The development of evolutionary theory over the course of the 19th century was not confined to the theory of evolution by natural selection posited by Charles Darwin (b. 1809–d. 1882) and Alfred Russell Wallace (b. 1823–d. 1913). Encompassing the burgeoning science of geology, natural history, and biology and eventually being adapted into sociology, psychology, political theory, economics, and cultural anthropology, the theory of evolution quickly became both pervasive and divisive. Prior to Darwin’s intervention with the Origin of Species (1859), various theories of evolution were circulating, being accommodated within the field of natural theology or constituting a challenge to theories of intelligent design. Over the period, the interplay between literature and evolutionary theory was complex and pronounced: advances in science provoked new formal and thematic concerns for writers, and scientists used poetry and literary techniques to disseminate their arguments to wide readerships. During the period, the rise of natural historical study as a popular pursuit, and the Victorian emphasis on nature study as a moral, even religious, pursuit, meant that evolutionary ideas were adapted for various purposes and contested in both popular and specialist texts. Pre-Darwinian literature circulated evolutionary ideas mainly within the framework of natural theology (proving and discussing God’s existence through the study of Creation), but visions of harmony and beneficent design were challenged through the theory of natural selection, meaning that post-Darwinian literature more fully encompasses anthropological anxiety and the falling off of faith. Religious texts, and theological concerns, are thus central to the interplay between literature and science in the period. Toward the end of the century, the adaptation of Darwinism and evolutionary theory into various disciplines saw a proliferation of social Darwinism, branching off into eugenics, the impact of which would be felt most fully in the 20th century. This article focuses on writing and evolutionary theory in its immediate British and 19th-century contexts.