Methanolic Seed Extract of Piper Guineense Inhibits Fertility of Female Sprague Dawley Rats

2008 ◽  
Vol 22 (S2) ◽  
pp. 101-101
Author(s):  
Ibiyemi I Olatunji‐Bello ◽  
Funmileyi O Awobajo ◽  
Muibat A Ajiboye
Keyword(s):  
Seed Extract ◽  
Sprague Dawley ◽  
Piper Guineense ◽  
Sprague Dawley Rats

scholarly journals Preventive effect of Elateriospermum tapos seed extract against obese Sprague Dawley rats

2019 ◽  
Vol 20 (1) ◽  
pp. 107-113
Author(s):  
Kokila Vani Perumal ◽  
Nor Liyana Ja’afar ◽  
Santhra Segaran Balan ◽  
Azrina Zainal Abidin ◽  
Daryl J. Arapoc ◽  
...  
Keyword(s):  
Seed Extract ◽  
Preventive Effect ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

Ameliorative Effects of the Lyophilized Aqueous Seed Extract of Buchholzia coriacea on Scopolamine-Induced Memory Impairment in Sprague-Dawley Rats

2020 ◽  
Vol 11 (1) ◽  
pp. 42-52
Author(s):  
Abigail Abraham ◽  
◽  
Omonike Shonekan ◽  
Ifeoma Orabueze ◽  
Oluwatomisin Faniyan ◽  
...  
Keyword(s):  
Memory Impairment ◽  
Seed Extract ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

scholarly journals Infecund evaluation of cycling female Sprague–Dawley rats: An aftermath treatment with Momordica charantia seed extract

2012 ◽  
Vol 17 (1) ◽  
pp. 37-41 ◽  
Author(s):  
Chyke Ifeanyi Amah ◽  
Oshiozokhai Eboetse Yama ◽  
Cressie Carmel Noronha
Keyword(s):  
Seed Extract ◽  
Momordica Charantia ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

Effect of crude Moringa oleifera Lam. seed extract on the blood markers of metabolic syndrome in high-fructose diet-fed growing Sprague-Dawley rats

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Masiline Mapfumo ◽  
Busisani W. Lembede ◽  
Ashwell R. Ndhlala ◽  
Eliton Chivandi
Keyword(s):  
Body Mass ◽  
Moringa Oleifera ◽  
Seed Extract ◽  
Plasma Triglyceride ◽  
Female Rats ◽  
Male Rats ◽  
Sprague Dawley ◽  
High Fructose Diet ◽  
Sprague Dawley Rats ◽  
High Fructose

AbstractBackgroundMoringa oleifera seed has anti-diabetic and anti-obesogenic properties. This study interrogated the effect of crude hydroethanolic M. oleifera seed extract on the blood markers of metabolic syndrome (MetS) in high-fructose diet fed growing Sprague-Dawley rats.MethodsSixty 21-day old female and male Sprague-Dawley rat pups were randomly allocated to and administered one of the following treatment regimens daily for twelve weeks: group I – plain drinking water (PW)+plain gelatine cube (PC), group II – 20% (w/v) fructose solution (FS)+PC, group III – FS+100 mg/kg body mass fenofibrate in gelatine cube (FN), group IV – FS+low dose (50 mg/kg body mass) of M. oleifera in gelatine cube (LMol) and group V – FS+high dose (500 mg/kg body mass) of M. oleifera in gelatine cube (HMol). The rats in each treatment regimen had ad libitum access to a standard rat chow. After the 12-week trial, the rats were subjected to an oral glucose tolerance test and then euthanised 48 h later. Blood was collected. Plasma triglyceride, cholesterol and insulin concentration were determined. HOMA-IR was then computed.ResultsThe high-fructose diet increased (p<0.05) plasma insulin concentration and HOMA-IR in female rats only. It increased plasma triglyceride concentration in both female and male rats and plasma cholesterol concentration in male rats only. The crude hydroethanolic M. oleifera seed extract prevented the high-fructose diet-induced metabolic derangements in male and female rats.ConclusionCrude hydroethanolic M. oleifera seed extract can potentially be used as a prophylactic intervention for diet-induced MetS in children.

