scholarly journals 0992 Prevalence Of Insufficient Sleep Duration And Consequences On Daytime Sleepiness, Mood And Academic Performance In Thai Adolescents

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A377-A377
Author(s):  
R Rojrattanadumrong ◽  
K K Sudnawa ◽  
W Areekul ◽  
R Jaroenying
Keyword(s):  
Depressive Symptoms ◽  
Sleep Duration ◽  
Daytime Sleepiness ◽  
Child Anxiety ◽  
Sleep Time ◽  
Poor Sleep ◽  
Insufficient Sleep ◽  
Grade Point ◽  
Thai Adolescents ◽  
Sleep Length

Abstract Introduction Insufficient sleep duration in adolescents is key public health concerns in many societies. This study aims to assess the prevalence of insufficient sleep duration and the association between short sleep with daytime sleepiness, depressive symptoms, and anxiety among Thai adolescents. Methods Thai adolescents aged 11 -18 years completed a self-administered questionnaire including Phramongkutklao Hospital Sleep disorders center Questionnaire, Pittsburg Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), The Children depress Inventory (CDI) scale and Child Anxiety Related Emotional Disorder (SCARED). Results 232 adolescents with the mean age of 14.58 (range 11-18) years participated in this survey. The average total sleep time was 7.44 hours. The overall prevalence of insufficient sleep duration (sleep duration <8 hours) was 37.5% and the small difference was found between males (42.0%) and females (32.7%). Compared with those who had a sleep length of 8 hours and more, insufficient sleep duration group exhibited higher in BMI and less in Grade Point Average (GPA). Subjective sleep insufficiency among Thai adolescent also had higher percentage of subjects with ESS ≥10 (43.2% vs 21.3%, P <0.001), depressive symptoms (56.3% vs 39.3%, P 0.012) and anxiety (54.0% vs 38.6%, P 0.022) compare to those with adequate sleep duration. Conclusion High amount of Thai adolescents with poor sleep duration were observed in the study, consistency with prior surveys. Insufficiency sleep duration group had significantly increased daytime sleepiness, mood and anxiety problems among Thai adolescents. These findings emphasized the development of interventions to improve sleep duration in Thai adolescents and more sample size should be achieved in the future. Support None

scholarly journals 1097 Sleep Disturbances, Sleep Burden, And Depressive Symptoms In US Hispanics/Latinos: Results From The HCHS/SOL Sueño Study

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A417-A418
Author(s):  
C Alcantara ◽  
M Wallace ◽  
D Sotres-Alvarez ◽  
C Vetter ◽  
A J Phillips ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Sleep Duration ◽  
Excessive Daytime Sleepiness ◽  
Daytime Sleepiness ◽  
Sleep Disturbances ◽  
The United States ◽  
Sleep Efficiency ◽  
Sensitivity Analyses ◽  
Poor Sleep ◽  
Sleep Timing

Abstract Introduction While sleep disturbances and depression often co-occur, these associations are understudied among Hispanics/Latinos. We examined the associations of sleep disturbances and sleep burden with depressive symptoms among Hispanic/Latino adults in the United States. Methods We used cross-sectional data from the Hispanic Community Health Study/Study of Latinos Sueño Ancillary study (2010-2013). The study enrolled 2072 adults (ages 18-64; 51.5% females) who completed one-week wrist-actigraphy and sleep questionnaires. Sleep burden was operationalized as the total count of sleep disturbances across six domains (duration, efficiency, midpoint, variability, insomnia, sleepiness). Depressive symptoms were assessed using the Center for Epidemiological Studies Depression scale (CESD-10). We used weighted survey linear regressions to evaluate the association of sleep disturbances and sleep burden with elevated depressive symptoms (CESD≥10) in individual models adjusted for age, gender, site, heritage, nativity, education, income, and employment. Sensitivity analyses further adjusted for behavioral health risk factors and apnea-hypopnea index. Results An estimated 28.3% had elevated depressive symptoms, 8.0% had short sleep duration (<6 hours of sleep), 10.9% had long sleep duration (>9 hours), 45.2% exhibited a later sleep midpoint (≥4:00AM), 38.4% had high sleep timing variability (upper third tertile for between day sleep midpoint), 15.3% had insomnia (ISI≥10), 17.3% had excessive daytime sleepiness (ESS ≥10), 21.5% had poor sleep efficiency (<85%), and 77.4% had a total sleep burden count of ≥0. Insomnia (ß=0.49,95%CI:.43,.56), later sleep timing (ß=0.10,95%CI:.04,.16), excessive daytime sleepiness (ß=0.19,95%CI:.11,.27), poor sleep efficiency (ß=0.09,95%CI:.02,.17), high variability (ß=0.07, 95%CI:.01,.12), and sleep burden (ß=0.11,95%CI:.09,.13), were each positively associated with elevated depressive symptoms in individual adjusted models and sensitivity analyses. Extreme sleep durations were not associated with elevated depressive symptoms. Conclusion Multiple inter-related sleep disturbances, particularly those pertaining to sleep quality and timing, are associated with depression and may be targets for future interventions aimed at improving mood among Hispanics/Latinos. Support HL127307, HL098927, HL125748

