scholarly journals 1360: ECPR FOR OUT-OF-HOSPITAL CARDIAC ARREST PATIENTS: A RETROSPECTIVE MULTICENTER STUDY IN JAPAN

2021 ◽  
Vol 50 (1) ◽  
pp. 681-681
Author(s):  
Akihiko Inoue ◽  
Toru Hifumi ◽  
Tetsuya Sakamoto ◽  
Yasuhiro Kuroda
2020 ◽  
Vol 9 (9) ◽  
pp. 2927
Author(s):  
Hyoung Youn Lee ◽  
Dong Hun Lee ◽  
Byung Kook Lee ◽  
Kyung Woon Jeung ◽  
Yong Hun Jung ◽  
...  

We investigated the association between post-rewarming fever (PRF) and 6-month neurologic outcomes in cardiac arrest survivors. This was a multicenter study based on a registry of comatose adult (³ 18years) out-of-hospital cardiac arrest (OHCA) survivors who underwent targeted temperature management between October 2015 to December 2018. PRF was defined as peak temperature ≥ 38.0 °C within 72 h after completion of rewarming, and PRF timing was categorized as within 24, 24–48, and 48–72 h epochs. The primary outcome was neurologic outcomes at six months after cardiac arrest. Unfavorable neurologic outcome was defined as cerebral performance categories three to five. A total of 1031 patients were included, and 642 (62.3%) had unfavorable neurologic outcomes. PRF developed in 389 (37.7%) patients in 72 h after rewarming: within 24 h in 150 (38.6%), in 24–48 h in 155 (39.8%), and in 48–72 h in 84 (21.6%). PRF was associated with improved neurologic outcomes (odds ratio (OR), 0.633; 95% confidence interval (CI), 0.416–0.963). PRF within 24 h (OR, 0.355; 95% CI, 0.191–0.659), but not in 24–48 h or 48–72 h, was associated with unfavorable neurologic outcomes. Early PRF within 24 h after rewarming was associated with favorable neurologic outcomes.


2020 ◽  
Vol 46 (5) ◽  
pp. 973-982 ◽  
Author(s):  
Dirk Lunz ◽  
Lorenzo Calabrò ◽  
Mirko Belliato ◽  
Enrico Contri ◽  
Lars Mikael Broman ◽  
...  

Resuscitation ◽  
2018 ◽  
Vol 130 ◽  
pp. e42
Author(s):  
Kasper Glerup Lauridsen ◽  
Anders Schmidt ◽  
Vinay M. Nadkarni ◽  
Robert A. Berg ◽  
Leif Bach ◽  
...  

Critical Care ◽  
2021 ◽  
Vol 25 (1) ◽  
Author(s):  
Florian Reizine ◽  
Agathe Delbove ◽  
Alexandre Dos Santos ◽  
Laetitia Bodenes ◽  
Pierre Bouju ◽  
...  

Abstract Background Drowning is a global threat and one of the leading causes of injury around the world. The impact of drowning conditions including water salinity on patients’ prognosis remains poorly explored in Intensive Care Units (ICUs) patients. Methods We conducted a retrospective multicenter study on patients admitted to 14 ICUs in the west of France from January 2013 to January 2020. We first compared demographic and clinical characteristics at admission as well as clinical courses of these patients according to the salinity of drowning water. Then, we aimed to identify variables associated with 28-day survival using a Cox proportional hazard model. Results Of the 270 consecutive included patients, drowning occurred in seawater in 199 patients (73.7%) and in freshwater in 71 patients (26.3%). Day-28 mortality was observed in 55 patients (20.4%). Freshwater was independently associated with 28-day mortality (Adjusted Hazard Ratio (aHR) 1.84 [95% Confidence Interval (CI) 1.03–3.29], p = 0.04). A higher proportion of freshwater patients presented psychiatric comorbidities (47.9 vs. 19.1%; p < 0.0001) and the etiology of drowning appeared more frequently to be a suicide attempt in this population (25.7 vs. 4.2%; p < 0.0001). The other factors independently associated with 28-day mortality were the occurrence of a drowning-related cardiac arrest (aHR 11.5 [95% CI 2.51–52.43], p = 0.0017), duration of cardiopulmonary resuscitation (aHR 1.05 [95% CI 1.03–1.07], p < 0.0001) and SOFA score at day 1 (aHR 1.2 [95% CI 1.11–1.3], p < 0.0001). Conclusions In this large multicenter cohort, freshwater drowning patients had a poorer prognosis than saltwater drowning patients. Reasons for such discrepancies include differences in underlying psychiatric comorbidity, drowning circumstances and severities. Patients with initial cardiac arrest secondary to drowning remain with a very poor prognosis.


