scholarly journals 33 NeoCHIRP: A Collaborative Care Model for Intestinal Rehabilitation in the NICU

2020 ◽  
Vol 25 (Supplement_2) ◽  
pp. e13-e13
Author(s):  
Keerat Dhaliwal ◽  
Susan Albersheim ◽  
Linda Casey

Abstract Background Many children with intestinal failure (IF) start their course in the NICU with medical or surgical conditions limiting enteral feeding. Multidisciplinary intestinal rehabilitation teams have improved outcomes in pediatric IF patients, but this is not well described in neonates. Objectives NeoCHIRP represents a unique IR Team; this study describes its roles in collaborating neonatal and IR care. Design/Methods Retrospective descriptive chart review of neonates at risk for IF in one NICU, of patients admitted between April 1, 2013 and March 31, 2019. All neonates at risk for IF were evaluated weekly by a multidisciplinary Neonatal Children’s IR program in the NICU (NeoCHIRP) that is composed of surgeons, dieticians, neonatologists, IR paediatrician, nurses and patient families, to evaluate nutritional status, and provide recommendations. Data collected included weight, patient characteristics, number of NeoCHIRP visits, type of recommendations, cholestasis interventions, successful oral tolerance, and survival. Results There were 163 patients, 105 males, 58 females with 1-27 weekly visits (mean= 9.1) and gestational age between 23-43 4/7 weeks (median= 35). There were 153 survivors discharged from the NICU and 10 deaths (3 from IF related complications.) Enteral autonomy was achieved by 139/163 patients (85.3%.) Common recommendations made were enteral feeds (96.3%), parenteral nutrition (95%) or sodium management (93.9%.) Recommendations for oral stimulation were made in 79.1%, of which 40.5% (66/163) were exclusively orally fed and 20.2% partially orally fed by discharge. Cholestasis interventions were made in 66.9% and conjugated bilirubin (CB) <15 at discharge in 93 patients (range 0-123, mean 12.9 median 2) with only 23/163 patients with CB >30 at final visit. Evaluation of patient weights showed increased z-scores in only 23/153 (15%) from birth to discharge versus increased z-scores in 51/141 (36.2%) from NeoCHIRP consult to discharge. Conclusion A Multidisciplinary Neonatal Intestinal Failure Team is a useful collaborative model to support NICU medical management, by minimizing poor weight gain, cholestasis and oral aversion. Recommendations made for all NeoCHIRP patients in enteral, parenteral and sodium management resulted in improved weight gain of patients.

Obesity ◽  
2017 ◽  
Vol 25 (10) ◽  
pp. 1691-1698 ◽  
Author(s):  
Karen C. Johnson ◽  
Fridtjof Thomas ◽  
Phyllis Richey ◽  
Quynh T. Tran ◽  
Fran Tylavsky ◽  
...  

2020 ◽  
Author(s):  
Santosh Lamichhane ◽  
Alex M. Dickens ◽  
Partho Sen ◽  
Heikki Laurikainen ◽  
Jaana Suvisaari ◽  
...  

AbstractPatients with schizophrenia have a lower than average life span, largely due to the increased prevalence of cardiometabolic co-morbidities. Identification of individuals with psychotic disorders with a high risk of rapid weight gain, and the associated development of metabolic complications, is an unmet need as regards public health. Here, we applied mass spectrometry-based lipidomics in a prospective study comprising 48 controls (CTR), 44 first-episode psychosis (FEP) patients and 22 individuals at clinical-high-risk (CHR) for psychosis, from two study centers (Turku/Finland and London/UK). Baseline serum samples were analyzed by lipidomics, while body mass index (BMI) was assessed at baseline and after 12 months. We found that baseline triacylglycerols with low double bond counts and carbon numbers were positively associated with the change in BMI at follow-up. In addition, a molecular signature comprised of two triacylglycerols (TG(48:0) and TG(45:0)), was predictive of weight gain in individuals with a psychotic disorder, with an area under the receiver operating characteristic curve (AUROC) of 0.74 (95% CI: 0.60–0.85). When independently tested in the CHR group, this molecular signature predicted said weight change with AUROC = 0.73 (95% CI: 0.61–0.83). We conclude that molecular lipids may serve as a predictor of weight gain in psychotic disorders in at-risk individuals, and may thus provide a useful marker for identifying individuals who are most prone to developing cardiometabolic co-morbidities.