scholarly journals Effect of Nigella sativa L. seed extract on cisplatin-induced delay in gastric emptying in Sprague-Dawley rats

2016 ◽  
Vol 31 (5) ◽  
pp. 588-592 ◽  
Author(s):  
Ambreena Riyaz ◽  
Shahid Nazir ◽  
Mohammad Khushtar ◽  
Anuradha Mishra ◽  
Yasmeen Jahan ◽  
...  
Keyword(s):  
Gastric Emptying ◽  
Nigella Sativa ◽  
Seed Extract ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

scholarly journals Sperm quotient in Sprague–Dawley rats fed graded doses of seed extract of Momordica charantia

2011 ◽  
Vol 16 (2) ◽  
pp. 154-158 ◽  
Author(s):  
Oshiozokhai Eboetse Yama ◽  
Francis Ikechukwu Duru ◽  
Ademola Ayodele Oremosu ◽  
Abraham Adepoju Osinubi ◽  
Cressie Carmel Noronha ◽  
...  
Keyword(s):  
Seed Extract ◽  
Momordica Charantia ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

scholarly journals Effect of jackfruit seed fortification on high calcium milk on bone collagen density

2019 ◽  
Vol 4 (2) ◽  
pp. 82
Author(s):  
Aulia Ayub ◽  
Fun Nagede Adinsyah ◽  
Arum Trisnaningtyas Sugiyanto Putri ◽  
Presty Dwi Fitriani ◽  
Risma Martasuri ◽  
...  
Keyword(s):  
Collagen Fiber ◽  
Alveolar Bone ◽  
Seed Extract ◽  
Bone Collagen ◽  
Control Group ◽  
Sprague Dawley ◽  
Fiber Density ◽  
Sprague Dawley Rats ◽  
High Calcium ◽  
Significant Difference

Osteoporosis is a bone disease characterized by reduced bone mass and damage to the microarchitecture of bone tissue. One of osteoporosis types is primary type-1 osteoporosis or postmenopausal osteoporosis due to estrogen deficiency. Calcium is an important mineral that plays a central role in the formation of bone strength structure. Jackfruit seeds (Artocarpus heterophyllus) contain isoflavones that can replace the role of estrogen in the body. Fortification of jackfruit seeds and high calcium milk can be a potential alternative for the treatment of postmenopausal osteoporosis. The purpose of this study was to determine the effect of drinking high calcium milk fortified with jackfruit seed extract (Artocarpus heterophyllus) on alveolar bone collagen fiber density of menopause induced rats. Twenty-five Sprague dawley rats were included in this study. Twenty Sprague dawley rats were ovariectomized, while 5 rats were left untreated (normal control group). Seven days after ovariectomy was performed, 5 rats were treated with fortification of jackfruit seed extract and high calcium milk, 5 rats were treated with jackfruit seed extract, 5 rats were treated with high calcium milk, and 5 rats were left untreated (ovariectomized control group). The treatments were done for 28 days. The rats were euthanized and the alveolar bone was taken and processed for a histological specimen. Alveolar bone collagen fibers were observed under a binocular microscope with 100 magnification. Kruskal-Wallis result showed there was a significant difference in the alveolar bone collagen fiber density among these groups (p<0.05). Mann-Whitney U Test showed a significant difference (p<0.05) in the alveolar bone collagen fiber density of the rats treated with fortification of jackfruit seed extract and high calcium milk compared to the group treated with jackfruit seed extract, that with high calcium milk, or ovariectomized control group. No significant difference in alveolar bone collagen fiber density was found between the group treated with fortification of jackfruit seed extract and high calcium milk and the normal control group (p>0.05). In conclusion, consuming high calcium milk fortified with jackfruit seed extract increases the density of alveolar bone collagen fibers.

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