Trabecular bone score as an assessment tool to identify the risk of osteoporosis in axial spondyloarthritis: a case–control study

ObjectiveTo evaluate the clinical characteristics of juvenile-onset non-radiographic axial spondyloarthritis (nr-axSpA) and to investigate risk factors associated with progression to juvenile-onset ankylosing spondylitis (JoAS).MethodsA nested case–control study was conducted using the retrospectively collected data of 106 patients with juvenile-onset nr-axSpA (age at disease onset, <16 years) in the Clinical characteristic and Outcome in Chinese Axial Spondyloarthritis study cohort. Baseline demographic and clinical characteristics and prognosis were reviewed. Logistic regression analyses were performed to investigate risk factors associated with progression to JoAS.ResultsOverall, 58.5% of patients with juvenile-onset nr-axSpA presented with peripheral symptoms at disease onset. In 82.1% of these patients, axial with peripheral involvement occurred during the disease course. The rate of disease onset at >12 years and disease duration of ≤10 years were significantly higher in those with progression to JoAS than in those without progression to JoAS (83.0% vs 52.8%, p=0.001; 92.5% vs 56.6%, p<0.001, respectively). Multivariable logistic regression analysis revealed that inflammatory back pain (IBP) (OR 13.359 (95% CI 2.549 to 70.013)), buttock pain (OR 10.171 (95% CI 2.197 to 47.085)), enthesitis (OR 7.113 (95% CI 1.670 to 30.305)), elevated baseline C reactive protein (CRP) levels (OR 7.295 (95% CI 1.984 to 26.820)) and sacroiliac joint-MRI (SIJ-MRI) positivity (OR 53.821 (95% CI 9.705 to 298.475)) were significantly associated with progression to JoAS.ConclusionPeripheral involvement was prevalent in juvenile-onset nr-axSpA. IBP, buttock pain, enthesitis, elevated baseline CRP levels and SIJ-MRI positivity in patients with the disease are associated with higher risk of progression to JoAS.

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Subchondral trabecular bone morphology changes following ACL injury: a matched case-control study

Osteoarthritis and Cartilage ◽

10.1016/j.joca.2014.02.608 ◽

2014 ◽

Vol 22 ◽

pp. S328

Author(s):

B.D. Beynnon ◽

C.E. Birch ◽

K.S. Mensch ◽

M.J. DeSarno ◽

M. Gardner-Morse ◽

...

Keyword(s):

Trabecular Bone ◽

Case Control Study ◽

Acl Injury ◽

Case Control ◽

Bone Morphology ◽

Matched Case ◽

Matched Case Control Study ◽

Control Study ◽

Morphology Changes

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Cortical and Trabecular Bone Analysis of Patients With High Bone Mass From the Barcelona Osteoporosis Cohort Using 3-Dimensional Dual-Energy X-ray Absorptiometry: A Case-Control Study

Journal of Clinical Densitometry ◽

10.1016/j.jocd.2017.05.012 ◽

2018 ◽

Vol 21 (4) ◽

pp. 480-484

Author(s):

Guillermina Orduna ◽

Ludovic Humbert ◽

Roger Fonolla ◽

Jordi Romera ◽

M.Lourdes Cos ◽

...

Keyword(s):

Bone Mass ◽

Trabecular Bone ◽

Case Control Study ◽

Case Control ◽

Dual Energy ◽

High Bone Mass ◽

X Ray ◽

3 Dimensional ◽

High Bone ◽

Control Study

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Utility of a brief assessment tool developed from the Dizziness Handicap Inventory to screen for Cervicogenic dizziness: A case control study

Musculoskeletal Science and Practice ◽

10.1016/j.msksp.2017.03.008 ◽

2017 ◽

Vol 30 ◽

pp. 42-48 ◽

Cited By ~ 6

Author(s):

Susan A. Reid ◽

Robin Callister ◽

Michael G. Katekar ◽

Julia M. Treleaven

Keyword(s):

Case Control Study ◽

Assessment Tool ◽

Case Control ◽

Dizziness Handicap Inventory ◽

Brief Assessment ◽

Cervicogenic Dizziness ◽

Control Study

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Neurodevelopmental Evaluation in Full-term Newborns with Neonatal Hypoxic Ischemic Encephalopathy (HIE): A Case Control Study

Bangladesh Journal of Child Health ◽

10.3329/bjch.v39i1.28352 ◽

2016 ◽

Vol 39 (1) ◽

pp. 6-13 ◽

Cited By ~ 2

Author(s):