Abstract 15080: Chronic Mild Sleep Curtailment Increases Markers of Adiposity While Maintained Healthy Sleep Reduces These Measures in Women

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Faris M Zuraikat ◽  
Samantha E Scaccia ◽  
Arindam RoyChoudhury ◽  
Marie-Pierre St-Onge
Keyword(s):  
Skeletal Muscle ◽  
Body Weight ◽  
Sleep Duration ◽  
Cardiovascular Health ◽  
Sleep Time ◽  
Whole Body ◽  
Body Volume ◽  
Insufficient Sleep ◽  
Wrist Actigraphy ◽  
Sleep Condition

Introduction: Over one-third of US adults do not achieve adequate sleep duration of 7 or more h per night. Short sleep is linked to higher odds of cardiometabolic diseases, including obesity. However, whether prolonged insufficient sleep causes increased body weight or adiposity remains unclear. Objective: To compare, in women, changes in body weight and composition in response to prolonged mild sleep restriction (SR) vs maintenance of healthy, habitual sleep (HS). Methods: Women (n=55; age: 35±13 y; BMI: 25.5±3.5 kg/m 2 ) with average adequate sleep duration (total sleep time [TST]=455±23 min) took part in a randomized crossover study with two 6-wk phases: HS and SR. In HS, usual bed and wake times (determined from 2 wk wrist actigraphy and sleep logs) were maintained. In SR, TST was reduced by 1.5 h/night. Sleep was measured continuously and verified weekly for compliance. Body weight and composition were measured at 0 and 6 wk using magnetic resonance imaging (MRI). Linear-mixed models tested interactions of sleep condition with week on outcome measures. Results: Average TST was reduced in SR and unchanged in HS (-87±19 vs -7±26 min, P<0.01). Significant study condition by week interactions were observed for whole-body volume (WBV), waist circumference (WC), and skeletal muscle. In HS, WBV and WC decreased while these measures increased in SR (WBV: -0.47±0.22 vs 0.27±0.05 L, P=0.02; WC: -1.04 ± 0.78 vs 1.16 ± 0.54 cm, P=0.04). Results were similar for skeletal muscle (-0.19 ± 0.07 vs 0.17 ± 0.01 L, P<0.01). A trend for a reduction in weight was observed in HS relative to SR (-0.39±0.31 vs 0.34±0.09 kg, P=0.09). Conclusions: This is the first evidence that prolonged insufficient sleep leads to increased body size in women. Conversely, maintaining adequate sleep may improve body composition. Our data suggest that healthy sleep duration should be a key component of strategies to improve cardiovascular health in women.

scholarly journals 1092 Attention-deficit/hyperactivity Disorder Symptoms And Sleep Characteristics Within A Seasonal Affective Disorder Spectrum

