Hepatosplenic schistosomiasis, the ignored morbidity: experience from a referral hospital in Ethiopia

2020 ◽  
Author(s):  
Seid Getahun Abdela ◽  
Nardos Girma Hassen ◽  
Foziya Mohammed Hussien ◽  
Abdulaziz Mohammed Yesuf ◽  
Johan van Griensven ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Cross Sectional Study ◽  
Severe Anaemia ◽  
Referral Hospital ◽  
Common Finding ◽  
Oesophageal Varices ◽  
Upper Gastrointestinal Endoscopy ◽  
Cross Sectional ◽  
Upper Gastrointestinal ◽  
Hepatosplenic Schistosomiasis

Abstract Background Hepatosplenic schistosomiasis (HSS) is an important chronic complication of Schistosoma infection. However, its diagnosis and management are complicated due to lack of evidence and uniform guidance. In this study, we described the clinical profile and management of HSS in one of Ethiopia's referral hospitals. Methods A hospital-based, cross-sectional study was conducted using the medical records of patients diagnosed with HSS based on clinical symptoms and typical ultrasound findings observed at the gastroenterology clinic of Dessie referral hospital from September 2018 to December 2019. Results A total of 55 patient files were evaluated. Most patients (n=39; 70%) presented with upper gastrointestinal bleeding and severe anaemia. Nearly three-quarters of patients were admitted and 31 (56%) received a blood transfusion. Hepatitis B coinfection was documented in 11 patients (20%). Upper gastrointestinal endoscopy was performed in 31 patients (56%), in whom large oesophageal varices with red signs were the most common finding. Among patients who had endoscopy, band ligation was carried out in 21 cases (68%). Praziquantel was administered to 11 patients (20%). Conclusion HSS causes severe complications of portal hypertension, like variceal bleeding, which are currently not adequately treated. In addition to already existing preventive efforts, we advise control programmes to also address acute management and rehabilitation of these patients.

scholarly journals Upper Gastrointestinal Endoscopy Findings in a Tertiary Centre in Pokhara: A Descriptive Cross-sectional Study

2021 ◽  
Vol 59 (234) ◽  
Author(s):  
Durga Dhunghana ◽  
Yukta Narayan REgmi
Keyword(s):  
Gastrointestinal Endoscopy ◽  
Significant Proportion ◽  
College Teaching ◽  
Cross Sectional Study ◽  
Common Finding ◽  
Upper Gastrointestinal Endoscopy ◽  
Sectional Study ◽  
Cross Sectional ◽  
Gastrointestinal Problems ◽  
Upper Gastrointestinal

Introduction: Endoscopic examination is one of the commonest procedures done in day-to-day practice in evaluating gastrointestinal problems. Esophagogastroduodenoscopy provides an excellent view of mucosal surfaces of the esophagus, stomach, and proximal duodenum. Upper gastrointestinal endoscopy is utilized for various diagnostic and therapeutic reasons. This study aimed to study the upper gastrointestinal endoscopy findings in a tertiary health care center in Pokhara. Methods: A descriptive cross-sectional study was conducted at Gandaki Medical College Teaching Hospital, Pokhara. After ethical approval from the institutional review board with Ref No: 070/2077/2078, endoscopic records of 889 patients undergoing upper gastrointestinal endoscopy from May 2018 to April 2019 were retrospectively reviewed. The convenience sampling method was used. Data entry and descriptive analysis were done in SPSS version 21.0. Descriptive statistics were performed. Results: A total of 889 patients undergoing upper gastrointestinal endoscopy during a period of 12 months period were studied. Among them, females were 472 (53.1%) and males were 417 (46.9%). The mean age of the study population was 45.6 years (SD, 16.86). The majority of the patients belonged to the age group 30 to 50 years. Gastritis was the most common finding in 452 (50.8%) cases, followed by gastroduodenal ulcer as the second commonest. Conclusions: Gastritis was the most common finding in the patients undergoing upper gastrointestinal endoscopy. A significant proportion of people had normal endoscopy findings. Optimal selection of cases is needed to avoid overuse in younger and encourage use in older populations.

scholarly journals Pattern of upper gastrointestinal diseases: an audit of 1000 cases based on endoscopic findings from a tertiary care hospital in Mysore

