PEPTIC ULCER IN INFANTS UNDER ONE YEAR Of AGE

Background. Patients on chronic anticoagulation face a higher risk of peptic ulcer bleeding. In this setting, the risk-benefit equation of anticoagulation resumption remains undefined. Aims. To compare the risk of thrombosis and death between patients that resumed and did not resume anticoagulation after an index episode of peptic ulcer bleeding. The secondary objective was to compare time to re-bleeding between the groups. Methods. Retrospective cohort study of adult patients that suffered an index episode of peptic ulcer bleeding while on chronic anticoagulation. Patients were divided into two groups according to whether they resumed or not anticoagulation and were followed-up for one year. A multivariable, propensity score-adjusted Cox proportional hazards model was used to adjust for confounding. Adjusted survival curves were constructed. Results. 70 patients were included in the analysis; 64.3% were men. Median age at the time of PUB was 79 years (interquartile range (IQR): 72-83). Forty patients (57.1%) resumed anticoagulation after a median time of 15 days (IQR 5.25-41.75). Restarting anticoagulation was associated with a lower risk of thrombosis or death (hazard ratio [HR] 0.14; 95%CI 0.05-0.43) and did not increase the risk of recurrent bleeding significantly (HR 1.42; 95% CI 0.10-19.8). Conclusions. Resuming anticoagulation appears to reduce the hazard of thrombosis and death without increasing the risk of recurrent bleeding significantly.

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Pharmacotherapy of Peptic Ulcer Disease

Canadian Journal of Gastroenterology ◽

10.1155/1991/683517 ◽

1991 ◽

Vol 5 (1) ◽

pp. 21-33

Author(s):

F Molina ◽

MM Vohra ◽

CN Williams

Keyword(s):

Peptic Ulcer ◽

Relapse Rate ◽

Elderly Women ◽

Medication Cost ◽

Ulcer Disease ◽

Ulcer Relapse ◽

Patient Groups ◽

One Year ◽

Better Than

The etiology of peptic ulcer is multifactorial; except for omeprazole, all drugs used for the treatment of peptic ulcer result in healing with no statistical difference at four weeks. The healing rare increases with time for active medication and placebo, and is lower among smokers than nonsmokers for all drugs but misoprostol. Mucosal protectives (or ‘cytoprotectives’) as a group seem to have a lower relapse rate than the H2receptor antagonists at one year. Combination therapy has not yet proved to be better than single drug therapy; however, the number of studies is still small, and more clinical trials are necessary. Resistant ulcers have demonstrated that acid is one of several etiological factors and that more research is needed to elucidate the reason(s) for refractoriness. The choice of therapeutic agent is generally made according to patient compliance, medication cost, side effects, effectiveness, relapse rate and physician experience with the drug. Long term maintenance therapy is effective in the prevention of ulcer relapse and is especially recommended for selected patient groups, including patients with recurrent or bleeding ulcer, patients with concomitant nonsteroidal anti-inflammatory drug use, and elderly women. Omeprazole is the treatment of choice for moderate to severe esophagitis and should be reserved for large and resistant ulcers.

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Prevalence of Peptic Ulcer Disease among the Patients with Abdominal Pain at Tertiary Care Institute of Gujarat

Academia Journal of Surgery ◽

10.47008/ajs/2020.3.2.8 ◽

2020 ◽

Vol 3 (2) ◽

pp. 30-32

Author(s):

Rahul Charpot ◽

Jaydeep M Gadhavi

Keyword(s):

