients were male. 52 (91.22%) patients had unilateral inguinal hernias, while five (8.77%) had bilateral hernias. In 50 (87.71%) patients, the hernia was uncomplicated, while seven (12.28%) patients presented with some complication such as obstruction or strangulation. Elective surgery was performed in 50 (87.71%) patients while seven (12.28%) patients were operated in emergency. Postoperatively, 50 (87.7%) patients had uneventful recovery, while seven (12.28%) patients developed some complications which were treated conservatively. Mean hospital stay was six days. One recurrence was observed and there was no peri/postoperative death. CONCLUSION: tension-free meshplasty and herniorrhaphy are safe, simple and applicable even in elderly patients after adequate pre-operative assessment and optimization. Although associated with longer hospital stay, the mortality rate is nil and complication as well as recurrence rate is low. Hence, timely repair is necessary in elderly patients even in those with comorbid conditions.


2013 ◽  
Vol 10 (2) ◽  
pp. 116-122 ◽  
Author(s):  
Tushar J. Vachharajani ◽  
Louise M. Moist ◽  
Marc H. Glickman ◽  
Miguel A. Vazquez ◽  
Kevan R. Polkinghorne ◽  
...  

2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S634-S634
Author(s):  
M M Diaz Alcazar ◽  
P Martinez Tirado ◽  
B Vidal Vilchez ◽  
B Zuñiga de Mora Figueroa

Abstract Background The characteristics of inflammatory Bowel Disease (IBD) seem different according to the age of the patient at diagnosis. Moreover, age influences the evolution of the disease. The aim of the study was to know the prevalence of IBD in patients older than 65 years old and the evolution of the disease at this age. Methods Retrospective descriptive study. Database from patients of the Hospital Universitario San Cecilio of Granada (Spain). 50 patients with 65 years old or more and 50 under this age have been randomly selected. Their electronic clinical records have been reviewed. Results The IBD Unit in our Hospital serves 1218 people with this disease, of whom 212 are elderly patients (17.4%). In the serie of 100 randomly selected patients, mean age is 58.42 years. The disease began before 65 years old in 74% of elderly patients. All the elderly patients continue follow-up, while 4 (8%) of the younger patients dropped out the follow-up in the IBD Unit. With regard to hospital admissions, 27 elderly patients (54%) have never required hospitalisation compared with 18 (36%) aged under 65 years. Corticosteroids were used at diagnosis in 27 (54%) of older vs. 28 (56%) of the younger patients. Meanwhile, topical treatment is used by 33 (66%) of older vs. 22 (44%) of the younger ones. The current treatment is summarised in Figure 1. Conclusion (1) The prevalence of IBD is increasing. IBD in older patients is also escalating due to the low mortality of the disease and the increase of patients with late-onset. In our serie, the prevalence in elderly patients is 17.4%. (2) UC is more frequent in older patients than in younger ones (70% vs. 42%). With regard to CD, penetrating disease is less frequent in older patients but stricturing pattern is more prevalent. (3) Adherence to follow-up in elderly patients is higher and they need fewer hospital admissions than younger patients. (4) In our serie, surgical and biological treatments are less frequent in elderly patients. Moreover, there are more patients above 65 years that do not take maintenance treatment or they only take mesalamine. (5) Chronological age is different from biological age. Older patients with a good quality of life should not be excluded from new treatments or clinical trials due to age. More evidence about older patients is needed to improve de diagnosis, the knowledge about the evolution and define better the treatment in this group of age.


Swiss Surgery ◽  
2002 ◽  
Vol 8 (6) ◽  
pp. 255-258 ◽  
Author(s):  
Perruchoud ◽  
Vuilleumier ◽  
Givel

Aims: The purpose of this study was to evaluate excision and open granulation versus excision and primary closure as treatments for pilonidal sinus. Subjects and methods: We evaluated a group of 141 patients operated on for a pilonidal sinus between 1991 and 1995. Ninety patients were treated by excision and open granulation, 34 patients by excision and primary closure and 17 patients by incision and drainage, as a unique treatment of an infected pilonidal sinus. Results: The first group, receiving treatment of excision and open granulation, experienced the following outcomes: average length of hospital stay, four days; average healing time; 72 days; average number of post-operative ambulatory visits, 40; average off-work delay, 38 days; and average follow-up time, 43 months. There were five recurrences (6%) in this group during the follow-up period. For the second group treated by excision and primary closure, the corresponding outcome measurements were as follows: average length of hospital stay, four days; average healing time, 23 days; primary healing failure rate, 9%; average number of post-operative ambulatory visits, 6; average off-work delay, 21 days. The average follow-up time was 34 months, and two recurrences (6%) were observed during the follow-up period. In the third group, seventeen patients benefited from an incision and drainage as unique treatment. The mean follow-up was 37 months. Five recurrences (29%) were noticed, requiring a new operation in all the cases. Discussion and conclusion: This series of 141 patients is too limited to permit final conclusions to be drawn concerning significant advantages of one form of treatment compared to the other. Nevertheless, primary closure offers the advantages of quicker healing time, fewer post-operative visits and shorter time off work. When a primary closure can be carried out, it should be routinely considered for socio-economical and comfort reasons.


Author(s):  
Dhawal Panchal ◽  
Firdaus Dekhaiya ◽  
Harin Tailor

In today’s mechanized world, Blunt Abdominal Trauma (BAT) is a common emergency which is associated with considerable morbidity and mortality. More than 75% of abdominal traumas are blunt in nature and liver and spleen are the commonest organs to be injured as a result of BAT. The aim is to analyse and compare two groups of patient of blunt abdominal trauma managed conservatively with drainage and one by exploratory laparotomy. 50 cases of blunt abdominal trauma were taken. The patient were studied  which includes age ,sex, mode of injury, initial vitals on presentation, Mortality in each group, duration of hospital stay, pre interventions and post interventions state and requirements, complications and follow up. It was observed 48% of patients were in between age group ranging from 10 to 30. Overall in terms of sex ratio, males dominated the no. of cases. RTA was most common mode of trauma. Liver and spleen was most common organ to be injured. Patients managed by laparotomy had higher mortality rate, duration of hospital stay was more, and complication were more. Early diagnosis and repeated clinical examination and use of appropriate investigation form the key in managing blunt injury abdomen patients. Keywords:  Blunt Abdominal Trauma, Haemoperitoneum , laparotomy , Abdominal Drainage.


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