2018 ◽  
Vol 5 (7) ◽  
pp. 2412
Author(s):  
Shashikumar H. B. ◽  
Madhu B. S. ◽  
Motati Harshini
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Gastrointestinal Symptoms ◽  
Gastrointestinal Diseases ◽  
Cross Sectional Study ◽  
Common Finding ◽  
Care Hospital ◽  
Cross Sectional ◽  
Endoscopic Findings ◽  
Upper Gastrointestinal

Background: Fibreoptic endoscopy is a highly efficient diagnostic tool, which is now increasingly being used in the diagnosis of upper gastrointestinal diseases. This study has been carried out to evaluate the distribution of various upper gastrointestinal diseases based on endoscopic findings in a tertiary care hospital in Mysore.Methods: A cross-sectional study was conducted based on data from endoscopic register of 1000 subjects who underwent endoscopy for various upper gastrointestinal symptoms from 1st January 2017 to 31st December 2017(one year).Results: Mean age of the study population was 50.23 years (SD-15.46). Minimum age was 12 years and maximum was 88 years. About 44.7% of the study subjects belonged to 40-60 age group.61.6% of the study subjects were males. Most common indication was pain abdomen (32.1%) followed by dysphagia (22.2%). Of the 1000 study subjects 18.6% had normal findings. Most common finding was Gastritis / Duodenitis /Gastric erosions (28%). Malignant lesions were noted among 11.1%, of which esophagus and stomach are 5.4% and 4.9% respectively.Conclusions: Endoscopic diagnosis is useful for early detection of UGI diseases and helpful for their management.

scholarly journals Relationship Between GERD-Q Score with Esophagitis Findings in Endoscopy

2020 ◽  
Vol 21 (3) ◽  
pp. 177-181
Author(s):  
Billy Siahaan ◽  
Arles Arles ◽  
Wirhan Azhari
Keyword(s):  
Reflux Esophagitis ◽  
Gastrointestinal Endoscopy ◽  
Daily Practice ◽  
Cross Sectional Study ◽  
Upper Gastrointestinal Endoscopy ◽  
Cross Sectional ◽  
Validated Questionnaire ◽  
Symptoms And Signs ◽  
Upper Gastrointestinal

Background: Gastro-esophageal Reflux Disease (GERD) is a disease that is commonly found in daily practice and affecting the patients’ quality of life negatively. GERD-Q is a tool in the form of validated questionnaire that is quite useful and easy to use in daily practice to diagnose GERD by symptoms and signs especially in primary care that do not have endoscopy facilities.  This study was built to assess the correlation between GERD-Q score and esophagitis finding in upper gastrointestinal endoscopy in Pekanbaru. Method: This was a prospective cross-sectional study with sample groups of GERD-Q score ≥8 (high GERD-Q score) and GERD-Q score 8 (low GERD-Q score) which underwent upper gastrointestinal endoscopy to assess reflux esophagitis. GERD-Q score data were obtained by direct interview.Results: This study was participated by 65 subjects with reflux esophagitis and 51 non-esophagitis patients that had undergone upper gastrointestinal endoscopy procedure. The 65 subjects with reflux esophagitis were divided into groups based on severity (LA Classification), Grade A 29 subjects (45%), Grade B 23 subjects (35%), Grade C 11 subjects (16%), and Grade D 2 subjects (3%). The result of this study showed that there was a statistically significant correlation between GERD-Q score category with esophagitis findings from upper gastrointestinal endoscopy (p 0.05, PR = 2.6)Conclusion: There is a statistically significant correlation between GERD-Q score and esophagitis findings from endoscopy but no relevance in esophagitis severity.

scholarly journals Evaluation of 105 Cases of Dyspepsia by Upper Gastrointestinal Endoscopy and Ultrasonography of Hepatobiliary System in a Rural Setting

2019 ◽  
Vol 11 (2) ◽  
pp. 25-29
Author(s):  
Azizun Nessa ◽  
Muhammad Rabiul Hossain ◽  
Md Habibur Rahman ◽  
SM Mizanur Rahman ◽  
Abdullah Al Mamun ◽  
...  
Keyword(s):  
Functional Dyspepsia ◽  
Gastrointestinal Endoscopy ◽  
Cross Sectional Study ◽  
Upper Gastrointestinal Endoscopy ◽  
Sectional Study ◽  
Cross Sectional ◽  
Upper Gi ◽  
Dyspeptic Symptoms ◽  
Upper Gi Endoscopy ◽  
Upper Gastrointestinal