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A415-A416
Author(s):  
K N Kim ◽  
D L Wescott ◽  
P L Franzen ◽  
B P Hasler ◽  
K A Roecklein
Keyword(s):  
Sleep Quality ◽  
Sleep Duration ◽  
Adhd Symptom ◽  
Symptom Severity ◽  
Daytime Sleepiness ◽  
Total Sleep Time ◽  
Sleep Time ◽  
Sleep Onset Latency ◽  
Adhd Symptoms ◽  
Depression Severity

Abstract Introduction Seasonal affective disorder (SAD) increases risk for attention-deficit/hyperactivity disorder (ADHD), although the mechanism linking SAD and ADHD is unknown. Prior research has identified insomnia and delayed sleep phase in both ADHD and SAD. We hypothesized that sleep duration and timing in SAD would be associated with the severity of ADHD symptoms. Methods Adults with SAD (n = 45) and subsyndromal SAD (S-SAD; n = 18) aged 19-66 years from Pittsburgh, PA., were assessed for ADHD symptoms, self-report sleep quality, depression severity, and daytime sleepiness in the Winter. Participants wore an Actiwatch for 4-14 days, from which we calculated sleep-onset latency, total sleep time, sleep midpoint, and sleep efficiency. We conducted a hierarchical multivariate linear regression to determine if sleep characteristics predict ADHD symptom severity in our sample while controlling for depressive symptoms. Age and gender were added in Step 1, seasonal depression severity in Step 2, actigraphy-based total sleep time, sleep onset latency, midpoint, and efficiency in Step 3, and self-reported sleep quality and daytime sleepiness in Step 4. Results Participants mostly scored in the “likely” or “highly likely” ADHD range (87.30%, n=55), higher than the national prevalence rate (4.4%). When controlling for age, gender, and depression severity, only shorter actigraphy-based total sleep time was associated with higher ADHD symptom severity (β=-0.30, p&lt;0.05). However, when self-reported sleep quality and daytime sleepiness were added as predictors, total sleep time was no longer a statistically-significant predictor of ADHD symptom severity and only daytime sleepiness predicted ADHD symptom severity (β=0.31, p&lt;0.05). Conclusion Our results suggest that individuals with SAD who experience daytime sleepiness and/or possibly shorter actigraphy-based sleep duration experience higher ADHD symptom severity. Treatments like Trans-C or CBT-I to improve daytime sleepiness and sleep duration may be indicated for SAD patients who present with comorbid ADHD symptoms. Support NIMH K.A.R. MH103303

scholarly journals 0193 Sleep Health Across Religions: A Consideration of Bidirectional Processes

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A76-A76
Author(s):  
K Fergason ◽  
W Rowatt ◽  
M K Scullin
Keyword(s):  
Mental Health ◽  
Sleep Duration ◽  
Religious Affiliation ◽  
Secondary Data ◽  
Sleep Time ◽  
Poor Sleep ◽  
Physical And Mental Health ◽  
Sleep Health ◽  
Causal Direction ◽  
Falling Asleep

Abstract Introduction The psychology of religion literature indicates that religious engagement is beneficial to physical and mental health. Such effects might be mediated by sleep health, which causally affects mood, cognitive, and immune functioning. However, few studies have investigated whether religiosity is associated with better sleep, and no studies have considered the reverse causal direction: better sleep may impact religious behaviors or perceptions. Methods We conducted a secondary data analysis of 1,501 participants in Wave 5 of the Baylor Religion Survey (BRS-5). Completed in Spring 2017, the BRS-5 used Address Based Sample methodology to derive a population-based sample. The survey included questions on religious affiliation, behaviors, and perceptions (e.g., certainty of Heaven). Additionally, participants rated their difficulty falling asleep and their average total sleep time. We investigated whether participants were meeting AASM/SRS consensus guidelines of 7–9 hours/night. Results Religious affiliation was associated with sleep duration, but not in the predicted direction. Atheists/Agnostics (73%) were significantly more likely to report meeting consensus sleep duration guidelines than religiously-affiliated individuals (65%), p&lt;.05. For example, Atheists/Agnostics reported better sleep duration than Catholics (63%, p&lt;.01) and Baptists (55%, p&lt;.001). Atheists/Agnostics also reported less difficulty falling asleep at night than Catholics (p=.02) and Baptists (p&lt;.001). The effects persisted when controlling for age and were particularly evident in members of African American congregations. Perceptions of getting into Heaven were significantly higher in participants who obtained better sleep duration, p&lt;.05, but interestingly, such beliefs/perceptions were unrelated to difficulty falling asleep at night, suggesting that better sleep may lead to these perceptions rather than vice versa. Conclusion In contrast to predictions, religious affiliation was associated with significantly poorer sleep health. Poor sleep health has implications for physical and mental health, and seemingly also religious perceptions/beliefs. Future experimental work is required to disentangle the causal direction of sleep-religiosity associations. Support The Baylor Religion Survey was supported by the John Templeton Foundation.

