Quantitative Anatomic Measures and Comorbid Medical Illness in Late-Life Major Depression

1997 ◽  
Vol 5 (1) ◽  
pp. 15-25 ◽  
Author(s):  
Anand Kumar ◽  
David Miller ◽  
Douglas Ewbank ◽  
David Yousem ◽  
Andy Newberg ◽  
...  
Keyword(s):  
Major Depression ◽  
Late Life ◽  
Medical Illness ◽  
Anatomic Measures

scholarly journals Tissue-Specific Differences in Brain Phosphodiesters in Late-Life Major Depression

2014 ◽  
Vol 22 (5) ◽  
pp. 499-509 ◽  
Author(s):  
David G. Harper ◽  
J. Eric Jensen ◽  
Caitlin Ravichandran ◽  
Yusuf Sivrioglu ◽  
Marisa Silveri ◽  
...  
Keyword(s):  
Major Depression ◽  
Late Life ◽  
Tissue Specific

scholarly journals Physical exercise for late-life major depression

2015 ◽  
Vol 207 (3) ◽  
pp. 235-242 ◽  
Author(s):  
M. Belvederi Murri ◽  
M. Amore ◽  
M. Menchetti ◽  
G. Toni ◽  
F. Neviani ◽  
...  
Keyword(s):  
Primary Care ◽  
Major Depression ◽  
Physical Exercise ◽  
Primary Outcome ◽  
Rating Scale ◽  
Late Life ◽  
Lower Intensity ◽  
Progressive Exercise ◽  
Primary Care Patients ◽  
Hamilton Rating Scale

BackgroundInterventions including physical exercise may help improve the outcomes of late-life major depression, but few studies are available.AimsTo investigate whether augmenting sertraline therapy with physical exercise leads to better outcomes of late-life major depression.MethodPrimary care patients (>65 years) with major depression were randomised to 24 weeks of higher-intensity, progressive aerobic exercise plus sertraline (S+PAE), lower-intensity, non-progressive exercise plus sertraline (S+NPE) and sertraline alone. The primary outcome was remission (a score of $10 on the Hamilton Rating Scale for Depression).ResultsA total of 121 patients were included. At study end, 45% of participants in the sertraline group, 73% of those in the S+NPE group and 81% of those in the S+PAE group achieved remission (P = 0.001). A shorter time to remission was observed in the S+PAE group than in the sertraline-only group.ConclusionsPhysical exercise may be a safe and effective augmentation to antidepressant therapy in late-life major depression.

Defining guilt in depression: a comparison of subjects with major depression, chronic medical illness and healthy controls

2002 ◽  
Vol 68 (2-3) ◽  
pp. 307-315 ◽  
Author(s):  
Kayhan Ghatavi ◽  
Rob Nicolson ◽  
Cathy MacDonald ◽  
Sue Osher ◽  
Anthony Levitt
Keyword(s):  
Major Depression ◽  
Medical Illness ◽  
Healthy Controls ◽  
Chronic Medical Illness

Neurochemistry of late-life major depression: A pilot two-dimensional MR spectroscopic study

2004 ◽  
Vol 20 (6) ◽  
pp. 1039-1045 ◽  
Author(s):  
Nader Binesh ◽  
Anand Kumar ◽  
Sun Hwang ◽  
Jim Mintz ◽  
M. Albert Thomas
Keyword(s):  
Major Depression ◽  
Spectroscopic Study ◽  
Late Life ◽  
Two Dimensional

Time course for memory dysfunction in early-life and late-life major depression: A longitudinal study from the Juntendo university mood disorder project

2013 ◽  
Vol 151 (1) ◽  
pp. 66-70 ◽  
Author(s):  
Hitoshi Maeshima ◽  
Hajime Baba ◽  
Yoshiyuki Nakano ◽  
Emi Satomura ◽  
Yuki Namekawa ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Major Depression ◽  
Mood Disorder ◽  
Early Life ◽  
Time Course ◽  
Late Life ◽  
Memory Dysfunction
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