Introduction: Dyspepsia affects up to 40% of the general population and significantly reduces the quality of life. Dyspeptic symptoms may be associated with endoscopically negative conditions, such as functional dyspepsia, or with organic lesions like peptic ulcer and oesophagitis which are easily detected by endoscopy. On the other hand, such lesions may also be asymptomatic and there is not always a clear cause and effect relationship between endoscopic findings and symptoms. Objective: To determine the prevalence of significant endoscopic lesion and or ultrasonographic findings and their association with dyspeptic symptoms in Bangladeshi rural population. Materials and Methods: This prospective cross sectional study was carried out in Nov 2015 to Dec 2015 in a field mobile hospital of Bangladesh Army, established in Daudkandi, Comilla where total 1094 uninvestigated dyspeptic patients were invited to participate in this cross sectional study and 105 typical dyspeptic patients were finally recruited as per Rome III criteria. Participants underwent clinical assessment through a preformed structured questionnaire and non video upper gastrointestinal endoscopy (UGIE) and ultrasonogram (USG) of hepatobiliary system (HBS). Results: The mean age of 105 participants (male-29; female-76) studied was 36.51±7.26 years with female preponderance (72.38%). Predominant symptoms were epigastric pain (69.52%), flatulence (34.28%), heart burn (28.57%) and diffuse abdominal pain (22.85%). Regarding treatment 48(45.71%) patients took proton pump inhibitors (PPI), 24 patients (22.85%) took H2 receptor blocker and 13 patients (12.38%) were on antacids irregularly. Seventeen patients (16.15%) had no history of medications for dyspepsia. Most of the patients (76.19%) had symptoms of less than 5 years. Organic dyspepsia was found in 68(64.76%) and functional dyspepsia in 37(35.23%) participants. Percentage of functional dyspepsia in male was 24.13% and in female it was 39.47% and the difference was statistically significant (p<0.05). In the organic dyspepsia group, upper GI endoscopy revealed 07(6.66%) duodenal ulcer, 02(1.9%) gastric ulcer, 04(3.8%) prepyloric ulcer and other inflammatory lesions like prepyloric gastritis in 46(43.80%) patients, antral gastritis in 06(5.7%) patients, duodenitis in 08(7.61%) patients and erosive oesophagitis in 03 patients(2.86%). Further USG revealed cholelithiasis in 02(1.90%) and gall bladder (GB) polyp in 01(0.95%) participants which could be the reason for their dyspeptic symptoms. Thirty Seven (35.23%) participants had normal UGIE (and also normal USG of HBS) but they had significant dyspeptic symptoms. Conclusion: Most of the patients (64.76%) in this study had significant upper GI endoscopic findings and labeled as organic dyspepsia and combined use of upper GI endoscopy and USG of HBS provided better yield for aetiological diagnosis of dyspepsia if there is any. Journal of Armed Forces Medical College Bangladesh Vol.11(2) 2015: 25-29

scholarly journals Clinical and Endoscopic Profile of Upper Gastrointestinal Bleed: A Cross-sectional Study from a Tertiary Care Hospital in Southern India

2021 ◽  
Author(s):  
Manju Surendran ◽  
K Sunil Kumar
Keyword(s):  
Portal Hypertension ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Southern India ◽  
Oesophageal Varices ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Upper Gastrointestinal

Introduction: Acute Upper Gastrointestinal (UGI) bleed is a common potentially life threatening emergency. The aetiological profile of bleed and prognosis varies according to geographical region and availability of endoscopic facilities. Aim: To determine the clinical and endoscopic profile of UGI bleed, risk factors and prognosis in the patients. Materials and Methods: This was a cross-sectional study conducted over a period of 12 months at a tertiary care centre in Southern India. Patients admitted with history of hematemesis and melena, satisfying the inclusion criteria was taken consecutively. Clinical and endoscopic profile were noted and followed-up for six weeks. Statistical analysis was performed using chi-square test for qualitative variables and independent t-test for quantitative variables. Significance level was fixed as p-value of <0.05. Results: A total of 138 patients were studied in this period. The male to female ratio in the study was 3.5:1. The mean age was 53.5±13.17 years. The most common clinical presentation was hematemesis in 57 patients (41.3%) followed by haematemesis and melena in 46 patients (33.3%). The most common cause on endoscopy was portal hypertension-related oesophageal and gastric varices (51.4%) followed by antral gastritis (15.2%). The cause of UGI bleeding could not be identified in 5.1% in which the endoscopy was normal. Haemogram, platelet count and serum albumin were significantly lower in variceal bleed group, compared to non-variceal group. Eleven patients succumbed to death secondary to UGI bleed. Conclusion: The most common causes of UGI bleed are portal hypertension related gastric and oesophageal varices. The in-hospital mortality in the study was 7.9%.

