Parental Knowledge About Common Respiratory Infections and Antibiotic Therapy in Children

1999 ◽  
Vol 92 (10) ◽  
pp. 971-976 ◽  
Author(s):  
C APRIL COLLETT ◽  
DIANE E. PAPPAS ◽  
BRENT A. EVANS ◽  
GREGORY F. HAYDEN
Keyword(s):  
Antibiotic Therapy ◽  
Respiratory Infections ◽  
Parental Knowledge

scholarly journals Topical issues of inhaled antibacterial therapy of respiratory diseases in children

2018 ◽  
pp. 128-131 ◽  
Author(s):  
N. G. Kolosova ◽  
A. B. Kolosova
Keyword(s):  
Antibiotic Resistance ◽  
Antibiotic Therapy ◽  
Respiratory Diseases ◽  
Respiratory Infections ◽  
Infectious Agents ◽  
Antibiotic Resistant ◽  
Restriction Policy ◽  
Resistant Strains ◽  
Outpatient Practice ◽  
Systemic Antibiotics

Despite the fact that acute respiratory infections have viral etiology, the frequency of antibiotic prescriptions accounts for more than 70% in outpatient practice. However, the preventive administration of systemic antibiotics does not reduce the duration of the disease and the incidence of bacterial complications. In addition, the irrational use of antibiotic therapy can lead to the development of antibiotic resistance of infectious disease pathogens. The global problem of antibiotic resistance is seen as a serious threat to public health, and therefore the systemic antibiotic restriction policy is crucial, which helps to reduce the formation of antibiotic-resistant strains of infectious agents. The possibility of using local antibacterial drugs enables optimization of antibiotic therapy and reduces the risk of the development of antibiotic resistance. The article discusses the issues of use of thiamphenicol glycinate acetylcysteinate in various diseases in children.

A Survey of Parental Knowledge of Respiratory Syncytial Virus and Other Respiratory Infections in Preterm Infants

2021 ◽  
Vol 40 (1) ◽  
pp. 14-24
Author(s):  
Marianne Bracht ◽  
Fabiana Bacchini ◽  
Bosco Paes
Keyword(s):  
Respiratory Syncytial Virus ◽  
Preterm Infants ◽  
Disease Risk ◽  
Respiratory Infections ◽  
Parental Knowledge ◽  
Good Knowledge ◽  
Sources Of Information ◽  
Eligibility Criteria ◽  
Additional Information ◽  
Syncytial Virus

PurposeEvaluate parental knowledge of respiratory syncytial virus (RSV) and other respiratory infections in preterm infants.DesignSurvey.SampleFive hundred and eighty-three parents of preterm infants with generalized, Canadian provincial representation.Main OutcomeKnowledge of RSV infection, sources of information, and parental understanding of disease risk.Results97.9 percent (571/583) of the parents had heard about RSV, since they all had a preterm infant. Sixty-one percent reported having good knowledge of RSV; 19.4 percent had very good knowledge; 19.7 percent had little or no awareness of RSV-related infection. Most (86.3 percent) believed that RSV illness was a very serious condition; 13 percent recognized that it could be a major problem for their child. Principal sources of information were the nurse, doctor and pamphlets. Over 480 participants cited 3 or more sources of additional information—Internet, social media platforms, and educational sessions. Respiratory syncytial virus prophylaxis was a priority, but knowledge regarding the eligibility criteria for prophylaxis is essential.

Respiratory infections caused by Haemophilus influenzae β-lactamase positive carrying blaTEM gene

2020 ◽  
Vol 30 (Supplement_2) ◽  
Author(s):  
J Valério ◽  
H Ferreira ◽  
C Chaves ◽  
F Rodrigues ◽  
N Osório
Keyword(s):  
Antibiotic Therapy ◽  
Respiratory Infections ◽  
Clinical Pathology ◽  
Resistance Mechanisms ◽  
Important Data ◽  
Ampicillin Resistance ◽  
Phenotypic Profile ◽  
Antimicrobial Susceptibility Profile ◽  
Activity Screening ◽  
Etiological Agents

Abstract Introduction One of the main etiological agents of respiratory infections is H. Influenzae. The group of antibiotics most used to the treatment of H. influenzae infections is β-lactams. The most common β-lactam resistance is to ampicillin, characterized by the production of TEM (95%) and ROB (5%) β-lactamases, designated enzymatic resistance. Objectives Characterize the susceptibility profile of H. influenzae to β-lactam antibiotics, to evaluate the enzymatic resistance by the β-lactamase production and to correlate the phenotypic profile with the presence of the blaTEM. Methodology Total of 152 isolates of H. influenzae from respiratory infections were evaluated: 88 from expectorations, 56 from bronchial aspirates and 8 from bronchoalveolar lavage, collected in Clinical Pathology Service of Centro Hospitalar e Universitário de Coimbra. The results of the antimicrobial susceptibility profile and the β-lactamase screening were also provided. In order to investigate the blaTEM, DNA was extracted from the isolates and the detection was performed using the PCR technique. Results The prevalence of the blaTEM in the isolates was 31.6%, of these 33.3% showed resistance to ampicillin and 57.9% were positive in β-lactamase activity screening and blaTEM carriers. There was a statistically significance between the presence of the gene with ampicillin resistance and β-lactamase activity screening. Conclusion β-lactamase TEM production was the main mechanism of enzymatic resistance which demonstrates the high spread of the blaTEM among isolates of H. influenzae. The results found suggest that the negative strains for this β-lactamase but that presented β-lactamases with activity and resistance to β-lactams should have other β-lactamases as ROB or others. However strains with β-lactamase negative should have other mechanisms promoting the resistance as PBP3. This study provides important data on the antibiotic therapy, to minimize the expression of resistance mechanisms and problems associated with treatment.