scholarly journals Comparing the Effects of FIFO/DIDO Workers Being Home versus Away on Sleep and Loneliness for Partners of Australian Mining Workers

2020 ◽  
Vol 2 (1) ◽  
pp. 86-98
Author(s):  
Kerrie-ann I. Wilson ◽  
Sally A. Ferguson ◽  
Amanda Rebar ◽  
Kristie-Lee Alfrey ◽  
Grace E. Vincent
Keyword(s):  
Sleep Quality ◽  
Sleep Duration ◽  
Adverse Outcomes ◽  
Poor Sleep ◽  
Poor Sleep Quality ◽  
Insufficient Sleep ◽  
Work Arrangements ◽  
Excessive Sleepiness ◽  
The Impact ◽  
At Home

Fly in Fly out/Drive in Drive out (FIFO/DIDO) is a prevalent work arrangement in the Australian mining industry and has been associated with adverse outcomes such as psychological stress, sleep disturbances, fatigue, and work/life interference. FIFO/DIDO work arrangements have the potential to not only impact the FIFO/DIDO worker, but also the partner of the FIFO/DIDO worker. However, there is sparse empirical evidence on the impact of FIFO/DIDO work arrangements on partners’ sleep and subsequent performance. Therefore, the primary aim of this study was to describe and compare partners’ sleep quality, sleep duration, sleepiness, and loneliness when the FIFO/DIDO workers were at home (off-shift) and away (on-shift). A secondary aim of this study was to examine whether differences in partners’ sleep quality and sleep duration as a result of FIFO/DIDO worker’s absence could be partially explained through the presence of dependents in the home, relationship duration, chronotype, duration in a FIFO/DIDO role, and loneliness. Self-reported questionnaires were completed by 195 female and 4 male participants, mostly aged between 18 and 44 years and who had been in a relationship with a FIFO/DIDO mining worker for more than five years. Of note, most participants subjectively reported poor sleep quality, insufficient sleep duration, excessive sleepiness, and moderate to extreme loneliness compared to the general population regardless of whether the FIFO/DIDO workers were at home or away. Compared to when the FIFO/DIDO workers were at home, partners experienced reduced sleep quality and increased loneliness when the FIFO/DIDO workers were away. Secondary analyses revealed that loneliness may partially underpin the negative effect that FIFO/DIDO workers’ absence has on sleep quality. Further research is needed to understand the factors that contribute to poor sleep quality, insufficient sleep duration, excessive sleepiness, and loneliness of FIFO/DIDO partners to inform appropriate strategies to support FIFO/DIDO partners’ health and wellbeing not only in the mining population, but other industries that incorporate similar FIFO/DIDO work arrangements (e.g., emergency services, offshore drilling, and transport).

scholarly journals Can People Sleep Too Much? Effects of Extended Sleep Opportunity on Sleep Duration and Timing

2021 ◽  
Vol 12 ◽  
Author(s):  
Elizabeth B. Klerman ◽  
Giuseppe Barbato ◽  
Charles A. Czeisler ◽  
Thomas A. Wehr
Keyword(s):  
Steady State ◽  
Sleep Duration ◽  
Rem Sleep ◽  
Sleep Time ◽  
Sleep Loss ◽  
Individual Variability ◽  
Insufficient Sleep ◽  
Normal Sleep ◽  
Sleep Amount

