Cancer Research UK Unites with Global Research Groups to Develop Treatments for Rare Cancers

AbstractBackground:Research in the applications of the principles of quantum physics in oncology has progressed significantly over the past decades; and several research groups with professionals from diverse scientific background, including electrical engineers, mathematicians, biologists, atomic physicists, computer programmers, and biochemists, are working collaboratively in an unprecedented and pioneering economic, organisational and human effort searching for a wider and more effective, potentially definitive, understanding of the cancers. It is hypothesised that the principles of quantum physics could open new and broader understanding of the cancers and the development of new effective, targeted, accurate, personalised and possibly definitive cancer treatment.Materials and methods:This paper reports on a review of recent studies in the field of the applications of the principles of quantum physics in biology, chemistry, biochemistry and quantum physics in cancer research, including quantum physics principles and cancer, quantum modelling techniques, quantum dots and its applications in oncology, quantum cascade laser histopathology and quantum computing applications.Conclusions:The applications of the principles of quantum physics in oncology, chemistry and biology are providing new perspectives and greater insights into a long-studied disease, which could result in a greater understanding of the cancers and the potential for personalised and definitive treatment methods.

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Do rare cancers deserve specific strategies for cancer research?

The Lancet Oncology ◽

10.1016/s1470-2045(10)70099-1 ◽

2010 ◽

Vol 11 (6) ◽

pp. 506-507 ◽

Cited By ~ 12

Author(s):

Paolo G Casali

Keyword(s):

Cancer Research ◽

Rare Cancers

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Fundamental Research into Thin Films in a Developing Country

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100095753 ◽

1972 ◽

Vol 30 ◽

pp. 500-501

Author(s):

J.A. Eades ◽

E. Grünbaum

Keyword(s):

Thin Films ◽

Growth Process ◽

Empirical Process ◽

Nucleation And Growth ◽

Research Groups ◽

Film Research ◽

Fundamental Research ◽

Controlled Deposition ◽

The One ◽

The University

In the last decade and a half, thin film research, particularly research into problems associated with epitaxy, has developed from a simple empirical process of determining the conditions for epitaxy into a complex analytical and experimental study of the nucleation and growth process on the one hand and a technology of very great importance on the other. During this period the thin films group of the University of Chile has studied the epitaxy of metals on metal and insulating substrates. The development of the group, one of the first research groups in physics to be established in the country, has parallelled the increasing complexity of the field.The elaborate techniques and equipment now needed for research into thin films may be illustrated by considering the plant and facilities of this group as characteristic of a good system for the controlled deposition and study of thin films.

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Atomic-level imaging of the surface structure of Ag2O

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100113160 ◽

1984 ◽

Vol 42 ◽

pp. 656-657

Author(s):

William Krakow

Keyword(s):

High Vacuum ◽

Atomic Level ◽

Ultra High Vacuum ◽

Research Groups ◽

Resolution Electron ◽

Surface Reconstructions ◽

Order Of Magnitude ◽

High Resolution Electron Microscope ◽

Saturated Structure ◽

Transmission And Reflection

In recent years electron microscopy has been used to image surfaces in both the transmission and reflection modes by many research groups. Some of this work has been performed under ultra high vacuum conditions (UHV) and apparent surface reconstructions observed. The level of resolution generally has been at least an order of magnitude worse than is necessary to visualize atoms directly and therefore the detailed atomic rearrangements of the surface are not known. The present author has achieved atomic level resolution under normal vacuum conditions of various Au surfaces. Unfortunately these samples were exposed to atmosphere and could not be cleaned in a standard high resolution electron microscope. The result obtained surfaces which were impurity stabilized and reveal the bulk lattice (1x1) type surface structures also encountered by other surface physics techniques under impure or overlayer contaminant conditions. It was therefore decided to study a system where exposure to air was unimportant by using a oxygen saturated structure, Ag2O, and seeking to find surface reconstructions, which will now be described.

