Potassium Iodate and Its Comparison to Potassium Iodide As a Blocker of 131I Uptake by the Thyroid in Rats

1993 ◽  
Vol 65 (5) ◽  
pp. 545-549 ◽  
Author(s):  
D. N. Pahuja ◽  
M. G. R. Rajan ◽  
A. V. Borkar ◽  
A. M. Samuel
Keyword(s):  
Potassium Iodide ◽  
Potassium Iodate ◽  
131I Uptake

scholarly journals Large-Scale Production of Salt Fortified with Iodine and Iron

1996 ◽  
Vol 17 (1) ◽  
pp. 1-6 ◽  
Author(s):  
S. Ranganathan ◽  
Vinodini Reddy ◽  
P. Ramamoorthy
Keyword(s):  
Potassium Iodide ◽  
Large Scale ◽  
Ferrous Sulphate ◽  
Sodium Hexametaphosphate ◽  
Common Salt ◽  
Scale Production ◽  
Mixing Process ◽  
Potassium Iodate ◽  
Large Scale Production ◽  
Dry Mixing

A new dry-mixing process for producing iodine- and iron-fortified salt on a large scale (20 30 metric tons per shift) was developed in salt factories at Valinokkam and Hyderabad, India. Common salt is mixed with 1% sodium hexametaphosphate, 0.5% ferrous sulphate heptahydrate, and 0.0055% potassium iodide or 0.007% potassium iodate in a ribbon blender. Dry mixing is superior to spray mixing and is associated with no operational problems. The fortified salt produced by this method retains the original colour of the unfortified salt, and the distribution of iodine and iron is uniform. The acceptability of the fortified salt is satisfactory, as various food preparations using the product are indistinguishable in colour, taste, and flavour from those containing unfortified salt

scholarly journals Potassium iodide, but not potassium iodate, as a potential protective agent against oxidative damage to membrane lipids in porcine thyroid

2013 ◽  
Vol 6 (1) ◽  
pp. 10 ◽  
Author(s):  
Magdalena Milczarek ◽  
Jan Stepniak ◽  
Andrzej Lewinski ◽  
Malgorzata Karbownik-Lewinska
Keyword(s):  
Oxidative Damage ◽  
Potassium Iodide ◽  
Membrane Lipids ◽  
Protective Agent ◽  
Potassium Iodate

ChemInform Abstract: Preparation of Aromatic Iodoacetyl Derivatives by Direct Iodination with a Potassium Iodide-Potassium Iodate-Sulfuric Acid System

ChemInform ◽  
2010 ◽  
Vol 23 (39) ◽  
pp. no-no
Author(s):  
T. OKAMOTO ◽  
T. KAKINAMI ◽  
T. NISHIMURA ◽  
I. HERMAWAN ◽  
S. KAJIGAESHI
Keyword(s):  
Sulfuric Acid ◽  
Potassium Iodide ◽  
Acid System ◽  
Potassium Iodate

scholarly journals Validated Spectrophotometric Method to Assay of B6 and B3 Vitamins in Pharmaceutical Forms Using Potassium Iodide and Potassium Iodate

2015 ◽  
Vol 60 ◽  
pp. 113-119 ◽  
Author(s):  
Mouhammed Khateeb ◽  
Basheer Elias ◽  
Fatema Al Rahal
Keyword(s):  
Comparative Study ◽  
Aqueous Medium ◽  
Potassium Iodide ◽  
Spectrophotometric Method ◽  
Pharmaceutical Formulations ◽  
Potassium Iodate ◽  
Pyridoxine Hydrochloride ◽  
Iodide Ions ◽  
Significant Difference

A simple, precise and reliable spectrophotometric method for the determination of pyridoxine hydrochloride (vitB6) and nicotinamide (vitB3) in pure form and pharmaceutical formulations has been described. The method is based on the reaction of studied vitamin with a mixture of potassium iodide and potassium iodate in aqueous medium at (250.5oC) to form yellow colored tri iodide ions (I3-). The reaction is followed spectrophotometrically by measuring the absorbance at 290, 335 and 288, 350 nm for vitB6 and vitB3 respectively. Beer's law was obeyed in the range of 0.5-20.0 μg mL-1 for all procedures. Molar absorptivities were found to be 1.49×104, 1.93×104 and 0.89×104, 1.25×104 L mol-1 cm-1, for determination of vitB6 and vitB3 at 290, 335 and 288, 350 nm respectively. The proposed method has been applied to determine the components in commercial forms with no interference from the excipients. A comparative study between the suggested procedures and the official methods showed no significant difference between the two methods.