Peptic Ulcer ◽

Abdominal Pain ◽

Peptic Ulcer Disease ◽

Tertiary Care ◽

Gastric Ulcers ◽

Duodenal Ulcers ◽

Ulcer Disease ◽

Care Institute ◽

Disease Information ◽

One Year

Background: To establish the occurrence of peptic ulcer disease amid the Subjects with abdominal pain at tertiary care institute of Gujarat. Subjects and Methods: present research was performed at the Department of Surgery, tertiary care institute of Gujarat, for the period of one year in 200 patients with abdominal pain and diagnosed with peptic ulcer disease. Information was composed utilizing pre-designed questionnaire. Results:The majorities of participants was females, most were aged between 18 to 25 years. Around 97% had pain in the epigastric region. Gastric ulcers preponderate for 65% patients in current research, except refused during the later existence of the epoch, as the occurrence of duodenal ulcers stayed stable, however amplified rather the later phase. Conclusion: An extensive diversity of subjects with abdominal pain was documented amid the subjects. On the other hand, the socio-economic situation and educational levels of the Subjects with the illness were below par.

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Giant peptic ulcer perforation- omentopexy versus omental plugging: a comparative study

International Surgery Journal ◽

10.18203/2349-2902.isj20200823 ◽

2020 ◽

Vol 7 (3) ◽

pp. 787

Author(s):

Rakesh Kumar ◽

Sneh Kiran ◽

H. N. Singh Hariaudh

Keyword(s):

Peptic Ulcer ◽

Mortality Rate ◽

Randomized Study ◽

Surgical Techniques ◽

Peptic Ulcer Perforation ◽

Biliary Leak ◽

Ulcer Perforation ◽

Medical College ◽

One Year ◽

A Prospective Study

Background: Giant peptic ulcer perforation is a life-threatening surgical emergency with high mortality rate. This study compares two different surgical techniques omentopexy and omental plugging for the treatment of giant peptic perforation.Methods: This study was a prospective study comparing the efficacy of omental plugging and omentopexy. The study was done at Emergency Department of General Surgery in Nalanda Medical College and Hospital, Patna over one-year period from October 2017 to September 2018. Patients were randomly allocated to two groups: one for omental plugging (cases) and other for omentopexy (controls).Results: A prospective non-randomized study of 12 patients with giant peptic perforation (≥2 cm in diameter) was carried out over a period of 24 months. The highest incidence was seen in males over 50 years of age. Biliary leak rates were 33% in the omentopexy group compared to no leak in the omental plugging group. This rate when calculated on standard error of proportion was significant at 5% level (p<0.05). Mortality rate was higher in omentopexy group compared to omental plugging group.Conclusions: Omental plugging seems to be associated with low rates of biliary leak compared to omentopexy and hence should be the procedure of choice in giant peptic ulcer perforation compared to omentopexy.

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Fibrin sealant in peptic ulcer bleeding: A one year prospective study

Gastrointestinal Endoscopy ◽

10.1016/s0016-5107(96)80261-6 ◽

1996 ◽

Vol 43 (4) ◽

pp. 355 ◽

Cited By ~ 6

Author(s):

P. Pescatore ◽

V. John ◽

H.J. Meier-Willersen ◽

T. Gottstein ◽

B.C. Manegold

Keyword(s):

Peptic Ulcer ◽

Prospective Study ◽

Fibrin Sealant ◽

Ulcer Bleeding ◽

Peptic Ulcer Bleeding ◽

One Year

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Between ‘Savage Man’ and ‘Most Faithful Englishman’ Manteo and the Early Anglo-Indian Exchange, 1584–1590

Itinerario ◽

10.1017/s0165115300044545 ◽

2000 ◽

Vol 24 (2) ◽

pp. 146-169 ◽

Cited By ~ 1

Author(s):

Michael Leroy Oberg

Keyword(s):

North Carolina ◽

Chesapeake Bay ◽

One Year ◽

Anglo Indian

In August of 1587 Manteo, an Indian from Croatoan Island, joined a group of English settlers in an attack on the native village of Dasemunkepeuc, located on the coast of present-day North Carolina. These colonists, amongst whom Manteo lived, had landed on Roanoke Island less than a month before, dumped there by a pilot more interested in hunting Spanish prize ships than in carrying colonists to their intended place of settlement along the Chesapeake Bay. The colonists had hoped to re-establish peaceful relations with area natives, and for that reason they relied upon Manteo to act as an interpreter, broker, and intercultural diplomat. The legacy of Anglo-Indian bitterness remaining from Ralph Lane's military settlement, however, which had hastily abandoned the island one year before, was too great for Manteo to overcome. The settlers found themselves that summer in the midst of hostile Indians.