Many people are concerned about whether they are getting “enough” sleep, and if they can “sleep too much.” These concerns can be approached scientifically using experiments probing long-term (i.e., multi-night) sleep homeostatic processes, since homeostatic processes move the system toward its physiological setpoint (i.e., between “not enough” and “too much”). We analyzed sleep data from two human studies with sleep opportunities much longer than people usually stay in bed (i.e., conditions in which sleep homeostatic responses could be documented): sleep opportunities were 14–16 h per day for 3–28 days. Across the nights of the extended sleep opportunities, total sleep duration, Rapid Eye Movement (REM) sleep duration and non-REM sleep durations decreased and sleep latency increased. Multiple nights were required to reach approximately steady-state values. These results suggest a multi-day homeostatic sleep process responding to self-selected insufficient sleep duration prior to the study. Once steady state-values were reached, there were large night-to-night variations in total sleep time and other sleep metrics. Our results therefore answer these concerns about sleep amount and are important for understanding the basic physiology of sleep and for two sleep-related topics: (i) the inter-individual and intra-individual variability are relevant to understanding “normal” sleep patterns and for people with insomnia and (ii) the multiple nights of sleep required for recovery from insufficient sleep from self-selected sleep loss is important for public health and other efforts for reducing the adverse effects of sleep loss on multiple areas of physiology.

Abstract 63: Relation between Poor Sleep Quality and Resistant Hypertension

Hypertension ◽  
2012 ◽  
Vol 60 (suppl_1) ◽  
Author(s):  
Rosa Maria Bruno ◽  
Laura Palagini ◽  
Alessia Di Giulio ◽  
Angelo Gemignani ◽  
Stefano Taddei ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Sleep Quality ◽  
Sleep Duration ◽  
Resistant Hypertension ◽  
Antihypertensive Drugs ◽  
Multiple Logistic Regression Analysis ◽  
Poor Sleep ◽  
Poor Sleep Quality ◽  
Short Sleep Duration ◽  
Short Sleep

Purpose: Insomnia and short sleep duration have been associated with increased incidence of hypertension. However, the relationship between sleep loss and resistant hypertension (RH), has not been ascertained yet. Methods: 270 patients at first access to our Hypertension Outpatient Unit were enrolled. RH was defined according as office BP values >140/90 mmHg with 3 or more antihypertensive drugs, or controlled BP with 4 or more drugs, including a diuretic. Pittsburgh Sleep Quality Index (PSQI), and Beck Depression Inventory (BDI) were assessed. Poor sleep quality was defined as PSQI>5, mild-to-severe depressive symptoms as BDI score >10. Patients with self-reported sleep apneas or snoring were excluded (n=21). Results: Complete data were available for 234 patients (males 51%, mean age 58±13 years, BMI 26±5 kg/mq, antihypertensive treatment 84%, previous CV events 12%, diabetes 8%, smoking 15%, hypercholesterolemia 60%). Mean sleep duration was 6.4±1.6 hours, with a 49% prevalence of short sleep duration (<6 hours) and similar in both sexes. Conversely, women had higher PSQI scores (5.2 vs 3.6, p=0.03) and prevalence of poor sleep quality (46% vs 30% in men, p=0.01). Women showed also higher BDI scores (4.5 vs 1.8, p=0.006) and prevalence of depressive symptoms than men (20% vs 7%, p=0.003). RH patients (15%) had higher PSQI (5.8 vs 4.1, p=0.03), a difference shown in women (6.8 vs 4.8, p=0.04) but not in men (4.7 vs 3.5, p=0.37). The association between BDI score and RH showed a similar behavior (overall 3.6 vs 2.8, p=0.02; women 5.1 vs 3.7, p=0.03; men: 2.0 vs 1.9, p=0.53). In a multiple logistic regression analysis (including age, sex, obesity, diabetes, previous CV events, sleep duration, use of hypnotic drugs) poor sleep quality was independently associated with RH (OR 2.2, CI95% 1.1-5.3). However this relationship lost significance when also depressive symptoms were included in the model (p=0.12). Conclusions: Short sleep duration is highly prevalent in hypertensive patients. This condition is accompanied by poor sleep quality and depressive symptoms in women. Poor sleep quality is associated with a 2-fold higher probability of having RH. This association could be mediated by the presence of depressive symptoms.