Preparation of Aromatic Iodoacetyl Derivatives by Direct Iodination with a Potassium Iodide–Potassium Iodate–Sulfuric Acid System

1992 ◽  
Vol 65 (6) ◽  
pp. 1731-1733 ◽  
Author(s):  
Tsuyoshi Okamoto ◽  
Takaaki Kakinami ◽  
Tetsuo Nishimura ◽  
Irwan- Hermawan ◽  
Shoji Kajigaeshi
Keyword(s):  
Sulfuric Acid ◽  
Potassium Iodide ◽  
Acid System ◽  
Potassium Iodate

scholarly journals VALIDATED SPECTROPHOTOMETRIC METHOD TO DETERMINE VARDENAFIL AND SILDENAFIL IN PHARMACEUTICAL FORMS USING POTASSIUM IODIDE AND POTASSIUM IODATE

2017 ◽  
Vol 9 (10) ◽  
pp. 65 ◽  
Author(s):  
Amir Alhaj Sakur ◽  
Shaza Affas
Keyword(s):  
Potassium Iodide ◽  
Spectrophotometric Method ◽  
Molar Absorptivity ◽  
Dosage Forms ◽  
Potassium Iodate ◽  
Average Recovery ◽  
Beer's Law ◽  
Beer’S Law ◽  
Good Agreement

Objective: To develop and validate simple, sensitive, precise and free of organic solvents method for the determination of sildenafil (SIL) and vardenafil (VAR) in bulk and pharmaceutical formulation.Methods: The method is based on the reaction of studied drugs with a mixture of potassium iodide and potassium iodate in an aqueous medium at (25±2 °C) to form yellow coloured triiodide ions (I3-) within 45 min. The reaction is followed spectrophotometrically by measuring the absorbance at 288, 351 nm and 285, 351 nm for sildenafil and vardenafil respectively.Results: The effects of analytical parameters on the reported systems were investigated. Beer's law of SIL was obeyed in the range of (0.4-12) μg ml-1and (0.6-16) μg ml-1. Molar absorptivity was found to be (67.659 ×103) lmol/cmand (37.955×103) lmol/cm at 288 nm, 351 nm respectively. Beer's law of VAR was obeyed in the range of (0.2-13) μg/mland (0.5-40) μg/ml. Moreover, molar absorptivity’s were found to be (68.719 ×103) l mol-1 cm-1and (26.691×103) l mol-1 cm-1 at 285 nm, 351 nm respectively.Conclusion: The proposed method has been applied to determine the components in dosage forms with an average recovery of 98.15% to 103.45% and the results have been found in good agreement with those results obtained by the reference methods.

PHOTOMETRIC MICRODETERMINATION OF CALCIUM

1947 ◽  
Vol 25b (5) ◽  
pp. 449-454 ◽  
Author(s):  
H. A. DeLuca
Keyword(s):  
Hydrochloric Acid ◽  
Potassium Iodide ◽  
Photometric Determination ◽  
Calibration Data ◽  
Iodine Solution ◽  
Potassium Iodate

A method is described for the photometric determination of amounts of calcium ranging from 0.04 to 0.16 mgm. The calcium is precipitated as the oxalate. The latter is converted to the carbonate by heating at 475° to 500 °C. for one hour. The carbonate is dissolved in 1 ml. of 0.01 N hydrochloric acid. The excess acid is allowed to liberate iodine by reacting with potassium iodate and potassium iodide. The absorption of the iodine solution is measured by use of an Evelyn colorimeter, and the calcium originally present in the sample is determined from calibration data.

Morphological Observations on the Granule Types in Rabbit Extra-Adrenal Chromaffin Cells.

1975 ◽  
Vol 33 ◽  
pp. 318-319
Author(s):  
Joe A. Mascorro ◽  
Robert D. Yates
Keyword(s):  
Chromaffin Cells ◽  
Sodium Phosphate ◽  
Ganglion Cells ◽  
Ultrastructural Level ◽  
Osmic Acid ◽  
Adrenal Chromaffin Cells ◽  
Potassium Iodate ◽  
Perfusion Fluid ◽  
New Zealand White Rabbits ◽  
Adrenal Chromaffin

Extra-adrenal chromaffin organs (abdominal paraganglia) constitute rich sources of catecholamines. It is believed that these bodies contain norepinephrine exclusively. However, the present workers recently observed epinephrine type granules in para- ganglion cells. This report investigates catecholamine containing granules in rabbit paraganglia at the ultrastructural level.New Zealand white rabbits (150-170 grams) were anesthetized with 50 mg/kg Nembutal (IP) and perfused with 3% glutaraldehyde buffered with 0.2M sodium phosphate, pH 7.3. The retroperitoneal tissue blocks were removed and placed in perfusion fluid for 4 hours. The abdominal paraganglia were dissected from the blocks, diced, washed in phosphate buffer and fixed in 1% osmic acid buffered with phosphate. In other animals, the glutaraldehyde perfused tissue blocks were immersed for 1 hour in 3% glutaraldehyde/2.5% potassium iodate buffered as before. The paraganglia were then diced, separated into two vials and washed in the buffer. A portion of this tissue received osmic acid fixation.

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