PEDIATRICS ◽  
1991 ◽  
Vol 88 (6) ◽  
pp. A32-A32

In the article "Can Adolescent Suicide Attempters Be Distinguished From At-Risk Adolescents?" by Swedo et al (Pediatrics 1991;88:620-629), some revisions were not made in Table 2. The corrected Table 2 follows. [See table in the PDF file]


2019 ◽  
Vol 32 ◽  
pp. 64-71.e2 ◽  
Author(s):  
Junxiu Liu ◽  
Nansi S. Boghossian ◽  
Edward A. Frongillo ◽  
Bo Cai ◽  
Linda J. Hazlett ◽  
...  

Author(s):  
Ashlee M. Cerda ◽  
Emily A. McCourt ◽  
Tamara Thevarajah ◽  
Erica Wymore ◽  
Anne M. Lynch ◽  
...  

2017 ◽  
Vol 101 ◽  
pp. S152
Author(s):  
Andre Lee ◽  
Mariana Hollanda Martins Da Rocha ◽  
Lidiane Catalani Casanova ◽  
Maria Carolina Gonçalves Dias ◽  
Marcia Lucia De Mario Marin ◽  
...  

2018 ◽  
Vol 148 (7) ◽  
pp. 1135-1143 ◽  
Author(s):  
Ivonne Ramirez-Silva ◽  
Juan A Rivera ◽  
Belem Trejo-Valdivia ◽  
Aryeh D Stein ◽  
Reynaldo Martorell ◽  
...  

AbstractBackgroundRapid early weight gain has been associated with increased risk of obesity and cardiometabolic alterations, but evidence in low and middle-income countries is inconclusive.ObjectiveWe evaluated the relation between relative weight gain from 1 to 48 mo with adiposity and cardiometabolic risk factors at 4–5 y of age, and determined if adiposity is a mediator for cardiometabolic alterations.MethodsWe studied 428 Mexican children with anthropometric and blood pressure (BP) information from birth to 5 y of age from POSGRAD (Prenatal Omega-3 fatty acid Supplementation and child GRowth And Development), of whom 334 provided measures of adiposity and cardiometabolic risk markers at 4 y. We estimated relative weight gain by means of conditional weight-for-height z scores for the age intervals 1–6, 6–12, 12–24, and 24–48 mo. Associations between relative weight gain and adiposity and cardiometabolic risk markers (lipid profile, triglycerides, insulin, glucose, and BP) were analyzed by multivariate multiple linear models and path analysis.ResultsA 1-unit increase in conditional weight-for-height z score within each age interval was positively associated with adiposity at 5 y, with coefficients of 0.43–0.89 for body mass index (BMI) z score, 1.08–3.65 mm for sum of skinfolds, and 1.21–3.87 cm for abdominal circumference (all P < 0.01). Positive associations were documented from ages 6 to 48 mo with systolic BP (coefficient ranges: 1.19–1.78 mm Hg; all P < 0.05) and from ages 12 to 48 mo with diastolic BP (1.28–0.94 mm Hg; P < 0.05) at 5 y. Conditional weight-for-height z scores at 12–24 and 24–48 mo of age were more strongly associated with adiposity and BP relative to younger ages. A unit increase in conditional weight-for-height z scores from 12 to 24 mo was associated with 14% higher insulin levels (P < 0.05) at 4 y. Path analyses documented that the associations of conditional weight gain with BP were mediated by BMI and sum of skinfolds.ConclusionRelative weight gain at most periods during the first 4 y of life was associated with greater adiposity and higher systolic and diastolic BP at 5 y. These associations with BP were mediated by adiposity. Relative weight gain from 12 to 24 mo was associated with increased serum insulin concentrations at 4 y, but there were no associations with lipid profiles or glucose concentration.


2014 ◽  
Vol 29 (1) ◽  
pp. 11-21 ◽  
Author(s):  
Lisa M. Bodnar ◽  
Jennifer A. Hutcheon ◽  
Sara M. Parisi ◽  
Sarah J. Pugh ◽  
Barbara Abrams

Sign in / Sign up

Export Citation Format

Share Document