2021 ◽  
Vol 50 (1) ◽  
pp. 698-698
Author(s):  
Ryan Morgan ◽  
Adam Himebauch ◽  
Heather Griffis ◽  
Willam Quarshie ◽  
Timothy Yeung ◽  
...  

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0246898
Author(s):  
Dongwook Lee ◽  
Yongil Cho ◽  
Yujin Ko ◽  
Nam Hun Heo ◽  
Hyung Goo Kang ◽  
...  

Objectives Neuron-specific enolase (NSE) is frequently used to predict neurological outcomes in patients with hypoxic brain injury. Hanging can cause hypoxic brain damage, and survivors can suffer from neurological deficits that may impair daily activities. Here, we investigated the utility of the initial serum NSE level as a predictor of neurological outcomes in near-hanging patients with decreased consciousness. Methods This retrospective multicenter study was conducted in patients who visited the emergency department due to near-hanging injury from October 2013 to February 2019 at three university hospitals in Korea. They were divided into two groups according to the presence of out-of-hospital cardiac arrest. The neurological outcome was determined using the Cerebral Performance Category (CPC) measured at the time of discharge. Multivariate analysis was performed to determine whether initial serum NSE is an independent predictor of neurological outcome. Results Of the 70 patients included in the study, 44 showed a poor neurological outcome (CPC score = 3–5). Among the 52 patients with cardiac arrest, only 10 (19.2%) were discharged with good neurological outcome (CPC score = 1–2). In the whole cohort, a high serum NSE level was a significant predictor of poor neurological outcome (odds ratio [OR], 1.343; 95% confidence interval [CI], 1.003–1.800, p = 0.048). Among the patients with cardiac arrest, a high serum NSE level was a significant predictor of poor neurological outcome (OR, 1.138; 95% CI, 1.009–1.284, p = 0.036). Conclusions In near-hanging patients, a high initial serum NSE level is an independent predictor of poor neurological outcome.


Resuscitation ◽  
2021 ◽  
Vol 168 ◽  
pp. 52-57
Author(s):  
Ryan W. Morgan ◽  
Adam S. Himebauch ◽  
Heather Griffis ◽  
William O. Quarshie ◽  
Timothy Yeung ◽  
...  

Circulation ◽  
2018 ◽  
Vol 138 (Suppl_2) ◽  
Author(s):  
Kasper G Lauridsen ◽  
Anders S Schmidt ◽  
Vinay M Nadkarni ◽  
Robert A Berg ◽  
Leif Bach ◽  
...  

Introduction: Measured quality of CPR is often substandard compared to guideline recommendations during adult in-hospital cardiac arrest. Aim: To investigate the self-perceived CPR quality, teamwork and communication and to identify the most frequently reported challenges experienced during in-hospital cardiac arrest. Methods: Prospective multicenter study including self-reported data from resuscitation attempts treated by cardiac arrest teams in 5 Danish hospitals (1 university hospital, 4 regional hospitals). Data from October 2016 to May 2018 was included. Following each resuscitation attempt, all cardiac arrest team members were questioned by an online questionnaire, specifically on perceived CPR quality, teamwork and communication on a Likert scale. In addition, challenges experienced during the resuscitation attempt were inquired. Results: Of 491 cardiac arrests, the cardiac arrest team was actively involved in 387 cases (79%). Of 2,271 questionnaires there were 1,639 responses (response rate: 72%). Overall, 87% agreed or partially agreed that the CPR quality was optimal, 89% agreed or partially agreed that the teamwork was optimal, and 88% agreed or partially agreed that the communication was optimal. The most frequently reported challenges experienced were: too many health care providers present in the room (26%), healthcare providers poorly placed relative to each other in the room during resuscitation (16%), lacking space for resuscitation equipment (16%), problems finding resuscitation equipment (14%), problems finding the location of cardiac arrest (5%), and other challenges (10%). Challenges with too many healthcare providers in the room were associated with the total amount of persons in the room (p<0.001), amount of non-team members present (P<0.001) but not the number of members on the cardiac arrest team (p=0.70). Conclusions: During in-hospital resuscitation, most cardiac arrest team members perceive that CPR quality, teamwork, and communication are optimal. However, Challenges during resuscitation are not uncommon and include overcrowding, lack of space and problems locating resuscitation equipment.


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