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Quantitative parallel EELS spectrum imaging developed as a new tool in AEM

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s042482010013064x ◽

1992 ◽

Vol 50 (2) ◽

pp. 1202-1203

Author(s):

Gianluigi Botton ◽

Gilles L'espérance

Keyword(s):

Statistical Analysis ◽

Spatial Resolution ◽

Personal Computer ◽

Systematic Study ◽

Present Author ◽

Chemical Elements ◽

Detection Limits ◽

Research Groups ◽

Quantitative Performance ◽

Spectrum Imaging

As interest for parallel EELS spectrum imaging grows in laboratories equipped with commercial spectrometers, different approaches were used in recent years by a few research groups in the development of the technique of spectrum imaging as reported in the literature. Either by controlling, with a personal computer both the microsope and the spectrometer or using more powerful workstations interfaced to conventional multichannel analysers with commercially available programs to control the microscope and the spectrometer, spectrum images can now be obtained. Work on the limits of the technique, in terms of the quantitative performance was reported, however, by the present author where a systematic study of artifacts detection limits, statistical errors as a function of desired spatial resolution and range of chemical elements to be studied in a map was carried out The aim of the present paper is to show an application of quantitative parallel EELS spectrum imaging where statistical analysis is performed at each pixel and interpretation is carried out using criteria established from the statistical analysis and variations in composition are analyzed with the help of information retreived from t/γ maps so that artifacts are avoided.

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A Hopeful Discovery in Cancer Research

Gastroenterology ◽

10.1016/s0016-5085(49)80106-5 ◽

1949 ◽

Vol 12 (4) ◽

pp. 700-701

Author(s):

W.C.A.

Keyword(s):

Cancer Research

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The Structure of Wiggins' Interpersonal Circumplex: Cross-Cultural Studies

European Journal of Psychological Assessment ◽

10.1027//1015-5759.15.3.196 ◽

1999 ◽

Vol 15 (3) ◽

pp. 196-205 ◽

Cited By ~ 6

Author(s):

Rosario Martínez-Arias ◽

Fernando Silva ◽

Ma Teresa Díaz-Hidalgo ◽

Generós Ortet ◽

Micaela Moro

Keyword(s):

Cultural Studies ◽

Cross Cultural ◽

The Other ◽

Spanish Version ◽

Interpersonal Circumplex ◽

Research Groups ◽

Independent Research ◽

Research Results ◽

Cross Cultural Studies

Summary: This paper presents the results obtained in Spain with The Interpersonal Adjective Scales of J.S. Wiggins (1995) concerning the variables' structure. There are two Spanish versions of IAS, developed by two independent research groups who were not aware of each other's work. One of these versions was published as an assessment test in 1996. Results from the other group have remained unpublished to date. The set of results presented here compares three sources of data: the original American manual (from Wiggins and collaborators), the Spanish manual (already published), and the new IAS (our own research). Results can be considered satisfactory since, broadly speaking, the inner structure of the original instrument is well replicated in the Spanish version.

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Reflections on the Cognitive Interviewing Reporting Framework

Methodology ◽

10.1027/1614-2241/a000074 ◽

2013 ◽

Vol 9 (3) ◽

pp. 123-128 ◽

Cited By ~ 1

Author(s):

Gordon Willis ◽

Hennie Boeije

Keyword(s):

Research Design ◽

Cognitive Testing ◽

Level Of Detail ◽

Cognitive Interviewing ◽

Research Groups ◽

Research Project ◽

Reporting Framework ◽

Full Explanation ◽

Key Steps

Based on the experiences of three research groups using and evaluating the Cognitive Interviewing Reporting Framework (CIRF), we draw conclusions about the utility of the CIRF as a guide to creating cognitive testing reports. Authors generally found the CIRF checklist to be usable, and that it led to a more complete description of key steps involved. However, despite the explicit direction by the CIRF to include a full explanation of major steps and features (e.g., research objectives and research design), the three cognitive testing reports tended to simply state what was done, without further justification. Authors varied in their judgments concerning whether the CIRF requires the appropriate level of detail. Overall, we believe that current cognitive interviewing practice will benefit from including, within cognitive testing reports, the 10 categories of information specified by the CIRF. Future use of the CIRF may serve to direct the overall research project from the start, and to further the goal of evaluation of specific cognitive interviewing procedures.

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