Abstract MP073: Sleep Patterns and Depression in a Diverse Sample of Women from the AHA Go Red for Women Strategically Focused Research Network (SFRN)

Circulation ◽  
2017 ◽  
Vol 135 (suppl_1) ◽  
Author(s):  
Brooke Aggarwal ◽  
Ming Liao
Keyword(s):  
Depressive Symptoms ◽  
Sleep Quality ◽  
Sleep Duration ◽  
Minority Women ◽  
Poor Sleep ◽  
Sleep Patterns ◽  
Short Sleep Duration ◽  
Short Sleep ◽  
Long Sleep ◽  
Race Ethnicity

Background: Depression has been linked to increased risk of cardiovascular disease (CVD) through biological mechanisms and altered lifestyle behaviors, possibly including short and/or long sleep duration. However the relation between specific sleep components and depressive symptoms, and interaction by race/ethnicity has not been fully defined. The purpose of this study was to determine if sleep patterns including short sleep duration, poor sleep quality, and insomnia were associated with depressive symptoms in a free-living ethnically diverse population of adult women, and if they varied by racial/ethnic status. Methods: English or Spanish speaking females between the ages of 20-79 y, participating in an observational cohort study as part of the American Heart Association Go Red for Women SFRN, were included (n=50, 56% (28 of 50) non-white, mean age = 41 ±18y). Sleep patterns were assessed using the Pittsburgh Sleep Quality Index (PSQI), a validated instrument used to measure the quality and duration of sleep in adults. Presence of insomnia was measured using the Insomnia Severity Index (ISI). Depressive symptoms were assessed using the Beck Depression Inventory (BDI-II). Linear and logistic regression models were used to evaluate cross-sectional associations between sleep patterns and depression overall, and by race/ethnicity. Results: Overall, nearly one-fifth of participants had depressive symptoms (BDI II score ≤13), 18% (9 of 50) had short sleep duration (<6 hours per night), 38% (19 of 50) had poor quality sleep (PSQI score ≥5), and 40% (20 of 50) had some level of insomnia (ISI score ≥8). Mean BDI-II scores among women who slept <6 versus ≥6 hours were significantly greater (16 versus 5, p=.0003). Higher depression scores were associated with shorter sleep duration (p=.001), poorer sleep quality (p=.03), and higher insomnia severity (p<.0001) overall. There was no association between depression and long sleep (≥8 hours). When stratified by race/ethnicity, depression was significantly associated with poor sleep quality among minority women in multivariable models adjusted for demographic confounders (OR=1.42, 95% CI=1.03-1.95), but not among non-Hispanic white women. Depression was also significantly associated with insomnia severity (p<.001), and sleep duration (p=.03) among minority women only, in multivariable adjusted models stratified by race/ethnicity. Conclusions: In this diverse sample of women, sleep problems were highly prevalent. Poor sleep quality, insomnia, and short sleep duration (but not long sleep) were associated with greater depressive symptoms among minority women but not whites. These preliminary data suggest that minority women with short sleep duration may be at heightened CVD risk from depression. Future research should determine if interventions designed to improve sleep result in decreased depressive symptoms and reduced CVD risk.

