scholarly journals Preventive effect of Elateriospermum tapos seed extract against obese Sprague Dawley rats

2019 ◽  
Vol 20 (1) ◽  
pp. 107-113
Author(s):  
Kokila Vani Perumal ◽  
Nor Liyana Ja’afar ◽  
Santhra Segaran Balan ◽  
Azrina Zainal Abidin ◽  
Daryl J. Arapoc ◽  
...  
Keyword(s):  
Seed Extract ◽  
Preventive Effect ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

Preventive effect of berberine against DMBA-induced breast cancer in female Sprague Dawley rats

2017 ◽  
Vol 92 ◽  
pp. 207-214 ◽  
Author(s):  
Kalyani Chowdary Karnam ◽  
Maheswara Ellutla ◽  
Lakshmi Narendra Bodduluru ◽  
Eshvendar Reddy Kasala ◽  
Shravan Kumar Uppulapu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Preventive Effect ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

Methanolic Seed Extract of Piper Guineense Inhibits Fertility of Female Sprague Dawley Rats

2008 ◽  
Vol 22 (S2) ◽  
pp. 101-101
Author(s):  
Ibiyemi I Olatunji‐Bello ◽  
Funmileyi O Awobajo ◽  
Muibat A Ajiboye
Keyword(s):  
Seed Extract ◽  
Sprague Dawley ◽  
Piper Guineense ◽  
Sprague Dawley Rats

Ameliorative Effects of the Lyophilized Aqueous Seed Extract of Buchholzia coriacea on Scopolamine-Induced Memory Impairment in Sprague-Dawley Rats

2020 ◽  
Vol 11 (1) ◽  
pp. 42-52
Author(s):  
Abigail Abraham ◽  
◽  
Omonike Shonekan ◽  
Ifeoma Orabueze ◽  
Oluwatomisin Faniyan ◽  
...  
Keyword(s):  
Memory Impairment ◽  
Seed Extract ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

scholarly journals Infecund evaluation of cycling female Sprague–Dawley rats: An aftermath treatment with Momordica charantia seed extract

2012 ◽  
Vol 17 (1) ◽  
pp. 37-41 ◽  
Author(s):  
Chyke Ifeanyi Amah ◽  
Oshiozokhai Eboetse Yama ◽  
Cressie Carmel Noronha
Keyword(s):  
Seed Extract ◽  
Momordica Charantia ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

scholarly journals Preventive Effect of Crocin on Osteoporosis in an Ovariectomized Rat Model

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Peng-Chong Cao ◽  
Wen-Xing Xiao ◽  
Ya-Bo Yan ◽  
Xiong Zhao ◽  
Shuai Liu ◽  
...  
Keyword(s):  
Elderly Women ◽  
Osteoporosis Treatment ◽  
Therapeutic Effects ◽  
Preventive Effect ◽  
Sprague Dawley ◽  
Trabecular Microarchitecture ◽  
Sprague Dawley Rats ◽  
Oxidative Stress Status ◽  
Turnover Markers ◽  
Higher Doses

The purpose of this study was to investigate the therapeutic effects of crocin on ovariectomy-induced osteoporosis in rats. Female Sprague-Dawley rats were randomly assigned to a sham-operated group (sham) and five ovariectomy (OVX) subgroups, that is, OVX with vehicle (OVX), OVX with 17β-estradiol (E2, 25 μg/kg/day), and OVX with graded crocin doses (5, 10, or 20 mg/kg/day). Daily oral administration ofE2or crocin started 4 weeks after OVX and lasted for 16 weeks. Our results showed that crocin dose-dependently inhibited the BMD reduction of L4 vertebrae and femurs caused by OVX and prevented the deterioration of trabecular microarchitecture, which were accompanied by a significant decrease in skeletal remodeling as evidenced by the lower levels of bone turnover markers. Furthermore, crocin reversed the oxidative stress status in both serum and bone tissue. The present study indicates that the administration of crocin at higher doses over a 16-week period can prevent OVX-induced osteoporosis in rats without hyperplastic effects on the uterus, which may, at least partially, be attributed to crocin’s antioxidative property. In brief, crocin is a natural alternative for postmenopausal osteoporosis treatment in elderly women.

Effect of crude Moringa oleifera Lam. seed extract on the blood markers of metabolic syndrome in high-fructose diet-fed growing Sprague-Dawley rats

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Masiline Mapfumo ◽  
Busisani W. Lembede ◽  
Ashwell R. Ndhlala ◽  
Eliton Chivandi
Keyword(s):  
Body Mass ◽  
Moringa Oleifera ◽  
Seed Extract ◽  
Plasma Triglyceride ◽  
Female Rats ◽  
Male Rats ◽  
Sprague Dawley ◽  
High Fructose Diet ◽  
Sprague Dawley Rats ◽  
High Fructose

AbstractBackgroundMoringa oleifera seed has anti-diabetic and anti-obesogenic properties. This study interrogated the effect of crude hydroethanolic M. oleifera seed extract on the blood markers of metabolic syndrome (MetS) in high-fructose diet fed growing Sprague-Dawley rats.MethodsSixty 21-day old female and male Sprague-Dawley rat pups were randomly allocated to and administered one of the following treatment regimens daily for twelve weeks: group I – plain drinking water (PW)+plain gelatine cube (PC), group II – 20% (w/v) fructose solution (FS)+PC, group III – FS+100 mg/kg body mass fenofibrate in gelatine cube (FN), group IV – FS+low dose (50 mg/kg body mass) of M. oleifera in gelatine cube (LMol) and group V – FS+high dose (500 mg/kg body mass) of M. oleifera in gelatine cube (HMol). The rats in each treatment regimen had ad libitum access to a standard rat chow. After the 12-week trial, the rats were subjected to an oral glucose tolerance test and then euthanised 48 h later. Blood was collected. Plasma triglyceride, cholesterol and insulin concentration were determined. HOMA-IR was then computed.ResultsThe high-fructose diet increased (p<0.05) plasma insulin concentration and HOMA-IR in female rats only. It increased plasma triglyceride concentration in both female and male rats and plasma cholesterol concentration in male rats only. The crude hydroethanolic M. oleifera seed extract prevented the high-fructose diet-induced metabolic derangements in male and female rats.ConclusionCrude hydroethanolic M. oleifera seed extract can potentially be used as a prophylactic intervention for diet-induced MetS in children.

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