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Some Biological Applications of High Voltage Electron Microscopy

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100051505 ◽

1974 ◽

Vol 32 ◽

pp. 298-299

Author(s):

Hans Ris

Keyword(s):

High Voltage ◽

Chromosome Structure ◽

Nerve Fibers ◽

Good Resolution ◽

High Voltage Electron Microscopy ◽

Voltage Electron ◽

University Of Wisconsin ◽

High Voltage Electron ◽

One Year ◽

The University

The High Voltage Electron Microscope Laboratory at the University of Wisconsin has been in operation a little over one year. I would like to give a progress report about our experience with this new technique. The achievement of good resolution with thick specimens has been mainly exploited so far. A cold stage which will allow us to look at frozen specimens and a hydration stage are now being installed in our microscope. This will soon make it possible to study undehydrated specimens, a particularly exciting application of the high voltage microscope.Some of the problems studied at the Madison facility are: Structure of kinetoplast and flagella in trypanosomes (J. Paulin, U. of Georgia); growth cones of nerve fibers (R. Hannah, U. of Georgia Medical School); spiny dendrites in cerebellum of mouse (Scott and Guillery, Anatomy, U. of Wis.); spindle of baker's yeast (Joan Peterson, Madison) spindle of Haemanthus (A. Bajer, U. of Oregon, Eugene) chromosome structure (Hans Ris, U. of Wisconsin, Madison). Dr. Paulin and Dr. Hanna are reporting their work separately at this meeting and I shall therefore not discuss it here.

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Osseointegration interface of calcified bone and endosseous implants

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100130110 ◽

1992 ◽

Vol 50 (2) ◽

pp. 1096-1097

Author(s):

K.E. Krizan ◽

J.E. Laffoon ◽

M.J. Buckley

Keyword(s):

Structure And Function ◽

Titanium Implants ◽

En Bloc ◽

Endosseous Implants ◽

Ultrastructural Studies ◽

The Past ◽

Cacodylate Buffer ◽

One Year ◽

And Function

With increase use of tissue-integrated prostheses in recent years it is a goal to understand what is happening at the interface between haversion bone and bulk metal. This study uses electron microscopy (EM) techniques to establish parameters for osseointegration (structure and function between bone and nonload-carrying implants) in an animal model. In the past the interface has been evaluated extensively with light microscopy methods. Today researchers are using the EM for ultrastructural studies of the bone tissue and implant responses to an in vivo environment. Under general anesthesia nine adult mongrel dogs received three Brånemark (Nobelpharma) 3.75 × 7 mm titanium implants surgical placed in their left zygomatic arch. After a one year healing period the animals were injected with a routine bone marker (oxytetracycline), euthanized and perfused via aortic cannulation with 3% glutaraldehyde in 0.1M cacodylate buffer pH 7.2. Implants were retrieved en bloc, harvest radiographs made (Fig. 1), and routinely embedded in plastic. Tissue and implants were cut into 300 micron thick wafers, longitudinally to the implant with an Isomet saw and diamond wafering blade [Beuhler] until the center of the implant was reached.

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Effectiveness of a 24-hour nicotine patch in conjunction with a cognitive behavioural programme: one year outcome transdermal

Addiction ◽

10.1046/j.1360-0443.1997.921274.x ◽

1997 ◽

Vol 92 (1) ◽

pp. 27-31

Author(s):

Robyn L. Richmond ◽

Linda Kehoe ◽

Abilio Cesar De Almeida Neto

Keyword(s):

Nicotine Patch ◽

Cognitive Behavioural ◽

One Year

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