scholarly journals ENDOSCOPIC FINDINGS IN PATIENTS PRESENTING WITH DYSPEPSIA AND ASSOCIATION OF AGE AND GENDER WITH ORGANIC DYSPEPSIA

2021 ◽  
Vol 71 (2) ◽  
pp. 567-70
Author(s):  
Safia Batool ◽  
Muhammad Usman Sajid ◽  
Jamal Waris ◽  
Shahzeb Ahmed Satti ◽  
Fayyaz Hassan ◽  
...  
Keyword(s):  
Erosive Esophagitis ◽  
Cross Sectional Study ◽  
Endoscopic Finding ◽  
Common Finding ◽  
Military Hospital ◽  
Upper Gastrointestinal Endoscopy ◽  
Cross Sectional ◽  
Age And Gender ◽  
Endoscopic Findings ◽  
And Gender

Objective: To determine frequency of general and specific endoscopic findings in patients diagnosed with dyspepsia and to determine association of age and gender with organic dyspepsia. Study Design: Cross sectional study. Place and Duration of Study: Gastroenterology department, Combined Military Hospital, Kharian, from Jul to Dec 2018. Methodology: A total of 180 patients participated in the study after being selected through non probability consecutive sampling. Age, gender and history of dysphagia, weight loss, gastrointestinal bleeding, and smoking were recorded. All underwent standard electronic video upper gastrointestinal endoscopy. Abnormal findings of inflammation, narrowing, strictures, furrowing, erosions, ulcers, atrophy, nodularity, polyps, masses and malignancy were recorded. The abnormal findings were presented as frequency and percentages. On the basis of endoscopic findings the sample was divided into two groups of functional (normal endoscopy) and organic dyspepsia. Chi-square test was selected to compare the frequencies of organic and functional dyspepsia with age and gender. Results: Majority 99 (55%) of the patients with dyspepsia had a normal endoscopic finding while in organic dyspepsia, reflux esophagitis 41 (22.8%) was the most common finding followed by gastritis 16 (8.9%), duodenal ulcer 12 (6.7%) and gastric ulcer 9 (5%). Three patients with organic dyspepsia had malignancy. Most common specific findings were non erosive esophagitis 25(30.8%). Age above 40 years and male gender was found to be statistically significantly associated with organic dyspepsia (p<0.01). Conclusion: Majority of the patients with dyspepsia have a normal endoscopic finding. There is a higher incidence of organic dyspepsia in males and in patients..................

scholarly journals Spontaneous renoalimentary fistula as a complication of upper tract urothelial carcinoma: unknown complication of a rare disease

2019 ◽  
Vol 12 (10) ◽  
pp. e231720
Author(s):  
Rahul Jena ◽  
Sanjoy Kumar Sureka ◽  
Surojit Ruidas ◽  
Hira Lal
Keyword(s):  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Clinical Symptoms ◽  
Locally Advanced ◽  
Transitional Cell ◽  
Penetrating Trauma ◽  
Upper Gastrointestinal Endoscopy ◽  
Cross Sectional ◽  
Upper Tract ◽  
Upper Gastrointestinal

Fistulae of the upper urinary tract with the alimentary tract are rare. Most cases of renoalimentary fistulae are secondary to penetrating trauma, which may be iatrogenic or due to locally invasive benign infective processes or complicated nephrolithiasis, or following surgical procedures. Spontaneous renoalimentary fistulae developing secondary to locally advanced malignancies, namely renal cell carcinoma, are very rare, and unknown due to upper tract transitional cell carcinoma. We present a case where a 60-year-old man, presented with clinical symptoms suggestive of upper gastrointestinal tract pathology, with no urological complaints and was diagnosed to have a renoalimentary fistula on cross-sectional imaging and upper gastrointestinal endoscopy with histopathology of duodenal growth biopsy showing high-grade transitional cell carcinoma. Due to unresectable nature of this mass, this patient had a gastric and biliary diversion and was started on palliative chemotherapy. Renoalimentary fistulae due to benign inflammatory causes may be treated by nephrectomy with or without resection of the involved bowel segment. However, all malignant fistulae have to be treated as locally advanced tumours and en bloc resection should be attempted whenever feasible.