652 Association Between Poor Sleep and Lymphocyte Subsets In Chronic HIV Infection

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A255-A255
Author(s):  
Priya Borker ◽  
Bernard Macatangay ◽  
Naresh Punjabi ◽  
Charles Rinaldo ◽  
Steven Wolinsky ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Count ◽  
Sleep Duration ◽  
T Lymphocyte ◽  
Lymphocyte Subsets ◽  
Total Sleep Time ◽  
Sleep Time ◽  
Poor Sleep ◽  
People Living With Hiv ◽  
Hiv Seropositive

Abstract Introduction Low CD4+ T lymphocyte counts and CD4+/CD8+ lymphocyte ratios predict mortality and cardiovascular risk among people living with HIV (PLWH). Whether polysomnographic (PSG) sleep measures impact T lymphocyte subset counts among PLWH is unknown. We sought to evaluate the association between lymphocyte subsets and PSG-derived sleep measures in a cohort with HIV seropositive men. Methods We analyzed data from HIV seropositive men who have sex with men participating in the Multicenter AIDS Cohort Study on antiretroviral therapy for &gt;1 year with undetectable (&lt;500 copies/mL) plasma HIV-1 RNA who underwent a sleep evaluation with home polysomnography. The following seven sleep parameters were examined: total sleep time (TST), sleep efficiency, sleep stage (N1, N2, N3, and REM) duration, and apnea-hypopnea index. Multivariable linear regression models adjusted for age and body mass index were used to assess whether sleep measures were associated with CD4+ T cell count, CD8+ T cell count, or CD4+/CD8+ ratio. Results Participants (n= 286) had a mean age of 55.2 ± 11.3 years, 52.8% had sleep apnea and mean CD4+ count was 728 ± 306 cells/mm3. None of the sleep measures were associated with CD4+ counts but longer TST and REM duration were associated with lower CD8+ counts and higher CD4+/CD8+ ratio. In adjusted analyses, every one hour increase in TST was associated with a 35 ± 18 cells/mm3 lower CD8+ count (p=0.049) and 6.3% elevation in CD4+/CD8+ ratio (p=0.006) while every hour increase in REM was associated with 123 ± 50 cells/mm3 lower CD8+ count (p=0.01) and 20% elevation in CD4+/CD8+ ratio (p=0.003). Conclusion In PLWH, longer total sleep time and REM sleep duration are associated with protective CD4+/CD8+ ratios due to lower CD8+ cell count. Further research is needed to assess if longer sleep duration is associated with decreased inflammatory markers. Support (if any) American Thoracic Society Academic Sleep Pulmonary Integrated Research/Clinical (ASPIRE) Fellowship

Perceived Stress and Coffee and Energy Drink Consumption Predict Poor Sleep Quality in Podiatric Medical Students

2015 ◽  
Vol 105 (5) ◽  
pp. 429-434 ◽  
Author(s):  
Mohomad Al Sawah ◽  
Naeemah Ruffin ◽  
Mohammad Rimawi ◽  
Carmen Concerto ◽  
Eugenio Aguglia ◽  
...  
Keyword(s):  
Medical Students ◽  
Sleep Quality ◽  
Perceived Stress ◽  
Daytime Sleepiness ◽  
Energy Drink ◽  
Poor Sleep ◽  
Poor Sleep Quality ◽  
Grade Point ◽  
Energy Drink Consumption ◽  
Second Year

Background A cross-sectional survey administered to first- and second-year podiatric medical students aimed to investigate the effect of coffee intake, energy drink consumption, and perceived stress on sleep quality in medical students during their preclinical studies. Methods Ninety-eight of 183 students contacted (53.6%) completed a questionnaire comprising standard instruments measuring sleep quality (Pittsburgh Sleep Quality Index), daytime sleepiness (Epworth Sleepiness scale), and perceived stress (ten-item Perceived Stress Scale). Furthermore, we investigated coffee and energy drink consumption. Logistic regression was conducted to identify factors associated with poor sleep quality and the relation between sleep quality and academic performance (grade point average). Results High prevalences of poor sleep quality, excessive daytime sleepiness, and perceived stress were reported. In addition, higher odds of developing poor sleep quality were associated with coffee and energy drink intake, perceived stress, and excessive daytime sleepiness. The total Pittsburgh Sleep Quality Index score was inversely correlated with grade point average. Conclusions First- and second-year podiatric medical students have poor sleep quality. Further research is needed to identify effective strategies to reduce stress and decrease coffee and energy drink intake to minimize their negative effect on sleep quality and academic performance in podiatric medical students.

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