Procalcitonin-guided antibiotic therapy algorithms for different types of acute respiratory infections based on previous trials

2018 ◽  
Vol 16 (7) ◽  
pp. 555-564 ◽  
Author(s):  
Philipp Schuetz ◽  
Rebekka Bolliger ◽  
Meret Merker ◽  
Mirjam Christ-Crain ◽  
Daiana Stolz ◽  
...  
Keyword(s):  
Antibiotic Therapy ◽  
Respiratory Infections ◽  
Acute Respiratory Infections ◽  
Different Types

Antibiotic therapy of acute upper respiratory tract infections and otitis media in adults

2018 ◽  
Vol 7 (1) ◽  
pp. 1-7
Author(s):  
Aleksandra Paź ◽  
Magdalena Arimowicz
Keyword(s):  
Respiratory Tract ◽  
Antibiotic Therapy ◽  
Respiratory Tract Infections ◽  
Viral Infections ◽  
Respiratory Infections ◽  
Symptomatic Treatment ◽  
Upper Respiratory Tract Infections ◽  
Upper Respiratory Tract ◽  
Upper Respiratory ◽  
Tract Infections

An estimated 50% of antibiotic prescriptions may be unjustified in the outpatient setting. Viruses are responsible for most acute respiratory tract infections. The viral infections are often self-limiting and only symptomatic treatment remains effective. Bacteria are involved in a small percentage of infections etiology in this area. In the case of a justified or documented suspicion of a bacterial infection, antibiotic therapy may be indicated. Based on the Polish „Recommendations for the management of non-hospital respiratory infections 2016”, the indications, the rules of choice, the appropriate dosing schedules and the therapy duration, in the most frequent upper respiratory tract infections in adults, have been presented. Implementation of the presented recommendations regarding our Polish epidemiological situation, will significantly reduce the tendency to abuse antibiotics, and thus will limit the spread of drug-resistant microorganisms.

scholarly journals Serum Procalcitonin Guided Antibiotic Therapy in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

2015 ◽  
Vol 3 (2) ◽  
pp. 67-70
Author(s):  
Rawshan Arra Khanam ◽  
Md Ashraful Haque ◽  
Mohammad Omar Faruq
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Antibiotic Therapy ◽  
Pulmonary Disease ◽  
Hospital Admissions ◽  
Respiratory Infections ◽  
Chronic Obstructive ◽  
Acute Phase Reactants ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients ◽  
Exacerbation Of Copd

Chronic obstructive pulmonary disease (COPD) is a preventable and treatable, but progressive disease. Hospital admissions of patients with COPD are frequently due to acute exacerbations of COPD (AECOPD). AECOPD are very common, affecting about 20% of COPD patients. The bacterial infection plays an important role in the exacerbation of COPD patients. In addition, recent studies using molecular diagnostics indicate that a substantial proportion of AECOPD are associated with viral infection. Accurate methods to differentiate viral and bacterial respiratory infections to allow targeted antibiotic therapy would be beneficial. Acute phase reactants are capable of demonstrating the inflammation; however, they cannot be employed to make a difference between bacterial and nonbacterial causes of the inflammation. Recently, measurement of procalcitonin (PCT) levels appears to be useful in order to minimize this problem.Bangladesh Crit Care J September 2015; 3 (2): 67-70

Local Treatment of Respiratory Infections with Antibiotics

1987 ◽  
Vol 21 (4) ◽  
pp. 322-329 ◽  
Author(s):  
Susan A. Stout ◽  
Hartmut Derendorf
Keyword(s):  
Drug Delivery ◽  
Antibiotic Therapy ◽  
Drug Concentration ◽  
Respiratory Infections ◽  
Local Treatment ◽  
Local Administration ◽  
Basic Principles ◽  
Local Antibiotic ◽  
Local Antibiotic Therapy ◽  
Antibiotic Delivery

Local administration of antibiotics for the treatment of respiratory infections has the potential advantage of reduced systemic toxicity and increased drug concentration at the site of infection. This article reviews the basic principles of pulmonary drug delivery using aerosols and the clinical efficacy of local antibiotic therapy of respiratory infections. Clinical studies have been conducted with locally administered aminoglycosides, penicillins, cephalosporins, and polypeptides. The results of these investigations and the pharmacokinetic aspects of pulmonary antibiotic delivery are summarized.

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