Biomedical, psychological, environmental and behavioural factors associated with adult obesity in a nationally representative sample

Abstract Objective To identify personality, biomedical and behavioural factors associated with adult obesity in a large longitudinal sample. Method In total, 5360 participants with data on personality, neurological functioning, maternal smoking during pregnancy, education and occupation, physical exercise, adult self-reported BMI and obesity were included in the study. Obesity at 55 years was the outcome variable. Results The rates of obesity increased from 9.5 to 22.8% from age 33 to 55 years. Logistic regression analyses (adjusted estimates) showed that childhood neurological functioning (OR = 1.32: 1.07–1.63, P < 0.01), maternal smoking during pregnancy (OR = 1.42: 1.22–1.65, P < 0.001), educational qualifications (OR = 0.54: 0.37–0.79, P < 0.01), trait conscientiousness (OR = 0.80:0.74–0.86, P < 0.001) and physical exercise (OR = 0.87: 0.82–0.92, P < 0.001) were significant predictors of obesity at age 55 years for both men and women. Trait extraversion for men (OR = 1.16: 1.07–1.26, P < 0.001) and trait emotional stability for women (OR = 0.90: 0.82–0.99, P < 0.05) were also significant predictors of the outcome variable. Conclusion Biomedical, psychological, environmental and behavioural factors were all associated with adult obesity.

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454. Perinatal Risk Factors Associated with Skin Infection Hospitalisation in Western Australian Aboriginal and Non-Aboriginal Children

Open Forum Infectious Diseases ◽

10.1093/ofid/ofz360.527 ◽

2019 ◽

Vol 6 (Supplement_2) ◽

pp. S223-S223

Author(s):

Rosanne Barnes ◽

Asha C Bowen ◽

Roz Walker ◽

Steven Y C Tong ◽

Jodie McVernon ◽

...

Keyword(s):

Risk Factors ◽

Maternal Smoking ◽

Skin Infection ◽

Perinatal Risk Factors ◽

Perinatal Risk ◽

Smoking During Pregnancy ◽

Factors Associated ◽

Maternal Smoking During Pregnancy ◽

Aboriginal Children ◽

Western Australian

Abstract Background Hospitalisation with skin infection in Western Australian (WA) Aboriginal children is common, with the highest rates in infants and children from remote WA. We aimed to quantify infant, maternal, and sociodemographic risk factors for skin infection hospitalization in WA children, focusing on Aboriginal children aged <17 years. Methods We conducted a retrospective population-based cohort study with linked perinatal and hospitalization data on WA-born children (1996–2012), of whom 31,348 (6.7%) were Aboriginal. We used Cox regression to calculate adjusted hazard ratios and associated population attributable fractions (PAFs) for perinatal factors attributed to the first hospitalization with skin infection. To identify specific risk factors for early-onset infection, we further restricted the cohort to infants aged <1 year. Results Overall, 5,439 (17.4%) Aboriginal and 6,750 (1.5%) non-Aboriginal children were hospitalized at least once with a skin infection. Aboriginal infants aged <1 year had the highest skin infection hospitalization rate (63.2/1,000 child-years). The strongest risk factors in Aboriginal children aged <17 years were socio-economic disadvantage, very remote location at birth and multi-parity (≥3 previous pregnancies) accounting for 24%, 23% and 15% of skin infection hospitalizations, respectively. Other risk factors included maternal age <20 years, maternal smoking during pregnancy and low birthweight. Conclusion We have quantified the relative influence of perinatal risk factors associated with skin infection hospitalizations in WA children, providing measures indicating which factors have the potential to reduce the most hospitalizations. Our evidence supports existing calls for substantial government investment in addressing underlying social and environmental barriers to healthy skin in WA Aboriginal children but also identifies potential areas to target health promotion messaging at individuals/families on maternal smoking during pregnancy and skin hygiene for families. Disclosures All authors: No reported disclosures.

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