Selina H Banu ◽

AFM Salim ◽

Rawnak Ara ◽

Roksana Akhter ◽

Naila Z Khan

Keyword(s):

Early Identification ◽

Case Control Study ◽

Assessment Tool ◽

Case Control ◽

Hypoxic Ischemic Encephalopathy ◽

Control Group ◽

Developmental Therapy ◽

And Control ◽

Ischemic Encephalopathy ◽

Control Study

Background: Newborns with Hypoxic Ischemic Encephalopathy (HIE) are at risk of neuro-developmental disabilities. Early identification of their neuro-developmental impairments (NDI), immediate intervention and reassessment might be a useful method to measure and prevent major disability. This study was performed to identify impairment in different developmental domains among the babies admitted with moderate to severe degree HIE, and evaluate their outcomes after intervention with developmental therapy and stimulation.Methodology: The exploratory case control study was conducted during April 2008 till February 2012. We enrolled 81 full-term babies admitted to the special care neonate unite with HIE as case. The control group included age and sex matched 81 babies who did not have HIE. Neurodevelopmental assessment was performed using age specific rapid neurodevelopmental assessment tool (RNDA) by trained developmental therapists (DT). Intervention with developmental therapy and stimulation was provided for every child. Those who had assessment at least twice, (at entry and after 1 year age) were included for this study.Results: Male were predominating (66.7%). Mean age was 18 and 19 days on the 1st ; 17 and18 months on last assessment day in case and control group respectively. NDI was identified in 89% and 35% in case and control group respectively. On last assessment, 42% developed disability (permanent functional deficit), 35.8% achieved age appropriate developmental skills, 20% were lost to follow up, and 2 children died among the case group. These were 16% (13/81), 72% and 12% respectively among the control group. Significant correlation was found between the 1st and last assessment result among the case and control group.Conclusion: Early identification of NDI using a valid assessment tool and immediate intervention could probably reduce the disability in babies with HIE. A long time evaluation of this cohort would provide valuable information.Bangladesh J Child Health 2015; VOL 39 (1) :6-13

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Waist: Hip ratio is a more reliable risk assessment tool for acute myocardial infarction: A hospital based case – control study among rural Maharashtra, India

Asian Journal of Medical Sciences ◽

10.3126/ajms.v8i2.16459 ◽

2017 ◽

Vol 8 (2) ◽

pp. 38-43

Author(s):

Mohite Rajsinh ◽

Mohite Vashali ◽

Mohamad Fathni Bin Fadzli ◽

Mohamad Izzat Shafiq Azizan ◽

Mohamad Farhan Bin Ahmad Safian ◽

...

Keyword(s):

Myocardial Infarction ◽

Risk Assessment ◽

Acute Myocardial Infarction ◽

Case Control Study ◽

Assessment Tool ◽

Tertiary Care ◽

Case Control ◽

Risk Assessment Tool ◽

Waist Hip Ratio ◽

Control Study

Background: Worldwide, incidence of Acute Myocardial Infarction (AMI) has been increasing over the years and now reflected as the leading cause of death universally.Aims and Objectives: To determine the strength and degree of association between obesity indices and serum lipid profile with incidence of AMI in rural Indian population.Materials and Methods: Hospital based case-control study was conducted among newly diagnosed cases of AMI and matched controls. A total of 40 patients admitted in ICCU at rural tertiary care centre and equal number of healthy age/sex controls were enrolled in the study. Over the period of three months, by employing personal interview, anthropometric, clinical and laboratory examination information was obtained. Data were analysed by using SPSS version17 and results were expressed on Mean ± SD, Chi-Square test and Odds ratio.Results: Mean age of cases and controls was 58.5 and 60 yrs respectively with mean difference of 1.5 years. Maximum, 47.5% cases were in age 60-69 yrs and shown 1.5 times risk of getting AMI. The Overweight, Waist- Hip ratio and hyperlipidemia (cholesterol, H:L ratio and triglycerides) were significantly associated with AMI (p < 0.05 at 95% CI) and risk predicted by odd’s was of 9.3, 3.4, 2.4, 4.8, and 9.4 respectively. Every unit rise in overweight, Waist:Hip ratio, serum cholesterol, LDL and triglycerides; the risk of occurrence of AMI increases by 1.7, 2.8, 1.02, 1.01 and 1.03 times respectively.Conclusion: Study demonstrated, W:H ratio is a more valid, single, reliable risk assessment tool for AMI could be practiced at health care institutions as well as community surveillance.Asian Journal of Medical Sciences Vol.8(2) 2017 38-43

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