Economic Evaluation of New Drugs
As a result of new cost-containment incentives found in both public and private healthcare plans, providers and insurers are subjecting new healthcare services, and especially pharmaceuticals, to evaluations in which costs and benefits are explicitly compared. Collectively, this body of work is referred to as health technology assessment. This chapter discusses in detail the three methodologies most frequently utilized in HTA: cost-benefit analysis, cost-effectiveness analysis, and cost-utility analysis. The appropriate roles for each of these approaches and examples of their applications in several influential HTA organizations around the world are elaborated, including the National Institute for Health and Care Excellence in the UK, the Pharmaceutical Benefits Advisory Committee in Australia, and the Canadian Agency for Drugs and Technologies in Health. The history and current state of HTA in the United States is also examined in the chapter.