scholarly journals Association of Helicobacter pylori infection with gastric carcinoma

2009 ◽  
Vol 35 (1) ◽  
pp. 7-10 ◽  
Author(s):  
M.A. Majid ◽  
T.I.M.A. Faruq ◽  
A.B.M. Bayezid Hossain
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Cross Sectional Study ◽  
Body Region ◽  
Upper Gastrointestinal Endoscopy ◽  
Rapid Urease Test ◽  
Cross Sectional ◽  
Urease Test ◽  
H Pylori ◽  
Upper Gastrointestinal

This is a cross-sectional study on 140 gastric neoplasm subjects diagnosed by upper gastrointestinal endoscopy. The commonest site of cancer was the antrum of stomach (52.86%), followed by the antrum and body (32.86%) and only body region (12.14%). Histology revealed adenocarcinoma in all patients. The associations of Helicobacter pylori with gastric cancer were studied by rapid urease test, serology and histology by Giemsa stain. The positivity of H. pylori determined by serology in 70 patients (50%) was significantly higher than those determined by histology 22 patients (15.71%). No significant association between H. pylori infection and gastric cancer was observed.Keywords: Gastric cancer; Helicobacter pylori; InfectionOnline: 20 May 2009DOI: 10.3329/bmrcb.v35i1.2315Bangladesh Med Res Counc Bull 2009; 35: 7-10

CLINICAL SYMPTOMS, BIOCHEMISTRY AND CYTOLOGY OF PLEURAL, PERITONEAL EFFUSIONS

2016 ◽  
pp. 66-71
Author(s):  
Van Mao Nguyen ◽  
Huyen Quynh Trang Pham
Keyword(s):  
Pleural Effusion ◽  
Clinical Symptoms ◽  
Cross Sectional Study ◽  
Malignant Cells ◽  
Sectional Study ◽  
Pleural Effusions ◽  
Cross Sectional ◽  
Breath Sounds ◽  
Peritoneal Effusion ◽  
Neutrophil Leukocytes

Background: The cytology and the support of clinical symptoms, biochemistry for diagnosis of the cases of effusions are very important. Objectives: - To describe some of clinical symptoms and biochemistry of effusions. - To compare the results between cytology and biochemistry by the causes of pleural, peritoneal fluids. Material & Method: A cross-sectional study to describe all of 47 patients with pleural, peritoneal effusions examinated by cytology in the Hospital of Hue University of Medicine and Pharmacy from April 2013 to January 2014. Results: In 47 cases with effusions, pleural effusion accounting for 55.32%, following peritoneal effusions 29.79% and 14.89% with both of them. The most common symptoms in patients with pleural effusions were diminished or absent tactile fremitus, dull percussion, diminished or absent breath sounds (100%), in patients with peritoneal effusions was ascites (95.24%). 100% cases with pleural effusions, 50% cases with peritoneal effusions and 80% cases with pleural and peritoneal effusions were exudates. The percentage of malignant cells in patients with pleural effusions was 26.92%, in peritoneal effusions was 28.57%, in pleural and peritoneal effusions was 42.86%. The percentage of detecting the malignant cells in patients with suspected cancer in the first test was 57.14%, in the second was 9.53% and 33.33% undetectable. Most of cases which had malignant cells and inflammatory were exudates, all of the cases which had a few cells were transudates. Besides, 7.5% cases which had high neutrophil leukocytes were transudates. Conclusion: Cytology should be carry out adding to the clinical examinations and biochemistry tests to have an exact diagnosis, especially for the malignant ones. For the case with suspected cancer, we should repeat cytology test one more time to increase the ability to detect malignant cells. Key words: Effusion, pleural effusion, peritoneal effusion, cytology, biochemistry

A Cross-Sectional Study to Evaluate Adherence to the Ten Steps to Successful Breastfeeding at a Referral Hospital in Rwanda

2018 ◽  
Author(s):  
Janvier Hitayezu ◽  
David Ntirushwa ◽  
Jean Claude Ntiyamira ◽  
Jeannette Kayitesi ◽  
Rose Mary Murungi ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Referral Hospital ◽  
Sectional Study ◽  
Cross Sectional
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